Publications by authors named "Rasha Jame"

A novel smart textile swab was developed as an analytical tool for the onsite evaluation of biochemical changes in sweat toward potential applications in healthcare monitoring and drug testing. Betalain (BTA) was extracted from beetroot (Beta vulgaris L.) using a simple procedure.

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Developing disposable antibacterial facemasks is crucial for preventing respiratory infections while reducing environmental waste from disposable masks. This study presents a cost-effective facemask functionalized with a nanoemulsion of bitter apple seed extract (BASE) to enhance its antimicrobial properties. BASE was extracted using microwave-assisted extraction and formulated into a nanoemulsion with an average particle size of 391.

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Wound healing is a complex process influenced by factors such as oxidative stress, microbial infections, and impaired tissue regeneration. Conventional dressings offer basic wound coverage but often lack therapeutic efficacy, particularly antimicrobial and antioxidant properties essential for optimal healing. In this study, a multifunctional wound dressing by treating the cotton fabric with bitter apple fruit extract (BAFE)-loaded solid lipid nanoparticles (SLN).

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Water pollution is a critical environmental issue that necessitates innovative approaches to water purification. This study presents the development of a novel cellulose-based adsorbent, DCNF/PEI, synthesized by grafting branched polyethyleneimine (PEI) onto dialdehyde cellulose nanofibers (DCNF) via a Schiff base reaction. This functionalization enhances the adsorption capacity of cellulose nanofibers for removing anionic dyes from aqueous solutions.

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The increasing contamination of water bodies with toxic dyes, particularly methyl orange (MO), has become a significant environmental challenge. In this study, we present an adsorbent, zinc ferrite-loaded hydroxyethyl cellulose/chitosan film (ZnFe₂O₄@HEC/Cs), designed for the efficient removal of MO dye from aqueous solutions. These composites combine the magnetic properties of ZnFe₂O₄ with the biocompatibility of HEC and Cs, forming a robust material with excellent MO dye adsorption capabilities.

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Article Synopsis
  • - This study analyzes plastic waste sources and characteristics in different Egyptian environments, including marine (Mediterranean and Red Seas), freshwater (River Nile), and urban areas.
  • - Key plastics found are polyethylene and polypropylene in marine areas, polystyrene in the River Nile, and a mix in urban settings, with varying sizes and thicknesses influenced by environmental factors.
  • - Degradation rates differ significantly based on location, highlighting the need for specific policies to combat plastic pollution in Egypt, which is important for global conservation efforts.
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The growing demand for electronic devices has led to excessive stress on Earth's resources, necessitating effective waste management and the search for renewable materials with minimal environmental impact. Bioelectronics, designed to interface with the human body, have traditionally been made from inorganic materials, such as metals, which, while having suitable electrical conductivity, differ significantly in chemical and mechanical properties from biological tissues. This can cause issues such as unreliable signal collection and inflammatory responses.

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This study focuses on the synthesis of zinc and copper oxide nanoparticles using green methods by plant extracts. The resulting metal oxides were analyzed using FT-IR spectroscopy, TGA, TEM, zeta potential and assessed for their efficacy as pigments based on properties such as Hydrogen Ion Concentration, Oil absorption, Moisture Content, Fineness of grinding, Bleeding, and loss on ignition. The results confirmed that the prepared ZnO and CuO nanoparticles exhibited the formation of nanoparticles in the range of 10-40 nm with potential as pigments.

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Background: The coumarin nuclei, which exist in many heterocyclic compounds, has gained a lot of attention over the past decade due to their wide range of biological activities such as antibacterial, anticoagulant, antiviral, antifungal, anticancer, and anti-inflammatory properties.

Objective: The multi-component reactions of 5,5-dimethylcyclohexane-1,3-dione with acetophenone derivatives and triethoxymethane produced biologically active target chromene molecules and their fused derivatives.

Methods: The reaction of 5,5-dimethylcyclohexane-1,3-dione and each of triethoxymethane and acetophenone derivatives 3a-g in absolute ethanol containing triethylamine gave the 4,6,7,8-tetrahydro-5H-chromen-5-one derivatives 4a-g.

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In this article, novel thiazol-indolin-2-one derivatives 4a-f have been synthesized via treatment of thiosemicarbazide (1) with some isatin derivative 2a-f and N-(4-(2-bromoacetyl)phenyl)-4-tolyl-sulfonamide (3) under reflux in ethanol in the presence of triethyl amine (TEA). The structures of new products were elucidated by elemental and spectral analyses. Moreover, all compounds were investigated for their in vivo anti-inflammatory activity using celecoxib as a reference drug.

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Microbial enzymes are crucial catalysts in various industries due to their versatility and efficiency. The microbial enzymes market has recently expanded due to increased demand for many reasons. Among them are eco-friendly solutions, developing novel microbial strains with enhanced enzymes that perform under harsh conditions, providing sustainability, and raising awareness about the benefits of enzyme-based products.

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In this paper, novel pyridines - were designed and synthesized via the one-pot, four-component reaction of 2-formylphenyl 4-tolylsulfonate with malononitrile, ammonium acetate, and phenols or 2-thioxo-1,3-thiazolidin-4-one or 6-aminopyrimidine-2,4(1,3)-dione under microwave irradiation in an aqueous solution of water and ethanol (1:1 ratio). The structures of new pyridines - were elucidated by elemental and spectral analyses such as IR, H NMR, and CNMR. This application has many advantages, such as having easy workup, eco-friendliness, reaction time being short (6-13 min), high production (94-98%), inexpensiveness, and avoiding the use of harmful solvents.

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Therapeutic proteins have been employed for centuries and reached approximately 50 % of all drugs investigated. By 2023, they represented one of the top 10 largest-selling pharma products ($387.03 billion) and are anticipated to reach around $653.

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The reaction of 4-(chloroacetamido)pyrimidine (1) with ammonium thiocyanate gave 2-(pyrimidin-4-ylimino)thiazolidin-4-one (2), which, when condensed with four substituted benzaldehyde analogues, gave the consequent 5-arylidine-2-(pyrimidin-4-ylimino)thiazolidin-4-ones 3a-d. In addition, the absorbance and fluorescence behaviours of pyrimidinylimino-thiazolidin-4-one hybrids 3a-d in various organic solvents were investigated. The emphasis was on studying UV absorption capacities and the effect of various structural components on photophysical qualities such as the 5-arylidene-2-(pyrimidin-4-ylimino)thiazolidin-4-ones and N,N-dimethylamino tail.

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Preparation, characterization, and investigation of a novel organic charge transfer (CT) complex were carried out, with a focus on exploring its antibacterial and antifungal characteristics. Theoretical analysis backs up the experimental findings. CT complex formed was synthesized between 8-hydroxyquinoline (8HQ) and oxalic acid (OA) at RT (room temperature).

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In this study, a polar extract of Aconitum lycoctonum L. was used for the synthesis of silver nanoparticles (AgNPs), followed by their characterization using different techniques and evaluation of their potential as antioxidants, amylase inhibitors, anti-inflammatory and antibacterial agents. The formation of AgNPs was detected by a color change, from transparent to dark brown, within 15 min and a surface resonance peak at 460 nm in the UV-visible spectrum.

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