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In recent years, nanomedicine has provided several high-performance tools for overcoming biomedical challenges, resulting in numerous patents [...].
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953327 | PMC |
http://dx.doi.org/10.3390/biomedicines11020399 | DOI Listing |
Adv Drug Deliv Rev
September 2025
State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200032, China; Shanghai Key Laboratory of Cancer System Regulation and Clinical Translation, Jiading District Central Hospital, Renji Hospital J
DNA exhibits remarkable versatility, which is attributed to its inherent molecular recognition capabilities, programmable sequences, and excellent biocompatibility. Among its various topological forms, branched DNA (bDNA), including Y-shaped DNA (Y-DNA), X-shaped DNA (X-DNA), etc., stands out as a fundamental building block for fabricating functional DNA-based materials and has demonstrated great promise across diverse applications in recent years.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, 212013, PR China. Electronic address:
Aptamers are single-stranded DNA or RNA oligonucleotides that can bind to specific target molecules with high affinity and specificity. Fluorescence DNA aptamer-based biosensors (aptasensors) have emerged as powerful analytical tools for detecting diverse targets, ranging from food contaminants to disease biomarkers, owing to their exceptional specificity, high sensitivity, and cost-effectiveness. This review systematically summarizes recent advances in the design strategies of fluorescence aptasensors, focusing on three key approaches: (1) fluorescence resonance energy transfer-based signal amplification, (2) nanomaterial-enhanced probes, and (3) multi-channel platforms for simultaneous detection.
View Article and Find Full Text PDFEnviron Pollut
September 2025
Hubei Key Laboratory of Wetland Evolution & Ecological Restoration, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geog
Tire microplastics (TMPs) represent a major contributor to microplastic pollution, posing threats to aquatic ecosystems. As carbon-rich substrates, TMPs influence microbial colonization and ecological functions. This study investigates the impacts of pristine (P-TMPs) and scrap (S-TMPs) TMPs from the same brand on microbial communities within the tire-plastisphere.
View Article and Find Full Text PDFBiosens Bioelectron
September 2025
School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address:
Liquid-phase suspension array technology (SAT), based on optically encoded microspheres, overcomes limitations of traditional enzyme-linked immunosorbent assay (ELISA) and chemiluminescence detection techniques via meeting high-throughput and multiplexing demands in biosensing and diagnosis. It demonstrates significant advantages in terms of accuracy, speed, sensitivity, and multiplex detection capabilities, and has become an emerging research hotspot in the field of luminescent immunodiagnostics. With rapid advancement of nanotechnology and multi-functional nanomaterials, liquid-phase suspension array chips have achieved remarkable progresses in multiplex analysis capacity, encoding capacity, encoding efficiency, detection sensitivity, decoding methods, and application fields.
View Article and Find Full Text PDFChem Rec
September 2025
College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin, 150040, P. R. China.
MXene-based peroxidase (POD)-like nanozymes demonstrate significant potential in biomedical applications due to their 2D structure, tunable catalytic activity, and interfacial effects. This review summarizes recent advances in MXene-POD nanozyme design, focusing on interfacial effects modulation via external stimuli (e.g.
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