Publications by authors named "Guangyao Hua"

Background: Cardiovascular diseases (CVDs) are a major global health issue, influenced by income level and sleep duration.

Objectives: This study sought to assess the impact of income inequality and sleep duration on CVD outcomes in China and the United Kingdom.

Methods: We analyzed data from the China Kadoorie Biobank (CKB) (n = 486,131) and UK Biobank (UKB) (n = 403,858).

View Article and Find Full Text PDF

Objectives: Aortic aneurysm (AA) is a life-threatening disease with high mortality. Up-to-date, information on AA burden in China is limited, which is required for health-care planning, resource allocation, and disease prevention. This study investigated the burden of AA in China from 1990 to 2021, and then compared it with other G20 countries.

View Article and Find Full Text PDF

Background: Cardiorespiratory fitness (CRF) is a modifiable risk factor for chronic diseases, but its association with depressive symptoms remains unclear, particularly across different populations. We aimed to investigate the link between estimated CRF (eCRF) and incident depressive symptoms among individuals over 50 years old, and to explore potential cross-country variations in this association.

Methods: Data were retrieved from three national cohorts: the Health and Retirement Study (HRS, United States), the English Longitudinal Study of Ageing (ELSA, England), and the China Health and Retirement Longitudinal Study (CHARLS, China).

View Article and Find Full Text PDF

Background: The asymptomatic onset and extremely high mortality rate of aortic aneurysm (AA) highlight the urgency of early detection and timely intervention. The alteration of retinal vascular features (RVFs) can reflect the systemic vascular properties, and be widely used as the biomarker for cardiovascular disease risk prediction. Therefore, we aimed to investigate associations of RVFs with AA and its progression.

View Article and Find Full Text PDF

Background: Retinoblastoma (RB), an aggressive intraocular malignancy, significantly adds to the global disease burden in early childhood. This study offers insights into the global burden of retinoblastoma (RB) in children aged 0-9 years, examining incidence, mortality, and DALYs from 1990 to 2021, across age, sex, location, and SDI levels. It aims to inform health policy, resource allocation, and RB combat strategies.

View Article and Find Full Text PDF

Aims: To systematically clarify the spatiotemporal trends, and age-sex-specific blindness and vision loss (BVL) burden due to high fasting plasma glucose (HFPG) from 1990 to 2019, and project this burden over the next decade.

Materials And Methods: We obtained the number and rate of years lived with disability (YLDs) for the BVL burden attributable to HFPG by age, sex, socio-demographic index (SDI), and location between 1990 and 2019 from the Global Burden of Disease (GBD) 2019 database. The average annual percentage changes (AAPCs) were calculated to assess the temporal trends of HFPG-attributable BVL burden.

View Article and Find Full Text PDF

Background: To assess the burden and change in incidence, death, and disability-adjusted life years (DALYs) for all-cause-specific injuries among children and adolescents in 204 countries and territories between 1990 and 2019.

Materials And Methods: Data were extracted from the Global Burden of Disease, Injury, and Risk Factor Study 2019 (GBD 2019). Global, regional, and country-level age-standardized rate (per 100 000) of incidence (ASRI), mortality (ASRM), and DALYs (ASRD) with 95% uncertainty interval (95% UI) of injuries were estimated by age, sex, socio-demographic index (SDI), and all-cause-specific injuries from 1990 to 2019.

View Article and Find Full Text PDF

Purpose: The risk of cardiovascular disease (CVD) mortality in patients with localized prostate cancer (PCa) by risk stratification remains unclear. The aim of this study was to determine the risk of CVD death in patients with localized PCa by risk stratification.

Patients And Methods: Population-based study of 340,806 cases in the Surveillance, Epidemiology, and End Results (SEER) database diagnosed with localized PCa between 2004 and 2016.

View Article and Find Full Text PDF
Article Synopsis
  • Drug use disorders are a major global public health issue, with updated analyses showing increased prevalence, incidence, deaths, and disability-adjusted life-years (DALYs) over the past three decades.
  • The study focused on four main categories of drug use disorders—opioids, cocaine, amphetamines, and cannabis—across 204 countries from 1990 to 2019, utilizing advanced statistical models for accurate estimates.
  • The findings indicate a rising burden particularly in developed countries, among young males, highlighting the urgent need for improved management programs, effective prevention, and support services to address the escalating demand.
View Article and Find Full Text PDF