Effect of Preoperative Budesonide on Postoperative Sore Throat: A Systematic Review and Meta-Analysis.

Postoperative sore throat (POST) is a common complication following endotracheal intubation. Various pharmacological interventions have been explored for POST prevention, with budesonide emerging as a promising option due to its anti-inflammatory properties. PubMed, Scopus, Web of Science and the Cochrane Library were searched following PRISMA guidelines.

Trichobezoar-induced gastric outlet obstruction in a 17-year-old girl: a case report.

Gastric outlet obstruction (GOO) is an uncommon, yet potentially severe, condition arising from multiple causes, including ingesting foreign bodies. The formation of plastic bezoars or trichobezoars due to swallowing indigestible materials remains a rare cause, especially among children exhibiting pica behavior (Vaughan The Rapunzel syndrome: an unusual complication of intestinal bezoar. 1968;:339-43).

Exploring the Association Between COVID-19 and Avascular Necrosis: A Systematic Review.

Avascular necrosis (AVN) has emerged as an extrapulmonary complication associated with COVID-19 and corticosteroids. This review aims to evaluate the association between COVID-19 infection, corticosteroid use, and the development of AVN. We conducted a systematic review following the PRISMA guidelines, searching five databases until May 30, 2024.

Therapeutic potential of heat-killed Enterococcus faecalis (EC-12) para-probiotic in reversing maternal separation-triggered social deficit in mice.

Early life stress due to maternal separation (MS) disrupts the gut-brain axis (GBA), leading to long-term neurobiological and behavioral deficits, particularly social behavior impairments. Although various probiotics have shown therapeutic potential, the efficacy of heat-killed Enterococcus faecalis EC-12 (EC-12) as a para-probiotic remains largely unknown. This study aimed to evaluate the therapeutic potential of EC-12 in reversing MS-induced behavioral and molecular abnormalities in mice.

A comprehensive systematic review of randomized controlled trials on anesthetic agents in children's upper gastrointestinal endoscopy: highlighting safety concerns and efficacy.

Upper gastrointestinal endoscopy (GIE) is essential for diagnosing and treating gastrointestinal disorders in children aged 6-12 years, yet it often requires sedation due to the significant discomfort and pain involved. We conducted a PRISMA 2020-compliant systematic review of randomized controlled trials (RCTs) from PubMed, Web of Science, Scopus, and Ovid (inception to March 30, 2024). Inclusion criteria are as follows: RCTs comparing sedative regimens (e.

Sustainable valorization of olive by-products: environmental impact, biotechnological and probiotic approaches for bioactive recovery in alignment with circular bioeconomy.

The olive oil industry generates vast amounts of by-products, including olive pomace, olive mill wastewater, olive pits, and olive leaves, which pose serious environmental and economic challenges. However, these residues are rich in bioactive compounds such as polyphenols, dietary fibers, unsaturated fatty acids, and sugar derivatives, making them valuable resources for sustainable valorization. This review explores innovative biotechnological and probiotic-driven approaches to convert olive waste into high-value products, aligning with the United Nations Sustainable Development Goals (SDGs), particularly SDG 12 (Responsible consumption and production) and SDG 13 (Climate action).

Serum golgi protein-73 (GP-73) in children with autoimmune hepatitis.

Unlabelled: To assess the correlation between serum Golgi protein-73 (GP-73) and the degree of hepatic fibrosis in children with autoimmune liver diseases. This case-control study included 100 children. Group A involved 50 children with autoimmune hepatitis (AIH), aged 2-17 years (mean 11.

Optimizing ketamine dosing strategies across diverse clinical applications: a comprehensive review.

Ketamine has emerged as a versatile therapeutic agent with applications spanning anesthesia, pain management, and psychiatric disorders. This review examines ketamine's clinical utility across diverse administration routes, including intravenous, intramuscular, intranasal, and oral, emphasizing the need to individualize dosing regimens. We explore factors influencing ketamine dosing, such as patient characteristics (age, weight, comorbidities), concomitant medications, and desired clinical effects, while balancing efficacy and side effects.

Precision diagnosis of citrus leaf diseases using image enhancement and nonlinear fuzzy ranking ensemble approach NLFuRBe.

Citrus fruits, especially lemons, play a vital economic and nutritional role worldwide but are increasingly threatened by a wide range of diseases that diminish yield quality and quantity. Traditional manual and automated methods for disease detection requires domain expert, ample observation time, and is often ineffective during early infection stages. This paper presents a novel automated approach for the symptom based detection and classification of citrus leaf diseases using a nonlinear Fuzzy Rank-Based Ensemble (NL-FuRBE) methodology, enhanced by image quality improvement techniques.

MDL-800 protects against inflammatory and metabolic dysfunction: role of SIRT6 in the cross-regulation of NFκB, AMPK, and PPAR signaling in rats.

Metabolic syndrome (MetSyn) is a complex, multifactorial disorder characterized by insulin resistance, dyslipidemia, hepatic steatosis, oxidative stress, and chronic inflammation, contributing substantially to the global burden of cardiometabolic diseases. Despite extensive research, effective pharmacological strategies that address the diverse and interconnected pathophysiological mechanisms of MetSyn are lacking. Sirtuin 6 (SIRT6), a NAD-dependent epigenetic regulator, has emerged as a critical modulator of metabolic and inflammatory homeostasis.

Concurrent high-grade appendiceal mucinous neoplasm and adenocarcinoma: a unique case report and literature review.

Appendiceal neoplasms (ANs) are rare and often mimic acute appendicitis, complicating timely diagnosis. We report a unique case of a 57-year-old male presenting with right lower quadrant pain, found on imaging to have a ruptured appendiceal mucocele. He underwent open right hemicolectomy, and histopathology revealed concurrent moderately differentiated mucinous adenocarcinoma arising within a high-grade appendiceal mucinous neoplasm-the first such case documented in the literature.

Transomental hernia causing small bowel obstruction: an uncommon surgical emergency and literature review.

Transomental hernia (TOH) is an exceedingly rare subtype of internal hernia, often leading to acute small bowel obstruction with a high risk of ischemia. We present the case of a 58-year-old male with a history of laparoscopic inguinal hernia repair who developed abdominal pain, distension, vomiting, and obstipation. Contrast-enhanced computed tomography revealed clustered dilated ileal loops with a transition point suggestive of internal herniation.

Advancing sustainable nursing leadership: the interplay of green absorptive capacity, intellectual capital, and knowledge management among nursing managers.

Background: Achieving sustainable performance in healthcare organizations has become a pressing necessity, driven by environmental challenges and the imperative for enhanced efficiency. Within nursing leadership, the integration of green absorptive capacity, green intellectual capital, and green knowledge management has emerged as a strategic approach to fostering sustainability. However, empirical research on the interplay of these green competencies in the nursing sector remains limited.

Functionalizing cottonseed protein by sequential pH-shifting and ultrasonication.

The physicochemical, functional, rheological, conformational, and thermal attributes of cottonseed meal protein (CMP) prepared by pH-shifting and/or ultrasonication were investigated. CMP isolates were altered using acidic (pH 1.5, 3.

LPS mediated neuronal c-Fos activation: whole-brain mapping, site and time effect in intoxicated mice.

Lipopolysaccharide (LPS; a bacterial endotoxin) treatment causes acute inflammatory conditions. Acute inflammation causes the brain to activate neurons in some brain nuclei known as circumventricular organs. The c-Fos immunoreaction could be used to assess this neural activity.

Correction: modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis.

[This corrects the article DOI: 10.3389/fphar.2024.

Empagliflozin reduces left ventricular mass increase and improves cardiomyocyte hypertrophy after 5/6 nephrectomy.

Left ventricular hypertrophy (LVH) is a common cardiac complication in patients with cardiorenal syndrome. Empagliflozin has demonstrated cardio-renal protective effects in clinical studies, potentially linked to reductions in left ventricular mass (LVM). Using a 5/6 nephrectomy rat model to induce cardiorenal syndrome, we administered two doses of Empagliflozin (3 mg/kg/day and 15 mg/kg/day) via gavage for 95 days, with Telmisartan as a positive control.

From Hue to Health: Exploring the Therapeutic Potential of Plant-Pigment-Enriched Extracts.

The escalating global challenges of antimicrobial resistance (AMR) and cancer necessitate innovative therapeutic solutions from natural sources. This study investigated the multifaceted therapeutic potential of pigment-enriched plant extracts. We screened diverse plant extracts for antimicrobial and antibiofilm activity against multidrug-resistant bacteria and fungi.

Effects of Two Low-Frequency Intradialytic Cycling Training Programs on Functional Capacity in Subjects Undergoing Hemodialysis: A Randomized Controlled Trial.

Introduction: Functional capacity deteriorates over time in patients on hemodialysis, which is associated with increased mortality risk. This study aimed to assess the effects of two low-frequency (i.e.

Mesenchymal stem cell therapy in veterinary orthopaedics: Evidence from canine clinical medicine.

Mesenchymal stem cell (MSC) therapy is a promising approach for treating orthopaedic conditions in veterinary clinical patients. MSCs exhibit remarkable regenerative properties, including multilineage differentiation, immunomodulation, and tissue repair, making them an attractive alternative to conventional therapies. This comprehensive review explores the clinical potential of MSCs in managing a range of canine orthopaedic disorders, including fractures, degenerative joint diseases, and tendon injuries.

Monoallelic variants in ACVR1 in a cohort of Egyptian individuals with fibrodysplasia ossificans progressiva.

Objectives: Fibrodysplasia ossificans progressiva (FOP) is a rare ectopic ossification disorder of connective tissue deposited in the muscles, fascia, tendons, and ligaments. The disease is an autosomal dominant pattern caused by pathogenic variants of ACVR1. Herein, we describe the largest number of affected individuals from the Middle East North Africa region who presented with FOP.

Beneficial Role of Zinc in Metabolic Syndrome: Understanding the Underlying Pathophysiological Mechanisms.

Metabolic syndrome (MetS) is a complex disorder that comprises metabolic abnormalities such as central obesity, insulin resistance, dyslipidemia, and hypertension. Eventually, MetS leads to type 2 diabetes (T2DM) and increases the risk of other cardiovascular diseases. Patients with MetS are approximately five times more prone to develop T2DM.

Kinetic and thermodynamic investigation of the removal of alizarin red dye using silica-supported nanoscale zero-valent iron particles.

Alizarin red (ARS) dye is a persistent and toxic pollutant in aquatic environments, posing a significant environmental threat. Among various treatment technologies, adsorption offers a practical and highly efficient method for dye removal. This study investigates the application of silica-supported nanoscale zero-valent iron (nZVI) particles as adsorbents for the removal of ARS dye, with a focus on evaluating the adsorption kinetics and thermodynamic behavior of the process.

Nerve transfer to musculocutaneous for elbow flexion restoration in brachial plexus injury (Ulnar and/or Median vs. Intercostal): A systematic review and meta-analysis of comparative studies.

Background: Nerve transfers are a cornerstone in the surgical management of traumatic brachial plexus injuries (BPIs) to restore elbow flexion. Common donor nerves include intraplexal sources like the ulnar and median nerves (fascicular transfers) and extraplexal sources like the intercostal nerves (ICNs). Despite the widespread use of both techniques, the optimal donor nerve remains a subject of debate.

Bacterial cellulose doped with ZnO as a multifunctional bioactive platform for curcumin and propolis immobilization: synthesis, characterization, and wound healing potential.

Bacterial cellulose (BC)-based dressings exhibit favorable hydrogel characteristics, including high biocompatibility, moisture regulation, and mechanical adaptability, making them suitable candidates for biomedical applications. In this study, an integrated approach was employed to develop multifunctional, bioactive bionanocomposites. A cellulose-producing bacterial strain, Limosilactobacillus fermentum 6BC (accession number OM978241.