Enhancing porcine myofibrillar protein properties via twin-screw extrusion-modified Stropharia rugosoannulata mushroom: Gelation, structure, and in vitro digestibility.

This study explored how extrusion-modified Stropharia rugosoannulata powder (ESrP) (0-10 %) influences porcine myofibrillar protein (MP) gel properties. Optimal ESrP incorporation (4-8 %) significantly reduced cooking loss by 15-22 % (P < 0.05) and increased gel strength by up to 80.

Impact of subclinical hypothyroidism on endocrine features in patients with polycystic ovary syndrome.

Background: Polycystic ovary syndrome (PCOS) and subclinical hypothyroidism (SCH) are both common endocrine disorders. This study investigates the impact of SCH on the endocrine features of patients diagnosed with PCOS.

Methods: This retrospective study included 124 women diagnosed with PCOS between January 2020 and November 2022.

Recent Advances in Thermochemical Water Splitting for Hydrogen Production Using Mixed Ionic-Electronic Conducting Membrane Reactors.

Under the accelerating global energy restructuring and the deepening carbon neutrality strategy, hydrogen energy has emerged with increasing strategic value as a zero-carbon secondary energy carrier. Water electrolysis technology based on renewable energy is regarded as an ideal pathway for large-scale green hydrogen production. However, polymer electrolyte membrane (PEM) conventional water electrolysis faces dual constraints in economic feasibility and scalability due to its high electrical energy consumption and reliance on noble metal catalysts.

Shengmai Jianghuang San Enhances Radiosensitivity of Hypoxic Nasopharyngeal Carcinoma by Inhibiting Cancer Stemness.

Background: Radiotherapy is the preferred treatment for nasopharyngeal carcinoma (NPC). Previous studies by our research team have shown that Shengmai Jianghuang San (SMJHS) inhibits the proliferation and migration of hypoxic NPC cells, thereby enhancing their radiosensitivity.

Aim: This study aimed to explore the effects and potential molecular mechanisms of action of SMJHS on NPC cell stemness.

A Tailored Quinoline-Locked Covalent Organic Framework for Metal-Free Photocatalytic α-Amino C-H Annulation.

Metal-free α-amino C-H annulation via photocatalysis stands as a pioneering strategy for accessing heterocyclic compounds. Imine-linked covalent organic frameworks (ILCOFs), known for their photonic excitation potential, have been underutilized in C-H annulation due to inherent photochemical instability and inefficient C-H activation. Here, we propose a novel locking strategy using chlorotrimethylsilane-catalyzed cyclization to convert ILCOF- into stable QLCOF- with methylquinoline motifs, thereby establishing it as a robust photocatalytic platform for metal-free α-amino C-H annulation.

The Formation and Change of Volatile Flavor Compounds During the Cooking of Sheep Bone Soup.

To investigate the formation of flavor compounds in sheep bone soup, E-nose, gas chromatograph (GC), and gas chromatography-mass spectrometry (GC-MS) were used to determine the changes in lipid oxidation, Maillard reaction, and volatile flavor compounds during the slow cooking process of 4 h. The thiobarbituric acid reactive substances (TBARS) value began to increase significantly ( < 0.05) after 2 h of cooking, reaching its peak in the third hour before significantly decreasing.

Exploring the bidirectional causal relationship between Autism Spectrum Disorder and Schizophrenia using Mendelian randomization.

Autism Spectrum Disorder (ASD), characterized mainly by stereotyped behaviors and social impairments, affects about one in 100 children worldwide. Schizophrenia (SCZ), a chronic mental illness, affects 1% of the global population. The pathogenesis and specific treatment strategies for ASD and SCZ remain unclear.

Correction: Acoustic modulation and non-contact atomization of droplets based on the Fabry-Pérot resonator.

Correction for 'Acoustic modulation and non-contact atomization of droplets based on the Fabry-Pérot resonator' by Jingjun Li , , 2024, , 2418-2427, https://doi.org/10.1039/D4LC00071D.

Citric acid vapor-assisted crosslinking of zein/PEG composite nanofiber membrane embedded with nisin by electrospinning for the cooled goose meat preservation.

This study demonstrated the fabrication of zein/polyethylene glycol/nisin (zein/PEG/nisin) nanofiber membrane and cross-linked by citric acid vapor (zein/PEG/nisin/C). The distribution within the whole nanofiber membranes was monitored by scanning electron microscopy (SEM). Studies using thermogravimetric analysis (TGA) and Fourier transform infrared spectroscopy (FTIR) validated the effectiveness nisin encapsulation and molecular interactions.

Causal Relationship between Attention-Deficit Hyperactivity Disorder and Autism Spectrum Disorder: A Two-Sample Mendelian Randomization.

Despite the exponential increase in the incidence rate of Autism spectrum disorder (ASD), effective therapies for the disorder are still limited. According to vast clinical observations, the pathogeneses of ASD and Attention-deficit hyperactivity disorder (ADHD) share a great deal of similarities. This serves as a prompt to investigate, in this study, whether patients with ADHD are at a higher risk for ASD, which is significant for disease prevention.

In Situ Integration of Metallic Catalytic Sites and Photosensitive Centers within Covalent Organic Frameworks for the Enhanced Photocatalytic Reduction of CO.

Covalent organic frameworks (COFs) are a promising platform for heterogeneous photocatalysis due to their stability and design diversity, but their potential is often restricted by unmanageable targeted excitation and charge transfer. Herein, a bimetallic COF integrating photosensitizers and catalytic sites is designed to facilitate locally ultrafast charge transfer, aiming to improve the photocatalytic reduction of CO. The strategy uses a "one-pot" method to synthesize the bimetallic COF (termed PBCOF) through in situ Schiff-base condensation of Pyrene with MBpy (M = Ru, Re) units.

An Evaluation of the Effects of Pepper () Leaf Extract on the Physiochemical Properties and Water Distribution of Chinese Cured Meat (Larou) During Storage.

In this study, pepper () leaf (ZL) extract was added to larou to investigate the improvement in the quality of physicochemical properties, texture, water distribution, and microorganism growth during storage for 20 days. Based on the results, the addition of ZL extract significantly retarded the increase in cooking loss, TBARS value, hardness, and microorganism growth. Moreover, the addition of ZL extract decreased the pH value, lightness, and microorganism counts, and increased the moisture content, total soluble protein content, * value, * value, and chewiness.

Evaluation of the water state and protein characteristics of Tibetan pork under the storage conditions of modified atmosphere packaging: Effect of oxygen concentration.

To explore the changes in water status and protein characteristics of Tibetan pork (TP) under modified atmosphere packaging (MAP) with different oxygen concentrations compared to Duroc×Landrace×Yorkshire pork (DLY), the water holding capacity (WHC), water distribution, protein oxidation, and conformation of both types were determined. Results indicate that under MAP, TP pork and DLY pork exhibited higher water retention and lower protein oxidation compared to air packaging. However, with increased oxygen concentration in the MAP, protein oxidation intensified, leading to reduced WHC in the pork.

Heavy-Atom-Free Covalent Organic Frameworks for Organic Room-Temperature Phosphorescence via Förster and Dexter Energy Transfer Mechanism.

Covalent organic frameworks (COFs), with their accessible nanoscale porosity, selectable building blocks, and precisely engineered topology, offer unique benefits in the design of room-temperature phosphorescent (RTP) materials. However, their potential has been limited by phosphorescence quenching caused by interlayer π-π stacking interactions. This paper presents a novel strategy to enhance RTP in heavy-atom-free COFs by employing a donor-acceptor (D-A) system that leverages the Förster resonance energy transfer (FRET) and Dexter energy transfer (DET) mechanisms.

Optically Mediated Nonvolatile Resistive Memory Device Based on Metal-Organic Frameworks.

Metal-organic frameworks (MOFs), characterized by tunable porosity, high surface area, and diverse chemical compositions, offer unique prospects for applications in optoelectronic devices. However, the prevailing research on thin-film devices utilizing MOFs has predominantly focused on aspects such as information storage and photosensitivity, often neglecting the integration of the advantages inherent in both photonics and electronics to enhance optical memory. This work demonstrates a light-mediated resistive memory device based on a highly oriented porphyrin-based MOFs film, in which the resistance state of the memristor is modulated by light, realizing the integration of the perception and storage of optical information.

Inkjet Printing Photoresist with Ultralow Viscosity on Silicon Wafers for Uniform Coating.

Inkjet printing is introduced into the photoresist coating process for uniform photoresist film formation on silicon wafers with the in-house inkjet experimental prototype. The optimization of a dual negative voltage waveform is proposed to achieve stable droplet jetting for the ultralow viscosity (0.71 mPa·s) photoresist with a 1:10 dilution ratio employed in the semiconductor packaging processes.

No causal association between the volume of strenuous exercise and coronary atherosclerosis: a two-sample Mendelian randomization study.

Objective: Several observational studies have shown that high-volume and high-intensity exercise training increases the prevalence and severity of coronary atherosclerosis, but the causal effect still remains uncertain. This study aims to explore the causal relationship between the volume of strenuous exercise (SE) and coronary atherosclerosis (CA) using the Mendelian randomization (MR) method.

Method: The exposure factors were two basic parameters of the volume of strenuous exercise (duration and frequency of strenuous exercise), the outcome factor was coronary atherosclerosis, and the relevant genetic loci were extracted from the summary data of the genome-wide association study (GWAS) as the instrumental variables, and MR analyses were performed using the inverse variance weighting (IVW) method, the weighted median method, and the MR-egger method.

Optimizing preparation of low-NaCl protein gels from goose meat and understanding synergistic effects of pH/NaCl in improving gel characteristics.

This study explored the feasibility of partially substituting NaCl with MgCl in preparing gel products from goose meat. Furthermore, the effects of synergistic interaction between different pH levels and NaCl concentrations on the structure and characteristics of the gels were explored by analyzing their secondary structure, microstructure, and water-distribution properties. The results showed that NaCl could be partially substituted by MgCl, with the optimal preparation conditions: NaCl (0.

Acoustic modulation and non-contact atomization of droplets based on the Fabry-Pérot resonator.

A non-contact ultrasonic atomization based on the Fabry-Pérot resonator is proposed to obtain atomized droplets with a reduced droplet diameter and concentrated droplet distributions. To better understand the mechanism inside the acoustic chamber, the acoustic-fluid interactions are numerically explored inside the Fabry-Pérot resonator to achieve the precise modulation of droplets. The influence of the acoustic chamber's geometry and the ultrasonic properties on the atomized droplet diameter and distributions is investigated, aiming to establish matching relationships between the atomized droplet diameter and the geometry of the acoustic chamber.

Femtosecond Electron Diffraction Reveals Local Disorder and Local Anharmonicity in Thermoelectric SnSe.

In addition to long-range periodicity, local disorder, with local structures deviating from the average lattice structure, dominates the physical properties of phonons, electrons, and spin subsystems in crystalline functional materials. Experimentally characterizing the 3D atomic configuration of such a local disorder and correlating it with advanced functions remains challenging. Using a combination of femtosecond electron diffraction, structure factor calculations, and time-dependent density functional theory molecular dynamics simulations, the static local disorder and its local anharmonicity in thermoelectric SnSe are identified exclusively.

The application of encapsulation technology in the food Industry: Classifications, recent Advances, and perspectives.

Encapsulation technology has been extensively used to enhance the stability, specificity, and bioavailability of essential food ingredients. Additionally, it plays a vital role in improving product quality and reducing production costs. This study presents a comprehensive classification of encapsulation techniques based on the state of different cores (solid, liquid, and gaseous) and offers a detailed description and analysis of these encapsulation methods.

The interaction between DNA methylation and tumor immune microenvironment: from the laboratory to clinical applications.

DNA methylation is a pivotal epigenetic modification that affects gene expression. Tumor immune microenvironment (TIME) comprises diverse immune cells and stromal components, creating a complex landscape that can either promote or inhibit tumor progression. In the TIME, DNA methylation has been shown to play a critical role in influencing immune cell function and tumor immune evasion.