Genetic characteristics and risk factors of extended-spectrum β-lactamase-producing in Chinese intensive care unit: a prospective molecular epidemiology study.

In this 4-month-long prospective observational study, we explored the colonization rate of extended-spectrum β-lactamase-producing (ESBL-EC) in the patient and ward environment of an intensive care unit (ICU). Additionally, we evaluated the risk factors for colonization and analyzed genomic characteristics and modes of transmission of isolates. Clinical samples were collected from patients and the environment to isolate and screen strains.

Co-design of the Intelligent HOme-based Palliative care for End-of-life system: A development and feasibility study.

ObjectiveThis study aimed to develop the Intelligent HOme-based Palliative care for End-of-life (I-HOPE) system, a WeChat mini-program designed to provide home-based palliative care (HBPC), including education, interaction, and social resource access for users.MethodsA mixed-method approach was employed to ensure a comprehensive exploration of user needs, system design, and evaluation. This approach integrated qualitative and quantitative methods, rapid prototyping, expert consultations, and co-design methodologies informed by social ecological theory.

Effect of hydroxypropyl cellulose on vitrification of sheep embryos.

Vitrification is a conventional and mature method for embryo cryo-preservation, but ice crystals formed during the vitrification process can damage embryos. HPC has the property of forming a high-viscosity gel under low-temperature conditions, so it can be added to vitrification solutions to investigate whether it improves the negative impact of vitrification on embryos. The results showed that the addition of HPC (50 μg/ml) to the vitrification solution significantly increased the post-warming survival rate of sheep morula embryos.

Enhancement of dewatering performance and effective degradation of petroleum hydrocarbons in biological oily sludge using atmospheric pressure plasma jet.

The presence of petroleum hydrocarbon components (PHCs) in biological oily sludge increases the toxicity of the sludge and makes dewatering even more difficult. In this study, an atmospheric pressure plasma jet (APPJ) technology was used for treating biological oily sludge. The results showed that under specific conditions-a sludge/water ratio of 1:100, a discharge power of 440 W, and a 60-min treatment-the degradation rate of PHCs reached 36.

Impact of early high protein intake in critically ill patients: a randomized controlled trial.

Background: Conflicting findings regarding the impact of High protein intake during the early phase in critically ill patients have been reported. Therefore, we aimed to assess the influence of higher early protein intake on the prognosis of critically ill patients.

Methods: This randomized controlled trial involved 173 critically ill patients who stayed in the Intensive Care Unit/Emergency ICU (ICU/EICU) for at least 7 days.

Mechanisms of nanoscale zero-valent iron mediating aerobic denitrification in Pseudomonas stutzeri by promoting electron transfer and gene expression.

Aerobic denitrification and its mechanism by P. stutzeri was investigated in the presence of nanoscale zero-valent iron (nZVI). The removal of nitrate and ammonia was accelerated and the nitrite nitrogen accumulation was reduced by nZVI.

Exploring the needs and coping strategies of family caregivers taking care of dying patients at home: a field study.

Background: Most Chinese patients chose to die at home, therefore there is a reliance on the family caregivers to be involved in their palliative care. The needs and coping strategies of family caregivers in home-based palliative care are rooted in culture. Little is known about the needs and coping strategies of family caregivers taking care of dying patients at home.

What drives the growth of china's mariculture production? An empirical analysis of its coastal regions from 1983 to 2019.

China's mariculture (i.e., seafood farming in the ocean) production has grown rapidly.

Activation of peroxymonosulfate by biochar-supported FeO derived from oily sludge to enhance the oxidative degradation of tetracycline hydrochloride.

Carbon materials used for catalysis in advanced oxidation processes tend to be obtained from cheap and readily available raw materials. We constructed a carbon material, OSC@FeO, by loading FeO onto the pyrolyzed hazardous waste oily sludge. OSC@FeO was then used to activate peroxymonosulfate (PMS) for the removal of tetracycline hydrochloride (TTCH) from water.

Fluorogen-Functionalized Mesoporous Silica Hybrid Sensing Materials: Applications in Cu Detection.

Since Cu ions play a pivotal role in both ecosystems and human health, the development of a rapid and sensitive method for Cu detection holds significant importance. Fluorescent mesoporous silica materials (FMSMs) have garnered considerable attention in the realm of chemical sensing, biosensing, and bioimaging due to their distinctive structure and easily functionalized surfaces. As a result, numerous Cu sensors based on FMSMs have been devised and extensively applied in environmental and biological Cu detection over the past few decades.

Synergetic effect of photocatalytic oxidation plus catalytic oxidation on the performance of coconut shell fiber biochar decorated α-MnO under visible light towards BPA degradation.

Photocatalytic technology is regarded as a promising approach for fast degradation of refractory organic pollutant in water. However, the performance of the photocatalyst can be restricted by the variation of water matrix conditions. Herein, coconut shell fiber was pyrolyzed to biochar (CSB800) and incorporated with α-MnO to degrade bisphenol A (BPA) in water under visible light irradiation.

Microplastic pollution in water environment of typical nature reserves and scenery districts in southern China.

Microplastics were frequently detected in the ocean, freshwater environment and wastewater treatment plants. This study aims to fill up the knowledge gap of microplastic distribution in nature reserves and scenery districts. Microplastic samples were collected, the distribution characteristics were analyzed with a stereoscopic microscope and a Fourier transform infrared spectrometer, and the ecological risks of microplastic pollution were calculated.

Occurrence and removal of antibiotics from aquaculture wastewater by solar-driven Fe(VI)/oxone process.

In this study, the occurrence and removal of ten selected antibiotics from aquaculture wastewater by the process solar + Fe(VI)+oxone were investigated. The detection levels of the antibiotics in the aquaculture wastewater samples were at ng/L. The degradation of the selected antibiotics under the process solar + Fe(VI)+oxone followed pseudo-first-order kinetics.

Adverse effects of silver nanoparticles on aquatic plants and zooplankton: A review.

With the rapid development of nanotechnology in the past decades, AgNPs are widely used in various fields and have become one of the most widely used nanomaterials, which leads to the inevitable release of AgNPs to the aquatic environment through various pathways. It is important to understand the effects of AgNPs on aquatic plants and zooplankton, which are widely distributed and diverse, and are important components of the aquatic biota. This paper reviews the effects of AgNPs on aquatic plants and zooplankton at the individual, cellular and molecular levels.

Wood induced preparation of FeC decorated biochar for peroxymonosulfate activation towards bisphenol a degradation with low ion leaching.

Heterogeneous iron/persulfate system suffers from the problems of high ion leaching, severe catalyst surface corrosion and low performance stability. Herein, a series of iron compound incorporated N doped biochar composite catalysts were prepared from pyrolyzing wood powder and ferric ferrocyanide mixture, which were used for bisphenol A (BPA) degradation in water through peroxymonosulfate (PMS) activation. It was found that the reducing gases released from wood powder at different pyrolysis temperature significantly affected the crystalline phase of the iron compound in the catalyst, in which pure phase iron carbide (FeC) decorated N doped biochar was obtained at pyrolysis temperature of 600 °C or higher.

Bereavement and Professional Competencies: Exploring the Personal Experience of Death Among Nursing Students - A Qualitative Study.

To explore the death experiences of nursing students in their personal lives. This study employed a qualitative descriptive design using the semi-structured interview approach. A purposive sampling method was used to recruit 24 nursing students from September 2020 to July 2022.

Epidemiology and Genetic Characteristics of Carbapenem-Resistant Escherichia coli in Chinese Intensive Care Unit Analyzed by Whole-Genome Sequencing: a Prospective Observational Study.

This 4-month-long prospective observational study investigated the epidemiological characteristics, genetic composition, transmission pattern, and infection control of carbapenem-resistant Escherichia coli (CREC) colonization in patients at an intensive care unit (ICU) in China. Phenotypic confirmation testing was performed on nonduplicated isolates from patients and their environments. Whole-genome sequencing was performed for all E.

The efficacy of modified HuangLian JieDu decoction for early enteral nutrition in patients with sepsis: A randomized controlled study.

Objective: This study aimed to evaluate the efficacy of modified HuangLian JieDu decoction (MHLJDD) as a supplementary medication for early enteral nutrition in septic patients.

Methods: This study was designed as a randomized controlled preliminary study. Septic patients were randomly divided into control (treated with the base treatment) and intervention (co-treated with MHLJDD and the base treatment) groups.

High performance flexible and antibacterial strain sensor based on silver‑carbon nanotubes coated cellulose/polyurethane nanofibrous membrane: Cellulose as reinforcing polymer blend and polydopamine as compatibilizer.

In this study, ethyl cellulose was used as the second-phase polymer blended with polyurethane to make nanofibrous membrane as antibacterial strain sensor. The results indicated that ethyl cellulose could regulate the morphology of polyurethane through strong hydrogen bonding, which observably enhanced the nanofiber uniformity of polyurethane. Furthermore, rigid cellulose also remarkably improved the mechanical strength and thermal stability of the nanofibrous membrane.

Toxicity of nanoplastics to aquatic organisms: Genotoxicity, cytotoxicity, individual level and beyond individual level.

Due to the small size, high mobility and large surface area, nanoplastics (NPs) showed high potential risks to aquatic organisms. This paper reviews the toxicity of NPs to aquatic organism at various trophic levels including bacteria, plankton (algae), zooplankton, benthos, and nekton (fish). The effects at individual level caused by NPs were explained and proved by cytotoxicity and genotoxicity, and the toxicity of NPs beyond individual level was also illustrated.

Construction of flexible fiber-shaped boron-doped diamond film and its supercapacitor application.

Flexible fiber-shaped supercapacitors (FSSCs) are promising candidates as electrode materials for the development of deformable electronic devices. Although tremendous efforts have been focused on the preparation of flexible electrode materials, traditional FSSCs materials face problems of inferior stability and complicated processes. Boron-doped diamond (BDD) holds promise as a FSSC electrode, owing to its well-established preparation process, strong acid and alkali corrosion resistance, environmentally and skin-friendly characteristics.

TLR2 agonist promotes myeloid-derived suppressor cell polarization via Runx1 in hepatocellular carcinoma.

Myeloid-derived suppressor cells (MDSCs) play a critical role in maintaining the tumor immune microenvironment; thus, the promotion of MDSC polarization will improve immunotherapies for cancers. However, the mechanisms involved in controlling MDSC polarization in hepatocellular carcinoma remain largely unclear. In this study, we found that injection of Pam3CSK4 attenuated the process of tumor growth, along with reduction of MDSC and recovery of T cell function.

Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis.

Liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin) plays an important regulatory role in a variety of diseases, including tumors. However, the underlying mechanism of LSECtin in gastric cancer (GC) remains largely unknown. In our research, LSECtin promoted the adhesion and invasion of GC cells, and was involved in lymphatic metastasis of GC cells.

Sulfide-modified zero-valent iron activated periodate for sulfadiazine removal: Performance and dominant routine of reactive species production.

In this work, sulfide-modified zero-valent iron (S-Fe) was used to activate periodate (IO, PI) for sulfadiazine (SDZ) removal. 60 μM SDZ could be completely removed within only 1 min by S-Fe/PI process. Compared with other oxidants including HO, peroxymonosulfate (PMS), peroxydisulfate (PDS), S-Fe activated PI exhibited better performance for SDZ removal but with lower Fe leaching.

Development of a Colloidal Gold Immunochromatographic Strip for Rapid Detection of Cyfra 21-1 in Lymph Node Metastasis of Thyroid Cancer.

Thyroid cancer is the most common endocrine tumor, and the rate of early lymph node metastasis may be as high as 60%. Currently, detection of lymph node metastasis of thyroid cancer during surgery is limited and time-consuming. Elevated levels of Cyfra 21-1, the proteolytic portion of cytokeratin, are associated with the metastasis and progression of thyroid cancer and are an effective biomarker for the prognosis and diagnosis of thyroid cancer.