Decoding the expression patterns and characterisation of calmodulin and calmodulin-like gene families in watermelon () under abiotic stresses.

Calmodulin (CaM) and calmodulin-like (CML) gene families are important in combating stress conditions in plants. A total of 36 CaMs/CMLs were identified and found to be randomly dispersed over the 11 chromosomes of Citrullus lanatus (watermelon). Domain analysis verified the presence of characteristic four EF-hand domains in ClCaM proteins and 2-4 EF-hand domains in ClCML proteins.

Effective substitution of ferrous sulfate with iron oxide nanoparticles enhances growth, antioxidant activity, and stevioside accumulation in micro-propagated rebaudiana.

Nanotechnology, particularly the use of iron oxide nanoparticles (IONPs), has gained significant attention in agricultural research due to its potential to enhance plant growth, development, and stress tolerance. However, the green synthesis of IONPs using plant extracts remains underexplored, especially in the context of agricultural applications. In this study, the green synthesis of IONPs using leaf extract is reported, with the extract serving as both a reducing and capping agent.

Green Synthesis of Selenium Nanoparticles Using Equisetum diffusum: Characterization, Antibacterial Potential, Effects on Plant Growth.

This study explores the green synthesis of selenium nanoparticles (SeNPs) using Equisetum diffusum (D ED) aqueous extract and evaluates their nanofertilizer and antibacterial potential. The synthesized SeNPs were characterized by UV-Vis spectroscopy, FTIR, XRD, SEM, EDX, DLS, TGA, and DSC, confirming their stability, spherical morphology, and high purity. The UV-Vis spectrum established a peak at 371 nm, and SEM analysis revealed an average particle size of 18.

Subtractive proteomics and reverse-vaccinology approaches for novel drug targets and designing a chimeric vaccine against strain RJX1120.

, also known as , is a Gram-positive anaerobic bacterium that resides in the human gut microbiota. Notably, this bacterium plays dual roles in health and disease. On one side it supports nutrient metabolism essential for bodily functions and on the other it contributes to the development of Inflammatory Bowel Disease (IBD) and other gastrointestinal disorders.

Hybrid strengthening of cellulose nanocrystal-based solvent co-cross linked flexible organohydrogels with fast self-healing, diverse adhesive nature, and anti-freezing behavior for advanced human health monitoring.

Continuous real-time monitoring of non-cognitive markers is essential for the preliminary detection, control, and regulation of long-standing health conditions. Existing diagnostic techniques are frequently invasive and often not well suited for at-home monitoring, limiting their use in early detection of disorders. In this study, a flexible organohydrogel-based wearable sensor has been developed offering high accuracy and durability for real-time human health assessment.

Gastro retentive floating drug delivery system of levofloxacin based on Aloe vera hydrogel: In vitro and in vivo assays.

Gastro retentive drug delivery systems (GRDDS) have gained immense popularity as they reduce dosing frequency, improve bioavailability, and enhance patient compliance. Herein, a plant-based, controlled swelling, and pH-sensitive GRDDS based on Aloe vera hydrogel and cellulose was developed for the sustained release of levofloxacin (LEVO). The properties of five various floating tablet formulations including dynamic swelling, pH-responsiveness, hardness, friability, drug release, and buoyant time were evaluated.

A superporous and pH-sensitive hydrogel from (chia) seeds: stimuli responsiveness, on-off switching, and pharmaceutical applications.

The use of plant seed-based hydrogels to design drug delivery systems (DDSs) has increased due to their swellable, pH-responsive, biocompatible, biodegradable, and non-toxic nature. Herein, the chia seeds hydrogel (CSH) was extracted through an aqueous extraction method to explore its pH and salt-responsive swelling behavior and sustained release potential. The CSH was characterized using Fourier transform infrared (FT-IR) and solid-state cross-polarization magic angle spinning carbon-13 nuclear magnetic resonance (solid/state CP-MAS C/NMR) spectra.

Analysis of a class of fractal hybrid fractional differential equation with application to a biological model.

Recently, the area devoted to fractional calculus has given much attention by researchers. The reason behind such huge attention is the significant applications of the mentioned area in various disciplines. Different problems of real world processes have been investigated by using the concepts of fractional calculus and important and applicable outcomes were obtained.

Dually-crosslinked ionic conductive hydrogels reinforced through biopolymer gellan gum for flexible sensors to monitor human activities.

Human-machine interactions, monitoring of health equipment, and gentle robots all depend considerably on flexible strain sensors. However, making strain sensors have better mechanical behavior and an extensive sensing range remains an urgent difficulty. In this study, poly acrylamide-co-butyl acrylate with gellan gum (poly(AAm-co-BA)@GG) hydrophobic association networks and intermolecular hydrogen bonding interactions are used to fabricate dual cross-linked hydrogels for wearable resistive-type strain sensors.

Designing of a multi-epitopes based vaccine against and its validation through integrated computational approaches.

is a Gram-negative opportunist pathogen within the mucus of the nose and mouth without significant symptoms and has an ability to cause various infections ranging from ear, eye, and sinus to pneumonia. A concerning development is the increasing resistance of to beta-lactam antibiotics, with the potential to cause dental infections or abscesses. The principal objective of this investigation is to utilize bioinformatics and immuno-informatic methodologies in the development of a candidate multi-epitope Vaccine.

Unveiling the aesthetic secrets: exploring connections between genetic makeup, chemical, and environmental factors for enhancing/improving the color and fragrance/aroma of .

Floral color and scent profiles vary across species, geographical locations, and developmental stages. The exclusive floral color and fragrance of is contributed by a range of endogenous chemicals that distinguish it from other flowers and present amazing ornamental value. This comprehensive review explores the intricate interplay of environmental factors, chemicals and genes shaping the flower color and fragrance of .

Color-tunable stable quasi-2D hybrid metal halide perovskites: synthesis, characterization, and optical analysis.

Metal halide perovskites show remarkable optical properties and useful applications in optoelectronic devices. However, the instability of three-dimensional (3D) metal halide perovskites limits their applications, leading to the emergence of more stable two-dimensional (2D) metal halide perovskites. Herein, we present a facile synthesis of the 2D hybrid metal halide perovskite (EDA)(MA)PbBr (EDA: ethylene diammonium, MA: methylammonium), where = 1-6, and MAPbBr perovskite layers using an anti-solvent co-precipitation technique.

Diffused sunlight assisted green synthesis of silver nanoparticles using polar extract for antimicrobial and wound healing applications.

The current study reports the synthesis of silver nanoparticles (Ag NPs) using a polar extract of leaves. Various analytical techniques, like UV-Vis spectrophotometry, FT-IR spectroscopy, XRD, SEM, and EDX were employed for characterisation. These techniques confirmed the stability of Ag NPs in solution and endorsed the interaction between different groups and Ag, crystal phase, surface morphology, and size of Ag NPs.

Enhanced Electrocatalytic Activity of Amorphized LaCoO for Oxygen Evolution Reaction.

Amorphous inorganic perovskites have attracted significant attention as efficient electrocatalysts due to their unique structural flexibility and good catalytic activity. In particular, the disordered structure and a surface rich in defects such as oxygen vacancies can contribute to the superior electrocatalytic activity of amorphous oxides compared to their crystalline counterpart. In this work, we report the synthesis of LaCoO, followed by an amorphization process through urea reduction with tailored modifications.

Compost and humic acid amendments are a practicable solution to rehabilitate weak arid soil for higher winter field pea production.

Arid soils are often weak, low in fertility, and lack essential plant nutrients. Organic amendments might be a feasible solution to counter the detrimental impact and rehabilitate weak arid soil for the growth of legumes. The study aimed to investigate how organic amendments of compost and humic acid may affect winter field pea productivity in arid soil.

Aconitum lycoctonum L. (Ranunculaceae) mediated biogenic synthesis of silver nanoparticles as potential antioxidant, anti-inflammatory, antimicrobial and antidiabetic agents.

In this study, a polar extract of Aconitum lycoctonum L. was used for the synthesis of silver nanoparticles (AgNPs), followed by their characterization using different techniques and evaluation of their potential as antioxidants, amylase inhibitors, anti-inflammatory and antibacterial agents. The formation of AgNPs was detected by a color change, from transparent to dark brown, within 15 min and a surface resonance peak at 460 nm in the UV-visible spectrum.

In vitro evaluation of herbal based Lesh Nat B cream against .

Pentavalent antimonials continue to be the standard treatment for cutaneous leishmaniasis. But their use is retarded owing to highly-priced, prolonged hospitalization, noxious and poor solubility. Therefore, there is a dire need to characterize new potential compounds possessing anti-leishmanial activity.

Genetic Investigation of Consanguineous Pakistani Families Segregating Rare Spinocerebellar Disorders.

Spinocerebellar disorders are a vast group of rare neurogenetic conditions, generally characterized by overlapping clinical symptoms including progressive cerebellar ataxia, spastic paraparesis, cognitive deficiencies, skeletal/muscular and ocular abnormalities. The objective of the present study is to identify the underlying genetic causes of the rare spinocerebellar disorders in the Pakistani population. Herein, nine consanguineous families presenting different spinocerebellar phenotypes have been investigated using whole exome sequencing.

Biogenic silicon nanoparticles mitigate cadmium (Cd) toxicity in rapeseed (Brassica napus L.) by modulating the cellular oxidative stress metabolism and reducing Cd translocation.

Nano-enabled strategies have emerged as promising alternatives to resolve heavy metals (HMs) related harms in an eco-friendly manner. Here, we explored the potential of biogenic silicon nanoparticles (SiNPs) in alleviating cadmium (Cd) stress in rapeseed (Brassica napus L.) plants by modulating cellular oxidative repair mechanisms.

Improved Photocatalytic and Antioxidant Activity of Olive Fruit Extract-Mediated ZnO Nanoparticles.

Photodegradation is an efficient strategy for the removal of organic pollutants from wastewater. Due to their distinct properties and extensive applications, semiconductor nanoparticles have emerged as promising photocatalysts. In this work, olive () fruit extract-based zinc oxide nanoparticles (ZnO@OFE NPs) were successfully biosynthesized using a one-pot sustainable method.

The development of chiral metal-organic frameworks for enantioseparation of racemates.

MIL-101(Cr), an achiral metal-organic framework, made up of a terephthalic acid ligand and a metal chromium ion was selected as a template. Its structural features are unsaturated Lewis acid sites that can be easily activated and it has an extremely high specific surface area, big pore size, and good thermal/chemical/water stability. This achiral framework was modified to introduce chirality within the structure to develop chiral metal-organic frameworks (CMOFs).