A Longitudinal Case Study of Recurrent Pyostomatitis-Pyodermatitis Vegetans Followed by the Subsequent Development of Bullous Pemphigoid With the Presence of Anti-BP230 Autoantibodies Six Years Later.

Pyostomatitis vegetans (PSV) is a rare inflammatory condition that has been strongly associated with inflammatory bowel disease (IBD). Additionally, certain cases of PSV have been reported to co-occur with pyodermatitis vegetans (PDV), resulting in a distinct mucocutaneous manifestation. Herein, we present a clinical case of PSV in a 64-year-old male patient diagnosed with ulcerative colitis (UC).

Coix seed oil alleviates collagen-induced arthritis-associated muscle atrophy and functional decline by modulating gut microbiota dysbiosis.

Backgroud: The gut microbiota composition influences the pathogenesis of sarcopenia via the "gut microbiota-muscle axis", with probiotics serving as potential therapeutic agents. Coix seed oil (CSO), a bioactive component of Coix lacryma-jobi l., exhibit potent anti-inflammatory effects, however, its therapeutic role in rheumatoid sarcopenia (RS) and the underlying mechanisms of actions remain incompletely understood.

Laser modulation transfer phenomenon in a four-level heterodyne Rydberg atom system.

This paper investigates the transfer of probe or coupling light modulation interference to density matrix elements in a four-level heterodyne Rydberg system. By combining the density matrix dynamical equations with power spectral density (PSD) analysis, we derive analytical solutions to describe this phenomenon. Our results demonstrate that coherence in multi-level systems fundamentally enables this transfer mechanism, thereby increasing the system's noise floor and degrading microwave detection sensitivity.

Laser frequency stabilization method based on a ladder-type Rydberg atom electromagnetically induced transparency.

We established a theoretical model for the ladder-type EIT laser frequency stabilization method based on the analysis of the system response. By using the method of deriving the density matrix equations, we obtained the density matrix elements of the three-level system and subsequently derived the system's response function. Based on this, we revealed the complex interference mechanism of the modulated probe light in the atomic medium.

Correction: Dai et al. Comparison of Bone Bruise Pattern Epidemiology between Anterior Cruciate Ligament Rupture and Patellar Dislocation Patients-Implications of Injury Mechanism. 2023, , 1366.

In the original publication [...

Neural Implicit Representations for Multi-View Surface Reconstruction: A Survey.

Diverging from conventional explicit geometric representations, neural implicit representations utilize continuous function approximators to encode 3D surfaces through parametric formulations including signed distance fields (SDF), unsigned distance fields (UDF), occupancy fields (OF), and neural radiance fields (NeRF). These approaches demonstrate superior multi-view reconstruction fidelity by inherently supporting non-manifold geometries and complex topological variations, establishing themselves as foundational tools in 3D reconstruction. Neural implicit representations can be applied to a diverse array of reconstruction tasks, including object-level reconstruction, scene-level reconstruction, open-surface reconstruction and dynamic reconstruction.

High-sensitivity and low-harmonic microwave detection using Rydberg atoms based on a loop-level structure.

We propose and investigate a Rydberg atom sensor based on a loop-level structure, which utilizes the eigenfrequencies of the energy levels as a reference. This design eliminates the need for the local oscillator (LO) electric field required in the traditional superheterodyne structure while maintaining a linear relationship between the readout signal and the microwave (MW) electric field to be measured, along with exhibiting significantly lower harmonic distortion. For experimental validation, we implemented a cesium atomic system based on the loop five-level structure.

Synergistic treatment of acid mine drainage and urea wastewater based on urease-producing bacteria and sulfate-reducing bacteria: A strategy for waste resource utilization.

The acidic environment and lack of carbon sources in acid mine drainage (AMD) limit the effectiveness of sulfate-reducing bacteria (SRB) in its treatment. The use of urease-producing bacteria (UPB) to hydrolyze urea and drive SRB to treat AMD addresses these two key limitations. Based on the pollution characteristics of AMD from an abandoned sulfur iron mine in Southwest China, this study investigates the feasibility of the combined UPB-SRB treatment for simulated AMD, explores the synergistic mechanism, and evaluates the practical application of this synergy in the treatment of real AMD.

Three-dimensional lower limb kinematics and kinetics in femoroacetabular impingement syndrome (FAIS) patients with and without borderline developmental dysplasia of the hip (BDDH) during level walking.

Purpose: The impact of femoroacetabular impingement syndrome (FAIS) on gait has been reported; however, no studies have documented the effects of Borderline Developmental Dysplasia of the Hip (BDDH) combined with FAIS on gait. This study aimed to evaluate the kinematic and kinetic abnormalities of the lower extremities in patients with combined FAIS and BDDH during level walking.

Methods: A total of 42 participants were included, consisting of 14 patients with FAIS + BDDH, 14 with isolated FAIS and 14 healthy controls.

[Arthroscopic tissue engineering scaffold repair for cartilage injuries].

Objective: To standardize the operative procedure for tissue-engineered cartilage repair, by demonstrating surgical technique of arthroscopic implantation of decalcified cortex-cancellous bone scaffolds, and summarizing the surgical experience of the sports medicine department team at Peking University Third Hospital.

Methods: This article elaborates on surgical techniques and skills, focusing on the unabridged implantation technology and surgical procedure of decalcified cortex-cancellous bone scaffolds under arthroscopy: First, the patient was placed in the supine position. After anesthesia had been established, the surgeon established an arthroscope and explored the damaged area under the scope.

Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models.

The highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in aquatic birds since 1997, causing outbreaks in domestic poultry and occasional human infections worldwide. Recently, the cross-species transmission of a new reassortant variant from clade 2.3.

Biomechanical Determinants of Anterior Cruciate Ligament Stress in Individuals Post-ACL Reconstruction During Side-Cutting Movements.

This cross-sectional laboratory-based study investigates the stress characteristics of the anterior cruciate ligament (ACL) during side-cutting using a knee finite element (FE) model and identifies biomechanical factors influencing ACL stress. Kinematics and ground reaction forces (GRF) were collected from eight participants (age: 30.3 ± 5.

A Study on the Effects of Gluteal Muscle Activation on the Electromyography of Lower Limb Muscles in Young Male Patients With Patellofemoral Pain Syndrome.

Objective: Patellofemoral pain syndrome (PFPS) is a common knee issue, and hip joint function significantly affects knee health. Gluteus activation exercises are a promising treatment for PFPS. This study aims to investigate the impact of gluteal muscle activation exercises on the muscle involvement and movement patterns of young male patients with PFPS.

[Early efficacy of local tranexamic acid in reducing postoperative swelling in hallux valgus surgery].

Objective: To evaluate the early efficacy of local application of tranexamic acid on the osteotomy surface during hallux valgus surgery in reducing postoperative occult blood loss and thus postoperative swelling.

Methods: The data of 40 cases with hallux valgus osteotomy admitted to the Department of Foot and Ankle Surgery of Jishuitan Hospital from July 11, 2022 to October 8, 2022, including 5 males and 35 females were retrospectively analyzed. According to the inclusion and exclusion criteria, 32 cases were finally divided into 16 cases in the observation group (application of tranexamic acid) and 16 cases in the control group (no application of tranexamic acid).

The intelligent selenium-enriched tea withering control system.

This paper addresses the low level of intelligence in tea processing equipment in Enshi Prefecture by designing an intelligent withering control system based on the STMicroelectronics 32-bit Microcontroller (STM32). This control system can achieve real-time monitoring of the withering environment and automate the control of heating and ventilation dehumidification modules. By integrating IoT technology, relevant users can view the tea production process via mobile devices, enabling intelligent and remote production operations.

Vascular Smooth Muscle Cells Transdifferentiate into Chondrocyte-Like Cells and Facilitate Meniscal Fibrocartilage Regeneration.

The effective and translational strategy to regenerate knee meniscal fibrocartilage remained challenging. Herein, we first identified vascular smooth muscle cells (VSMCs) transdifferentiated into fibrochondrocytes and participated in spontaneous meniscal regeneration using smooth muscle cell lineage tracing transgenic mice meniscal defect model. Then, we identified low-intensity pulsed ultrasound (LIPUS) acoustic stimulus enhanced fibrochondrogenic transdifferentiation of VSMCs in vitro and in vivo.

Effects of High Pressure on In Vitro Bioavailability of Curcumin Loaded in Whey Protein Isolate/Carrageenan Composite Emulsion Gel: In Vitro Digestion Coupled with Cell Culture Model.

The oral bioavailability of curcumin is inherently low, which significantly limits its application in food systems. The objective of this study was to evaluate the impact of high-pressure processing on the stability and bioaccessibility of curcumin within an emulsion gel during simulated gastrointestinal transit and to assess its cellular uptake. Our findings suggest that increasing pressure levels and high κ-carrageenan concentrations can enhance the stability of the curcumin delivery system.

Short-Term Effects of Poly-L-Lactic Acid-b-Polyethylene Glycol Microsphere Injection on Different Adipose Tissue Types in Rats.

Background: Wrinkles and sagging, characteristics of aging, are associated with reductions in collagen and fat. Poly-L-lactic acid (PLLA) is widely used clinically as a tissue filler owing to its good biocompatibility and ability to improve wrinkles and signs of aging. Despite extensive studies of the mechanism of action of PLLA when used as a dermal filler, few studies have examined its effects on adipose tissue.

Effectiveness analysis of a pharmacist-led intervention for orthopedic perioperative use of antibiotics: a retrospective cohort study.

Background: Following the Chinese guidelines' recommendation to completely cancel routine cephalosporin skin tests, the choice of cephalosporin as surgical prophylactic medication was affected. This was due to the limited cognition of the predictive value of cephalosporin skin test or the desire to avoid medical disputes. The aim of this retrospective study was to evaluate whether the pharmacist-led perioperative antibiotic prophylaxis model could improve clinicians' medical behavior in choosing cephalosporin antibiotics for surgical prophylaxis.

[Biomechanics during cutting movement in individuals after anterior cruciate ligament reconstruction].

Objective: To evaluate knee biomechanics of patients about 12 months after anterior cruciate ligament (ACL) reconstruction during cutting and determine the abnormal biomechanical characteristics.

Methods: Sixteen males about 12 months after ACL reconstruction were recruited for this study. Three-dimensional kinematic and kinetic data were collected during cutting movement.

Preparation, Characterization and Formation Mechanism of High Pressure-Induced Whey Protein Isolate/κ-Carrageenan Composite Emulsion Gel Loaded with Curcumin.

In order to explore the formation mechanism of the emulsion gel induced by high pressure processing (HPP) and its encapsulation and protection of functional ingredients, a curcumin-loaded whey protein isolate (WPI)/κ-carrageenan (κ-CG) composite emulsion gel induced by HPP was prepared. The effect of pressure (400, 500 and 600 MPa), holding time (10, 20 and 30 min) and concentration of κ-CG (0.8%, 1.

Novel analgesic peptide derived from Cinobufacini injection suppressing inflammation and pain via ERK1/2/COX-2 pathway.

Inflammatory pain is a chronic pain caused by peripheral tissue inflammation, seriously impacting the patient's life quality. Cinobufacini injection, as a traditional Chinese medicine injection preparation, shows excellent efficacy in anti-inflammatory and analgesic treatment in patients with advanced tumors. In this study, a novel analgesic peptide CI5 with anti-inflammatory and analgesic bio-functions that naturally presents in Cinobufacini injection and its regulatory mechanism are reported.

Restoration of miR-299-3p promotes efferocytosis and ameliorates atherosclerosis via repressing CD47 in mice.

Atherosclerotic plaque formation is largely attributed to the impaired efferocytosis, which is known to be associated with the pathologic upregulation of cluster of differentiation 47 (CD47), a key antiphagocytic molecule. By gene expression omnibus (GEO) datasets analysis, we identified that four miRNAs are aberrantly downregulated in atherosclerosis, coronary artery disease, and obesity. Of them, hsa-miR-299-3p (miR-299-3p) was predicted to target the 3'UTR of human CD47 mRNA by bioinformatics analysis.