Impact of physical exercise habit on career decision-making behavior in college students: a chain mediating effect of self-efficacy and psychological resilience.

Objective: To explore the mechanism through which physical exercise habits influence college students' career decision-making behavior, and to verify the independent and chain mediation effects of self-efficacy and psychological resilience within this relationship.

Methods: Using stratified random sampling, questionnaires were distributed to universities students across China, and valid questionnaires were collected. The Physical Activity Rating Scale (PARS-3), General Self-Efficacy Scale (GSES), Connor-Davidson Resilience Scale (CD-RISC-10), and Career Decision-Making Difficulty Scale (CDMP) were employed.

Flushing peripheral intravenous catheters: A scoping review.

Background: Peripheral intravascular catheters (PIVCs) are indispensable vascular access devices in healthcare, facilitating the administration of intravenous therapies. Despite their vital role, PIVCs are frequently associated with complications such as occlusion, infection, and thrombosis, which contribute to catheter failure. Flushing catheters is one of the most common practices during PIVC maintenance, as it cleans the internal catheter lumen, ensuring patency and reducing the risk of complications.

Strength and permeability performance of excavated waste mud stabilized with ternary industrial byproducts.

To address the dual challenges of improving strength and reducing permeability in solidified soils produced from excavated waste mud, this study develops a sustainable stabilization method using industrial by-products. A ternary solid waste-based cementitious material (SWC), consisting of ground granulated blast furnace slag (GGBS), steel slag (SS), and desulfurization gypsum (DG), was optimized through an extreme vertex mixture design. The results demonstrate that, under appropriate mix proportions, the solidified soil using SWC can achieve comparable unconfined compressive strength (UCS) at 7 d and superior strength at 28 d compared to ordinary Portland cement (OPC).

A Reliability Generalization Meta-Analysis of the Antisocial Process Screening Device.

Although the Antisocial Process Screening Device (APSD) is one of the most widely used instruments for assessing psychopathic traits, the reliability estimates of the APSD show great heterogeneity across different studies. This investigation evaluated the reliability of the APSD using a reliability generalization meta-analytic technique across 158 studies ( = 75,749). The APSD demonstrated marginal to acceptable coefficient alphas ranging from 0.

Ferritin-based nanoparticle vaccine protects neonatal piglets against porcine epidemic diarrhea virus challenge following immunization of pregnant sows.

Porcine epidemic diarrhea virus (PEDV) is an enteropathogenic coronavirus that causes severe diarrhea and high mortality in neonatal piglets, resulting in significant economic losses to the pig industry worldwide. Given that current commercial vaccines lack adequate protection against variant PEDV strains, there is an urgent need for the development of more effective vaccines to control PEDV infection. Here, a novel nanoparticle vaccine displaying the core neutralizing epitope CO-26 K-equivalent (COE) of PEDV spike protein was developed using Helicobacter pylori ferritin as an antigen delivery system, and its protective efficacy against the highly virulent PEDV LYL strain in suckling piglets was evaluated following immunization of pregnant sows.

The effects of aerobic exercise in patients with cancer-related fatigue: A systematic review and meta-analysis.

Background: Cancer-related fatigue (CRF) is characterized by an unusual and persistent sensation of tiredness that can occur during or after treatment, potentially impacting both physical and mental capability, and which does not ameliorate with rest. Aerobic exercise (AE) has been identified as a potent modality to mitigate the severity of CRF in such patients.

Objective: This study aims to investigate the efficacy of AE in alleviating CRF among patients.

Ocular Manifestations of Mpox and Other Poxvirus Infections: Clinical Insights and Emerging Therapeutic and Preventive Strategies.

Poxvirus infections, particularly those caused by the monkeypox virus, have emerged as significant public health threats. Ocular manifestations constitute a severe potential clinical complication associated with these infections, potentially resulting in permanent visual impairment in afflicted patients. This review aimed to examine the clinical spectrum of ocular manifestations associated with mpox and other poxvirus infections and to evaluate current management strategies alongside emerging therapeutic interventions and prevention strategies.

Fusobacterium mortiferum and its metabolite 5-aminovaleric acid promote the development of colorectal cancer in obese individuals through Wnt/β-catenin pathway by DKK2.

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, with high incidence and mortality rates. An increasing body of research suggests that obesity is a significant risk factor for the development of CRC. Moreover, recent findings have highlighted the close association between the gut microbiota and both obesity and CRC.

Assembly mechanism of the β-carboxysome shell mediated by the chaperone CcmS.

Carboxysomes are self-assembled bacterial microcompartments (BMCs) that encapsulate the enzymes RuBisCO and carbonic anhydrase into a proteinaceous shell, enhancing the efficiency of photosynthetic carbon fixation. The chaperone CcmS was reported to participate in the assembly of β-carboxysomes; however, the underlying molecular mechanism remains elusive. We report the crystal structure of CcmS from Synechocystis sp.

Mapping existing research on flushing peripheral vascular catheters: a scoping review protocol.

Introduction: The peripheral vascular catheter (PVC) is the most common intravenous medical device used in hospitals, given it is crucial for the delivery of intravenous therapies. Despite its widespread use, PVC complications such as occlusion, infiltration, extravasation, phlebitis, thrombophlebitis, catheter-related thrombosis and catheter-related bloodstream infection significantly affect patient safety, leading to increased morbidity and healthcare costs. One approach to maintain PVC patency and therefore device longevity is to flush the PVC.

Rubber band ligation or shaobei injection for the endoscopic treatment of symptomatic hemorrhoids? A retrospective study.

Background: It is unknown whether Shaobei injection is superior to band ligation for endoscopic symptomatic hemorrhoid treatment. We compared the clinical efficacy, safety, and health economics of the two techniques.

Aims: This study aims to compare the efficacy, safety and health economics of endoscopic injection of Shaobei and endoscopic ligation in the treatment of grade I-IV symptomatic hemorrhoids.

Different types of pesticide exposure and lung cancer incidence in the Agricultural Health Study cohort: A systematic review and meta-analysis.

Lung cancer is the dominant cause of worldwide cancer mortality. The relationship between pesticide exposure and lung cancer risk has shown mixed results epidemiologically. We hypothesized this discrepancy could arise from the varying effects of different pesticides and conducted this meta-analysis by using three pesticide classification schemes to examine the implications of diverse pesticide exposure types on lung cancer risk.

Analysis of treatment methods and relapse factors of postoperative anastomotic stenosis in colorectal cancer.

Background: Anastomotic stenosis following surgical intervention for colorectal cancer is a frequently encountered complication. Nevertheless, the optimal approach to effectively manage anastomotic stenosis at varying distances from the anal margin remains uncertain. The primary objective of this research endeavor was to explore the risk factors associated with recurrent anastomotic stenosis subsequent to colorectal cancer surgery, as well as to evaluate potential strategies for its management.

The influence of physical exercise on negative emotions in adolescents: a meta-analysis.

Background: Adolescence is also accompanied by ongoing mood changes (relative to childhood and adulthood), which can trigger more extreme negative emotional responses. Physical exercise alleviates negative emotions and reduces the risk of mental illness. However, the effect of physical exercise on negative emotions in adolescents is unclear, so it is valuable to synthesize previous studies with meta-analysis.

The association between physical activity and anxiety in college students: parallel mediation of life satisfaction and self-efficacy.

Objective: To explore the functions that physical activity (PA), life satisfaction, and self-efficacy have in the process of coping with anxiety among Chinese college students, and to explore the mediating role of life satisfaction and self-efficacy in this process.

Methods: Participants were 358 college students (186 males, 172 females, mean age 20.88, SD = ±1.

Correlation between Vegetable and Fruit Intake and Cognitive Function in Older Adults: A Cross-Sectional Study in Chongqing, China.

Objective: To explore the correlation between different types of vegetable and fruit intake and cognitive function among the older adults in Chongqing, China, and to provide a scientific basis for developing efficient lifestyle interventions for the prevention of Mild Cognitive Impairment (MCI).

Method: Approximately 728 older adults in urban and rural areas of Chongqing were surveyed using face-to-face questionnaires. Cognitive function was assessed with the Montreal Cognitive Assessment-Basic (MoCA-B) scale, and the vegetable and fruit intake groups were investigated with the Simple Food Frequency Counting Survey Scale.

The impact of the physical activity intervention on sleep in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis.

Objective: The purpose of this review was to synthesize the current literature on the relationship between sleep and physical activity in children and adolescents with neurodevelopmental disorders.

Methods: Articles were searched in PubMed, Web of Science, EBSCO, Cochrane, and Embase until April 2024. The meta-analysis was performed using Review Manager 5.

Direct visualization endoscopic retrograde appendicitis therapy for treatment of acute uncomplicated appendicitis.

Objective: To investigate the diagnostic and therapeutic value of direct visualization (single-use eyeMax subscope) endoscopic management of acute uncomplicated appendicitis.

Methods: Thirty-six patients diagnosed with acute uncomplicated appendicitis, confirmed by computed tomography or ultrasonography, from Jan 2023 to Feb 2024 were enrolled in this study. We collected demographics, colonoscopy findings, subscope findings, clinical outcomes of endoscopic retrograde appendicitis therapy (ERAT), and adverse events associated with ERAT.

Influence of aerobic exercise on depression in young people: a meta-analysis.

Objective: To investigate the influence of aerobic exercise on depression among the young people.

Data Sources: PubMed, Web of science, Embase, Cochrane, EBSCO were searched from inception to November 2023.

Study Selection: RCT studies, assessing the use of aerobic exercise in young people aged 6-35 years and then determining the development of depression in young people (aged 6-35 years), were selected, and mean ± SD values adjusted for the presence of baseline depression were extracted.

GSOOA-1DDRSN: Network traffic anomaly detection based on deep residual shrinkage networks.

One of the critical technologies to ensure cyberspace security is network traffic anomaly detection, which detects malicious attacks by analyzing and identifying network traffic behavior. The rapid development of the network has led to explosive growth in network traffic, which seriously impacts the user's information security. Researchers have delved into intrusion detection as an active defense technology to address this challenge.

Structure and assembly of the α-carboxysome in the marine cyanobacterium Prochlorococcus.

Carboxysomes are bacterial microcompartments that encapsulate the enzymes RuBisCO and carbonic anhydrase in a proteinaceous shell to enhance the efficiency of photosynthetic carbon fixation. The self-assembly principles of the intact carboxysome remain elusive. Here we purified α-carboxysomes from Prochlorococcus and examined their intact structures using single-particle cryo-electron microscopy to solve the basic principles of their shell construction and internal RuBisCO organization.

The FTO-CMPK2 Pathway in Fibroblast-like Synoviocytes Modulates Rheumatoid Arthritis Synovial Inflammation and Cartilage Homeostasis via mtDNA Regulation.

In rheumatoid arthritis (RA), a debilitating autoimmune disorder marked by chronic synovial inflammation and progressive cartilage degradation, fibroblast-like synoviocytes (FLS) are key pathogenic players. Current treatments targeting these cells are limited. Our study focused on the Fat Mass and Obesity-associated protein (FTO), known for its roles in cell proliferation and inflammatory response modulation, and its involvement in RA.