Automatic epileptic seizure detection method based on spatio-temporal feature fusion.

This paper proposes a spatiotemporal feature fusion method for automatic epileptic seizure detection, integrating Common Spatial Pattern (CSP) and Least Squares Support Vector Machine (LSSVM). First, it reconstructs electroencephalogram (EEG) noise using Ensemble Empirical Mode Decomposition (EEMD), then decomposes the original EEG signals using improved EEMD (IEEMD). Next, features are extracted from temporal and spatial dimensions to form a feature set.

Post-selection inference for the Cox model with interval-censored data.

We develop a post-selection inference method for the Cox proportional hazards model with interval-censored data, which provides asymptotically valid p-values and confidence intervals conditional on the model selected by lasso. The method is based on a pivotal quantity that is shown to converge to a uniform distribution under local parameters. Our method involves estimation of the efficient information matrix, for which several approaches are proposed with proof of their consistency.

The cytokine CSBF inhibits the IL-17A and TNF-α inflammatory pathways via SUSD2-ACT1 in keratinocytes and alleviates IMQ-induced psoriasis.

Overactivation of inflammatory signaling in keratinocytes is critical for psoriatic skin inflammation, but its regulatory mechanisms remain incompletely understood. Here, we demonstrate that the cytokine CSBF inhibits both individual and synergistic proinflammatory signaling induced by IL-17A and TNF-α (IL-17A/TNF-α) in keratinocytes, playing a protective role in psoriatic inflammation. The expression of CSBF was increased in the skin lesions and serum of psoriatic patients, and IL-17A/TNF-α enhanced its production.

Self-Assembled Monolayer Interface with Reconstructed Hydrogen-Bond Network for Enhanced CO Electroreduction.

CO electrolysis is a promising approach to reduce CO emissions while achieving high-value multi-carbon (C) products. Except for the key role of electrocatalyst for electrochemical CO reduction reaction (CORR), Reaction microenvironment is another critical factor influencing catalytic performance for these catalysts. Herein, a self-assembled monolayer (SAM) is proposed with reconstructed hydrogen-bond network to form an efficient three-phase interface that admins mass transport and ion-electron transfer.

Efficient Electrochemical-Enzymatic Conversion of PET to Formate Coupled with Nitrate Reduction Over Ru-Doped CoO Catalysts.

Electrochemical reforming presents a sustainable route for the conversion of nitrate (NO ) and polyethylene terephthalate (PET) into value-added chemicals, such as ammonia (NH) and formic acid (HCOOH). However, its widespread application has been constrained by low selectivity due to the complexity of reduction processes and thus energy scaling limitations. In this study, the atomically dispersed Ru sites in CoO synergistically interact with Co centers, facilitating the adsorption and activation of hydroxyl radicals (OH) and ethylene glycol (EG), resulting in a remarkable HCOOH selectivity of 99% and a yield rate of 11.

Durability analysis of rotary direct drive electro-hydraulic pressure servo valve based on failure physics principle.

The rotary direct drive electro-hydraulic servo valve (RDDPV) is extensively employed in hydraulic systems across aerospace, automotive, and various industrial sectors owing to its remarkable precision and rapid response characteristics. The investigation of the durability life of such devices, constituting intricate amalgamations of mechanical, electrical, and hydraulic components, has perennially posed a formidable challenge. To address this challenge, our study proposes a methodology grounded in failure mechanisms to systematically quantify the durability life of RDDPV.

Comprehensive modeling of a deflector jet pressure servo valve and analysis of key influences on the front stage.

The deflector jet pressure servo valve (DJPSV), a critical component of the aircraft brake servo system, requires a precise foundational model for performance analysis, optimization, and enhancement. However, the complexity of the jet process within the V-groove of the deflector plate presents challenges for accurate mathematical modeling. To address this issue, the paper takes the DJPSV as the research object, carries out detailed mathematical modeling of its components, analyzes the influencing factors of the performance of the key component-the front stage-and optimizes the design of the key factors.

Observed Effects on Very Early Pregnancy Linked to Ambient PM Exposure in China among Women Undergoing Fertilization-Embryo Transfer.

The adverse effect of ambient PM exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort of 141,040 cycles to evaluate the effect of PM exposure on the VEP using the fertilization and embryo transfer platform and high-resolution PM data in China. We first investigated the association between PM exposure 1 week before and 1 week after the embryo transfer date and VEP.

Specific Adsorption of Alkaline Cations Enhances CO-CO Coupling in CO Electroreduction.

Electrolyte alkaline cations can significantly modulate the reaction selectivity of electrochemical CO reduction (eCOR), enhancing the yield of the valuable multicarbon (C) chemical feedstocks. However, the mechanism underlying this cation effect on the C-C coupling remains unclear. Herein, by performing constant-potential AIMD simulations, we studied the dynamic behavior of interfacial K ions over Cu surfaces during C-C coupling and the origin of the cation effect.

Fabrication of Scalable Covalent Organic Framework Membrane-based Electrolytes for Solid-State Lithium Metal Batteries.

The conventional covalent organic framework (COF)-based electrolytes with tailored ionic conducting behaviors are typically fabricated in the powder morphology, requiring further compaction procedures to operate as solid electrolyte tablets, which hinders the large-scale manufacturing of COF materials. In this study, we present a feasible electrospinning strategy to prepare scalable, self-supporting COF membranes (COMs) that feature a rigid COF skeleton bonded with flexible, lithiophilic polyethylene glycol (PEG) chains, forming an ion conduction network for Li transport. The resulting PEG-COM electrolytes exhibit enhanced dendrite inhibition and high ionic conductivity of 0.

Theoretical Insights of Curvature Effects of FeN-Doped Carbon Nanotubes on ORR Activity.

The advancement of metal-air batteries is critically contingent on the progression of efficient catalysts for the oxygen reduction reaction (ORR). The potential applications of a series of FeN-doped carbon nanotubes (Fe-NCNTs) of varying diameters as ORR catalysts were examined using density functional theory. We explored the stability and electronic properties of Fe-NCNTs by analyzing the energy and examining the density of states.

Flexible iontronics with super stretchability, toughness and enhanced conductivity based on collaborative design of high-entropy topology and multivalent ion-dipole interactions.

All-solid-state ionic conductive elastomers (ASSICEs) are emerging as a promising alternative to hydrogels and ionogels in flexible electronics. Nevertheless, the synthesis of ASSICEs with concomitant mechanical robustness, superior ionic conductivity, and cost-effective recyclability poses a formidable challenge, primarily attributed to the inherent contradiction between mechanical strength and ionic conductivity. Herein, we present a collaborative design of high-entropy topological network and multivalent ion-dipole interaction for ASSICEs, and successfully mitigate the contradiction between mechanical robustness and ionic conductivity.

CO Intermediate-Assisted Dynamic Cu Sintering During Electrocatalytic CO Reduction on Cu-N-C Catalysts.

The electrochemical CO reduction reaction (eCORR) to multicarbon products has been widely recognized for Cu-based catalysts. However, the structural changes in Cu-based catalysts during the eCORR pose challenges to achieving an in-depth understanding of the structure-activity relationship, thereby limiting catalyst development. Herein, we employ constant-potential density functional theory calculations to investigate the sintering process of Cu single atoms of Cu-N-C single-atom catalysts into clusters under eCORR conditions.

A comparative analysis of the clinical pregnancy and perinatal outcomes between oocyte vitrification and embryo vitrification based on the propensity score matching method.

Purpose: This study investigated the safety and effectiveness of oocyte vitrification by comparing the clinical pregnancy and perinatal outcomes between transfer cycles of vitrified oocytes and those of vitrified embryos.

Methods: A retrospective cohort study was conducted to analyze the clinical data of patients who underwent cleavage-stage embryo transfer at the Department of Reproductive Medicine between January 2011 and June 2021. Seventy-seven transfer cycles of fresh cleavage-stage embryos developed from vitrified-thawed oocytes (oocyte vitrification group) and 2170 transfer cycles of vitrified-thawed cleavage-stage embryos developed from fresh oocytes (embryo vitrification group) were included.

Exploring the factors influencing the intention to clothing and textiles recycling among Chinese college students': a study based on TPB and VBN.

Recycling apparel and fabrics is essential for preserving resources and protecting the environment, providing considerable global advantages for ecology and society. This study sought to explore the participation of Chinese college students in the recycling of clothing and fabrics by combining the Theory of Planned Behavior (TPB), the Value-Belief-Norm theory (VBN), self-identity, school education, and perceived policy effectiveness to create a comprehensive model. A total of 1,027 valid samples were obtained through stratified sampling and random sampling, primarily sourced from Eastern China, and analyzed through Structural Equation Modeling (SEM) utilizing AMOS.

Effects of chromosomal translocation characteristics on fertilization and blastocyst development - a retrospective cohort study.

Objective: To determine the effect of different translocation characteristics on fertilization rate and blastocyst development in chromosomal translocation patients.

Methods: This retrospective cohort study was conducted at the Third Affiliated Hospital of Zhengzhou University From January 2017 to December 2022.All couples were diagnosed as reciprocal translocation or Robertsonian translocation by karyotype of peripheral blood lymphocytes test.

Analysis of the static and dynamic characteristics of the electro-hydraulic pressure servo valve of robot.

In this study, we comprehensively investigate the structure and operational principles of the Rotary Direct Drive Electro-Hydraulic Pressure Servo Valve (RDDPV). Our objective is to establish the dynamics equations governing the motor, slide valve, and bias mechanism of the valve. Additionally, we construct a mathematical model for the servo valve controller, while ensuring the linearization of the controller model.

Emerging Electrocatalysts in Urea Production.

Urea synthesis from abundant CO and N-feedstocks via renewable electricity has attracted increasing interests, offering a promising alternative to the industrial-applied Haber-Meiser process. However, the studies toward electrochemical urea production remain scarce and appeal for more research. Herein, in this perspective, an up-to-date overview on the urea electrosynthesis is highlighted and summarized.

Theoretical Study on B-doped FeN Catalyst for Potential-Dependent Oxygen Reduction Reaction.

Electrochemical reactions mostly take place at a constant potential, but traditional DFT calculations operate at a neutral charge state. In order to really model experimental conditions, we developed a fixed-potential simulation framework via the iterated optimization and self-consistence of the required Fermi level. The B-doped graphene-based FeN sites for oxygen reduction reaction were chosen as the model to evaluate the accuracy of the fixed-potential simulation.

Echinatin maintains glutathione homeostasis in vascular smooth muscle cells to protect against matrix remodeling and arterial stiffening.

Decreased vascular compliance of the large arteries as indicated by increased pulse wave velocity is shown to be associated with atherosclerosis and the related cardiovascular events. The positive correlation between arterial stiffening and disease progression derives a hypothesis that softening the arterial wall may protect against atherosclerosis, despite that the mechanisms controlling the cellular pathological changes in disease progression remain unknown. Here, we established a mechanical-property-based screening to look for compounds alleviating the arterial wall stiffness through their actions on the interaction between vascular smooth muscle cells (VSMCs) and the wall extracellular matrix (ECM).

Convertible Thermal Meta-Structures via Hybrid Manufacturing of Stereolithography Apparatus 3D Printing and Surface Metallization for Thermal Flow Manipulation.

For manipulating heat flow according to human desire, thermal metamaterial structures (meta-structures) have attracted growing interest. Based on the transformation thermotics and the effective medium approximation theory, we designed and fabricated a convertible thermal meta-structural device to demonstrate that multiple different heat-flow manipulations could be conducted using a single thermal meta-structural device. The convertible meta-structures were designed by discretizing a two-dimensional plane and separating multiple square unit modules with stripe-shaped dissimilar materials of the Polydimethylsiloxane (PDMS) and solid resin with surface metallized copper (Cu).

[The detection and evaluation of vascular stiffness].

Cardiovascular homeostasis is regulated by both physical and chemical factors. Vascular stiffness, a physical property of vessel, is crucial in maintaining the physiological function of vasculature. Vascular stiffness has been indicated to be correlated with hypertension, heart failure and other cardiovascular diseases.

Selective Laser Melting (SLM) Additively Manufactured CoCrFeNiMn High-Entropy Alloy: Process Optimization, Microscale Mechanical Mechanism, and High-Cycle Fatigue Behavior.

The equiatomic CoCrFeNiMn high-entropy alloy (HEA) possesses excellent properties including exceptional strength-ductility synergy, high corrosion resistance, and good thermal stability. Selective laser melting (SLM) additive manufacturing facilitates the convenient fabrication of the CoCrFeNiMn HEA parts with complex geometries. Here, the SLM process optimization was conducted to achieve a high relative density of as-built CoCrFeNiMn HEA bulks.

Liquid-Liquid Phase Separation of DDR1 Counteracts the Hippo Pathway to Orchestrate Arterial Stiffening.

Background: The Hippo-YAP (yes-associated protein) signaling pathway is modulated in response to various environmental cues. Activation of YAP in vascular smooth muscle cells conveys the extracellular matrix stiffness-induced changes in vascular smooth muscle cells phenotype and behavior. Recent studies have established a mechanoreceptive role of receptor tyrosine kinase DDR1 (discoidin domain receptor 1) in vascular smooth muscle cells.