A clickable spherical nucleic acid probe for fluorescence and synchrotron radiation X-ray dual-modality imaging.

Chem Commun (Camb)

Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Key Laboratory of Micro Interface Physics and Detection, Chinese Academy of Sciences, Shanghai 201800, China.

Published: August 2025


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Article Abstract

In this study, we have developed a dual-mode probe based on click chemistry for spherical nucleic acids (SNAs), achieving extremely specific fluorescence imaging and synchrotron X-ray microscopy of neuronal cells.

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http://dx.doi.org/10.1039/d5cc02645hDOI Listing

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