The relationship between depression and academic burnout among undergraduate students majoring in eldercare services: a moderated mediation model.

Objectives: To explore the relationship between depression, self-efficacy, academic burnout, and social support among undergraduate students majoring in eldercare services in China.

Methods: A cross-sectional study was carried out among 957 students majoring in eldercare services across four provinces of China. The study employed questionnaires based on the Center for Epidemiological Studies Depression Scale, General Self-Efficacy Scale, Learning Burnout Scale, and Perceived Social Support Scale.

Associations of 24-hour movement guidelines adherence with social function and academic performance in youth with anxiety problems.

Purpose: Anxiety problems are prevalent among children and adolescents (being referred as youth), often impairing their social and academic functioning, while healthy lifestyles as outlined in 24-hour movement (24-HBM) guidelines may offer potential benefits, yet their specific associations remain understudied. This study is to explore the associations between 24-HMB adherence and social and academic functioning in U.S.

Correction: One independent or many independent? The relationship among self-construal, number of brand endorsers and brand attitudes.

[This corrects the article DOI: 10.3389/fpsyg.2024.

: A Review of Its Effects on Immune Organs.

() is a major pathogen in pigs and an emerging zoonotic agent which causes serious infections in humans. It is also an immunosuppressive pathogen that exerts detrimental effects on the thymus, spleen, lymph nodes, and macrophages, impairing their ability to perform their normal physiological functions. induces thymic atrophy, splenomegaly, and lymphadenectasis and triggers apoptosis in T cells and B cells, as well as pyroptosis in macrophages within immune organs.

Multifunctional hydrogel encapsulated with baicalin for full-layer regeneration of drug-resistant bacteria-infected wounds after radiotherapy.

The post-radiotherapy wounds are common in patients. The irradiation-induced reactive oxygen species (ROS) accumulation, nucleic acid damage, and inflammation greatly hinder wound healing. The irradiation-induced immunosuppression may further cause bacterial infection.

Characterizing community water systems exposed to wildfire in the Western U.S.

Wildfires have increased in size and severity and so has concern over how wildfires impact water security. The current literature suggests that wildfires may negatively impact surface water quality and community drinking water systems dependent on surface water as their drinking water source. Yet few studies consider the implications for the populations served by these downstream community drinking water systems.

A Luminescence Resonance Energy Transfer (LRET)-Based Nanoprobe for Ascorbic Acid Detection in Living Cells and Real Samples.

Ascorbic acid (AA) is a ubiquitous and essential, water-soluble electron donor in living organisms which must be obtained from the diet. AA deficiency is closely associated with the pathogenesis and/or progression of various diseases, including diabetes and neurodegenerative disorders affecting hippocampal neurogenesis and cognitive function. Thus, it is beneficial to monitor AA in living cells and real samples.

MiR-100-5p as a biomarker in hand-arm vibration disease: Mediating pathogenesis through angiogenesis suppression.

Hand-arm vibration disease (HAVD), also known as occupational Raynaud's disease, is an occupational disease that can cause injuries to the microcirculation in the fingertips, might leading to severe vascular and neurological damage. While HAVD has been defined as a peripheral vascular injury disorders, its comprehensive disease mechanisms-spanning molecular drivers, pathophysiological cascades, and clinically actionable biomarkers remain substantially unelucidated. Our study has used miRNA sequencing (miRNA-seq) to investigate the differential expression of miRNAs in HAVD patients compared to workers exposed to hand-transmitted vibration.

Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions for 2022-2040.

Objectives: Congenital birth defects (CBDs) rank among the top five causes of death in children under the age of five. Despite their significant impact, studies on the burden of CBDs in G20 countries remain limited. This study sought to examine the temporal trends in the disease burden and mortality rates of CBDs across G20 countries from 1990 to 2021, identify potential risk factors contributing to these trends, and project the disease burden and mortality rates for the period 2022-2040.

Visible Light-Induced C─C Bond Cleavage for the Construction of Ketone Using Molecular Oxygen.

The selective cleavage of carbon-carbon bonds by photocatalysis with the participation of oxygen for ketone synthesis and drug derivatization is reported. In this oxidation-based ketone formation reaction, molecular oxygen complexes with the substrate, which is subsequently photoexcited to generate a charge transfer (CT) state. This CT state facilitates energy transfer with molecular oxygen, producing singlet oxygen, which facilitates hydrogen atom process and promotes the subsequent cleavage of the carbon-carbon bond, ultimately leading to the formation of aryl ketone compounds.

Heterocycle-based dynamic covalent chemistry for dynamic functional materials.

Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic covalent chemistry can construct dynamic polymer networks, it rarely introduces other functions into polymers, which limits the development of dynamic functional materials. Herein, we develop heterocycle-based dynamic covalent chemistry and demonstrate the reversibility of the aza-Michael addition reaction between functional heterocycle dihydropyrimidin-2(1H)-thione and electron-deficient olefins.

Modifying loop regions in lipase from Caldibacillus thermoamylovorans for enhancing thermostability.

Lipases are widely used as green industrial catalysts. Lipases from thermophilic microorganisms are particularly valuable due to their expected thermostability. However, the natural catalytic abilities and tolerance to extreme conditions of most enzymes are often not directly suited to the demands of industrial applications.

Influence of Low Loadings of Cellulose Nanocrystals on the Simultaneously Enhanced Crystallization Rate, Mechanical Property, and Hydrophilicity of Biobased Poly(butylene 2,5-furandicarboxylate).

In this research, fully biobased composites consisting of poly(butylene 2,5-furandicarboxylate) (PBF) and cellulose nanocrystals (CNC) were successfully prepared through a common solution and casting method. The influence of CNC on the crystallization behavior, mechanical property, and hydrophilicity of PBF was systematically investigated. Under different crystallization processes, the crystallization of PBF was obviously promoted by CNC as a biobased nucleating agent.

Differences in soil Cd immobilization and blockage of rice Cd uptake by biochar derived from crop residue and bone - A 2-year field experiment.

Biochar is widely recognized as an effective amendment for soils contaminated with cadmium (Cd). However, the properties and elemental compositions of biochar derived from different feedstocks may significantly impact the transfer of Cd in the soil-rice system. This study conducted a two-year field trial in Cd-contaminated paddy soil.

A water-soluble Gd(III)-based fluorescence/-MR dual-modality probe for HS sensing.

We present a water-soluble fluorescence/MR dual-modality probe NBD[Gd] for HS detection. It showed 88.4% of fluorescence quenching and a 36% reduction in upon exposure to HS.

Iron-modified biochars and their aging reduce soil cadmium mobility and inhibit rice cadmium uptake by promoting soil iron redox cycling.

Iron (Fe) modified biochar has been widely used for cadmium (Cd) contaminated soil remediation. However, the accompanying anions introduced during the modification process potentially affect the behavior of Cd in soil. In this study, we investigated the distinct Cd immobilization mechanisms by Fe(SO) modified biochar (FSBC) and Fe(NO) modified biochar (FNBC) in a two-year pot experiment.

The Serum NLRP1 Level and Coronary Artery Calcification: From Association to Development of a Risk-Prediction Nomogram.

Background: To investigate the correlation between inflammasomes and coronary artery calcification (CAC), and develop and validating a nomogram for predicting the risk of CAC in patients with coronary artery disease (CAD).

Methods: A total of 626 patients with CAD at the Affiliated Hospital of Xuzhou Medical University were enrolled in this study. The patients were divided into the calcification group and the non-calcification group based on the assessment of coronary calcification.

The Relationship Between the Serum NLRP3 and Adiponectin Levels and Coronary Lesions in Patients with Unstable Angina with Type 2 Diabetes.

Objective: To investigate the Levels of Nucleotide-binding, leucine-rich repeat and pyrin domain-containing protein 3 (NLRP3) and Adiponectin (APN) and their relationship with the severity of coronary artery disease in patients with Unstable Angina (UA) and Type 2 Diabetes (T2D).

Methods: Two hundred and thirty-one patients with UA were diagnosed by CAG in the Department of Cardiology of the Affiliated Hospital of Xuzhou Medical University from July 2022 to May 2023 were included, and 74 healthy subjects were included as the control group. The levels of NLRP3 and APN in each group were detected by ELISA and the Gensini score in each patient according to the results of CAG.

Crystallization Behavior and Mechanical Property of Biodegradable Poly(butylene succinate--2-methyl succinate)/Cellulose Nanocrystals Composites.

Biodegradable poly(butylene succinate--2-methyl succinate) (PBSMS)/cellulose nanocrystals (CNC) composites were successfully prepared at low CNC loadings with the aims of improving crystallization and mechanical properties and extending the practical application of PBSMS. CNC is finely dispersed in the PBSMS matrix without obvious aggregations. The low content of CNC obviously promoted the crystallization behavior of PBSMS under different conditions.

Polyacrylamide/sodium alginate/sodium chloride photochromic hydrogel with high conductivity, anti-freezing property and fast response for information storage and electronic skin.

Photochromic hydrogels have promising prospects in areas such as wearable device, information encryption technology, optoelectronic display technology, and electronic skin. However, there are strict requirements for the properties of photochromic hydrogels in practical engineering applications, especially in some extreme application environments. The preparation of photochromic hydrogels with high transparency, high toughness, fast response, colour reversibility, excellent electrical conductivity, and anti-freezing property remains a challenge.

Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits.

Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they have not been fully characterized in East Asians (EAs). Here we identified mQTLs in whole blood from 3,523 Chinese individuals and replicated them in additional 1,858 Chinese individuals from two cohorts. Over 9% of mQTLs displayed specificity to EAs, facilitating the fine-mapping of EA-specific genetic associations, as shown for variants associated with height.

Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling.

Ensuring the homeostatic integrity of pulmonary artery endothelial cells (PAECs) is essential for combatting pulmonary arterial hypertension (PAH), as it equips the cells to withstand microenvironmental challenges. Spermidine (SPD), a potent facilitator of autophagy, has been identified as a significant contributor to PAECs function and survival. Despite SPD's observed benefits, a comprehensive understanding of its protective mechanisms has remained elusive.

Hydroxy-Safflower Yellow A Mitigates Vascular Remodeling in Rat Pulmonary Arterial Hypertension.

Purpose: The underlying causes of pulmonary arterial hypertension (PAH) often remain obscure. Addressing PAH with effective treatments presents a formidable challenge. Studies have shown that Hydroxysafflor yellow A (HSYA) has a potential role in PAH, While the mechanism underlies its protective role is still unclear.

One independent or many independent? The relationship among self-construal, number of brand endorsers, and brand attitudes.

Introduction: It was common for brands to use different numbers of endorsers in marketing practice. Nevertheless, research on brand endorsers' quantity has not yielded a uniform consensus. The previous research about brand endorsers mainly focuses on the appeal of endorsement, brand category, and endorser characteristics, paying less attention to the impact of cultural factors, particularly self-construal.

Microvascular abnormalities induced by hand-transmitted vibration reflects in finger systolic blood pressure: a cross-sectional study in China.

Objective: Local vibration can cause microcirculatory abnormalities such as blood stasis and symmetrical intermittent digital artery vasospasm. Finger SBP (FSBP) measurement is a potential way of assessing vascular components. This study aims to comprehensively investigate the relationship between the occurrence of the vibration-induced white finger (VWF) and changes in FSBP and then set the application value of FSBP measurements in the early diagnosis of VWF.