Computational prediction of the pathogenic variants of arachidonate 5-lipoxygenase activating protein using Molecular Dynamics simulation.

The arachidonate 5-lipoxygenase activating protein (ALOX5AP) regulates leukotrienes (LTs) synthesis. LTs are involved in inflammation which is implicated in cardiovascular diseases (CVDs) and stroke. Variations in ALOX5AP gene are associated with CVDs, stroke and others because of their possible effects on ALOX5AP stability and function.

Functionalization of cellulosic-based fabrics using nanoemulsion of bitter apple seed extract for protection against potential respiratory bacteria.

Developing disposable antibacterial facemasks is crucial for preventing respiratory infections while reducing environmental waste from disposable masks. This study presents a cost-effective facemask functionalized with a nanoemulsion of bitter apple seed extract (BASE) to enhance its antimicrobial properties. BASE was extracted using microwave-assisted extraction and formulated into a nanoemulsion with an average particle size of 391.

Correction: A nanomagnetic triazole-based Schiff-base complex of palladium(0) as an efficient heterogeneous catalyst for the Mizoroki-Heck C-C cross-coupling reaction under green conditions.

[This corrects the article DOI: 10.1039/D5NA00364D.].

Multifunctional cotton wound dressings enhanced with bitter apple fruit extract-loaded solid lipid nanoparticles for antimicrobial, antioxidant, and anticancer activities.

Wound healing is a complex process influenced by factors such as oxidative stress, microbial infections, and impaired tissue regeneration. Conventional dressings offer basic wound coverage but often lack therapeutic efficacy, particularly antimicrobial and antioxidant properties essential for optimal healing. In this study, a multifunctional wound dressing by treating the cotton fabric with bitter apple fruit extract (BAFE)-loaded solid lipid nanoparticles (SLN).

A nanomagnetic triazole-based Schiff-base complex of palladium(0) as an efficient heterogeneous catalyst for the Mizoroki-Heck C-C cross-coupling reaction under green conditions.

A novel magnetically recoverable palladium(0) catalyst, [FeO@triazole-Schiff-base-Pd(0)], was synthesized a simple three-step functionalization. Magnetite nanoparticles were first modified with a haloalkane silane linker to introduce C-Cl functionalities, followed by nucleophilic substitution with a triazole-Schiff-base ligand derived from 3-amino-1,2,4-triazole and salicylaldehyde. Finally, coordination with palladium chloride and reduction to Pd(0) afforded a stable, magnetically separable catalyst.

Cost-effective zinc ferrite-functionalized hydroxyethyl cellulose/chitosan film for efficient removal of methyl orange dye from aqueous solutions.

The increasing contamination of water bodies with toxic dyes, particularly methyl orange (MO), has become a significant environmental challenge. In this study, we present an adsorbent, zinc ferrite-loaded hydroxyethyl cellulose/chitosan film (ZnFe₂O₄@HEC/Cs), designed for the efficient removal of MO dye from aqueous solutions. These composites combine the magnetic properties of ZnFe₂O₄ with the biocompatibility of HEC and Cs, forming a robust material with excellent MO dye adsorption capabilities.

Binomial-discrete Erlang-truncated exponential mixture and its application in cancer disease.

Among diseases, cancer exhibits the fastest global spread, presenting a substantial challenge for patients, their families, and the communities they belong to. This paper is devoted to modeling such a disease as a special case. A newly proposed distribution called the binomial-discrete Erlang-truncated exponential (BDETE) is introduced.

Leverage and influential observations on the Liu type estimator in the linear regression model with the severe collinearity.

In the process of building a linear regression model, the essential part is to identify influential observations. Various influence measures involving Cook's distance and DFFITS are designed to detect the linear regression's influential observations using the Least Squares (LS). The existence of influential observations in the data is complicated by the presence of severe collinearity and affects the efficiency of the detection measures.