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Sustained amplified stimulated emission (ASE) under continuous-wave (cw) excitation is a prerequisite for any new gain material being developed for lasing applications. Despite the great success achieved in colloidal quantum dot (QD) lasers, the cw light amplification is hampered by the high pump threshold and thermal effects of QD solids. Herein, the first-ever cw ASE and lasing from QDs relevant for practical implementations are realized by adopting the microfluidic dot-in-matrix design. Leveraging on the transient and steady-state gain spectroscopy, it is demonstrated that the high-concentration dispersed QDs with a gain feature customized for cw pumping render the low pump threshold (≈340 W cm). Meanwhile, the QD micro-liquids effectively dissipate the heat arising from the nonradiative multi-carrier recombination. As such, the unprecedented two-band cw ASE and long-lasting cw lasing with coherent output beam are realized. The findings open the door to practical QD lasers and may unlock new possibilities in optofluidics and optoelectronics.
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http://dx.doi.org/10.1002/adma.202509457 | DOI Listing |
ACS Appl Mater Interfaces
September 2025
Research Center for Nano-Biomaterial, Analytical and Testing Center, Sichuan University, Chengdu 610065, China.
Regeneration of infected bone defects (IBDs) requires biomaterials capable of dynamically coordinating antimicrobial, anti-inflammatory, and osteogenic functions. Overcoming the spatiotemporal mismatches in treating IBDs remains a critical challenge. Here, we designed a temporally controlled therapy based on gelatin methacrylate (GelMA)-based nanocomposite hydrogels (GCS) coembedded with sulfur quantum dots (SQDs) nanoenzymes and calcium-phosphorus oligomers (CPOs.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
School of Chemistry & Materials Engineering, Fuyang Normal University, Fuyang 236037, China.
Halide perovskite quantum dots (QDs) have demonstrated outstanding performance in light-emitting applications. However, the performance of blue perovskite QDs lags far behind that of their red and green counterparts, especially those with color coordinates approaching (0.131, 0.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
The Associated Laboratory for Green Chemistry (LAQV) of the Network of Chemistry and Technology (REQUIMTE) - the Portuguese Research Centre for Sustainable Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313, Porto, Portugal. Electronic address:
Background: When using semiconductor quantum dots (QDs) for single-analyte sensing, recognition is commonly achieved through interactions with capping ligands attached to the QDs surface. These ligands form an organic layer that provides stability in solution and assures selectivity by binding the target analyte via surface functional groups. However, a common analytical challenge arises in the subsequent stage of the QD-based sensing scheme.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Guangxi Key Laboratory of Natural Polymer Chemistry and Physics, Key Laboratory of Nanobiosensor Analysis, College of Chemistry and Materials, Nanning Normal University, Nanning, 530001, PR China. Electronic address:
Background: Hexavalent chromium ions (Cr(VI)), a notorious toxic heavy metal pollutant with proven carcinogenicity, endangers human health and the environment. Meanwhile, l-ascorbic acid (L-AA), a vital biological antioxidant, has abnormal levels closely tied to various diseases. Developing efficient synchronous detection methods for these two key analytes is of great value in clinical and environmental monitoring.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
September 2025
Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA 19104, USA. Electronic address:
The clinical demand for safer, more precise, and functionally versatile imaging tools has intensified with the increasing complexity of disease diagnosis and management. Despite major strides in imaging technologies such as MRI, CT, USG, and PET/SPECT, many modalities are grappled by issues including low specificity, high systemic toxicity of contrast agents, and limited ability to provide real-time functional data. Dreaded by these shortcomings, nanotechnology-based approaches such as liposomes, quantum dots (QDs), polymeric nanoparticles (NPs), gold NPs, lipid NPs, and metallic NPs have emerged as promising alternatives.
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