Publications by authors named "Giovanni Salzano"

this pilot study aimed to evaluate the diagnostic accuracy of ChatGPT-4o in analyzing oral mucosal lesions from clinical images. : a total of 110 clinical images, including 100 pathological lesions and 10 healthy mucosal images, were retrieved from Google Images and analyzed by ChatGPT-4o using a standardized prompt. An expert panel of five clinicians established a reference diagnosis, categorizing lesions as benign or malignant.

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: The aim of our study was to evaluate clinical outcomes in patients with small pleomorphic adenoma (PA) after extracapsular dissection (ED) versus superficial parotidectomy (SP). : Following the PRISMA guidelines, a systematic review covering the years from 1950 to 2025 was conducted using the Pubmed/MEDLINE, Cochrane Library, Scopus, Ovid MEDLINE and Embase databases. A single-arm meta-analysis was performed to evaluate intraoperative capsular rupture, recurrence, transient and permanent facial nerve palsy, Frey's syndrome, salivary fistula, seroma and hematoma of patients who underwent ED vs.

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This systematic review and meta-analysis evaluates the surgical, functional, and aesthetic outcomes of scapular free flaps in maxillary reconstruction. The primary objective is to assess early surgical complications, fistula formation, donor site morbidity, dental restoration, normal dietary intake, aesthetic compromise, and eye-related issues. Secondary objectives include total free flap necrosis, the need for revision procedures, and functional performance of the upper limb.

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Objectives: This manuscript reviews advancements in oral and maxillofacial surgery, encompassing minimally invasive techniques, innovations in implant dentistry, regenerative medicine, innovations in temporomandibular joint, and novel methodologies in salivary gland surgery.

Methods: A comprehensive analysis of recent developments in the field is presented, focusing on the integration of new technologies and biological therapies. Emphasis is placed on minimally invasive procedures, virtual surgical planning with CAD/CAM and 3D printing, implant design and placement innovations, and regenerative approaches.

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Currently, diagnosing salivary gland tumors in their early stages presents significant challenges. This paper aims to outline a feasibility analysis of a novel approach utilizing advanced nanophotonic sensors and AI to address these diagnostic issues. The proposed approach integrates new nanophotonic sensors to tackle the complexities encountered in the early detection of salivary gland tumors.

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Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by joint inflammation and skin lesions. Recent research has underscored the critical role of gut microbiota-comprising bacteria, fungi, viruses, and archaea-in the pathogenesis and progression of PsA. This narrative review synthesizes the latest findings on the influence of gut microbiota on PsA, focusing on mechanisms such as immune modulation, microbial dysbiosis, the gut-joint axis, and its impact on treatment.

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Background/objectives: Oral cavity carcinomas (OCCs) represent roughly 50% of all head and neck cancers. The risk of occult neck metastases for early-stage OCCs ranges from 15 to 35%, thus the need to develop tools that can support the diagnosis detecting these neck metastases. Inflammatory biomarkers and perineural and lympho-vascular invasion are emerging as effective in this field.

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Ocular trauma remains a significant cause of vision loss, often resulting from penetrating injuries caused by foreign bodies such as glass, metal, wood, and other materials. Despite advancements in ocular surgery, retained intraorbital foreign bodies may lead to delayed complications if not promptly identified and managed. We present the case of a 59-year-old male who reported severe right eye pain and diplopia seven years following a work-related facial injury.

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Myomucosal cheek flaps are currently considered the main reconstructive option for small to moderate oral cavity defects. Many reconstructive techniques following the resectioning of oral tongue squamous cell carcinoma (OTSCC) have been proposed over the years. We report a case of OTSCC treated surgically and reconstructed with Bozola flap, analyzing the advantages and disadvantages of this surgical technique.

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Eyelid defects, particularly those affecting the medial canthus, present intricate challenges for reconstructive surgeons due to the complex anatomy and functional significance of the region. This article presents our management of an 87-year-old patient with medial canthal basal cell carcinoma, highlighting the successful management of such defects through a single-stage reconstruction technique involving a skin graft supported by a synthetic dermal matrix (MatriDerm). The utilization of this approach resulted in favorable outcomes, including clear margins on histological examination and stable esthetic results at 1-year follow-up, emphasizing its efficacy in addressing medial canthal defects secondary to basal cell carcinoma excision.

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Severe atrophy in isolated posterior maxillary sectors poses challenges for dental rehabilitation, especially in partially dentate patients where traditional graftless techniques are unsuitable. This study retrospectively analyzed the outcomes of sectional rehabilitation in 16 consecutive patients with Cawood and Howell class V to VI atrophy treated with 21 custom fabricated subperiosteal implants. Patients were followed for a median of 36 months (interquartile range: 24 to 48).

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Objective: This study aims to evaluate the outcomes of Wendler's glottoplasty in an all-Italian cohort of transgender women, focusing on its efficacy, safety, and impact on patient satisfaction.

Study Design: Retrospective observational study.

Methods: The study was conducted on 10 Italian transgender women aged 25-40 years who underwent Wendler's glottoplasty at the University of Salerno from January 2020 to December 2022.

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Background: The aim of the current study was to identify predictors of erectile dysfunction (ED) and obstructive sleep apnea syndrome (OSAS) in male participants at Italian web-survey.

Methods: A cross-sectional web-based survey was administered via Google Forms between July 17 and October 31, 2022, among Italian participants. The erectile function and the excessive daytime sleepiness were measured through the International Index of Erectile Function - 5 (IIEF5) and Epworth Sleepiness Scale (ESS), respectively.

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Objective: The purpose of this study has been to analyze retrospectively the clinical records of patients admitted to a single Maxillofacial Surgery center in Northern Italy, evaluating the epidemiological differences during the different phases of the SARS-CoV-2 pandemic.

Materials And Methods: The retrospective study included patients who had undergone surgery for facial bone fractures at the between February 23, 2020, and February 23, 2022. According to the date of admission, all the data were stratified into four chronological periods representing the four different phases of the SARS-CoV-2 pandemic in Italy in terms of restriction: pre-pandemic, first wave, partial restrictions and post-pandemic groups.

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Objective: This study aims to evaluate the impact of prompt construction on the quality of artificial intelligence (AI) chatbot responses in the context of head and neck surgery.

Study Design: Observational and evaluative study.

Setting: An international collaboration involving 16 researchers from 11 European centers specializing in head and neck surgery.

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Laryngeal metastasis from a primitive distant cancer is a rare finding in clinical practice. In this paper is presented the case of a 63-year-old patient treated for lung adenocarcinoma metastasis in the supraglottic larynx. A review of literature suggests how the treatment of this kind of case is not unique.

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This study evaluates the quality and readability of informed consent documents generated by AI platforms ChatGPT-4 and Bard Gemini Advanced compared to those written by a first-year oral surgery resident for common oral surgery procedures. The evaluation, conducted by 18 experienced oral and maxillofacial surgeons, assessed consents for accuracy, completeness, readability, and overall quality. ChatGPT-4 consistently outperformed both Bard and human-written consents.

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Checkpoint inhibitors (ICIs) have demonstrated substantial efficacy in the treatment of numerous solid tumors, including head and neck cancer. Their inclusion in the therapeutic paradigm in metastatic lines of treatment has certainly improved the outcomes of these patients. Starting from this assumption, numerous studies have been conducted on ICIs in other earlier disease settings, including studies conducted in patients in neoadjuvant settings.

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Objective: The aim of this study was to investigate the correlation among inflammatory biomarkers, such as the systemic immune-inflammation index (SII), the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), and the recurrence of pleomorphic adenomas (PAs).

Study Design: This was a retrospective multicenter study. Six hundred eight patients diagnosed with PA and treated by tumor enucleation were included in the analyses.

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Multifragmentary and displaced zygomaticomaxillary complex (ZMC) fractures are often a challenge for the maxillofacial surgeon. The aim of this study was to evaluate the improved performance in the management of patients with tripod fracture of the orbito-zygomaticomaxillary complex, using two different methods of virtual surgical planning - virtual reduction and mirroring - compared with traditional management. A cohort of 60 patients was selected and divided into three groups, each consisting of 20 individuals.

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Article Synopsis
  • The study investigated the impact of standing electric scooters on maxillofacial injuries in Italy, collecting data from 10 maxillofacial surgery departments over a three-year period from January 2020 to December 2023.
  • A total of 79 patients were analyzed, with an average age of 31; notable findings included that 19% had elevated blood alcohol levels and only one patient wore a helmet during the accident.
  • The most common injuries were fractures in the middle third of the face, particularly the orbito-malar-zygomatic complex and multifocal mandibular fractures, highlighting the complex nature of injuries and high likelihood of post-surgical complications.
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Article Synopsis
  • Doctors have found it hard to fix broken jaws with traditional surgery, but using virtual planning is helping a lot.
  • In a study, 30 patients were divided into two groups: one used virtual planning and the other used the old method.
  • The group with virtual planning had fewer mistakes and took less time for surgery compared to the traditional group.
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