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Adhesive small bowel obstruction (ASBO) during pregnancy is a critical condition that remains understudied. This study aimed to address management challenges of ASBO in pregnancy by evaluating the dual diagnostic and therapeutic role of gastrografin. We retrospectively analyzed medical records of pregnant patients with ASBO admitted between September 2018 and September 2023. Patients were categorized into conventional treatment or gastrografin groups based on received therapy. The groups showed no significant differences in demographics, baseline characteristics, or adverse events. However, the gastrografin group demonstrated superior outcomes, including a higher conservative treatment success rate, reduced need for surgery, shorter hospital stays, lower medical costs, and enhanced diagnostic utility. Gastrografin appears relatively safe in pregnancy, with its effective therapeutic action and precise diagnostic capability proving instrumental in managing ASBO.
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http://dx.doi.org/10.1038/s41598-025-11777-2 | DOI Listing |
J Chromatogr A
September 2025
College of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Synthetic cathinones (SCs) are drugs of abuse that act on the central nervous system, producing psychoactive effects similar to those of amphetamines. Their greater accessibility compared with the traditional amphetamine-type stimulants has contributed to their increasing popularity in recent years. The analysis of SCs in biological samples is essential for documenting their consumption.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
School of Light Industry and Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address:
The emergence of special scenarios involving small-sized penetrating wounds has imposed stricter performance requirements on shape-recovery hemostatic materials, particularly regarding their shape fixity and water-triggered shape recovery efficiency. Herein, an efficient shape-recovery sponge dressing with high shape fixity and high-speed liquid absorption, designated as CQT, was developed by integrating a sieve structure with the rough surface coating. The sieve structure, characterized by microporous structures on macroporous walls, enhanced the multi-level and connectivity of the overall pore network, which could improve compressive fixity via enhancing the energy dissipation required for rebound and enabled efficient shape recovery through augmented capillary action during fluid absorption.
View Article and Find Full Text PDFTissue Eng Regen Med
September 2025
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.
Background: Endometrial damage is a critical factor contributing to infertility, particularly in women with refractory thin endometrium or intrauterine adhesions. Therefore, developing innovative therapeutic strategies for endometrial regeneration is essential. This study evaluates the regenerative potential of endometrial stromal cell (EMSC) injection and EMSC-loaded patch application in a mouse model with ethanol-induced endometrial damage.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Biomedical Engineering, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, 210023, China.
Heat shock protein 70 (HSP70) represents a critical barrier to effective mild-temperature photothermal therapy (MPTT), limiting its clinical utility in aggressive cancers like triple-negative breast cancer (TNBC). While small interfering RNA (siRNA)-mediated HSP70 suppression offers a promising solution, optimal timing for this therapeutic combination remains unexplored. Here, it is demonstrated that precisely timed administration significantly enhances MPTT efficacy through systematic temporal characterization of HSP70 expression dynamics.
View Article and Find Full Text PDFInt J Stroke
September 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: Endothelial inflammation is involved in cerebral small vessel disease (CSVD) pathogenesis. Vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) are biomarkers of endothelial inflammation.
Aims: This study investigated association of VCAM-1 and ICAM-1 with presence of CSVD and CSVD burden.