Symmetry-breaking-engineered in-plane bulk photovoltaic effect in van der Waals WS/CrOCl heterostructure.

The bulk photovoltaic effect (BPVE), arising from symmetry breaking, has potential to attain conversion efficiencies which surpass Shockley-Queisser limit. Here, we achieve in-plane BPVE in WS/CrOCl heterostructure, attributed to broken-symmetry interfaces by stacking the WS onto anisotropic CrOCl. The breaking symmetry is evidenced by the asymmetric second harmonic generation and angle dependent Raman spectra.

Clinical characteristics of 415 patients with obstructed hemivagina and ipsilateral renal anomaly syndrome: A nationwide multicenter retrospective study.

Background: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare congenital genital tract anomaly that severely impacts quality of life and fertility in female adolescents. Most of the publications on OHVIRA have been case reports or small retrospective studies, and the clinical characteristics of this extremely rare anomaly have not been well documented.

Objective: To determine the clinical characteristics of OHVIRA, including its symptoms, anatomic features, concomitant malformations, surgeries, endometriosis and other complications according to subtype in a large nationwide cohort.

High efficiency and broadly wavelength-tunable mid-infrared nanosecond erbium-doped fiber laser pumped at ∼1.7 μm.

We demonstrate a high efficiency and broadly wavelength-tunable nanosecond mid-infrared (mid-IR) erbium (Er)-doped fluoride fiber laser pumped at ∼1.7 μm experimentally. In the continuous-wave operation regime, the mid-IR fiber laser output with a slope efficiency of approximately 40% has been obtained with a tuning range 143 nm spanning from 2695 nm to 2838 nm and a linewidth of 0.

Genetically predicted circulating immune cells and cytokines reveal the causal role of immune factors on female infertility: a two-sample mendelian randomization study.

Objectives: Previous studies suggested that immune factors may play critical roles in female infertility, but their causal links remain unclear. To address this gap, this study employs the Mendelian randomization (MR) to delineate the causal association between circulating immune factors and female infertility.

Methods: This study employed summary-level data from three genome-wide association studies (GWAS) encompassing 731 peripheral immune cell signatures, 41 circulating cytokines, and five female infertility phenotypes to reveal the causal relationship between immune factors and female infertility.

Improvement of Photocatalytic CO Reduction with Conjugated Organic Polymers by Rational Modulation of Donor, Acceptor and Bonding Method.

The use of metal-free catalysts to convert CO into valuable chemicals is very challenging. Here, we synthesized a conjugated organic polymer (TpTf-1) featuring 2,4,6-Triphenyl-1,3,5-Triazine as the acceptor unit, triphenylamine as the donor unit, and vinylidene bond as the linkage. The local structure of donor-acceptor (D-A) forms an intramolecular electric field that can promote the separation of photogenerated electrons and charges, meanwhile, the vinylidene bond can further change the charge distribution to promote exciton dissociation.

De novo urinary incontinence and lower urinary tract symptoms after colpocleisis: A single-center prospective study.

Background: Colpocleisis is one of traditional surgical procedures for elderly and frail women with advanced pelvic organ prolapse. The occurrence of de novo urinary incontinence following colpocleisis was considered to impair the postoperative quality of life. The incidence of de novo urinary incontinence after colpocleisis has been reported to be ranging from 6.

Clinical features and prognostic factors analysis of intravenous leiomyomatosis.

Background: The treatment and prognostic factors of intravenous leiomyomatosis (IVL) remain lacking systematic evidence.

Methods: A retrospective study was conducted on IVL patients from the Qilu Hospital of Shandong University, and IVL cases were published in PubMed, MEDLINE, Embase and Cochrane Library databases. Descriptive statistics were used for the basic characteristics of patients.

Assessment of prognostic and reproductive outcomes of omentectomy for patients with clinically apparent early-stage (I, II) malignant ovarian germ cell tumours: A multicentre retrospective study.

Objective: This study assessed the effect of omentectomy on the prognosis and fertility in patients with clinically early-stage (I, II) malignant ovarian germ cell tumours (MOGCT).

Design: A retrospective multicentre study.

Setting: Four university teaching hospitals in China.

Legacy and emerging persistent organic pollutants in the marginal seas of China: Occurrence and phase partitioning.

Emerging per-and polyfluoroalkyl substances (PFASs) and traditional organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (PAHs) in the marginal seas of China were analyzed to study the occurrence, transport and phase partitioning. The influence of organic carbon (OC) and element carbon (EC) on particulate emerging pollutants in seawater was studied for the first time. The concentrations of PFASs, OCPs and PAHs in the seawater (dissolved phase plus particulate phase) ranged from 1.

Hectowatt-level GHz burst-mode all-fiber laser based on dissipative soliton resonance.

We demonstrate a high power Yb-doped burst-mode all-fiber laser system operating at GHz intra-burst repetition rate. To our knowledge, it is the first report utilizing dissipative soliton resonance (DSR) to generate tunable burst-mode rectangular pulses. Due to the tunable duration and the rapid rise/fall time for DSR pulses, a 1-10 ns adjustable burst pulse duration is achieved.

HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.

Ovarian cancer is the most lethal gynecological malignancy. Recurrence and chemoresistance are tough challenges leading to poor prognosis. HJURP is a molecular chaperone of CENP-A, which is associated with aggressive progression in multiple tumors.

Loss of Krüppel-like factor 9 facilitates stemness in ovarian cancer ascites-derived multicellular spheroids via Notch1/slug signaling.

The ascites that develops in advanced OC, both at diagnosis and upon recurrence, is a rich source of multicellular spheroids/aggregates (MCSs/MCAs), which are the major seeds of tumor cell dissemination within the abdominal cavity. However, the molecular mechanism by which specific ascites-derived tumor cells survive and metastasize remains largely unknown. In this study, we elucidated cancer stem cell (CSC) properties of ascites-derived MCSs, concomitant with enhanced malignancy, induced EMT, and low KLF9 (Krüppel-like factor 9) expression, compared with PTCs.

FBLN5 is targeted by microRNA‑27a‑3p and suppresses tumorigenesis and progression in high‑grade serous ovarian carcinoma.

High-grade serous ovarian carcinoma (HGSOC) is one of the most lethal gynecological malignancies; however, the precise molecular mechanisms have not been fully characterized. Fibulin‑5 (FBLN‑5) is an extracellular matrix (ECM) glycoprotein, and plays a crucial role in maintaining the stability of ECM structures, regulating cell proliferation and tumorigenesis. In the present study, the expression of FBLN‑5, as determined by western blot analysis and immunohistochemistry, was significantly increased in normal fallopian tube (FT) samples compared with that in HGSOC samples, and decreased FBLN5 expression was associated with unfavorable prognosis of HGSOC.

Occurrence and partitioning behavior of per- and polyfluoroalkyl substances (PFASs) in water and sediment from the Jiulong Estuary-Xiamen Bay, China.

Twenty-four per- and polyfluoroalkyl substances (PFASs) were analyzed in water and sediment from the Jiulong Estuary-Xiamen Bay to study their seasonal variations, transport, partitioning behavior and ecological risks. The total concentration of PFASs in water ranged from 11 to 98 ng L (average 45 ng L) during the dry season, 0.19-5.

Ultra-efficient, 10-watt-level mid-infrared supercontinuum generation in fluoroindate fiber.

A 10-watt-level mid-infrared supercontinuum (SC) spanning 0.8-4.7 μm with ultra-high-power conversion efficiency is generated in a piece of fluoroindate (InF) fiber.

All-fiber wavelength-tunable Tm-doped fiber laser mode locked by SESAM with 120 nm tuning range.

We demonstrate an all-fiber widely wavelength-tunable thulium-doped fiber laser (TDFL) mode locked by a semiconductor saturable absorber mirror (SESAM). The tuning range spans 121 nm, from 1862 nm to 1983 nm. The central wavelength is tuned by a grating-based tunable filter in the ring laser cavity.

Mode-locked ytterbium-doped fiber laser based on topological insulator: Bi₂Se₃.

We demonstrated an all-normal-dispersion Yb-doped mode-locked fiber laser based on Bi₂Se₃ topological insulator (TI). Different from previous TI-mode-locked fiber lasers in which TIs were mixed with film-forming agent, we used a special way to paste a well-proportioned pure TI on a fiber end-facet. In this way, the effect of the film-forming agent could be removed, thus the heat deposition was relieved and damage threshold could be improved.

High-repetition-rate Q-switched fiber laser with high quality topological insulator Bi₂Se₃ film.

We demonstrated a high-repetition-rate Q-switched fiber laser with topological insulator Bi₂Se₃ absorber. The absorber was made into a film structure by spin-coating method using few-layer Bi₂Se₃ nano-platelets which had regular shape. The uniform film had a low saturable optical intensity of 11 MW/cm(2), which is the lowest saturable optical intensity in the saturable absorbers made by topological insulator till now.