The correlation between airborne pollen and asthma in children: a systematic review and meta-analysis.

Background: Childhood asthma is a prevalent chronic respiratory disease globally. Airborne pollen is a known environmental trigger, but the impact of different pollen types on pediatric asthma remains unclear. Seasonal and geographic pollen variations, influenced by climate change, may affect asthma patterns.

The Effect of Molding Temperature on the Mechanical and Tribological Properties of Modified Phenolic Resin-Based Friction Materials.

In order to investigate the influence of molding temperature on the mechanical and tribological properties of modified phenolic resin-based friction materials, six kinds of friction materials (FMs) with different molding temperatures were prepared by a hot-pressing process using melamine-modified phenolic resin (MPR) and boron-modified phenolic resin (BPR) as binders. The experimental results show that the density change of the friction materials is very small. The hardness, compressive strength, and compressive modulus decrease with the increase of molding temperature, and the impact strength decreases with the increase of molding temperature.

Mussel-Inspired Hemostatic Hydrogel Adhesive Formulated from a Gelatin-Oxidized Dextrin Double Network.

Hydrogels are recognized for their excellent biocompatibility and biodegradability, making them promising candidates for hemostatic materials, especially in cases of intra-abdominal bleeding or injury to vital organs. In this study, a mussel-inspired adhesive hemostatic hydrogel, GMOD, is developed, which features injectability, outstanding biocompatibility, and biodegradability. The hydrogel is synthesized through Schiff base crosslinking of oxidized dextran and gelatin, enhanced with dopamine to form a robust double network structure.

Construction of a prognostic risk model for clear cell renal cell carcinomas based on centrosome amplification-related genes.

Clear cell renal cell carcinoma (ccRCC) is the urological malignancy with the highest incidence, centrosome amplification-associated genes (CARGs) have been suggested to be associated with carcinogenesis, but their roles in ccRCC are still incompletely understood. This study utilizes bioinformatics to explore the role of CARGs in the pathogenesis of ccRCC and to establish a prognostic model for ccRCC related to CARGs. Based on publicly available ccRCC datasets, 2312 differentially expressed genes (DEGs) were identified (control vs.

Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway.

Background: The Food and Drug Administration has approved the Serine/threonine-protein kinase B-raf (BRAF) inhibitor and Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitor combo as the first-line treatment for individuals with metastatic melanoma, although the majority of these patients exhibit primary or secondary drug resistance in the clinic. Dihydrotanshinone I (DHT) is a lipophilic compound extracted from the root of Salvia miltiorrhiza that has been linked to multiple antitumor activities. In this study, we investigated the effect of dihydrotanshinone I on the MAPK pathway inhibitor resistance of BRAF mutant malignant melanoma.

Modeling and chewing parameters calibration of Euryale ferox based on discrete element method.

Euryale ferox was chosen for this study to examine its mechanical properties during chewing. Experiments and the discrete element method were used to conduct the study. Initially, the intrinsic and contact parameters of E.

Exploring the association between atmospheric pollutants and preterm birth risk in a river valley city.

Objective: To investigate the association between exposure to atmospheric pollutants and preterm birth in a river valley-type city and its critical exposure windows.

Methods: A retrospective cohort study was used to collect data from the medical records of preterm and full-term deliveries in two hospitals in urban areas of a typical river valley-type city from January 2018 to December 2019. A total of 7,288 cases were included in the study with general information such as pregnancy times, the number of cesarean sections, occupation, season of conception and regularity of the menstrual cycle.

Janus structural TaON/Graphene-like carbon dual-supported Pt electrocatalyst enables efficient oxygen reduction reaction.

Developing carbon-supported Pt-based electrocatalysts with high activity and long-durability for the oxygen reduction reaction (ORR) is an enormous challenge for their commercial applications due to the corrosion of carbon supports in acid/alkaline solution at high potential. In this work, a Janus structural TaON/graphene-like carbon (GLC) was synthesized via an in-situ molecular selfassembly strategy, which was used as a dual-carrier for platinum (Pt). The as-obtained Pt/TaON/GLC presents high half-wave potential (0.

Relationship between air pollutants and spontaneous abortion in a coal resource valley city: a retrospective cohort study.

Objective: Pollutants in the atmosphere have been linked to poor pregnancy outcomes in women. However, such investigations are scarce in metropolitan northern China. The major exposure window of air pollution affecting pregnant women is also unknown.

Discovery of unique CYP716C oxidase involved in pentacyclic triterpene biosynthesis from Camptotheca acuminata.

Dozens of triterpenes have been isolated from Camptotheca acuminata, however, triterpene metabolism in this plant remains poorly understood. The common C28 carboxy located in the oleanane-type and ursane-type triterpenes indicates the existence of a functionally active triterpene, C28 oxidase, in this plant. Thorough mining and screening of the CYP716 genes were initiated using the multi-omics database for C.

Weakened Crystalline SnNb O for Enhanced Performance in Photocatalytic H Production and CO Reduction.

Low crystalline photocatalysts with unsaturated active sites, such as oxygen vacancy (O ), is reported to exhibit enhanced adsorption and activation of oxygen-containing small molecules, such as H O and CO , thus boosting the activity in photocatalytic H evolution and CO reduction. However, numerous low-crystalline photocatalysts show unsatisfactory stability due to the easily repaired surface O . Herein, three SnNb O with different crystallinity were prepared by hydrothermal approach with similar precursors.

Hexokinase1: A glucose sensor involved in drought stress response and sugar metabolism depending on its kinase activity in strawberry.

Hexokinase1 (HXK1) is a bifunctional enzyme that plays indispensable roles in plant growth, nitrogen utilization, and stress resistance. However, information on the HXK family members of strawberries and their functions in glucose sensing and metabolic regulation is scarce. In the present study, four HXKs were firstly identified in the genome of and .

Associations of environmental factors with total cholesterol level of middle-aged and elderly people in China.

Background: Dyslipidemia is a key factor causing cardio cerebrovascular diseases, and the total cholesterol (TC) is an important lipid indicator among them. Studies have shown that environmental factors have a strong association with TC levels. Previous studies only focused on the seasonal variation of TC level and the short-term effects of some environmental factors on TC level over time, and few studies explored the geographical distribution of TC level and quantified the impact of environmental factors in space.

Genetic Polymorphisms of Nuclear Factor-κB Family Affect the Bone Mineral Density Response to Zoledronic Acid Therapy in Postmenopausal Chinese Women.

The aim of this study was to explore the allelic association between genetic polymorphisms of the NF-κB pathway and the variance of clinical effects of zoledronic in postmenopausal Chinese women with osteoporosis. In the study, 110 Chinese postmenopausal women with osteoporosis were recruited. Every patient received zoledronic once a year.

Steroids Therapy in Patients With Severe COVID-19: Association With Decreasing of Pneumonia Fibrotic Tissue Volume.

Background: We use longitudinal chest CT images to explore the effect of steroids therapy in COVID-19 pneumonia which caused pulmonary lesion progression.

Materials And Methods: We retrospectively enrolled 78 patients with severe to critical COVID-19 pneumonia, among which 25 patients (32.1%) who received steroid therapy.

Relationship between ambient air pollution and preterm birth: a retrospective birth cohort study in Yan'an, China.

Preterm birth (PTB) has been associated with exposure to air pollution, but it is unclear whether effects might vary among air pollution sources in a valley city, and yet few studies have investigated refined susceptible windows for PTB. We performed a retrospective birth cohort study in Yan'an city, a typical valley city in the west of China, and analyze the effects of air pollutants on premature delivery, identify critical windows for maternal air pollutants exposure and PTB. The pregnant women who gave birth in the Affiliated Hospital of Yan'an University and Yan'an people's Hospital from January 1, 2018 to December 31, 2019 were selected as the research objects.

Nonlinear associations between environmental factors and lipid levels in middle-aged and elderly population in China: A national cross-sectional study.

Background: Blood lipid is an important factor affecting cardiovascular disease in middle-aged and elderly people. At present, the associations between environmental factors and blood lipid level in elderly people has been controversial, and the nonlinear effect of their relationship is lack of research.

Methods: This study used data from a national cross-sectional survey of blood lipid levels in 13,354 subjects and data from environmental monitoring sites.