Myocardial infarction (MI) is followed by irreversible damage to the myocardium, which eventually evolves into ventricular remodeling and heart failure. An imbalanced inflammatory response after MI can exacerbate myocardial injury. Current strategies to modulate inflammation and thereby improve myocardial tissue repair are limited.
View Article and Find Full Text PDFJ Cancer Surviv
September 2025
Purpose: Guided by the COM-B model ("capability," "opportunity," "motivation," and "behavior"), this study explores the factors and potential mechanisms of social withdrawal in children with cancer.
Methods: The illness experiences shared by families of children with cancer on the internet provided a unique opportunity for this study. An interdisciplinary research team was formed, and a hybrid thematic analysis was conducted to examine 41 online illness narratives describing the experiences of children (≤ 18 years old) diagnosed with cancer.
Alzheimer's disease (AD) manifests as progressive cognitive deterioration with significant impact on patient independence and quality of life. While conventional treatments offer limited efficacy, Traditional Chinese Medicine (TCM) rehabilitation nursing presents a complementary approach deserving systematic evaluation. To synthesize existing evidence on the efficacy of TCM rehabilitation nursing for cognitive enhancement in AD through comprehensive meta-analysis.
View Article and Find Full Text PDFBackground: China's rapidly aging population and the limitations of traditional home-based care have prompted many older adults and their families to consider Continuing Care Retirement Communities (CCRCs) as a comprehensive option. However, the decision-making process for this transition remains underexplored. This study aims to systematically explore how older adults navigate the decision to move to CCRCs, to guide service improvements and inform policy.
View Article and Find Full Text PDFNat Commun
June 2025
Artificial stimulus-responsive membranes, particularly those responsive to different solvents, have important applications in complex and graded separation systems. Inspired by natural lipid membrane that alters mass transport behavior in response to interactions with various solvents, we report that incorporating porous graphene (PG) into graphene oxide (GO) membrane enables smart and switchable molecular sieving reversibly responsive to solvent types. The membrane shows high permeance for water and methanol, 45.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
June 2025
Background: The accumulated evidence suggested that postpartum depression was mainly associated with maternal-infant bonding. However, this link needed to be further explained by potential mediating factors. This study aimed to investigate the impact of postpartum depression on maternal-infant bonding, examining the mediating roles of mentalizing and parenting self-efficacy.
View Article and Find Full Text PDFBackground: Attention deficit hyperactivity disorder (ADHD) prevalence in Canadian children increased 3.5-fold between 1999 and 2012, influenced by genetics and perinatal environmental factors. During the same period, cesarean section rates rose from 18.
View Article and Find Full Text PDFBackground: Postpartum depression is a prevalent issue that significantly impacts the mental health of women, placing a substantial burden on individuals, families, and society. With the increasing evidence of postpartum depression prevention, conducting comprehensive assessments becomes essential to facilitate future clinical practices.
Methods: The systematic review and meta-analysis examined psychological and psychosocial interventions to prevent postpartum depression in perinatal women (antenatal and postnatal up to 12 months).
ACS Appl Mater Interfaces
November 2024
Valve replacement is the most effective means of treating heart valve diseases, and transcatheter heart valve replacement (THVR) is the hottest field at present. However, the durability of the commercial bioprosthetic valves has always been the limiting factor restricting the development of interventional valve technology. The chronic inflammatory reaction, calcification, and difficulty in endothelialization after the implantation of a glutaraldehyde cross-linked porcine aortic valve or bovine pericardium often led to valve degeneration.
View Article and Find Full Text PDFBMC Oral Health
October 2024
Background: Dentin hypersensitivity (DH) is a common oral condition that is associated with severe dental pain. Pain relief is a key focus of the treatment of DH. The purpose of this study was to evaluate the blocking and antacid effects of gallic acid (GA) combined with sodium fluoride (NaF) on dentinal tubules in vitro.
View Article and Find Full Text PDFFront Immunol
October 2024
Background: In recent years, there has been a significant decrease in the desire to have children among Chinese women of childbearing age, particularly for the first child. This trend has sparked a growing interest in understanding the underlying factors. Although perceived stress has been speculated as an important factor in decreasing fertility intention, the precise mechanism is unclear.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
October 2024
In the field of industrial semi-hydrogenation of trace alkynes amidst alkene feedstocks, the pivotal challenge lies in circumventing the hydrogenation of alkenes. Herein, we present Zr(OH) as an innovative catalyst for the semi-hydrogenation of phenylacetylene, demonstrating remarkable selectivity towards styrene (>96 %), while exhibiting inactivity towards free styrene. Notably, Zr(OH) achieves a 95 % conversion of quasi-industry 1 mol % phenylacetylene within styrene, with a mere 0.
View Article and Find Full Text PDFBackground: During the prolonged COVID-19 pandemic, hospitals became focal points for normalised prevention and control. In this study, we investigated the feasibility of an inpatient bed reservation system for cancer patients that was developed in the department?s public WeChat account. We also explored its role in improving operational efficiency and nursing quality management, as well as in optimising nursing workforce deployment.
View Article and Find Full Text PDFFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the data featured in Figs. 1, 4 and 5 (including western blotting data) were strikingly similar to data that had appeared in a different form in a different article by different authors at different research institutes. Owing to the fact that the contentious data in the above article had already been accepted for publication in another article prior to its submission to , the Editor has decided that this paper should be retracted from the Journal.
View Article and Find Full Text PDFWe explored the sex difference in lung ischemia-reperfusion injury (LIRI) and the role and mechanism of estrogen (E2) and angiotensin II (Ang II) in LIRI. We established a model of LIRI in mice. E2, Ang II, E2 inhibitor (fulvestrant), and angiotensin II receptor blocker (losartan) were grouped for treatment.
View Article and Find Full Text PDFIntroduction: Excessive generation of reactive oxygen species (ROS) following myocardial ischemia-reperfusion (I/R) can result in additional death of myocardial cells. The rapid clearance of ROS after reperfusion injury and intervention during subsequent cardiac repair stages are crucial for the ultimate recovery of cardiac function.
Methods: Magnesium-doped mesoporous bioactive glasses were prepared and loaded with the antioxidant drug gallic acid into MgNPs by sol-gel method.
Background: Abnormal blood potassium levels are associated with an increased risk of cardiometabolic diseases and mortality in the general population; however, evidence regarding the association between dyskalemia and mortality among patients with cardiovascular disease (CVD) remains inconclusive. This study aimed to evaluate the association of potassium levels with all-cause and cardiovascular mortality among patients with CVD.
Methods: PubMed, Embase, Web of Science, and Cochrane Library databases were searched up to August 2023 to identify relevant cohort studies among patients with CVD, such as myocardial infarction, stroke, and heart failure.
Background & Aims: Epidemiologic studies have examined the association between dietary fatty acids and type 2 diabetes risk in general populations. Evidence regarding their associations with gestational diabetes mellitus (GDM) risk remains limited. This study aimed to evaluate prepregnancy fatty acids intake in relation to GDM risk.
View Article and Find Full Text PDFThe Fe-based Fischer-Tropsch synthesis (FTS) catalyst shows a rich phase chemistry under pre-treatment and FTS conditions. The exact structural composition of the active site, whether iron or iron carbide (FeC), is still controversial. Aiming to obtain an insight into the active sites and their role in affecting FTS activity, the swarm intelligence algorithm is implemented to search for the most stable Fe(100), Fe(110), Fe(210) surfaces with different carbon ratios.
View Article and Find Full Text PDFCrit Rev Food Sci Nutr
November 2024
Epidemiological evidence on the association between potassium and cardiometabolic outcomes remains controversial. This study aimed to examine associations of dietary intake and blood and urinary levels of potassium with risk of type 2 diabetes, cardiovascular disease (CVD), and mortality. Relevant prospective studies were retrieved through a comprehensive search of four electronic databases up to July 1, 2023.
View Article and Find Full Text PDFSci Rep
September 2023
Aberrant levels of the G2/M cyclin cyclin B1 (gene CCNB1) have been associated with multiple cancers; however, the literature lacks a focused and comprehensive analysis of the regulation of this important regulator of cell proliferation in cancer. Through this work, we performed a pancancer analysis of the levels of CCNB1 and dissected aspects of regulation and how this correlates with cancer prognosis. We comprehensively evaluated the expression and promoter methylation of CCNB1 across 38 cancers based on RNA sequencing data obtained from the Cancer Genome Atlas (TCGA).
View Article and Find Full Text PDFLoop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique that has been widely used for the detection of pathogens in many organisms. Current LAMP-based sensors usually require the LAMP products to be labeled in order for them to be detected. Here, we present a novel label-free LAMP chip, which consists of a nanopore thin-film sensor embedded inside a LAMP reaction chamber.
View Article and Find Full Text PDFThis research focuses on the relationship between the changes in peripheral blood eosinophils (PBEs) perioperatively and the prognosis of lung cancer. The study included 414 lung cancer patients. These patients were divided into the DOWN (186 patients) and UP (209 patients) groups according to perioperative changes in PBEs.
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