Development of Beta vulgaris L. extract-finished plasma-cured recycled linen fabrics as a chromogenic sensor for sweat sensing.

A novel smart textile swab was developed as an analytical tool for the onsite evaluation of biochemical changes in sweat toward potential applications in healthcare monitoring and drug testing. Betalain (BTA) was extracted from beetroot (Beta vulgaris L.) using a simple procedure.

Novel guanidine derivatives as mechanistic scaffolds for anticancer agents: synthesis, characterization, DNA-binding, and computational studies.

Cancer continues to be a major global health challenge, necessitating the ongoing development of novel small-molecule therapeutics that can selectively target DNA and disrupt cancer cell proliferation. In this study we report the synthesis and characterization of novel guanidine derivatives (7a-j). Their DNA-binding potential was assessed through electronic absorption spectroscopy, revealing characteristic hypochromic shifts indicative of minor groove-binding interactions with salmon sperm DNA (SS-DNA).

Diagnosis of misalignment faults using the DTCWT-RCMFDE and LSSVM algorithms.

Misalignment is among the most frequent mechanical faults in rotating electrical machines, often resulting in partial or complete motor failure over time. To tackle this issue, the present study proposes an innovative methodology for diagnosing misalignment faults in rotating electrical machines. The method integrates the dual-tree complex wavelet transform with a refined composite multiscale fluctuation dispersion entropy algorithm (DTCWT-RCMFDE) for feature extraction, combined with the least-squares support vector machines algorithm (LSSVM) for fault classification.

Synthesis, photolumescence properties, solvent effect in molecular structure level, topology, and docking studies on Sulfa drug derivative.

This study examines the analysis of infrared, Raman, electronic spectral analysis, and H, C NMR spectra. Additionally, it investigates the features of NBO properties. A study was done to investigate the electronic transition and FMOs in the gas and different solvent phases like ethanol, DMSO, and HO.

Harnessing attention-driven hybrid deep learning with combined feature representation for precise sign language recognition to aid deaf and speech-impaired people.

Speech is the primary form of communication; still, there are people whose hearing or speaking skills are disabled. Communication offers an essential hurdle for people with such an impairment. Sign Languages (SLs) are the natural languages of the Deaf and their primary means of communication.

Biological evaluation and molecular docking studies of novel aza-acyclic nucleosides as putative antimicrobial, anticancer, and antioxidant agents.

This study aimed to synthesize new aza-acyclic nucleosides (aza-acyclovir) and evaluate the efficacy of these synthetic compounds as potential antimicrobial, anticancer, and antioxidant agents. We prepared two novel aza-acyclic nucleosides via two reactions. The first reaction involved trichloroisocyanuric acid and dibenzosulphonyl diethylamine, and the second reaction involved trichloroisocyanuric acid and diethanolamine.

Integrated GIS-AHP based assessment of earthquake vulnerability and risk for urban residential buildings in Muscat, Sultanate of Oman.

This study presents a cutting-edge framework for assessing earthquake vulnerability and risk in residential areas of Al-Seeb, Muscat Governorate (Sultanate of Oman). Drawing upon a rich dataset encompassing seismic, geotechnical, structural, environmental, and socioeconomic parameters, thematic vulnerability maps were developed using a GIS-based analytic hierarchy process (GIS-AHP). These were systematically integrated to produce comprehensive risk matrices.

Calcium modified mesoporous silica from marble for the removal of cadmium, lead, chromium, iron, and manganese from Siwa Oasis groundwater.

This study assessed the health risks of heavy metal contamination in groundwater in Siwa Oasis, Egypt's northwestern desert, and their potential decontamination using a marble-based nanoporous Ca-MCM-41 structure as an adsorbent. Fe, Cd, Cr, Pb, and Mn contents exceeded World Health Organization (WHO) guidelines with potential non-carcinogenic risks and carcinogenic risks based on the hazard index (HI) and Monte Carlo simulations. Ca-MCM-41 showed significant performances in the removal of most of these toxic ions with batch saturation uptake capacities of 239 mg/g Cd(II), 252 mg/g Fe(II), 308 mg/g Pb(II), 132 mg/g Cr(VI), and 154.

Viscous and thermal effects on wave propagation in a micropolar viscothermoelastic medium with impedance considerations.

Wave propagation, a key area in seismology, plays a crucial role in fields such as mineral exploration, hydrocarbon detection, and infrastructure development. Therefore, this study investigates the propagation of plane waves in a homogeneous, isotropic, generalized micropolar viscothermoelastic medium under the influence of viscosity, the hyperbolic two-temperature (HTT) parameter, and impedance boundary conditions. By deriving and reducing the governing equations to two dimensions and transforming them using dimensionless quantities and potential functions, the present model captures the combined effects of thermal, viscous, and micropolar interactions.

An algorithm for nonlinear problems with variational inequality methods.

The purpose of this paper is to introduce a mapping in the framework of a 2-uniformly smooth and uniformly convex Banach space and obtain a common solution for the fixed point set of finite families of [Formula: see text]-enriched non-expansive mappings and ([Formula: see text],[Formula: see text])-enriched strictly pseudocontractive mappings. Two solution sets of variational inequality problems are also given. Moreover, we prove several strong convergence theorems for the fixed point set of the finite family of ([Formula: see text],[Formula: see text])-enriched strictly pseudocontractive mappings and the solution set of variational inequality problems.

Neurobehavioral Protection by Prebiotic Formulations in a Scopolamine-Induced Cognitive Impaired Zebrafish Model.

The present work evaluates the influence of two prebiotic formulations-P1 (ColonX) and P4 (a product containing AnXietate extract), at concentrations of 3 and 6 mg/L-on scopolamine (SCOP, 100 μM)-induced cognitive dysfunction and anxiety-related behaviors in adult zebrafish (Danio rerio). To assess behavioral alterations, wild-type fish were subjected to the novel tank assay (NTT), Y-maze study, and novel object recognition test protocol (NOR). The formulations were examined for potential anti-inflammatory activity and cytotoxicity.

Adsorption of Bisphenol-A by banana biochar: kinetic, isotherms and thermodynamics.

The continuous release of chemical substances like endocrine disruptor bisphenol-A (BPA) can cause harmful health and environmental effects in humans, wildlife and aquatic organisms. This study demonstrates the use of raw and biochar (treated) banana peel adsorbents for the elimination of bisphenol-A in a batch process. The sorption data revealed that optimum adsorption was attained at a pH of 8.

Mechanisms and Genetic Drivers of Resistance of Insect Pests to Insecticides and Approaches to Its Control.

The escalating challenge of resistance to insecticides among agricultural and public health pests poses a significant threat to global food security and vector-borne disease control. This review synthesizes current understanding of the molecular mechanisms underpinning resistance, including well-characterized pathways such as target-site mutations affecting nicotinic acetylcholine receptors (nAChRs), acetylcholinesterase (AChE), voltage-gated sodium channels (VGSCs), and γ-aminobutyric acid (GABA) receptors, and metabolic detoxification mediated by cytochrome P450 monooxygenases (CYPs), esterases, and glutathione S-transferases (GSTs). Emerging resistance mechanisms are also explored, including protein sequestration by odorant-binding proteins and post-transcriptional regulation via non-coding RNAs, such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs).

Insights on Regioselective Synthesis of Fused Thiazoles: Density Functional Theory Calculations, Local Reactivity Indices, and Molecular Electrostatic Potential Analysis.

A regioselective protocol is developed and validated for the synthesis of pyrazolo[3,4-d]thiazoles and polycyclic-fused thiazoles through the reactions of 2-[((E)-benzylidene)hydrazono]-5-[(Z)-4-methoxybenzylidene]thiazolidin-4-one with hydrazine derivatives or heterocyclic amines, respectively. The products are confirmed by spectral and elemental analyses. Density functional theory studies, including frontier molecular orbital analysis, local reactivity indices, and molecular electrostatic potential mapping, explain the observed regioselectivity and support a proposed reaction mechanism.

Rapid Dereplication of Bioactive Compounds in Plant and Food Extracts Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry.

High-throughput screening and identification of common phytochemicals are crucial for lead optimization, drug development and investigation of metabolic pathways in complex herbal extracts. The available databases contain a huge number of compounds, making it challenging and time-consuming to dereplicate valuable compounds. Therefore, the current study aimed to develop an in-house mass spectral library for the rapid dereplication of 31 commonly occurring natural products from different classes using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS).

Blending coffee white tea with flower flavor rooibos to mask the burnt flavor.

Consumer preferences for rich flavor drive rapid growth in the new-style tea beverage market ($4.74 billion by 2030). Coffee-tea, a newly emerging product that integrates both coffee and tea flavor by blending process.

Effects of Gabapentin, Valsartan, and Codeine on hemato-biochemical and histological biomarkers of male catfish (Clarias gariepinus).

Pharmaceutical residues in aquatic environments are emerging contaminants of concern due to their potential sublethal and chronic impacts on aquatic organisms. This study aimed to evaluate the subacute toxicological effects of three widely used pharmaceuticals-gabapentin (GAB), valsartan (VAL), and codeine (COD)-on male African catfish (Clarias gariepinus). Fish were randomly assigned to four groups: a control group and three treatment groups exposed for 15 days to environmentally relevant concentrations of GAB (79.

Utilization of valorised wood bark waste as an adsorbent for the uptake of Pb(II) ions.

This study investigates the potential of valorized wood bark waste as an efficient, low-cost adsorbent for removing Pb(II) ions from aqueous solutions. Valorization via pyrolysis significantly enhanced the surface area (from 105.3 to 344.

Thermoeconomic optimization of a hybrid power and cooling facility using waste heat recovery from a marine diesel engine.

Improving energy efficiency and reducing environmental impacts have become essential goals in today's world. Finding ways to utilize waste heat for generating both power and cooling is a meaningful step toward more sustainable energy use and better resource management. In this research, the aim is to enhance the basic efficiency of diesel engines by harnessing the waste heat.

Synthesis, Absorption and Emission Behaviour, Solvation, AIM, Topology, and Docking Studies on 4-(((perfluorophenyl) methylene)amino)-N-(thiazol-2-yl) Benzene Sulfonamide.

This work aims to synthesize 4-(((perfluorophenyl) methylene)amino)-N-(thiazol-2-yl) benzene sulfonamide (PFTH) and characterize it using various instrumental techniques such as UV-visible (UV-vis), fluorescence, Fourier-transform-infrared (FTIR), Raman, and nuclear magnetic resonance (NMR) spectroscopy analyses, respectively. The density functional theory (DFT) calculations have been performed using correlation-consistent polarized valence double-zeta (cc-pVDZ) basis sets and Becke, 3-parameter Lee-Yang-Parr (B3LYP) functionals, respectively. In this study, we used Gauge-Including Atomic Orbitals (GIAO) to determine the computational techniques for nuclear magnetic resonance (C NMR and H NMR) spectroscopy.

Unsupervised fake news detection on social media using hybrid Gaussian Mixture Model.

The rise of social media has revolutionized information dissemination, creating new opportunities but also significant challenges. One such challenge is the proliferation of fake news, which undermines the credibility of journalism and contributes to societal unrest. Manually identifying fake news is impractical due to the vast volume of content, prompting the development of automated systems for fake news detection.

IoT-MT: Connected Care System For Elderly Anxiety Management Via Music Therapy.

The elderly are at a higher risk of developing depression, anxiety, and other mental illnesses due to their age, chronic diseases, financial dependencies and other factors. Access to mental health services is often limited due to high cost, a low number of psychologists/therapists, and social taboos. In this paper, we propose automating the emerging technique of 'music therapy' (MT) using the internet of things (IoT) to develop a novel solution 'IoT-MT'.

Wheat Soil-Borne Mosaic Virus Disease Detection: A Perspective of Agricultural Decision-Making via Spectral Clustering and Multi-Indicator Feedback.

The rapid advancement of artificial intelligence is transforming agriculture by enabling data-driven plant disease monitoring and decision support. Soil-borne mosaic wheat virus (SBWMV) is a soil-transmitted virus disease that poses a serious threat to wheat production across multiple ecological zones. Due to the regional variability in environmental conditions and symptom expressions, accurately evaluating the severity of wheat soil-borne mosaic (WSBM) infections remains a persistent challenge.

Unexpected Family of Heterometallic Rings {CrM} with 3,5-Bis(trifluoromethyl)benzoate.

Three heterometallic rings, [PrNH][(PrNH)CrMF(BTFB)] (M is Ni, Co, or Zn, BTFBH = 3,5-bis(trifluoromethyl)benzoic acid) are reported, templated about a di--propylammonium cation. The ring contains six Cr(III) ions and two M(II) ions at the corners of an octagon, with the divalent metal ions disordered around the ring. Each edge of the octagon is bridged by a fluoride and two bridging BTFB ligands.