Results of a national survey among occupational physicians to estimate the number of workers with active medical devices and their types in the context of managing electromagnetic hazards.

Introduction: Occupational exposure to electromagnetic fields (EMF) is almost ubiquitous: workers with Active Implantable Medical Devices (AIMD) and Active Wearable Medical Devices (AWMD) are considered at particular risk with respect to occupational risk assessment and health surveillance (HS) procedures, due to possible electromagnetic hazards resulting in interference problems. The identification of these workers is therefore fundamental for prevention purposes. Aim of the study is to provide an estimate of the proportion of workers with AIMD and AWMD, and to list the main types of devices involved.

Dermoscopic Image Digital Post-Processing Perception and Use Among Members of the International Dermoscopy Society: Results of a Web-based Survey.

Introduction: Speculatively, digital image post-processing (DIPP) enhances diagnostic accuracy in dermoscopy.

Objective: We aimed to investigate the advantages and limitations of DIPP, as well as its perceived reliability and safety.

Methods: In this study we investigated the perception and use of DIPP among members of the International Dermoscopy Society through a web-based survey with 17 questions focusing on: (i) demographics (sex, age, nationality, specialty, professional experience in dermoscopy), (ii) application of digital dermoscopy, (iii) imaging devices, (iv) DIPP software usage, (v) area of DIPP application (e.

Diagnostic Accuracy of Magnified Dermoscopy and Reflectance Confocal Microscopy in Assessing Melanocytic Lesions.

Introduction: Magnified dermoscopy (MD), or optical super-high magnification dermoscopy, is an emerging technique in dermatology.

Objectives: The study aimed to evaluate the distribution of conventional dermoscopy, MD, and reflectance confocal microscopy (RCM) features in dermoscopically equivocal pigmented lesions and to estimate their diagnostic accuracy.

Methods: A retrospective analysis of conventional dermoscopic (20x), MD (400x), and RCM images of dermoscopically equivocal pigmented lesions, diagnosed as either nevi or melanoma, was performed.

Real-World Efficacy of Tirbanibulin in Actinic Keratosis Treatment: Expert Consensus and Clinical Insights.

Introduction: Tirbanibulin, a topical treatment for actinic keratosis (AK) with a novel antiproliferative mechanism of action, has demonstrated efficacy and a favorable tolerability profile in clinical trials and real-life studies. An insight into best-practice use of tirbanibulin in different clinical presentations of AK would be useful.

Objectives: The aim of this article was to deliver advice, via expert consensus, on the optimal use of tirbanibulin in the real-life management of AK.

Plant-based diets and risk of type 2 diabetes: systematic review and dose-response meta-analysis.

Type 2 diabetes (T2D) incidence has been steadily increasing over the past few decades. Several studies have evaluated the effect of plant-based, vegetarian or vegan diets on the risk of T2D, although their potential benefits need to be confirmed and characterised. We performed a literature search up to 10 July 2025, using the terms/keywords related to plant-based index (PDI), vegetarian/vegan diets and T2D.

Long-term outcomes in deceased versus living donor liver transplantation for hepatocellular carcinoma: a bi-institutional study of 486 cases.

Background: Liver transplantation (LT) is a curative treatment for hepatocellular carcinoma (HCC), but access is often limited by organ shortage and prolonged waiting times. Living donor liver transplantation (LDLT) offers timely transplantation and may improve oncologic outcomes compared to deceased donor liver transplantation (DDLT).

Methods: This retrospective cohort study included 486 patients with HCC who underwent LT at two high-volume centers between 2010 and 2020.

Evidence of airborne dispersion of respirable-sized carcinogenic erionite fibres of volcanic origin.

Erionite is a naturally occurring fibrous zeolite classified as a Group 1 carcinogen. Although the aerosolization and characteristics of erionite fibres found within sedimentary rock formations have been extensively studied, the potential forerionite fibres, particularly the woolly type found in vugs and vesicles within volcanic rocks to become airborne, and their resulting characteristics remains poorly understood. This study investigates the occurrence and characteristics of volcanic woolly erionite fibres in surface dust collected from shrub twigs near an erionite-bearing outcrop in Gawler Downs, New Zealand.

Seizures and breathing: lessons from peri-ictal respiratory disturbances.

Breathing can be disrupted by pathological neurological conditions, such as seizures. Ictal respiratory changes comprise central or obstructive apnea, tachypnea, bradypnea, hypoventilation, and hypoxemia. Ictal central apnea (ICA) has been described in association with focal seizures, especially of temporal origin, occurring in 36%-40% of ictal events.

American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel.

Objective: Vacuoles E1 enzyme X-linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.

Methods: Given the variability in disease presentation and the limited number of studies to date, no clinical documents currently exist to provide guidance to health care providers about the management of VEXAS.

Robotic spine surgery compared with fluoroscopic-assisted surgery: advantages, disadvantages, future perspectives.

Background: Robotic spine surgery (RSS) could potentially overcome some limitations of fluoroscopic-assisted surgery (FAS). The aim of this study was to analyze RSS advantages compared to FAS and the impact of a dedicated nursing team on surgical workflow efficiency.

Materials And Methods: We retrospectively analyzed 260 adult patients with thoracolumbar degenerative/traumatic instability.

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments.

Members of the gasdermin (GSDM) family are pore-forming proteins primarily known for executing inflammatory cell death known as pyroptosis. GSDM-mediated pore formation at the plasma membrane (PM) facilitates the selective secretion of immunomodulatory proteins and nonselective ionic fluxes during pyroptotic signaling. Recent findings suggest that GSDMs also modulate intracellular processes by associating with and altering membranes in various organelles, including mitochondria, lysosomes, endoplasmic reticulum (ER), and the nucleus.

Clozapine-induced cardiac toxicity and successful rechallenge in children and adolescents: a systematic review and new case report.

Treatment-resistant schizophrenia and bipolar disorder represent first-line indications for clozapine prescription in children and adolescents, who display treatment-resistance significantly more often than adults. However, titrating clozapine up to reach an effective dose may become impossible if serious adverse events occur, forcing drug discontinuation. Here we systematically review all articles available in PubMed regarding clozapine-associated cardiac toxicity in children and adolescents, primarily including myocarditis and pericarditis, and focus on the feasibility of clozapine rechallenge after drug discontinuation.

Multidrug-resistant bacterial colonization affects postoperative outcomes after pancreaticoduodenectomy.

Background: Bile colonization after biliary drainage is associated with a greater rate of morbidity and mortality after pancreaticoduodenectomy. The increased use of antibiotics has led to a greater rate of bile colonization by multidrug-resistant microorganisms. This study aimed to analyze the correlation between multidrug-resistant microorganisms and the rate of postoperative complications.

Idiopathic scrotal hematoma in newborns: a case report and literature review.

Neonatal acute scrotum is an uncommon condition, with testicular torsion being the most critical differential diagnosis. Idiopathic scrotal hematoma is a rare entity characterized by scrotal swelling and discoloration, with preserved testicular perfusion. Differentiating idiopathic scrotal hematoma from testicular torsion is challenging but essential to avoid unnecessary surgery.

Contemporary rates and predictors of prolonged hospital stay after radical cystectomy: a population-based analysis.

Objective: To test contemporary rates and predictors of prolonged hospital stay after radical cystectomy (RC) and ileal conduit in non-metastatic bladder cancer patients.

Methods: Within the National Inpatient Sample database (NIS, 2008-2019), we identified ileal conduit RC patients and tabulated length of stay (LOS) ≥ 75th percentile vs. others.

Liver Transplantation Versus Alpps for Colorectal Liver Metastases: An Entropy Balanced Retrospective Analysis.

Objective: The primary endpoint of this study was to compare liver transplantation (LT) with Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) in the treatment of colorectal liver metastases (CRLM).

Summary Background Data: ALPPS is usually performed for borderline CRLM cases and published oncological outcomes appear to be inferior to those obtained after LT.

Methods: All consecutive patients undergoing ALPPS for CRLM across 14 centers between September 2012 and September 2022 were considered.

Advanced architectures of electrochemical interfaces.

is delighted to introduce a Collection of articles on the intricate subject of electrochemical interfaces. Here, the Guest Editors introduce the topic, outline some of the themes covered by the Collection content, and look to the future of the field.

Establishing shared definitions of virological failure and discontinuation for long-acting injectable cabotegravir and rilpivirine therapy (the CONSENSUS-LAI Study): an international survey and Delphi process.

Background: Definitions of virological failure and treatment discontinuation for long-acting injectable (LAI) cabotegravir and rilpivirine antiretroviral therapy are inconsistent in clinical practice and observational studies, which complicates interpretation and implementation of findings. The CONSENSUS-LAI study aimed to establish consistent definitions of virological failure and treatment discontinuation to enhance evidence transferability and support optimal clinical outcomes.

Methods: The study had two phases.

A multilab investigation into the N2pc as an indicator of attentional selectivity: Direct replication of Eimer (1996).

The N2pc is widely employed as an electrophysiological marker of an attention allocation. This interpretation was largely driven by the observation of an N2pc elicited by an isolated relevant target object, which was reported as Experiment 2 in Eimer (1996). All subsequent refined interpretations of the N2pc had to take this crucial finding into account.

Encoding of visual stimuli and behavioral goals in distinct anatomical areas of monkey ventrolateral prefrontal cortex.

The lateral prefrontal cortex has been classically defined as an associative region involved in the so-called executive functions, such as guiding behavior based on abstract rules and mnemonic information. However, most neurophysiological studies on monkeys did not address the issue of whether distinct anatomical sectors of lateral prefrontal cortex play different functional roles. The main aim of this work is to study functional properties of neurons recorded from a large part of ventrolateral prefrontal cortex (VLPF) of two monkeys performing passive visual tasks and a visuo-motor task, and to map them on the anatomical areas defined on the basis of our recent parcellations.

Life Expectancy of Transplanted Livers - HOPE Against Aging?

Objective: To investigate the impact of cumulative liver age on graft survival in liver transplant recipients.

Summary Of Background Data: Organ shortage has led to increased use of elderly donor livers for an ageing group of recipients, particularly in Europe. We hypothesized that hypothermic oxygenated perfusion (HOPE) enhances graft resilience against aging in livers from elderly donors.

Real world effectiveness of anti-CGRP monoclonal antibodies over three consecutive one-year treatment cycles: An intention-to-treat analysis.

BackgroundThe present prospective, real-world study aims to assess anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) effectiveness across three consecutive one-year treatment cycles by means of a conservative intention-to-treat (ITT) analysis.MethodsWe enrolled 179 subjects (75.4% females, 51.

The Use of Coping Strategies for Everyday Challenges by University Students: Brazil-Finland Cross-National Study.

The coping pattern of individuals who experience different cultures is influenced by different worldviews and ways of dealing with problems. This study aimed to estimate the psychometric properties of the BriefCOPE inventory and to compare coping strategies between Brazilian and Finnish university students. The study also aimed to identify how individual characteristics relate to coping strategies and explore the interconnections among strategies within the student samples from both countries.