Do rhizosphere microbiomes match root functional traits?

Land plants and microorganisms have developed intricate partnerships during millions of years of coevolution. However, it remains largely unknown how rhizosphere microbiomes align with diverse root functional traits among and within species. We argue that deciphering the bidirectional interactions of root traits with microbial partners is pivotal for understanding rhizosphere processes and belowground ecosystem functioning.

Failure mechanisms and reinforcement of pipe-framed solar greenhouses under snow loads.

Pipe-framed solar greenhouses are susceptible to structural failure under extreme snow loads due to their inherent structural asymmetry. This study investigated the failure mechanisms of a 10 m-span pipe-framed greenhouse and proposed three reinforcement methods (reinforced by one brace, lattice column, and temporary column) to enhance snow resistance. A novel concept of reinforcement efficiency was proposed to optimize retrofitting decisions.

Yeast protein as a fishmeal substitute: impacts on reproductive performance, immune responses, and gut microbiota in two sow hybrids.

Introduction: The persistent African swine fever epidemic has significantly compromised China's swine production. To accelerate production recovery, commercial farms are increasingly adopting retention of two-way backcross sows (Landrace × Yorkshire × Landrace, LLY) for breeding. This study aimed to investigate the effects of yeast protein, an emerging sustainable protein source, on reproductive performance, immune responses, and gut microbiota in two-way crossbred sows (Landrace × Yorkshire, LY) and LLY sows.

Gestational Inulin Supplementation in Low-/High-Fat Sow Diets: Effects on Growth Performance, Lipid Metabolism, and Meat Quality of Offspring Pigs.

This study investigated whether the supplementation of prebiotic inulin to gestating sows programmatically affects offspring growth performance and meat quality while exploring its epigenetic effects through histone acetylation modulation. After mating, sixty multiparous sows (Landrace × Yorkshire; parity 2-3) were assigned to a 2 × 2 factorial arrangement with inulin (0% vs. 1.

Optimizing Root Phenotypes for Compacted Soils: Enhancing Root-Soil-Microbe Interactions.

Soil compaction impedes root growth, reduces crop yields, and threatens global food security and sustainable agriculture. Addressing this challenge requires a comprehensive understanding of root-soil interactions in compacted environments. This review examines key root traits-architectural, anatomical, biochemical, and biomechanical-that enhance plant resilience in compacted soils.

Regulation of maize root growth by local phosphorus availability, sucrose metabolism, and partitioning.

Background And Aims: Understanding how maize roots proliferate in phosphorus (P)-rich soil patches is critical for improving nutrient acquisition and crop productivity. This study explores the mechanisms of root adaptation to heterogeneous P availability, focusing on sucrose metabolism and the role of local P signals.

Methods: A split-root system with chambers of differing Pi concentrations (0 and 500 μM) was used to examine maize root responses.

Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs.

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) has emerged as a promising therapeutic target for cancer treatment. However, the current PIN1 inhibitors have shown limited efficacy in animal models, leaving the question of whether PIN1 is a proper oncologic target still unanswered. By screening a 1 trillion DNA-encoded library (DEL), we identified novel nonacidic compounds.

Exploring the applicability of a multifactor mindfulness scale in the Chinese college context.

The development of a precise and comprehensive mindfulness measurement tool is a compelling area of research due to its lack at present. This study examines the utility of a multifactor mindfulness scale, particularly the Chinese version of the Comprehensive Inventory of Mindfulness Experiences (CHIME), among Chinese college students. Prior to formal testing, 410 subjects completed the CHIME-37, providing feedback for refinement.

Understanding plant-soil interactions underpins enhanced sustainability of crop production.

The Green Revolution transformed agriculture with high-yielding, stress-resistant varieties. However, the urgent need for more sustainable agricultural development presents new challenges: increasing crop yield, improving nutritional quality, and enhancing resource-use efficiency. Soil plays a vital role in crop-production systems and ecosystem services, providing water, nutrients, and physical anchorage for crop growth.

IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer.

Colorectal cancer is a major global health burden, with limited efficacy of traditional treatment modalities in improving survival rates. However, recently advances in immunotherapy has improved treatment outcomes for patients with this cancer. To address the continuing need for improved treatment efficacy, this study introduced a novel tri-specific antibody, IMT030122, that targets EpCAM, 4-1BB, and CD3.

Mechanism of Nicotiflorin in San-Ye-Qing rhizome for anti-inflammatory effect in ulcerative colitis.

Background: The incidence of ulcerative colitis (UC) is on the rise globally and the development of drugs targeting UC is urgent. Finding the target of action of natural products is important for drug discovery, elucidation of drug action mechanism, and disease mechanism. San-Ye-Qing (SYQ), is an ancient herbal medicine, but whether the powder of its rhizome has pharmacological effects against UC and its mechanism of action are not clear.

Association of ACP5 with the tumor immune microenvironment and its role in cell proliferation and metastasis in pancreatic cancer.

Background: Tartrate-resistant acid phosphatase (ACP5) has been implicated in the progression of most malignant tumors, but its role in pancreatic cancer (PC) remained unclear. Thus, this study aimed to elucidate the role and function of ACP5 in PC progression.

Methods: The expression of ACP5 in PC samples was assessed via R programming, TNM plot, and Gene Expression Profiling Interactive Analysis (GEPIA).

RBM12 regulates the progression of hepatocellular cancer via miR-497-5p/CPNE1 Axis.

Background: Hepatocellular Carcinoma (HCC), also called hepatocellular cancer, has emerged as a highly prevalent malignancy globally. By binding to specific RNA via one or more spherical RNA Domains (RBDs) or RNA Motifs (RBMs), RNA Binding Proteins (RBPs) can affect RNA modification, splicing, localization, translation, and stability.

Methods: This paper builds on previous research by further investigating the impact of RBM12 on LC progression.

Phosphorus partitioning contribute to phosphorus use efficiency during grain filling in .

Introduction: Lower phosphorus (P) availability limits crop productivity in agroecosystems. The remobilization of P from the source to the sink organs plays an important role in enhancing the P-utilization efficiency of crops. During the grain filling stage, phosphorus flow to the developing grains, the primary sink, determines crop yield.

Biomass partitioning and ionomics of with high manganese and low phosphorus concentrations.

Knowledge of the ionome of plant organs helps us understand a plant's nutritional status. However, the ionome of Macadamia (Proteaceae), which is an important nut-producing tree, remains unknown. We aimed to characterise the allocation of biomass and nutrient-partitioning patterns in three macadamia genotypes.

Dispositional mindfulness and mental health among Chinese college students during the COVID-19 lockdown: The mediating role of self-compassion and the moderating role of gender.

College students' mental health has been seriously impacted during the global COVID-19 lockdown. There is evidence that dispositional mindfulness is beneficial to mental health. However, few studies have looked at the relationship between dispositional mindfulness and mental health from the standpoint of self-compassion.

Differences in foliar phosphorus fractions, rather than in cell-specific phosphorus allocation, underlie contrasting photosynthetic phosphorus use efficiency among chickpea genotypes.

Although significant intraspecific variation in photosynthetic phosphorus (P) use efficiency (PPUE) has been shown in numerous species, we still know little about the biochemical basis for differences in PPUE among genotypes within a species. Here, we grew two high PPUE and two low PPUE chickpea (Cicer arietinum) genotypes with low P supply in a glasshouse to compare their photosynthesis-related traits, total foliar P concentration ([P]) and chemical P fractions (i.e.

Rhizosphere engineering for sustainable crop production: entropy-based insights.

There is a growing interest in exploring interactions at root-soil interface in natural and agricultural ecosystems, but an entropy-based understanding of these dynamic rhizosphere processes is lacking. We have developed a new conceptual model of rhizosphere regulation by localized nutrient supply using thermodynamic entropy. Increased nutrient-use efficiency is achieved by rhizosphere management based on self-organization and minimized entropy via equilibrium attractors comprising (i) optimized root strategies for nutrient acquisition and (ii) improved information exchange related to root-soil-microbe interactions.

Identification of key genes and infiltrating immune cells among acetaminophen-induced acute liver failure and HBV-associated acute liver failure.

Background: Acute liver failure (ALF) is a life-threatening complication that is relatively uncommon. ALF causes severe hepatocyte damage and necrosis, which can lead to liver dysfunction and even multi-organ failure. A growing body of evidence suggests that immune cell infiltration and some abnormally expressed genes are associated with ALF development.

Validation of rib structural responses under dynamic loadings using different material properties: A finite element analysis.

In this paper, human rib finite element models were created and validated based on finite element simulations. Validation tests were conducted through replicating experimental configurations of ribs under dynamic anterior-posterior bending, and by comparing numerical rib structural responses and fracture locations against experimental data. Human rib cortical bone material properties from different loading modes (tension and compression), strain rates (0.

Ensuring future food security and resource sustainability: insights into the rhizosphere.

Feeding the world's growing population requires continuously increasing crop yields with less fertilizers and agrochemicals on limited land. Focusing on plant belowground traits, especially root-soil-microbe interactions, holds a great promise for overcoming this challenge. The belowground root-soil-microbe interactions are complex and involve a range of physical, chemical, and biological processes that influence nutrient-use efficiency, plant growth and health.