Meta-anlaysis of Internet-based Behavior Therapy for Tic Disorder.

Introduction: Tourette syndrome and chronic tic disorders are neurodevelopmental disorders characterized by involuntary motor and vocal tics, often beginning in childhood and causing significant distress. While medication and behavioral therapies are established treatments, chronic use of medication can cause side effects, and behavioral therapy faces limited provider availability and geographic barriers. Internet-based behavioral interventions are emerging as alternatives to improve treatment accessibility.

Efficacy of non-invasive brain stimulation in reducing craving in patients with alcohol use disorder: systematic review and meta-analysis.

Background: Craving plays a central role in reinforcing alcohol use disorder (AUD), and non-invasive brain stimulation (NIBS) has shown potential as a therapeutic intervention in AUD. We aim to evaluate the efficacy and safety following the application of NIBS in patients with AUD.

Methods: A search of the PubMed, EMBASE, Cochrane Library and PsycINFO databases for articles published up to June 30, 2024 using predefined search terms identified a total of 20 randomized controlled trials (RCTs) and 22 units.

Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo-Phototronics.

The emergence of two-dimensional (2D) materials has catalyzed significant advancements in the fields of piezotronics and piezo-phototronics, owing to their exceptional mechanical, electronic, and optical properties. This review provides a comprehensive examination of key 2D piezoelectric and piezo-phototronic materials, including transition metal dichalcogenides, hexagonal boron nitride (h-BN), and phosphorene, with an emphasis on their unique advantages and recent research progress. The underlying principles of piezotronics and piezo-phototronics in 2D materials is discussed, focusing on the fundamental mechanisms which enable these phenomena.

Dual-Targeted adversarial example in evasion attack on graph neural networks.

This study proposes a novel approach for generating dual-targeted adversarial examples in Graph Neural Networks (GNNs), significantly advancing the field of graph-based adversarial attacks. Unlike traditional methods that focus on inducing specific misclassifications in a single model, our approach creates adversarial samples that can simultaneously target multiple models, each inducing distinct misclassifications. This innovation addresses a critical gap in existing techniques by enabling adversarial attacks that are capable of affecting various models with different objectives.

Experimental and numerical investigation on the reinforced concrete boundary beam-wall system subjected to axial compression.

This paper proposes a reinforced concrete (RC) boundary beam-wall system that requires less construction material and a smaller floor height compared to the conventional RC transfer girder system. The structural performance of this system subjected to axial compression was evaluated by performing a structural test on four specimens of 1/2 scale. In addition, three-dimensional nonlinear finite element analysis was also performed to verify the effectiveness of the boundary beam-wall system.

Structural performance of the concrete-filled tube column with internal triangular units subjected to axial compression.

This study introduces a novel concrete-filled tube (CFT) column system featuring a steel tube comprised of four internal triangular units. The incorporation of these internal triangular units serves to reduce the width-thickness ratio of the steel tube and augment the effective confinement area of the infilled concrete. This design enhancement is anticipated to result in improved structural strength and ductility, contributing to enhanced overall performance and sustainability.

Spring protistan communities in response to warming in the northeastern East China Sea.

The northeastern East China Sea is a highly dynamic marine ecosystem influenced by seasonally varying water mass properties. However, despite being among the world's fastest-warming ocean, there has been limited investigation into the impacts of warming on protistan communities. We collected seawater from two stations (E42 and E46) with different natural protist communities and environmental attributes to investigate the acclimation of the two communities to artificially elevated temperatures (ambient T, +2, and +4 °C).

Incidence of colonoscopy-related perforation and risk factors for poor outcomes: 3-year results from a prospective, multicenter registry (with videos).

Background And Aims: Perforation is a life-threatening adverse event of colonoscopy that often requires hospitalization and surgery. We aimed to prospectively assess the incidence of colonoscopy-related perforation in a multicenter registry and to analyze the clinical factors associated with poor clinical outcomes.

Methods: This prospective observational study was conducted at six tertiary referral hospitals between 2017 and 2020, and included patients with colonic perforation after colonoscopy.

Evidence of familial confounding of the association between cannabis use and cerebellar-cortical functional connectivity using a twin study.

Cerebellar-cortical resting-state functional connectivity (rsFC) has been reported to be altered in cannabis users. However, this association may be due to genetic and environmental confounding rather than a causal relationship between cannabis use and changes in rsFC. In this co-twin control study, linear mixed models were used to assess relationships between the number of lifetime cannabis uses (NLCU) and age of cannabis onset (ACO) with cerebellar-cortical rsFC.

Cerebellar Structure and Function in Autism Spectrum Disorder.

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by early-onset repetitive behaviors, restricted interests, sensory and motor difficulties, and impaired social interactions. Converging evidence from neuroimaging, lesion and postmortem studies, and rodent models suggests cerebellar involvement in ASD and points to promising targets for therapeutic interventions for the disorder. This review elucidates understanding of cerebellar mechanisms in ASD by integrating and contextualizing recent structural and functional cerebellar research.

Cerebellar Activation Deficits in Schizophrenia During an Eyeblink Conditioning Task.

The cognitive dysmetria theory of psychotic disorders posits that cerebellar circuit abnormalities give rise to difficulties coordinating motor and cognitive functions. However, brain activation during cerebellar-mediated tasks is understudied in schizophrenia. Accordingly, this study examined whether individuals with schizophrenia have diminished neural activation compared to controls in key regions of the delay eyeblink conditioning (dEBC) cerebellar circuit (eg, lobule VI) and cerebellar regions associated with cognition (eg, Crus I).

Altered cerebellar-cortical resting-state functional connectivity in cannabis users.

Background: Cannabis use has been associated with abnormalities in cerebellar mediated motor and non-motor (i.e. cognition and personality) phenomena.

Gastric Angiolipoma Resected with Endoscopic Submucosal Dissection.

Angiolipoma is a benign fatty neoplasm that has components of proliferating blood vessels. These types of lesions commonly occur in the subcutaneous tissue of the limbs and trunk. Angiolipoma in the gastrointestinal tract is extremely rare, and the final diagnosis generally depends on histological examination of the excised biopsy.

Beneficial effects of weekend catch-up sleep on metabolic syndrome in chronic short sleepers.

Objectives: Short sleep duration has been known to be related to metabolic syndrome (MetS) . The aim of this study was to investigate the beneficial effects of weekend catch-up sleep (WCUS) on MetS in the Korean middle-aged population.

Methods: For this cross-sectional study, 1,812 participants aged 35-60 years were selected from the 2016-2018 Korean National Health and Nutrition Examination Survey (mean age 46.

Investigating cerebellar neural function in schizophrenia using delay eyeblink conditioning: A pilot fMRI study.

There is accruing evidence of cerebellar abnormalities in individuals with schizophrenia as measured by performance on a variety of tasks believed to be dependent on cerebellar integrity, including delay eyeblink conditioning. There is also evidence of cerebellar dysfunction on a neural level in schizophrenia from both task-based and resting state neuroimaging studies, however few studies have examined cerebellar neural function while the cerebellum is directly recruited in individuals with schizophrenia. In the current pilot study, we examined neural activity during an explicitly cerebellar task in individuals with schizophrenia or schizoaffective disorder and non-psychiatric controls.

Comparison of different types of covered self-expandable metal stents for malignant colorectal obstruction.

Background: Stent migration is one of the main drawbacks of covered self-expandable metal stent (SEMSs), occurring in up to 40% of malignant colorectal obstruction management cases. Various types of covered SEMSs have been developed to reduce this risk. We aimed to compare the effectiveness and complication rates of the flare-type covered SEMS (Flare) with those of the double-layered covered SEMS (ComVi).

Rich-club in the brain's macrostructure: Insights from graph theoretical analysis.

The brain is a complex network. Growing evidence supports the critical roles of a set of brain regions within the brain network, known as the brain's cores or hubs. These regions require high energy cost but possess highly efficient neural information transfer in the brain's network and are termed the rich-club.

Cerebellar-cortical dysconnectivity in resting-state associated with sensorimotor tasks in schizophrenia.

Abnormalities of cerebellar function have been implicated in the pathophysiology of schizophrenia. Since the cerebellum has afferent and efferent projections to diverse brain regions, abnormalities in cerebellar lobules could affect functional connectivity with multiple functional systems in the brain. Prior studies, however, have not examined the relationship of individual cerebellar lobules with motor and nonmotor resting-state functional networks.

Morphological advantages of endoscopic treatment in obstructive chronic pancreatitis.

Background: and study aims: Chronic pancreatitis is associated with recurrent or persistent abdominal pain over the course of the disease. Ductal hypertension showing obstructed and dilated pancreatic duct has been suggested as a major factor in the mechanism of pain in chronic pancreatitis. Many studies investigating pain relief after endoscopic treatment of pancreatic duct (PD) are available, but the number of studies regarding the morphological changes to pancreas such as changes in PD caliber, pancreatic parenchyma, and especially pancreatic volume is far fewer.

Inhibitory Activity of Silver Nanoparticles Synthesized Using against Biofilm Formation in Species.

This paper investigated the antifungal and antibiofilm activity of silver nanoparticles synthesized with extracts against species. extracts obtained by homogenization were mixed with silver nitrate to synthesize silver nanoparticles. Analysis of the particle characteristics by UV-Vis spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX), dynamic light scattering (DLS), and Fourier transform infrared spectroscopy (FT-IR) confirmed that the extracts effectively served as reductants and capping agents.

An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users.

Human and animal studies have shown that heavy cannabis (CB) use interacts with glutamatergic signaling. Additionally, recent studies have suggested that glutamate (Glu) may drive resting state functional connectivity (RSfc). The aims of the current preliminary study were to: 1) determine whether dorsal anterior cingulate cortex (dACC) Glu is related to RSfc between the dACC and two nodes of the reward network, the nucleus accumbens (NAc) and hippocampus (Hp); and 2) determine whether CB use interacts with the relationship between dACC Glu and RSfc.

Prenatal Maternal Stress, Child Cortical Thickness, and Adolescent Depressive Symptoms.

Prenatal maternal stress predicts subsequent elevations in youth depressive symptoms, but the neural processes associated with these links are unclear. This study evaluated whether prenatal maternal stress is associated with child brain development, and adolescent depressive symptoms using a prospective design with 74 mother child pairs (40 boys). Maternal stress was assessed during pregnancy, child cortical thickness at age 7, and depressive symptoms at age 12.