Inhibitory Activity of Silver Nanoparticles Synthesized Using against Biofilm Formation in Species.

Nanomaterials (Basel)

Department of Health and Safety Convergence Science, Graduate School, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.

Published: October 2019


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Article Abstract

This paper investigated the antifungal and antibiofilm activity of silver nanoparticles synthesized with extracts against species. extracts obtained by homogenization were mixed with silver nitrate to synthesize silver nanoparticles. Analysis of the particle characteristics by UV-Vis spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX), dynamic light scattering (DLS), and Fourier transform infrared spectroscopy (FT-IR) confirmed that the extracts effectively served as reductants and capping agents. Minimum inhibitory concentration (MIC) tests were conducted to confirm antifungal activity against species. In all the tested species, the silver nanoparticles inhibited the growth of . Moreover, the SEM images of species treated with silver nanoparticles synthesized using natural extracts of showed that silver nanoparticles adhered to the surface of which induced pore formation in the membranes and prevented their normal growth. Ultimately, these abnormal forms of were thought to be less able to form biofilms than normal . The antifungal and antibiofilm activities of silver nanoparticles against are expected to be utilized in various fields and contribute in particular to developments in nanomedicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915333PMC
http://dx.doi.org/10.3390/nano9111512DOI Listing

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