Publications by authors named "Jiani Chen"

Food sharing is very common in the animal kingdom. Despite extensive research, the mechanisms underlying food sharing remain debated. Moreover, the majority of studies on food sharing in non-human animals have been conducted under controlled environments.

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RSV and seasonal influenza are two of the most prevalent causes of respiratory infection in the U.S. In this study, we used weekly positive case reports and genetic surveillance data to characterize the circulation of these viruses in the United States between 2011 and 2019 and a mathematical modeling approach to explore their potential interaction at a regional level.

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Breast cancer (BC) exhibits extensive heterogeneity, complicating personalized treatment. Glycosyl transferases (GTs) are potential biomarkers for cancer treatment. Consensus clustering was performed on GT-related genes (GTRGs) in the The Cancer Genome Atlas Breast Cancer cohort.

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Lower extremity deep vein thrombosis is one of the important complications of spontaneous intracerebral hemorrhage. We aimed to develop a risk assessment model to predict the risk of lower extremity DVT during hospitalization in patients with spontaneous cerebral hemorrhage. The retrospective study began by randomly dividing the data into a training set and a test set in a 7:3 ratio.

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Early vascular lesions are closely associated with the phenotypic switching of vascular smooth muscle cells (VSMCs). Transient receptor potential vanilloid family member 4 (TRPV4) calcium channels are crucial for regulating vascular function. However, whether they contribute to the phenotypic switching of VSMCs remains unknown.

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Although many venom proteins and other parasitic effectors have been identified in various specific systems of parasitoids, key elements that contribute to parasitic success across a broad range of taxa remain largely unexplored. Here, we focus on Leptopilina and conduct a large-scale, multi-omics study to explore common venom proteins for these drosophilid parasitoids. We find that this genus has undergone extensive chromosome rearrangements and a rapid turnover of venom gene repertoires between species.

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Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial inflammatory condition characterized by persistent sinus inflammation and tissue remodeling. Epithelial-derived alarmins, including thymic stromal lymphopoietin (TSLP), interleukin-33 (IL-33), and interleukin-25 (IL-25), are critical mediators that initiate and amplify immune responses in CRSwNP. These alarmins are secreted by stressed or damaged nasal epithelial cells in response to environmental insults, such as allergens, microbial infections, pollutants, and proteases.

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Behavioral fever, a thermoregulatory response in which ectothermic animals seek warmer environments to elevate body temperature and combat parasite infections, is well documented against microparasites. However, its role and mechanisms against macroparasites remain largely unknown. Here, we show that hosts use behavioral fever to defend against parasitoid wasps.

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Background: Post-traumatic epilepsy (PTE) is a common complication following traumatic brain injury (TBI). Early PTE refers to the appearance of seizure symptoms within 7 days of the injury. The glucose-to-potassium ratio (GPR) has emerged as a potential biomarker for predicting Early PTE risk.

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Animals often exhibit increased aggression in response to starvation, while parasites often manipulate host behavior. In contrast, underlying molecular mechanisms for these behavioral changes are mostly unknown. The diamondback moth, , is an agricultural pest that feeds on cruciferous plants as larvae, while is a parasitoid wasp that parasitizes diamondback moth larvae.

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Amis: Chemotherapy-induced hepatotoxicity (CIH) is a significant concern in colorectal cancer (CRC) patients treated with the CAPEOX (capecitabine and oxaliplatin) regimen. Identifying predictive factors for CIH is crucial for clinical management.

Patients And Methods: This study analyzed colorectal tissue (CRT), plasma, and urine samples from CRC patients.

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Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease with varying patterns across regions.

Objective: This study aims to investigate the clinical and histopathological features of CRSwNP in Xizang, a high-altitude region in China.

Materials And Methods: We retrospectively analyzed the histopathological features of CRSwNP patients from Shanghai and Xizang who underwent functional endoscopic sinus surgery (FESS) between 2017 and 2024.

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Background: Ictal examination based on video-based electroencephalography (EEG) is crucial for locating and lateralizing seizures. In this study, we aimed to evaluate the quality of ictal examination in the Comprehensive Epilepsy Center of West China Hospital, Sichuan University, in order to provide information for quality improvement in daily clinical practice.

Methods: Video recordings of 100 patients with epilepsy were retrospectively reviewed.

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Partial differentiation hypothesis is a scenario for interpreting the internal structure of planetesimals and the genetic relationship between chondrites and nonchondrites. However, no petrologic records supporting this hypothesis have been reported yet. Here, we report sulfide replacement textures of melilite and olivine in Ornans-like chondrites, whose occurrences are correlated with the degree of thermal metamorphism of the host chondrites.

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We previously discovered that HOXC6 was the most significantly upregulated gene in right-sided colon cancer compared to left-sided colon cancer according to our previous study; however, the role of HOXC6 in microsatellite instability-high (MSI-H) tumors remains poorly understood. Here, multiple public datasets, and in-house cohorts were used to analyze the differential expression and prognostic role of HOXC6 in colorectal cancer (CRC). Immunohistochemistry and immunofluorescence were performed to evaluate the correlation between HOXC6 expression and M2 macrophage infiltration.

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Background: Previous studies have shown that WZC can increase tacrolimus blood concentration when co-administered. However, limited knowledge exists regarding the pharmacokinetics of both tacrolimus and the bioactive lignans in WZC when administered simultaneously in renal transplantation patients.

Aims: This study aimed to investigate the pharmacokinetics of tacrolimus and multiple bioactive lignans in Wuzhi capsule (WZC) when co-administered with 5 bioactive components in renal transplantation recipients.

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Aims: Rhodotorula mucilaginosa (Rho) has a strong ability to absorb heavy metals. In this study, the influences of fibrous palygorskite (Pal) on fungus-assisted remediation of Cd2+ was investigated.

Methods And Results: Three sets of treatments were performed, i.

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Objectives: To investigate the safety and efficacy of telitacicept in children with immunoglobulin (Ig) A vasculitis nephritis (IgAVN).

Methods: This is a case series of children with biopsy-confirmed IgAVN who received glucocorticoid with or without a second immunosuppressant and presented with urinary protein levels > 0.3 g/day/kg.

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Rodents are known to interact with seed plants in three different ways, including predation in situ, scatter hoarding and larder hoarding of seeds. These behaviours span a spectrum from mutualistic seed dispersal to predation, and they are related to species' and environmental characteristics. We used interaction networks to evaluate the structure and drivers of rodent-seed plant interactions, including geography, phylogeny and traits at continental scales.

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Bumblebees play crucial roles as pollinators in both natural agricultural and ecological systems. Their health and overall fitness are significantly affected by the gut microbiota, which can maintain intestinal homeostasis in hosts by regulating their nutritional metabolism. However, information about the diversity of the gut microbiota and related functional changes during artificial rearing of native species is currently limited.

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Background And Purpose: Intracerebral hemorrhage remains a significant cause of death and disability worldwide, highlighting the urgent need for accurate prognostic assessments to optimize patient management. This study aimed to develop a practical nomogram for risk prediction of poor prognosis after 90 days in patients with intracerebral hemorrhage.

Methods: A retrospective study was conducted on 638 patients with intracerebral hemorrhage in the Second Hospital of Fujian Medical University, China, who were divided into a training set ( = 446) and a test set ( = 192) by random splitting.

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Leptopilina wasps are crucial for biological pest control, particularly against the globally emerging pest Drosophila suzukii. Despite their ecological significance, the genomic basis of host selection and parasitism in this genus remains underexplored. In this study, we assembled a high-quality, chromosome-level genome of Leptopilina myrica, a species collected in Taizhou, Zhejiang Province, China.

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Foraging skills influence food intake and could therefore also play a role in mate choice decision. Previous empirical work has shown that individuals benefit from being in groups that include individuals with a variety of foraging skills as this increases foraging success. This idea, formalized in the skill-pool hypothesis, may extend to mate choice.

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We report a case of acute myeloid leukemia with megakaryoblastic differentiation (AMKL) that developed after an initial B-lymphoblastic leukemia (B-ALL) with low hypodiploidy. Although the AMKL was initially thought either to be a phenotypic change from the original B-ALL or to have arisen as a result of treatment (acute myeloid leukemia, post cytotoxic therapy, AML-pCT [WHO]; AML, therapy related [ICC]), genetic evaluation of both the AMKL and the B-ALL suggest that neither of these considerations was correct. Rather, the AMKL did not harbor the most common genetic hallmark of AML-pCT-rearrangement of and was genetically distinct from the B-ALL.

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The complete mitochondrial genome of Chen, 2023 has been sequenced and analyzed for the first time. The total length we assembled is 15,448 bp, which comprises 13 PCGs, 22 tRNAs, 2 rRNAs, and a CR. The overall nucleotide composition consists of 41.

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