Utilization of steelwork off-gases through methanol synthesis: Sulfur-induced dynamic migration of ZnO over industrial Cu/ZnO/AlO catalyst and the poisoning mechanism.

The reduction of carbon emissions in the steel industry is a significant challenge, and utilizing CO from carbon intensive steel industry off-gases for methanol production is a promising strategy for decarbonization. However, steelwork off-gases typically contain various impurities, including HS, which can deactivate commercial methanol synthesis catalysts, Cu/ZnO/AlO (CZA). Reverse water-gas shift (RWGS) reaction is the predominant side reaction in CO hydrogenation to methanol which can occur at ambient pressure, enabling the decouple of RWGS from methanol production at high pressure.

Neural correlates of aggression in schizophrenia: An event-related potential study using the competitive reaction time task.

Background: The neural mechanisms underlying aggressive behavior in schizophrenia (SCZ) remain poorly understood. To date, no studies have reported on the event-related potential (ERP) characteristics of aggression in SCZ using the competitive reaction time task (CRTT). Further investigation into the ERP correlates of aggression in SCZ would provide valuable insights into the neural processes involved.

Tobacco exposure and risk of spontaneous abortion, a dose-dependent association: A systematic review and meta-analysis.

Introduction: This systematic review and meta-analysis aimed to quantify the dose-dependent association between tobacco exposure (active and passive smoking) and the risk of spontaneous abortion (SA), incorporating subgroup analyses to evaluate the influence of study design.

Methods: Following PRISMA guidelines, we conducted a systematic search of PubMed, Embase, and Cochrane Library databases for English-language observational studies published between 1991 and 2023. Studies were included if they reported on the association between active or passive tobacco exposure during pregnancy and SA risk (defined as pregnancy loss before 20 weeks of gestation).

miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis.

ObjectiveTo investigate the novel role of miR-708-5p in osteoarthritis (OA) and its potential as a therapeutic target through regulation of NOX4/NF-κB signaling.MethodsExpression levels of miR-708-5p were analyzed in OA cartilage using GEO datasets and validated in interleukin (IL)-1β-treated primary human chondrocytes. Gain- and loss-of-function experiments were performed using miR-708-5p mimics and inhibitors to evaluate its effects on inflammation, extracellular matrix metabolism, apoptosis, and oxidative stress.

Investigation on the Intrinsic Phonon Properties of CrPS: A Combined Raman Spectroscopy and First-Principles Calculations Study.

Compared to other vdW-layered magnetic semiconductors, research on the intrinsic phonon properties of antiferromagnetic CrPS is in its infancy, and elucidating these properties is crucial for unlocking its emerging applications. In this work, we combined Raman spectroscopy and first-principles calculations to thoroughly investigate the lattice vibrations of CrPS, uncovering its anisotropic phonon symmetry and phonon-phonon interactions. Angle-resolved polarized Raman spectroscopy was used to determine the orientation of the anisotropic CrPS crystal.

Reintroduction training is instrumental in restoring the oral microbiota of giant pandas from "captivity" to "wildness".

Reintroduction programs aim to restore wild populations, yet success is challenged by host microbiome adaptation to natural environments. Here, we characterized the oral microbiota of giant pandas undergoing pre-release training, comparing them to captive and wild conspecifics, to assess training-induced microbial shifts. We found that after one year of reintroduction training, multi-generational captive giant pandas exhibited increased oral microbiome diversity, with community structure, composition, and predicted functions converging toward wild-type profiles.

The Incidence and Trends of Yellow Fever from 1990 to 2021 in Major Endemic Regions: A Systematic Analysis Based on the 2021 Global Burden of Disease Study.

As a re-emerging disease, the worldwide burden and trends of yellow fever (YF) remain inadequately quantified. This study aims to assess the incidence of YF both globally and in major endemic regions from 1990 to 2021. Utilizing data from the Global Burden of Disease (GBD) database, we evaluated the burden of YF.

Development of a Radiomic-clinical Nomogram for Prediction of Survival in Patients with Nasal Extranodal Natural Killer/T-cell Lymphoma.

Introduction: An accurate and reliable prognostic model for Nasal Extranodal Natural Killer/T-cell Lymphoma (ENKTL) is critical for survival outcomes and personalized therapy. Currently, there is no Magnetic Resonance Imaging (MRI)- based radiomics analysis in the prognosis model for nasal ENKTL patients.

Objective: We aim to explore the value of MRI-based radiomics signature in the prognosis of patients with nasal ENKTL.

A robust DNA walker for simplified, rapid, and sensitive detection of HBV DNA in blood.

Although preventive vaccine is available, HBV infection continues to be a global health challenge, especially in rapid and accurate screening in resource-limited regions due to underdeveloped infrastructures. In this study, we developed a self-powered DNA walker system integrating AuNPs and DNAzyme for direct detection of HBV DNA in blood. In the presence of HBV DNA, this DNA walker was activated to start autonomous and rapid movement on AuNPs driven by DNAzyme, and the amplified fluorescent signals were generated and detected.

Fenaminosulf Promotes Growth and Gall Formation in Through Modulation of Physiological and Molecular Pathways.

(Jiaobai) is an economically important aquatic crop characterized by unique gall formation through interaction with the smut fungus . Understanding factors influencing this interaction is crucial for cultivation. This study investigates the non-target effects of the fungicide Fenaminosulf (FM) on 's growth, physiology, and underlying molecular pathways.

Hepatopathy-thrombocytopenia syndrome and disease relapse in pediatric wilms tumor: A 20-year retrospective analysis in a single center.

Background: Wilms tumor (WT) is the most common renal malignancy in children. With current treatments, the 5-year overall survival (OS) rate for children with WT is approximately 90 %. However, nearly 15 % of patients experience disease recurrence.

Real-world treatment patterns and outcomes among patients with HER2-positive unresectable or metastatic breast cancer in China.

Background: Breast cancer is now the most commonly diagnosed cancer in the world and the leading cause of cancer mortality in women worldwide. In past few years, anti- human epidermal growth factor receptor-2 (HER2) therapy for metastatic breast cancer (mBC) has rapidly altered in China. This study aimed to describe treatment patterns and outcomes in patients with HER2-positive unresectable or metastatic breast cancer in the real-world setting.

Effect of Spinetoram Stress on Midgut Detoxification Enzyme and Gene Expression of Fabricius.

This study aimed to evaluate the impact of Spinetoram (SPI) on the midgut of Fabricius pupae, emphasizing detoxifying enzyme activity, gene expression, and morphological alterations. Pupae were subjected to SPI at LC and LC concentrations, and the midgut was evaluated using morphological assessment, detoxifying enzyme assays, and transcriptome analysis utilizing gene ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment. Transcriptome analysis revealed 32 differentially expressed genes (DEGs) that were common to both the LC vs.

Small Fluorinated Aromatic Molecule-Based Radiofrequency Identification Tags Enabled by Stepwise Tuning of Nuclear Shielding.

In the Internet of Things (IoT) network, radiofrequency identification (RFID) is a key enabler for wireless communication, facilitating real-time monitoring and control. A primary goal of enhancing IoT infrastructure is the development of versatile RFID tags that are of compact size, high capacity, and robust security with seamless read-write operations. Here, we report a fluorine-19 nuclear magnetic resonance (F NMR)-based molecular encoding strategy using a fluorinated aromatics (FArs) library, termed "FArsEER" (fluorinated aromatics-empowered encoding and reading), to generate small molecule-based ID tags (Farcodes).

Chromosome-level genome assembly of the predatory flower bug Orius strigicollis.

Predatory insects serve as important biological control agents in ecosystems by efficiently reducing pest populations. Orius strigicollis is a highly effective beneficial predator in cultivated fields in China. It is widely used as a biological control agent against many pests, including thrips, aphids, and spider mites.

DNAJC5 facilitates the proliferation and migration of lung adenocarcinoma cells by augmenting EGFR trafficking.

Lung adenocarcinoma (LUAD) is a highly prevalent and lethal malignant tumor, with the aberrantly activated EGFR signaling pathway playing a crucial role in its development. However, resistance to tyrosine-kinase inhibitors (TKIs) targeting EGFR significantly limits the efficacy of LUAD clinical therapy. Therefore, it is imperative to identify novel therapeutic targets and elucidate the regulatory mechanisms of EGFR for improving LUAD treatment outcomes.

High Genetic Variability of Hepatitis B Virus in Blood Donors With Surface Antigen Positive But DNA Negative in Southern China.

In our previous studies, 45.2% of donations with HBV HBsAg reactive (+) by ELISA but negative (-) by NAT were confirmed to have HBV infections in Shenzhen Blood Center, China. However, the serological and molecular characteristics of this type of HBV infection remain unclear, and several donations with indeterminate results require further investigation.

Research trends and hotspots of osteoporosis and intestinal microbiota: A bibliometric analysis.

Background: Osteoporosis (OP) is the second most detrimental chronic disease, and thus novel diagnostic and therapeutic approaches are needed. In recent years, there has been an increased emphasis on the utilization of gut microbiota (GM) in the context of OP. However, a comprehensive bibliometric analysis on this subject is currently lacking.

A new perspective: Acyl-CoA synthetase long-chain family member 4 inhibits ubiquitin-specific protease 7-induced epithelial ovarian cancer progression by inducing ferroptosis and M1 macrophage polarization.

Objective: Epithelial ovarian cancer (EOC) is the most common and lethal type of ovarian cancer, and the cross-talk between tumor cell ferroptosis and macrophages is essential to cancer progression. This study aims to investigate the roles of ubiquitin-specific protease 7 (USP7) and acyl-CoA synthetase long-chain family member 4 (ACSL4) in the pathogenesis of EOC.

Material And Methods: The expression patterns of USP7 and ACSL4 in EOC cell lines were first determined by quantitative reverse transcription polymerase chain reaction (qRT-PCR) and Western blot.

Analysis of Blood Microbiome From People Living With HIV and Donors by 16S rRNA Metagenomic Sequencing.

Utilize 16S rRNA sequencing technology to characterize bacterial species susceptible to people living with HIV (PLWH) across different stages. This mapping aims to establish a foundational framework for preventing secondary HIV infections, prolonging patient survival, enhancing quality of life, and advancing the diagnosis, treatment, and research of bacterial co-infections. In this study, we classified the participants into three groups: The blood of donors living with HIV (DI group), AIDS patients who have received ART treatment (PI group), and healthy blood donors as the control group (DH group).

Clinical characteristics and risk factors for readmission after deep anterior lamellar keratoplasty: a nationwide, cross-sectional, multicenter study.

Background: To assess the incidence, cause and risk factors for unplanned readmission within 90 days after deep anterior lamellar keratoplasty (DALK).

Methods: A multicentre cross-sectional study of 3603 eyes of 3588 patients after keratoplasty between January 1st, 2019, and September 30th, 2021 in 16 hospitals across China was performed. The demographic and clinical features between patients after DALK with 90-day unplanned readmission and those who did not have been compared.

Global Burden and Trends of Acute Hepatitis C From 1990 to 2021: An Analysis Based on the 2021 Global Burden of Disease Study.

Acute hepatitis C (AHC) represents a considerable challenge to global public health, although direct-acting antiviral (DAA) therapy has substantially improved therapeutic outcomes for hepatitis C virus infection. Data were exclusively obtained from the 2021 Global Burden of Disease (GBD) study, which examined trends in the burden of AHC in terms of incidence, mortality and disability-adjusted life years (DALYs) across 204 countries and territories globally from 2009 to 2021. In 2021, there were 7,009,910.

La/Fe-Bimetallic-Modified Red Brick Powder for Phosphate Removal from Wastewater: Characterization, Adsorption, and Mechanism.

The use of construction waste red brick powder (RBP) to prepare adsorbents for phosphate removal from wastewater represents a promising technology with substantial research potential. This study investigates the preparation of La-based magnetic red brick powder (La-Fe-RBP) via bimetallic modification to enhance its adsorption performance. The key characteristics, adsorption process, adsorption mechanism, and practical applications of the modified adsorbent were analyzed.