Tuning reactive chlorine species to singlet oxygen via peroxymonosulfate synergy: Ultra-efficient electrooxidation with minimal chlorinated byproducts.

Chlorination electrooxidation (EO/Cl) systems face challenges in balancing efficient pollutant degradation with hazardous chlorinated byproduct formation and unclear formation mechanisms of active species. Here, we propose an innovative peroxymonosulfate (PMS)-mediated strategy to redirect reactive chlorine species (RCS) toward singlet oxygen (O) generation, achieving simultaneous ultra-efficient O production and chlorinated byproduct suppression. By adapting a refined quenching protocol, we identified contributions of key species (Cl/Cl, HOCl, Cl, and O), and unraveled the selective conversion mechanism of RCS to O in the EO/Cl⁻/PMS system.

Facilely prepared N-modified carbon quantum dots as microalgal photosynthesis promoters for wastewater treatment.

Microalgae-based wastewater treatment integrates wastewater purification with bioenergy recovery, aligning with the principles of the circular bioeconomy. However, the limited utilization of the solar spectrum by microalgae and light attenuation caused by wastewater turbidity constrain microalgal growth. To address these challenges, this study synthesized nitrogen-doped carbon quantum dots (N-CQDs) with down-conversion properties that convert UV light (∼380 nm) from the solar spectrum into blue light (450-475 nm) useable by microalgae, thereby enhancing their solar energy utilization efficiency.

Association between anemia and the risk of diabetic foot ulcer: A meta-analysis.

Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, and anemia is commonly observed in diabetic patients. However, the relationship between anemia and the risk of developing DFUs remains unclear.

Aim: To investigate the relationship between anemia and the risk of DFUs in diabetic patients through a meta-analysis.

Covert Communication Scheme for OOK in Asymmetric Noise Systems.

Existing covert communication schemes based on On-Off Keying (OOK) have not considered asymmetric noise environments, which limits their applicability in complex communication scenarios such as terahertz and underwater acoustic covert communications. To address this issue, this paper proposes a phase-based OOK coding scheme. In particular, the transmitter Alice can adjust the initial phase of the transmitted symbol to align the signal with the stronger noise components in asymmetric noise communication scenarios, thereby exploiting the masking effect of noise to achieve covert transmission.

Cobalt-modification on UiO-bpydc MOF facilitates ligand-to-metal charge transfer for superior visible-light photocatalytic degradation of refractory fluoroquinolone antibiotics.

Pollutant removal through green photocatalysis combined with advanced oxidation processes (AOPs) is critical for efficient wastewater treatment but is limited by poor light harvesting and inefficient oxidant activation. This study addresses these challenges through developing a Co-incorporated UiO-bpydc MOF for enhanced visible-light-driven photocatalysis via peroxymonosulfate (PMS) bridged ligand-to-metal charge transfer (LMCT). The MOF was synthesized through direct cobalt complexation into the UiO-bpydc framework for enabling visible light absorption.

Deciphering the Microbiome-Gut-Eye Axis: A Mendelian Randomization Analysis of the Causal Influence of Gut Microbiota on Myopia.

Background: The intricate relationship between the gut microbiome and myopia is increasingly recognized, underscoring the need to explore its causal dynamics. Despite emerging evidence, the influence of Gut Microbiota (GM) on ocular development remains underexplored.

Methods: This study utilized Mendelian Randomization (MR) to investigate the causal impact of GM on the development of myopia.

Antibacterial Mechanism and Flavour Impact of Ultrasound and Plasma-Activated Water Combination on in Crayfish.

is a foodborne pathogen commonly found in contaminated crayfish. In this study, the effects of ultrasound combined with plasma-activated water (US-PAW) against and on the flavour of crayfish were investigated to evaluate their impact on crayfish preservation. In vitro, US and PAW showed a significantly synergistic inhibition against growth and biofilm reformation at 7 min.

Regulating the Cu-Ce interaction of CuCeO/SAPO-34 catalysts to achieve a wide reaction temperature window for the collaborative synergistic removal of NO and toluene at low temperatures and reaction mechanisms.

Cu-Ce metal oxides were simultaneously supported on the SAPO-34, and the interaction between the CuO and CeO metal oxides was modulated by controlling the Ce/Cu ratio. Of the series of CuCe/SAPO-34 prepared, the prepared CuCe/S-34 catalyst exhibited high activity, strong stability, and good poison resistance for the synergistic removal of NO and toluene. And the CuCe/S-34 catalyst also showed the widest collaborative reaction temperature window, with a conversion > 90 % for NO, and > 70 % for toluene at 250-350 °C.

Extracellular Vesicles and Immune Activation in Solid Organ Transplantation: The Impact of Immunosuppression.

Recent advances in extracellular vesicle (EV) research in organ transplantation have highlighted the crucial role of donor-derived EVs in triggering alloimmune responses, ultimately contributing to transplant rejection. Following transplantation, EVs carrying donor major histocompatibility complex (MHC) molecules activate recipient antigen-presenting cells (APCs), initiating both alloreactive and regulatory T-cell responses. While immunosuppressive drugs are essential for preventing rejection, they may also influence the biogenesis and release of EVs from donor cells.

Photogenerated electron transfer in Ni/NiO supported on g-CN enables sustainable catalytic activation of peroxymonosulfate for emerging pollutant removal.

Emerging pollutants such as enrofloxacin (ENR), a widely used fluoroquinolone antibiotic, pose significant threats to aquatic ecosystems due to their persistence, bioaccumulation, and toxicity. This study reports the development of a stable and efficient Ni-NiO/g-CN heterojunction photocatalyst for ENR degradation under visible light and in the presence of peroxymonosulfate (PMS). The catalyst, synthesized via a templated self-assembly and hydrothermal method, achieved 98.

Network pharmacology alliance with experimental validation unveils the anti-colorectal cancer mechanism of Xianlian Jiedu decoction.

Ethnopharmacological Relevance: The Xianlian Jiedu Decoction (XLJDD), a traditional Chinese medicine (TCM) decoction, which is effective in clinical treatment of colorectal cancer (CRC). Nevertheless, the pharmacodynamic material basis and mechanism of its action have not been explored yet.

Aims Of The Study: To investigate the potential functional components and possible mechanism of XLJDD in anti-CRC.

Ultra-small quercetin-based nanotherapeutics ameliorate acute liver failure by combatting inflammation/cellular senescence cycle.

Acute liver failure (ALF) is marked by a substantial generation of reactive oxygen species (ROS), which can induce both cellular senescence and a pronounced inflammatory response. Senescent cells secrete factors collectively termed the senescence-associated secretory phenotype (SASP), which exacerbate inflammation, while inflammation can reciprocally promote cellular senescence. Quercetin (Que), recognized for its ROS-scavenging capabilities, holds the potential for anti-inflammatory and anti-senescent effects.

Comparative study of open elbow arthrolysis with and without hinge external fixation for the treatment of post-traumatic elbow stiffness.

Background: The present study aimed to compare the functional outcomes of hinged external fixators and non-external fixation in open elbow arthrolysis (OEA) for post-traumatic elbow stiffness (PTES) and to evaluate their applicability and limitations in patients with posttraumatic elbow stiffness.

Methods: The clinical data of patients with PTES treated with OEA at our hospital between March 2015 and June 2022 were retrospectively analyzed. The assessed variables were the operation time, intraoperative blood loss volume, duration of hospitalization, and treatment costs.

Are all cases of floating hip the same? Further understanding of floating hip.

Purpose: Floating hip is a severe high-energy injury. Femoral fracture is an essential component of floating hip. However, few studies have addressed the relationship between the femoral fracture pattern and floating hip injury.

Unveiling electron transfer and radical transformation pathways in coupled electrocatalysis and persulfate oxidation reactions for complex pollutant removal.

The degradation of multiple organic pollutants in wastewater via advanced oxidation processes might involve different radicals, of which the types and concentrations vary upon interacting with different pollutants. In this study, electrochemical activation of peroxymonosulfate (E/PMS) using advanced activated carbon cloth (ACC) as electrode was applied for simultaneous degradation of mixed pollutants, e.g.

Highly efficient removal of aqueous phosphate via iron-manganese fabricated biochar: Performance and mechanism.

Biochar (BC) has emerged as a potential solution to phosphate removal from wastewater primarily resulting from global overuse of fertilizers. Further modification by embedment of iron (Fe)-manganese (Mn) oxides on BC can enhance phosphate removal; however, the modification method serves as a vital factor underlying distinctive removal performances and mechanisms, which have yet been systematically examined. Herein, two Fe-Mn modified BC, Fe/MnBC (comprised of FeO and MnO) and Fe-MnBC (comprised of MnFeO), were comprehensively investigated for gaining insights into the unsolved perspectives.

Regio- and enantioselective nickel-alkyl catalyzed hydroalkylation of alkynes.

The migratory insertion of metal-hydride into alkene has allowed regioselective access to organometallics, readily participating in subsequent functionalization as one conventional pathway of hydroalkylation, whereas analogous process with feedstock alkyne is drastically less explored. Among few examples, the regioselectivity of metal-hydride insertion is mostly governed by electronic bias of alkynes. To alter the regioselectivity and drastically expand the intermediate pools that we can access, one aspirational design is through alternative nickel-alkyl insertion, providing opposite regioselectivity induced by steric demand.

Bone marrow mesenchymal stem cell-derived exosomal miR-221-3p promotes angiogenesis and wound healing in diabetes via the downregulation of forkhead box P1.

Aim: Impaired wound healing in patients with diabetes can develop into nonhealing ulcerations. Because bone marrow mesenchymal stem cells (BMSCs) exosomes can promote wound healing, this study aims to investigate the mechanism of BMSCs-isolated exosomal miR-221-3p in angiogenesis and diabetic wound healing.

Methods: To mimic diabetes in vitro, human umbilical vein endothelial cells (HUVECs) were subjected to high glucose (HG).

PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway.

Porcine circovirus type 2 (PCV2) infection can cause immunosuppressive diseases in pigs. Vascular endothelial cells (VECs), as the target cells for PCV2, play an important role in the immune response and inflammatory regulation. Endothelial IL-8, which is produced by porcine hip artery endothelial cells (PIECs) infected with PCV2, can inhibit the maturation of monocyte-derived dendritic cells (MoDCs).

The significance of m6A RNA methylation regulators in diagnosis and subtype classification of HBV-related hepatocellular carcinoma.

In recent years, abnormal m6A alteration in hepatocellular carcinoma (HCC) has been a focus on investigating the biological implications. In this study, our objective is to determine whether m6A modification contributes to the progression of HBV-related HCC. To achieve this, we employed a random forest model to screen top 8 characteristic m6A regulators from 19 candidate genes.

Identifying CTH and MAP1LC3B as ferroptosis biomarkers for prognostic indication in gastric cancer decoding.

Gastric cancer (GC), known for its high incidence and poor prognosis, urgently necessitates the identification of reliable prognostic biomarkers to enhance patient outcomes. We scrutinized data from 375 GC patients alongside 32 non-cancer controls, sourced from the TCGA database. A univariate Cox Proportional Hazards Model (COX) regression was employed to evaluate expressions of ferroptosis-related genes.

Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers.

The principal aim of this investigation is to identify pivotal biomarkers linked to the prognosis of osteosarcoma (OS) through the application of artificial intelligence (AI), with an ultimate goal to enhance prognostic prediction. Expression profiles from 88 OS cases and 396 normal samples were procured from accessible public databases. Prognostic models were established using univariate COX regression analysis and an array of AI methodologies including the XGB method, RF method, GLM method, SVM method, and LASSO regression analysis.

The effects of water, substrate, and intermediate adsorption on the photocatalytic decomposition of air pollutants over nano-TiO photocatalysts.

The photocatalytic performance of nano-TiO photocatalysts in air pollutant degradation greatly depends on the adsorption of water, substrates, and intermediates. Especially under excessive humidity, substrate concentration, and intermediate concentration, the competitive adsorption of water, substrates, and intermediates can seriously inhibit the photocatalytic performance. In the past few years, extensive studies have been performed to investigate the influence of humidity, substrate concentration, and intermediates on the photocatalytic performance of TiO, and significant advances have been made in the area.

Cholinergic Anti-inflammatory Pathway Attenuates Acute Liver Failure Through Inhibiting MAdCAM1/α4β7-mediated Gut-derived Proinflammatory Lymphocytes Accumulation.

Background & Aims: The function of cholinergic anti-inflammatory pathway (CAP) in acute liver failure (ALF) with inflammatory storm remains indefinite. The liver-gut axis has been proved to be crucial for liver homeostasis. Investigation about CAP regulation on liver-gut axis would enrich our understanding over cholinergic anti-inflammatory mechanism.

Rational design of animal-derived biochar composite for peroxymonosulfate activation: Understanding the mechanism of singlet oxygen-mediated degradation of sulfamethoxazole.

Animal-derived biochar are identified as a promising candidate for peroxymonosulfate (PMS) activation due to the abundant aromatics and oxygen-containing functional groups. The current investigation focuses on pig carcass-derived biochar (800-BA-PBC) by ball milling-assisted alkali activation. The results showed that 800-BA-PBC could effectively activate PMS and degraded 94.