Transcriptome dynamics and allele-specific regulation underlie wheat heterosis at the anthesis and grain-filling stages.

Background: As wheat is a globally important staple crop, the molecular regulatory network underlying heterosis in wheat remains incompletely understood. The flag leaf is the primary source of photoassimilates during grain filling and plays a crucial role in yield formation. However, the genetic mechanisms linking flag leaf development to heterosis are still unclear.

Preliminary safety risk assessment of parabens in children's cosmetics sold in China.

Since adverse health outcomes of parabens added in children's cosmetics have been reported, it is important to investigate preliminary risk characteristic assessment of parabens preservatives in children's cosmetics. This study aimed to calculate exposure parameters using a combination experimental data and an exposure assessment tool to make safety assessment for parabens in children's cosmetics. The paraben concentration of different formulation types of 63 products of children's cosmetic products were measured by High Performance Liquid Chromatography.

Low-Profile Broadband Filtering Antennas for Vehicle-to-Vehicle Applications.

This paper proposes a compact, broadband, and low-profile filtering antenna designed for Sub-6 GHz communication. By applying characteristic mode analysis to the radiating elements, the operational mechanism of the antenna is clearly elucidated. The current cancellation among different radiating elements results in two radiation nulls in the primary radiation direction, effectively enhancing the filtering effect.

Global, regional, and national burden of periodontal diseases from 1990 to 2021 and predictions to 2040: an analysis of the global burden of disease study 2021.

Background: Periodontal diseases are one of the most prevalent oral diseases globally, with increasing incidence rates in recent years. This study aims to analyze the global burden and epidemiological trends of periodontal diseases from 1990 to 2021, and to forecast trends through 2040.

Methods: Data on incidence, prevalence, and disability-adjusted life-years (DALYs) of periodontal diseases were extracted from the Global Burden of Disease study 2021.

Erratum: Androgen Receptor Promotes Gastric Carcinogenesis via Upregulating Cell Cycle-Related Kinase Expression: Erratum.

[This corrects the article DOI: 10.7150/jca.34430.

Global, regional, and national burden of lip and oral cavity cancer and its attributable risk factors from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.

Background: Lip and oral cavity cancer is a significant global health concern, with increasing incidence rates in recent years. Understanding epidemiological trends and their associated risk factors is crucial for effective prevention and management.

Aim: This study aimed to analyze global, regional, and national trends in lip and oral cavity cancer incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2021 to assess key risk factors and sociodemographic influences to support clinical pharmacy interventions and improve patient outcomes.

Inhibiting oxidation of DHA algal oil by emulsifying with oat protein nanoparticles treated with dynamic high-pressure microfluidization.

Docosahexaenoic acid (DHA) algal oil is susceptible to oxidation, restricting its application in food industry. The DHA algal oil was converted to Pickering high internal phase emulsions (HIPEs) fabricated by dynamic high-pressure microfluidization (DHPM) modified oat protein isolates (MOPIs). DHPM treatment enhanced the amphiphilicity and interfacial activity of MOPIs, leading to the formation of HIPEs with regular polygonal network structures consisting of a dense and mechanically stable oil-water interface.

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm.

Background: Abdominal aortic aneurysm (AAA), characterized by the pathological dilation of the abdominal aorta, was associated with immune response and inflammation. However, the key genes involved in the occurrence and progression of AAA remains unclear.

Methods: We applied Weighted Gene Co-expression Network Analysis (WGCNA) and Support Vector Machine Recursive Feature Elimination (SVM-RFE) to screen for significant genes from the Gene Expression Omnibus (GEO) dataset.

Wet chemically produced nanomaterials for soft wearable biosensors.

Wearable biosensors are gaining significant attention for their ability to monitor vital health signs remotely, continuously, and non-invasively. Nanomaterials offer transformative potential for next-generation soft wearable sensors, enabling seamless skin integration with enhanced comfort and data accuracy. Wet chemistry provides a scalable, cost-effective approach to producing nanomaterials, transforming rigid sensors into soft, flexible, and stretchable devices for broader wearable applications.

Early-life feeding of arachidonic acid and docosahexaenoic acid beneficially modulated ileum and splenocyte oxylipins to support oral tolerance development in allergy-prone BALB/c mice.

Background: Early-life feeding of arachidonic acid (ARA)+docosahexaenoic acid (DHA) has been shown to promote immune changes associated with oral tolerance (OT). Oxylipins have been demonstrated to be modulated by diet and alter immune function.

Objective: To determine whether early-life feeding of ARA+DHA modulated the ileum and ovalbumin (OVA)-challenged splenocyte oxylipin profile in a way that is beneficial for OT development.

Prognostic Value of Pre-Treatment Diffusion Kurtosis Imaging for Progression-Free Survival Prediction in Advanced Nasopharyngeal Carcinoma.

Purpose: This study aimed to evaluate the value of diffusion kurtosis imaging (DKI) for prognostic value for long-term PFS in nasopharyngeal carcinoma (NPC).

Methods: A cohort of 295 NPC patients underwent pretreatment 3.0T MRI with DKI to derive mean kurtosis (MK), mean diffusion (MD), and apparent diffusion coefficient (ADC).

Two new polyketides with osteogenic activity from Talaromyces pinophilus WRH-1, an endophytic fungus residing in Perilla frutescens (L.) Britt.

Two azaphilones designated as acetosellins A and B (1-2) and one new coumarin (3), along with eight other known compounds (4-11), were isolated from an endophyte Talaromyces pinophilus WRH-1 of Perilla frutescens (L.) Britt. Their structures were elucidated through detailed interpretation of UV, NMR, and HR-ESI-MS data.

Edible rice starch films incorporated with curcumin nanoparticles exerting anti-microbial properties for strawberry preservation.

Pure starch film presents poor barrier properties and lacks anti-microbial properties. Herein, curcumin nanoparticles (cNPs) were prepared by the reassembly of food proteins and were utilized to reinforce the starch-based film. Herein, the reassembly of rice proteins and casein encapsulated curcumin upon pH adjustment to produce water-dispersible cNPs with a diameter of 140.

Double-helix singularity and vortex-antivortex annihilation in space-time helical pulses.

Topological structures reveal the hidden secrets and beauty in nature, such as the double helix in DNA, whilst, the manipulation of which in physical fields, especially in ultrafast structured light, draw booming attention. Here we introduce a new family of spatiotemporal light fields, i.e.

Sensing the Future of Thrombosis Management: Integrating Vessel-on-a-Chip Models, Advanced Biosensors, and AI-Driven Digital Twins.

Thrombotic events, such as strokes and deep vein thrombosis, remain a significant global health burden, with traditional diagnostic methods often failing to capture the complex, patient-specific nuances of thrombosis risk. This Perspective explores the revolutionary potential of microengineered vessel-on-chip platforms in thrombosis research and personalized medicine. We discuss the evolution from basic microfluidic channels to advanced 3D-printed, patient-specific models that accurately replicate complex vascular geometries, incorporating all elements of Virchow's triad.

Collaborative prediction and intelligent control of multiple pollutants emission from a large-scale waste incinerator.

Owing to the complexity of municipal solid waste (MSW), flue gas composition and operating conditions, it is challenging to predict pollutant emissions accurately and control them intelligently in the MSW incineration process. This study uses a 750 t/d large-scale grate-type MSW incinerator as the research object. Based on a long short-term memory (LSTM) model, collaborative prediction (co-prediction) of multiple pollutants (HCl, SO, NO, and PM) emissions from MSW incinerator flue gas was achieved.

Physiochemical properties of V-type cold water swelling tapioca starch prepared by ethanolic extrusion.

This study developed V-type cold-water swelling tapioca starch (VCSTS) through ethanolic extrusion from tapioca starch and examined the effects of various extrusion conditions on its physiochemical properties. The findings revealed that ethanolic extrusion transforms tapioca starch from A-type to V-type crystalline structure, giving VCSTS cold-water solubility/swelling capacity. XRD, FTIR, and SEM analyses confirmed that VCSTS produced under optimal conditions (extrusion temperature of 90 °C, 40 % ethanol solution, a starch-to-ethanol solution ratio of 1: 0.

Hybrid electromagnetic toroidal vortices.

The ubiquitous occurrence of toroidal vortices, or vortex rings, in fluid dynamics scenarios in nature has garnered notable attention in the scientific community, while their electromagnetic counterparts have only been proposed recently with two distinct manifestations: vector toroidal pulses and scalar phase toroidal vortices. Herein, we theoretically propose a form of electromagnetic toroidal vortex solutions that uniquely integrates both scalar and vector characteristics, challenging the prevailing notion of their mutual exclusivity. We also present an experimental generation of hybrid toroidal vortex pulses by a compact coaxial horn emitter augmented with a radial metasurface.

Merkel cell carcinoma in Taiwan: a subset is chronic arsenicism-related, and the Merkel cell polyomavirus-negative cases are pathologically distinct from virus-related cases with a poorer outcome.

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma of the skin, more frequent in the West than in the East. The pathogenesis is complex, with Merkel cell polyomavirus (MCPyV) and ultraviolet (UV) light being reported to play important roles. In this retrospective study of MCC cases from Taiwan, we analysed the prognostic significance of pathological features and the status of MCPyV and retinoblastoma (Rb) expression.

Efficient purification and identification of α-glucosidase inhibitory peptides from rice proteins by enzyme membrane reactors.

Bioactive peptides are growingly recognized with exceptional therapeutic abilities against numerous chronic diseases such as cardiovascular diseases. However, the advancement of peptide manufacturing is hindered by the trade-off between protein-peptide bioconversion and bioactivity retention. In this study, we demonstrate the efficient preparation of rice peptides using enzymatic membrane reactors (EMRs).

Characterization of the complete chloroplast genome of (Michx.) H.O.Yates, 1966 (Poaceae).

(Michx.) H.O.

Multiomics Analysis Reveals Therapeutic Targets for Chronic Kidney Disease With Sarcopenia.

Background: The presence of sarcopenia in patients with chronic kidney disease (CKD) is associated with poor prognosis. The mechanism underlying CKD-induced muscle wasting has not yet been fully explored. This study investigates the influence of renal secretions on muscles using multiomics sequencing.

Exploring the influence of "keeping consumers in suspense" in live streaming on consumer impulse buying behavior: A test of the mediating effects of consumer inner states.

Background: Live-streaming e-commerce has emerged as a dynamic shopping medium, engaging consumers through interactive and immersive experiences. "Keeping Consumers in Suspense" (KCIS), encompassing preview fuzziness, suspense setting, and delight creation, is widely used to drive engagement and impulse buying. Still, its impact on consumer inner states and behaviors remains underexplored.

Deciphering the biosynthetic pathway of triterpene saponins in Prunella vulgaris.

The traditional Chinese medicinal plant Prunella vulgaris contains numerous triterpene saponin metabolites, notably ursolic and oleanolic acid saponins, which have significant pharmacological values. Despite their importance, the genes responsible for synthesizing these triterpene saponins in P. vulgaris remain unidentified.