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http://dx.doi.org/10.1007/s12098-025-05709-1 | DOI Listing |
BMJ Case Rep
September 2025
Department of Clinical Neurology, Tbilisi State Medical University, Tbilisi, Georgia.
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem syndrome marked by punctate 'pepper-and-salt' enhancement on MRI and corticosteroid responsiveness. Evidence suggests that CLIPPERS may represent a cancer-related immune reaction, occurring before tumour detection, in association with active malignancy or after treatment. We report the first case associated with papillary thyroid carcinoma (PTC).
View Article and Find Full Text PDFInflamm Res
September 2025
Department of Trauma Surgery, Emergency Surgery and Surgical Critical, Tongji Trauma Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Background: Severe polytrauma is one of the leading causes of death and disability worldwide. Hyperferritinemia is increasingly recognized as a biomarker of critical illness, yet its prognostic significance in polytrauma remains underexplored. This multicenter study investigates the temporal dynamics of serum ferritin in polytrauma patients and its association with systemic inflammation, organ dysfunction, and mortality.
View Article and Find Full Text PDFWorld J Hepatol
August 2025
Department of Internal Medicine, University of Health and Sciences Antalya Training and Research Hospital, Antalya 07050, Türkiye.
This letter offered commentary on the recently published article by Wang that investigated the relationship between iron metabolism disorders and sepsis-associated liver injury (SALI). The original study identified serum iron and total iron-binding capacity as potential predictive markers of SALI, contributing important insights to critical care hepatology. In this correspondence several methodological considerations that may influence the interpretation and generalizability of the findings were discussed.
View Article and Find Full Text PDFKidney Med
September 2025
National Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Clinical research and Data management, Center of
Rationale & Objective: Lymphopenia may have a potential mechanism on the development of acute kidney injury (AKI) after respiratory virus infection but has never been revealed. We aimed to investigate the relationship between lymphopenia and AKI in patients hospitalized with respiratory virus infections.
Study & Design: A single-center and retrospective cohort study.
J Clin Exp Hepatol
August 2025
Department of Radiodiagnosis, All India Institute of Medical Sciences, Patna, India.
Background: Extra-pulmonary tuberculosis is associated with a higher risk of drug-induced liver injury (DILI) with antituberculosis treatment (ATT). Nevertheless, hepatic dysfunctions in some patients can also regress to normalization due to hepatic adaptation (HA). Prospective data specifically addressing these issues in patients with abdominal tuberculosis (ATB) is lacking.
View Article and Find Full Text PDF