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The nonlinear strain response of soft material-based snap-through systems enables amplified and accelerated force output. However, efficiency of snap-through energy release is challenging to improve because of the inherent trade-off between initial curvature and stiffness. Here, spatial programming of stiffness variation in the azobenzene-functionalized liquid-crystalline polymer (Azo-LCP) addresses this limitation and achieves efficient photomechanical jumping. Introduction of stiffness mismatch induced localized curvature, which preserved the initial curvature and simultaneously enhanced photomechanical strain responsivity. By programming for symmetry of stiffness variation, we achieved directional or vertical jumping via strategic placement of the rigid region, with corresponding stress accumulation behaviors corroborated by finite element simulations. Integration of patterned stiffness variation with geometric asymmetry enabled both vertical and horizontal jumping within a single structure, without compromising performance. This dual-mode jumper also demonstrated sequential and consecutive jumps under continuous light exposure.
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http://dx.doi.org/10.1126/sciadv.adx8301 | DOI Listing |
J Am Chem Soc
September 2025
Department of Chemistry and Biochemistry, UC San Diego, La Jolla, California 92093, United States.
Chemical imaging holds great promise for chemical, materials, and biological applications. However, its contrast often relies on subtle spectral differences arising from molecular-level changes. Here, we introduce label-free chemical imaging based on bond-specific coherent interference, which is highly sensitive to nanoscopic structural variations in collagen fibers.
View Article and Find Full Text PDFBone
September 2025
Department of Mechanical Engineering, Texas A&M University, 3123 TAMU, College Station, TX, 77843, United States of America; School of Engineering Medicine, Texas A&M University, 1020 Holcombe Blvd, Houston, TX 77030, United States of America. Electronic address:
Breast, prostate and lung cancer cells frequently metastasize to bone, leading to disruption of the bone microstructure. This study utilized mechanical testing with micro-CT imaging, digital volume correlation (DVC), and atomic force microscopy (AFM) nanomechanical testing to examine the mechanical property variations in mouse long bones (tibia) with metastatic lung cancer cell involvement, spanning from the whole-bone scale to the microstructural level. In addition, we also investigated how metastatic invasion alters the morphology of hydroxyapatite nanocrystals in bone at the nanometer scale.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
Smart Materials, NanoSYD, Mads Clausen Institute, University of Southern Denmark, Alsion 2, Sønderborg, DK-6400, Denmark.
This study presents a comprehensive framework combining Selective Laser Melting (SLM) of Titanium (Ti64) alloys, finite element simulation, and artificial intelligence (AI) to advance orthopedic implants' design and predictive evaluation. Dense Ti64 specimens are fabricated using ten distinct SLM parameter sets to explore the effects of volumetric energy density (VED) on mechanical behavior, porosity distribution, and microstructural integrity. Optimal VED ranges are identified to balance defect minimization and mechanical performance, with porosity levels strongly influencing tensile strength and Young's modulus.
View Article and Find Full Text PDFBone Joint Res
September 2025
Department of Orthopedics, Luzhou Key Laboratory of Orthopedic Disorders, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Aims: Intervertebral disc degeneration (IDD) and sagittal-oriented articular processes can restrict motility and increase stiffness of the motion segment, potentially causing compensatory stress and higher motility in adjacent segments. It is unclear if these factors trigger IDD progression in adjacent segments. This study aimed to elucidate this using functional MRI, and identify biomechanical mechanisms with a validated numerical model.
View Article and Find Full Text PDFSci Adv
September 2025
Department of Mechanical Engineering and Material Science, Duke University, Durham, NC 27708, USA.
Assessing the mechanical properties of soft tissues holds broad clinical relevance. Advances in flexible electronics offer possibilities for wearable monitoring of tissue stiffness. However, existing technologies often rely on tethered setups or require frequent calibration, restricting their use in ambulatory environments.
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