Predicting the occurrence of probable sarcopenia in middle-aged and elderly patients with coronary artery disease: development and validation of a clinical model.

The objective of this research was to identify the factors contributing to the decline in handgrip strength among middle-aged and elderly individuals with this condition. In addition, an algorithmic model for the detection of probable sarcopenia will be developed. This research encompassed the collection and evaluation of fundamental data, laboratory indicators, body composition metrics, and lifestyle factors.

Eye movement predictors of hazard response performance in train drivers under different speed conditions.

Foreign objects on railroads contribute to railway accidents. Train driving heavily relies on visual prowess. Drivers must quickly identify and react to these hazards, capabilities that directly impact the safety and efficiency of train operations.

Engineering the mechanical characteristics of regenerated silk fibroin materials: the impact of chemical and physical modification strategies.

In this study, an in-depth exploration was conducted on the mechanical properties of regenerated silk fibroin (RSF) materials through diverse processing modalities, encompassing wet pressing, humidity treatments at varying levels, and the incorporation of plasticizers. Notably, these approaches induced substantial modifications in the mechanical properties of RSF materials. The elastic strength of RSF exhibited a wide range, from 12.

Disordered and Conductive Chiral Spin-Selective Strategy to Enhance Small-Molecule-Based Spintronic Application.

Chiral materials, which can manipulate the electron spin by the chiral-induced spin selectivity (CISS) effect without involving the complicated magnetic components, exhibits great potentials in low-cost spin optoelectronics. However, ideal CISS usually requires a relatively ordered and conductive (or insulated but ultrathin) chiral layer, which contradicts the disordered-packing and high-impedance characteristics of chiral molecules, preventing the direct application of most chiral molecules for CISS and increasing the difficulty to prepare chiral spin-selective layers. Here, a general disordered and conductive chiral molecular strategy is proposed to simply construct the small-molecule-based spin polarizer.

The growth performance in different seasons of Homatula variegata (Dabry de Thiersant, 1874) in Northern Guizhou, China.

To provide knowledge on growth performance and data that are helpful for resource assessment of Homatula variegata (Dabry de Thiersant, 1874) living in northern Guizhou, China, the current study focused on the length-weight relationship (LWR), the growth pattern, the condition factor (CF), as well as the relationship between muscle metabolomics and growth in H. variegata. A total of 135 H.

Corrigendum: Epidemiological analysis of turner syndrome in children aged 0-14 years: global, regional, and national perspectives (1990-2021).

[This corrects the article DOI: 10.3389/fendo.2025.

Secondary Hypertension in Children-Identifying and Investigating at Risk Children.

Purpose Of Review: We aim to review the most recent literature on demographic features and diagnostic workup of children with secondary hypertension, in order to provide a framework for health providers to determine which hypertensive pediatric patients warrant further investigation for secondary causes. By highlighting the utility of various diagnostic investigations, we aim to minimize unnecessary testing burden.

Recent Findings: A recent meta-analysis revealed that hypertensive children and adolescents with any of the following features were at increased risk of secondary hypertension: < 6 years of age, history of prematurity, family history of secondary hypertension, body mass index (BMI) < 10th percentile.

Epidemiological analysis of turner syndrome in children aged 0-14 years: global, regional, and national perspectives (1990-2021).

Background: Turner syndrome (TS), a chromosomal disorder (45, X) affecting approximately 1 in 2,000 female births, results in multisystem morbidity. This study aims to report global trends in the prevalence and disability-adjusted life years (DALYs) of childhood TS from 1990 to 2021.

Methods: This study analyzed the prevalence and DALYs of TS in children aged 0-14 years using data from the Global Burden of Disease (GBD) database.

Association of uric acid/high-density lipoprotein cholesterol ratio (UHR) with depression risk in US adults: A cross-sectional study.

Background: The uric acid/high-density lipoprotein cholesterol ratio (UHR) is a new indicator of inflammation and metabolism that has been found to be strongly associated with several chronic diseases. However, the relationship between the UHR and depression has not been studied to date.

Methods: The study included a total of 16,920 participants aged 20 years and older from NHANES 2005-2018.

Design of a high-performance infrared birefringent crystal BaHgPSe a low-dimensional motif intercalation strategy.

The development of birefringent materials, especially infrared (IR) birefringent crystals, has been limited by conflicting microstructural requirements, such as broad transmission range, wide band gap, and large birefringence. In this work, we propose a "low-dimensional motif intercalation" strategy for designing high-performance birefringent materials. Utilizing the layered selenophosphorus BaPSe as a prototype compound, a novel IR birefringent crystal BaHgPSe with enhanced birefringence was successfully synthesized by the intercalation of the linear [HgSe] moieties, while the outstanding optical properties such as wide band gap and long IR cutoff were maintained.

Association between O-GlcNAc transferase activity and major adverse cardiovascular events: findings from the China PEACE-MPP cohort.

Background: The O-GlcNAc transferase (OGT) levels are closely related to the O-GlcNAcylation of proteins and are also associated with cardiovascular disease. This study explored the association between OGT activity and major adverse cardiovascular events (MACEs) in patients with high cardiovascular disease risk. This post hoc study included patients from the China PEACE-MPP study in Yi Wu, Zhejiang Province, between 2014 and 2015.

Analysis of global trends in acute lymphoblastic leukemia in children aged 0-5 years from 1990 to 2021.

Background: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.

Methods: Data were sourced from the Global Burden of Disease study.

Origin and de novo domestication of sweet orange.

Sweet orange is cultivated worldwide but suffers from various devastating diseases because of its monogenetic background. The elucidation of the origin of a crop facilitates the domestication of new crops that may better cope with new challenges. Here we collected and sequenced 226 citrus accessions and assembled telomere-to-telomere phased diploid genomes of sweet orange and sour orange.

Exploring the role of curcumin in mitigating oxidative stress to alleviate lipid metabolism disorders.

Lipid metabolism plays a crucial role in maintaining homeostasis and overall health, as lipids are essential molecules involved in bioenergetic processes. An increasing body of research indicates that disorders of lipid metabolism can contribute to the development and progression of various diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD), diabetes mellitus, atherosclerosis, and cancer, potentially leading to poor prognoses. The activation of the oxidative stress pathway disrupts lipid metabolism and induces cellular stress, significantly contributing to metabolic disorders.

Overexpression of the Vitis amurensis Ca-binding protein gene VamCP1 in Arabidopsis thaliana and grapevine improves cold tolerance.

Calcium ions (Ca) are important second messengers and are known to participate in cold signal transduction. In the current study, we characterized a Ca-binding protein gene, VamCP1, from the extremely cold-tolerant grape species Vitis amurensis. VamCP1 expression varied among organs but was highest in leaves following cold treatment, peaking 24 h after treatment onset.

Factors related to the progression of chronic obstructive pulmonary disease: a retrospective case-control study.

Objectives: To explore the factors related to the progression of chronic obstructive pulmonary disease (COPD).

Methods: 80 COPD patients treated between January 2020 and December 2022. The patients' pulmonary functions at their first hospital admission were categorized into four groups: Grade I, Grade II, Grade III and Grade IV.

Interplays of Dietary Fat with BMI and rs324420 on HDL-C in Gender-Dependent Manner in Adolescents.

The present study was to explore relationship between serum lipid profiles and the polymorphism of rs324420 at fatty acid amide hydrolase (FAAH) gene ( rs324420) and its confounders in Chinese adolescents. Serum lipids, glucose, and insulin levels were assessed using routine methods in a cohort of 708 high school students. Dietary intake was investigated by 3-day diet records, and intakes of protein, fat, and carbohydrate were calculated.

Enhancing Open-Space Gas Detection Limit: A Novel Environmentally Adaptive Infrared Temperature Prediction Method for Uncooled Spectroscopy.

Gas cloud imaging with uncooled infrared spectroscopy is influenced by ambient temperature, complicating the quantitative detection of gas concentrations in open environments. To solve the aforementioned challenges, the paper analyzes the main factors influencing detection errors in uncooled infrared spectroscopy gas cloud imaging and proposes a temperature correction method to address them. Firstly, to mitigate the environmental effects on the radiative temperature output of uncooled infrared detectors, a snapshot-based, multi-band infrared temperature compensation algorithm incorporating environmental awareness was developed.

Geological model calibration based on gradual deformation and connectivity function.

The connectivity is an important feature of the reservoir geological heterogeneity that effects fluid flow responses. In geostatistical modeling, random realizations are generated to describe reservoir heterogeneities. But these realizations do not necessarily honor connectivity data.

In situ synthetic C encapsulated δ-MnO with O vacancies: a versatile programming in bio-engineering.

In this study, we successfully synthesized a δ-MnO cathode with O vacancies, encapsulated by C derived from pyromellitic acid, using a facile hydrothermal method followed by annealing in an Ar atmosphere. The cathode's structural stability and charge transfer kinetics are enhanced by inhibiting the formation of the by-product ZnSO(OH)·4HO, regulating the Mn valence state, and suppressing the Jahn-Teller effect through the synergy of C encapsulation and O vacancies. This results in remarkable electrochemical performance, including a large capacity of 421.

Temperature and Ultrasound-Responsive Nanoassemblies for Enhanced Organ Targeting and Reduced Cardiac Toxicity.

Background: Biocompatible nanocarriers are widely employed as drug-delivery vehicles for treatment. Nevertheless, indiscriminate drug release, insufficient organ-specific targeting, and systemic toxicity hamper nanocarrier effectiveness. Stimuli-responsive nano-sized drug delivery systems (DDS) are an important strategy for enhancing drug delivery efficiency and reducing unexpected drug release.

Transcriptional Landscape of Cotton Roots in Response to Salt Stress at Single-cell Resolution.

Increasing soil salinization has led to severe losses of plant yield and quality. Thus, it is urgent to investigate the molecular mechanism of the salt stress response. In this study, we took systematically analyzed cotton root response to salt stress by single-cell transcriptomics technology; 56,281 high-quality cells were totally obtained from 5-days-old lateral root tips of Gossypium arboreum under natural growth and different salt-treatment conditions.

Correlation of exercise blood pressure levels with concomitant cardiovascular disease.

Hypertension is a fatal but preventable risk factor for cardiovascular disease and an important cause of death from cardiovascular disease. Exercise training has a definite clinical effect on blood pressure control. However, inappropriate exercise is ineffective and may also cause disease.