A water-soluble Gd(III)-based fluorescence/-MR dual-modality probe for HS sensing.

Chem Commun (Camb)

Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China.

Published: December 2024


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Article Abstract

We present a water-soluble fluorescence/MR dual-modality probe NBD[Gd] for HS detection. It showed 88.4% of fluorescence quenching and a 36% reduction in upon exposure to HS. It is readily uptaken by cells to sense the endogenous HS. Besides providing a bimodal HS imaging probe, our study also confirms the high HS level in CT26 cells and its functional consequence in promoting cell growth.

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http://dx.doi.org/10.1039/d4cc05042hDOI Listing

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