Factors Associated with Acceptance of Screening and Knowledge About Dementia in Older Adults in China: A Cross-Sectional Study.

: Dementia is one of the leading causes of disability and dependence among older adults. Early screening may support timely intervention and risk management, contributing to better outcomes at the public health level. However, evidence relating to the factors influencing dementia screening acceptance and knowledge among older adults remains limited.

Evaluating compliance in three-dimensional-printed polymeric vascular grafts compared to human arteries and commercial grafts in a mock circulation loop compliance in three-dimensional-printed polymeric vascular grafts.

Compliance mismatch between native arteries and prosthetic grafts contribute to complications such as neointimal hyperplasia and pseudoaneurysms, leading to reduced graft patency. Three-dimensional (3D) printing offers a promising solution by flexibly customizing mechanical properties using elastic polymers. This study investigates whether 3D-printed polymeric grafts can better replicate native arterial compliance compared with commercial prosthetic grafts.

Effects of donor-specific microvascular anatomy on hemodynamic perfusion in human choriocapillaris.

Evidence from histopathology and clinical imaging suggest that choroidal anatomy and hemodynamic perfusion are among the earliest changes in retinal diseases such as age-related macular degeneration (AMD). However, how inner choroidal anatomy affects hemodynamic perfusion is not well understood. Therefore, we sought to understand the influences of choroidal microvascular architecture on the spatial distribution of hemodynamic parameters in choriocapillaris from human donor eyes using image-based computational hemodynamic (ICH) simulations.

Platelet-to-lymphocyte, neutrophil-to-lymphocyte and lymphocyte-to-monocyte ratios are related to cancer-related fatigue and quality of life in patients with cancer: a cross-sectional study.

Objectives: To explore the association of the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and lymphocyte-to-monocyte ratio (LMR) with cancer-related fatigue (CRF) and quality of life (QOL) in cancer patients.

Design: A cross-sectional study.

Settings: A grade A tertiary hospital in Wuhan, China.

"We are in the forgotten corner!" a qualitative study of experiences and challenges among Chinese older women at the onset of acute myocardial infarction.

Background: Acute myocardial infarction (AMI) is a common and serious cardiovascular disease (CVD) that is one of the leading causes of death among women globally and in China. However, there are sex-associated differences and inequalities in the detection and management of AMI, especially in older people. There is little research demonstrating how challenges and barriers affect older women's help-seeking behavior and health-related procedures in China.

Combined effects of vitamin C and cold atmospheric plasma-conditioned media against glioblastoma via hydrogen peroxide.

Glioblastoma is the most lethal intracranial malignant tumor, for which the five-year overall survival rate is approximately 5%. Here we explored the therapeutic combination of vitamin C and plasma-conditioned medium on glioblastoma cells in culture and as subcutaneous or intracranial xenografts in mice. The combination treatment reduced cell viability and proliferation while promoting apoptosis, and the effects were significantly stronger than with either treatment on its own.

Living experiences of people with advance cancer with low socioeconomic status: A systematic review of qualitative evidence.

Background: The number of patients with advanced cancer is rapidly increasing, and the subgroup of this population with low socioeconomic status has suffered more disease burden than others. However, there is no recent qualitative synthesis of primary research studies into advanced cancer patients with low socioeconomic status.

Objective: To synthesise qualitative research findings into advanced cancer patients' experiences with low socioeconomic status, and then to help provide targeted and effective strategies to improve their quality of life.

Effects of progressive muscle relaxation on health-related outcomes in cancer patients: A systematic review and meta-analysis of randomized controlled trials.

Background And Purpose: Progressive muscle relaxation training (PMRT) has been widely applied to improve the physical and mental health of patients. The aim of this study was to evaluate the effects of PMRT on the symptoms and quality of life (QOL) of cancer patients.

Methods: Nine databases (Web of Science, CENTRAL, PubMed, Embase, CINAHL, OpenGrey, CNKI, Wanfang, and VIP database) were searched to identify randomized controlled trials (RCTs) that assessed the effects of PMRT on health-related outcomes for cancer patients.

Knowledge of enhanced recovery after surgery and influencing factors among abdominal surgical nurses: a multi-center cross-sectional study.

Enhanced recovery after surgery (ERAS) protocols are well established. Evidence describing nurses' knowledge of ERAS is limited.: To assess surgical nurses' knowledge of ERAS and identify factors that correlate with knowledge level.

Human Encephalitis Caused by Pseudorabies Virus in China: A Case Report and Systematic Review.

Pseudorabies virus (PRV) is a common pathogen found in pigs. The pathogenicity of PRV in humans is under researched and there are few confirmed cases of PRV infections in humans, which has led to a lack of clinical consensus. We presented a case of viral encephalitis caused by PRV in China.

A new noninvasive and patient-specific hemodynamic index for the severity of renal stenosis and outcome of interventional treatment.

Renal arterial stenosis (RAS) often causes renovascular hypertension, which may result in kidney failure and life-threatening consequences. Direct assessment of the hemodynamic severity of RAS has yet to be addressed. In this work, we present a computational concept to derive a new, noninvasive, and patient-specific index to assess the hemodynamic severity of RAS and predict the potential benefit to the patient from a stenting therapy.

The Predictive Ability of the Renal Resistive Index and Its Relationship to Duplex Ultrasound Waveform Propagation in the Aorta and Renal Arteries.

Background: The objective is to investigate whether calculating the PPI (Pulse Pressure Index) and the RRI (Renal Resistive Index) using routinely collected Duplex ultrasound waveforms data obtained from the aorta and renal artery correlates and predicts renal function, and determine whether RRI is affected by the presence of a renal artery stenosis.

Methods: The records of 965 patients were evaluated. The RRI or pulsatility index of the aorta, renal artery, hilum, cortex, and medulla were measured with concurrent glomerular filtration rate GFR, Cr, PPI, and HR measurements, among which 75 patients had a 24-hour urine measured for CrCl, and 32 patients had aortic pulse pressure index (API) calculated from the central aortic pressure measured with applanation tonometry.

Volumetric lattice Boltzmann method for wall stresses of image-based pulsatile flows.

Image-based computational fluid dynamics (CFD) has become a new capability for determining wall stresses of pulsatile flows. However, a computational platform that directly connects image information to pulsatile wall stresses is lacking. Prevailing methods rely on manual crafting of a hodgepodge of multidisciplinary software packages, which is usually laborious and error-prone.

Living experiences of patients with advanced cancer with low socioeconomic status: protocol for a systematic review of qualitative evidence.

Introduction: The number of patients with advanced cancer is rapidly increasing, and the disease burden among those with low socioeconomic status (SES) has accordingly become a global concern. Low SES can adversely impact patients with advanced cancer. The purpose of this systematic review is to shed light on the life experiences of patients with advanced cancer with low SES to help provide targeted and effective strategies to improve their quality of life.

Additional Value of Non-contrast Chest CT in the Prediction of Adverse Cardiovascular Events in Patients With Novel Coronavirus Disease 2019 (COVID-19).

Coronavirus disease 2019 (COVID-19) has outbroken in China and subsequently spread worldwide since the end of 2019. Chest computed tomography (CT) plays an important role in the diagnosis of lung diseases, but its value in the diagnosis of cardiac injury remains unknown. We enrolled 241 consecutive hospitalized patients (aged 61 ± 16 years, 115 males) with laboratory-confirmed COVID-19 at Renmin Hospital of Wuhan University from January 11 to March 2, 2020.

Effect of Dexmedetomidine on The Neuroglobin Expression in Elderly Patients With Minimally Invasive Coronary Artery Bypass Graft Surgery.

Background: To study the effect of dexmedetomidine (Dex) on the expression of Neuroglobin (Ngb) and postoperative cognitive function in elderly patients undergoing minimally invasive coronary artery bypass surgery.

Methods: Forty patients, who underwent elective minimally invasive off-pump coronary artery bypass grafting in our hospital from January 2018 to December 2019, were randomly divided into the Dex group (N = 20) and control group (N = 20). Venous blood samples were taken to determine the expression level of Ngb in both groups.

Regulatory role of microRNA-320 during off-pump coronary artery bypass grafting with dexmedetomidine adjunct anesthesia.

The present study investigated the effects of dexmedetomidine on the expression level of microRNA-320 (miR-320) and neuroglobin (NGB) in patients undergoing off-pump coronary artery bypass grafting (OPCABG). A total of 40 patients undergoing OPCABG were recruited and randomly divided into the dexmedetomidine and normal saline groups (treated before anesthesia), respectively. The NGB levels in the blood samples before and after surgery were analyzed and compared.

Computational modeling of intraocular drug delivery supplied by porous implants.

New and efficient drug delivery to the posterior part of the eye is a growing health necessity worldwide. Current treatment of eye diseases, such as age-related macular degeneration (AMD), relies on repeated intravitreal injections of drug-containing solutions. Such a drug delivery has major drawbacks including short drug life, significant medical service, and high medical cost.

Psychometric testing of the Chinese version of Self-Care of Coronary Heart Disease Inventory.

Aim: To psychometrically test the Chinese version of Self-Care of Coronary Heart Disease Inventory.

Background: Self-care is a significant step to impede the progression of coronary heart disease and serves as the primary outcome in self-care interventions. In China, however, no instrument is available to measure self-care in patients with coronary heart disease.

Combination of metformin and cold atmospheric plasma induces glioma cell death to associate with c-Fos.

Glioma is the most common type of brain cancer. Chemotherapy combination with surgery and radiotherapy is a standard treatment for patients. Although there are many advances in glioma therapy, the prognosis of glioma patients has not significantly been improved over the past decades.

General power-law temporal scaling for unequal-size microbubble coalescence.

We systematically study the effects of liquid viscosity, liquid density, and surface tension on global microbubble coalescence using lattice Boltzmann simulation. The liquid-gas system is characterized by Ohnesorge number Oh≡η_{h}/sqrt[ρ_{h}σr_{F}] with η_{h},ρ_{h},σ, and r_{F} being viscosity and density of liquid, surface tension, and the radius of the larger parent bubble, respectively. This study focuses on the microbubble coalescence without oscillation in an Oh range between 0.

The Negative Emotions Due to Chronic Illness Screening Test (NECIS): Construct Validity in Patients with Coronary Artery Disease in Mainland China.

Objective: Patients with coronary artery disease (CAD) are susceptible to the negative emotion and its adverse influence on the disease prognosis. It is of great necessity to have a simple measurement to timely assess negative emotions in patients with CAD. The Negative Emotions due to Chronic Illness Screening Test (NECIS) is a newly developed tool to measure negative emotions.

The Chinese version of the Coronary Artery Disease Education Questionnaire-II (CADEQ-II): translation and validation.

Objectives: It is necessary to assess disease-related knowledge in patients with coronary artery disease (CAD) for tailored patient education; however there is a lack of a well-validated measurement in China. The objective of this study was to translate and validate a Chinese version of the Coronary Artery Disease Education Questionnaire-II (CADEQ-II).

Methods: The Chinese version of CADEQ-II was translated and culturally adapted.

Effectiveness, safety and comfort of StatLock securement for peripherally-inserted central catheters: A systematic review and meta-analysis.

In this systematic review and meta-analysis, we evaluated the effectiveness, safety and comfort of StatLock for the securement of peripherally-inserted central catheters. PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, WanFang Database, and China Science and Technology Journal Database were searched. Randomized, controlled trials comparing StatLock with tape or suture on the performance of securing peripherally-inserted central catheters were selected.

Mass-conserved volumetric lattice Boltzmann method for complex flows with willfully moving boundaries.

In this paper, we develop a mass-conserved volumetric lattice Boltzmann method (MCVLBM) for numerically solving fluid dynamics with willfully moving arbitrary boundaries. In MCVLBM, fluid particles are uniformly distributed in lattice cells and the lattice Boltzmann equations deal with the time evolution of the particle distribution function. By introducing a volumetric parameter P(x,y,z,t) defined as the occupation of solid volume in the cell, we distinguish three types of lattice cells in the simulation domain: solid cell (pure solid occupation, P=1), fluid cell (pure fluid occupation, P=0), and boundary cell (partial solid and partial fluid, 0 View Article and Find Full Text PDF