Developing disposable antibacterial facemasks is crucial for preventing respiratory infections while reducing environmental waste from disposable masks. This study presents a cost-effective facemask functionalized with a nanoemulsion of bitter apple seed extract (BASE) to enhance its antimicrobial properties. BASE was extracted using microwave-assisted extraction and formulated into a nanoemulsion with an average particle size of 391.
View Article and Find Full Text PDFInt J Biol Macromol
August 2025
Wound healing is a complex process influenced by factors such as oxidative stress, microbial infections, and impaired tissue regeneration. Conventional dressings offer basic wound coverage but often lack therapeutic efficacy, particularly antimicrobial and antioxidant properties essential for optimal healing. In this study, a multifunctional wound dressing by treating the cotton fabric with bitter apple fruit extract (BAFE)-loaded solid lipid nanoparticles (SLN).
View Article and Find Full Text PDFWater pollution is a critical environmental issue that necessitates innovative approaches to water purification. This study presents the development of a novel cellulose-based adsorbent, DCNF/PEI, synthesized by grafting branched polyethyleneimine (PEI) onto dialdehyde cellulose nanofibers (DCNF) via a Schiff base reaction. This functionalization enhances the adsorption capacity of cellulose nanofibers for removing anionic dyes from aqueous solutions.
View Article and Find Full Text PDFThe increasing contamination of water bodies with toxic dyes, particularly methyl orange (MO), has become a significant environmental challenge. In this study, we present an adsorbent, zinc ferrite-loaded hydroxyethyl cellulose/chitosan film (ZnFe₂O₄@HEC/Cs), designed for the efficient removal of MO dye from aqueous solutions. These composites combine the magnetic properties of ZnFe₂O₄ with the biocompatibility of HEC and Cs, forming a robust material with excellent MO dye adsorption capabilities.
View Article and Find Full Text PDFThe growing demand for electronic devices has led to excessive stress on Earth's resources, necessitating effective waste management and the search for renewable materials with minimal environmental impact. Bioelectronics, designed to interface with the human body, have traditionally been made from inorganic materials, such as metals, which, while having suitable electrical conductivity, differ significantly in chemical and mechanical properties from biological tissues. This can cause issues such as unreliable signal collection and inflammatory responses.
View Article and Find Full Text PDFThis study focuses on the synthesis of zinc and copper oxide nanoparticles using green methods by plant extracts. The resulting metal oxides were analyzed using FT-IR spectroscopy, TGA, TEM, zeta potential and assessed for their efficacy as pigments based on properties such as Hydrogen Ion Concentration, Oil absorption, Moisture Content, Fineness of grinding, Bleeding, and loss on ignition. The results confirmed that the prepared ZnO and CuO nanoparticles exhibited the formation of nanoparticles in the range of 10-40 nm with potential as pigments.
View Article and Find Full Text PDFBackground: The coumarin nuclei, which exist in many heterocyclic compounds, has gained a lot of attention over the past decade due to their wide range of biological activities such as antibacterial, anticoagulant, antiviral, antifungal, anticancer, and anti-inflammatory properties.
Objective: The multi-component reactions of 5,5-dimethylcyclohexane-1,3-dione with acetophenone derivatives and triethoxymethane produced biologically active target chromene molecules and their fused derivatives.
Methods: The reaction of 5,5-dimethylcyclohexane-1,3-dione and each of triethoxymethane and acetophenone derivatives 3a-g in absolute ethanol containing triethylamine gave the 4,6,7,8-tetrahydro-5H-chromen-5-one derivatives 4a-g.
In this article, novel thiazol-indolin-2-one derivatives 4a-f have been synthesized via treatment of thiosemicarbazide (1) with some isatin derivative 2a-f and N-(4-(2-bromoacetyl)phenyl)-4-tolyl-sulfonamide (3) under reflux in ethanol in the presence of triethyl amine (TEA). The structures of new products were elucidated by elemental and spectral analyses. Moreover, all compounds were investigated for their in vivo anti-inflammatory activity using celecoxib as a reference drug.
View Article and Find Full Text PDFMicrobial enzymes are crucial catalysts in various industries due to their versatility and efficiency. The microbial enzymes market has recently expanded due to increased demand for many reasons. Among them are eco-friendly solutions, developing novel microbial strains with enhanced enzymes that perform under harsh conditions, providing sustainability, and raising awareness about the benefits of enzyme-based products.
View Article and Find Full Text PDFIn this paper, novel pyridines - were designed and synthesized via the one-pot, four-component reaction of 2-formylphenyl 4-tolylsulfonate with malononitrile, ammonium acetate, and phenols or 2-thioxo-1,3-thiazolidin-4-one or 6-aminopyrimidine-2,4(1,3)-dione under microwave irradiation in an aqueous solution of water and ethanol (1:1 ratio). The structures of new pyridines - were elucidated by elemental and spectral analyses such as IR, H NMR, and CNMR. This application has many advantages, such as having easy workup, eco-friendliness, reaction time being short (6-13 min), high production (94-98%), inexpensiveness, and avoiding the use of harmful solvents.
View Article and Find Full Text PDFThe demand for the functionalization of additive materials based on bacterial cellulose (BC) is currently high due to their potential applications across various sectors. The preparation of BC-based additive materials typically involves two approaches: in situ and ex situ. In situ modifications entail the incorporation of additive materials, such as soluble and dispersed substances, which are non-toxic and not essential for bacterial cell growth during the production process.
View Article and Find Full Text PDFBioorg Chem
February 2024
This scientific review documents the recent progress of C-spirooxindoles chemistry (synthesis and reaction mechanism) and their bioactivities, focusing on the promising results as well as highlighting the biological mechanism via the reported molecular docking findings of the most bioactive derivatives. C-Spirooxindoles are attractive bioactive agents and have been found in a variety of natural compounds, including alkaloids. They are widely investigated in the field of medicinal chemistry and play a key role in medication development, such as antivirals, anticancer agents, antimicrobials, etc.
View Article and Find Full Text PDFPreparation, characterization, and investigation of a novel organic charge transfer (CT) complex were carried out, with a focus on exploring its antibacterial and antifungal characteristics. Theoretical analysis backs up the experimental findings. CT complex formed was synthesized between 8-hydroxyquinoline (8HQ) and oxalic acid (OA) at RT (room temperature).
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