Role of GATM/creatine as energy reserves in the poll gland and rutting activities in male Bactrian camel.

In the breeding season, male Bactrian camels (Camelus Bactrianus) secrete a large amount of pale-yellow watery secretions with a characteristic odor from the poll glands and spread urine by wagging their tails, which can induce estrus and mating in female camels. However, the compositions of the urine and poll glands secretions during the breeding season are poorly understood. Thus, we investigated the unique secretions of poll glands and identified key metabolites during the breeding season.

Role of Adiponectin in Regulating Cytokines and Its Contribution to the Occurrence and Progression of Clinical Mastitis in Holstein Cows.

Cytokines are crucial in various physiological and pathological processes, especially in inflammatory diseases in mammals. However, the comprehensive identification of cytokines and their potential regulatory functions in the mammary glands of Holstein cows suffering from clinical mastitis (CM) remains only partially understood. This study aimed to systematically identify biological processes (BPs) and differentially expressed proteins (DEPs) associated with cytokines and to explore their functions through the analysis of previously obtained data from data-independent acquisition (DIA) proteomics.

Identification and characterization of microRNAs in the liver of yak (Bos grunniens) associated with energy deficiency at high-altitude.

Objective: MicroRNAs (miRNAs) are small non-coding RNAs that regulate various biological processes including systemic metabolism and energy homeostasis. Comprehending hepatic functional adaptations is critical for yak (Bos grunniens) cattle as these herds typically suffer from malnutrition during the most of winter grazing seasons.

Methods: To enhance the understanding of miRNA mediated post-transcriptional regulation in the context of energy deficiency in yaks, the miRNA transcriptomes of liver were profiled using deep sequencing analyses.

Exploring the factors influencing the carbon sink function of coastal wetlands in the Yellow River Delta.

Understanding the mechanisms of the coastal wetland ecosystem carbon sink function is crucial for adapting to, mitigating, and predicting global climate change. Landscape metrics and Carnegie Ames Stanford Approach (CASA) model were used to quantify the spatiotemporal patterns of soil organic carbon (SOC) and vegetation carbon sequestration (VCS) in the Yellow River Delta (YRD). GeoDetector model was used to explore the effects of various factors influencing VCS.

Functional analysis of microorganisms and metabolites in the cecum of different sheep populations and their effects on production traits.

The purpose of this study was to investigate the effects of intestinal microbiota on the growth and production performance of different groups of sheep, focusing on the role of cecal microbiota in regulating intestinal function, enhancing digestion and absorption, and improving feed utilization. The production performance of MG × STH (Mongolia × Small Tailed Han) F1 hybrids and purebred STH (Small Tailed Han) sheep by measuring various factors, including enzyme activities and VFAs (volatile fatty acids), to analyze changes in cecal fermentation parameters across different sheep groups. Metagenomic and metabolomic sequencing combined with bioinformatics to analyze the cecal contents of the two sheep populations.

Bispecific CAR-T cells targeting CD19/20 in patients with relapsed or refractory B cell non-Hodgkin lymphoma: a phase I/II trial.

Non-Hodgkin lymphoma (NHL) is a common malignancy in the hematologic system, and traditional therapy has limited efficacy for people with recurrent/refractory NHL (R/R NHL), especially for patients with diffuse large B cell lymphoma (DLBCL). Chimeric antigen receptor (CAR) T-cell therapy is a novel and effective immunotherapy strategy for R/R hematopoietic malignancies, but relapses can occur due to the loss of CAR-T cells in vivo or the loss of antigen. One strategy to avoid antigen loss after CAR-T cell therapy is to target one more antigen simultaneously.

Verification of Key Target Molecules for Intramuscular Fat Deposition and Screening of SNP Sites in Sheep from Small-Tail Han Sheep Breed and Its Cross with Suffolk.

Intramuscular fat (IMF) is vital for meat tenderness and juiciness. This study aims to explore the IMF deposition mechanism and the related molecular markers in sheep. Two populations, Small-tail Han Sheep (STH) and STH × Suffolk (SFK) F (SFK × STH), were used as the research object.

Favorable response of a patient with primary B/myeloid mixed phenotype acute Leukemia to CD19-CAR-T: Case report and literature review.

Rationale: Mixed phenotype acute leukemia (MPAL) is a rare and heterogeneous type of leukemia known for its poor prognosis. The optimal treatment strategy for this condition currently lacks consensus, leaving uncertainty in its management. Nonetheless, a potential therapeutic option for patients with refractory MPAL who express target antigens is donor-derived chimeric antigen receptor T (CAR-T) cell therapy.

Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer.

Background: Breast cancer, the most common malignancy in women worldwide, has been proven to have both altered plasma cell-free DNA (cfDNA) methylation and fragmentation profiles. Nevertheless, simultaneously detecting both of them for breast cancer diagnosis has never been reported. Moreover, although fragmentation pattern of cfDNA is determined by nuclease digestion of chromatin, structure of which may be affected by DNA methylation, whether cfDNA methylation and fragmentation are biologically related or not still remains unclear.

Correction: Mechanistic study on NO reduction by sludge reburning in a pilot scale cement precalciner with different CO concentrations.

[This corrects the article DOI: 10.1039/C9RA04065J.].

Mechanistic study on NO reduction by sludge reburning in a pilot scale cement precalciner with different CO concentrations.

An experimental study on the effects of CO concentration on the release of reducing gases and the NO reduction efficiency by sludge reburning was carried out in a pilot scale cement precalciner. The results indicate that sludge reburning shows an ideal NO reduction activity. The best NO reduction efficiency of 54% is reached when the CO concentration is 25 vol%.

Data on species and concentration of the main gaseous products during sludge combustion to support the feasibility of using sludge as a flue gas denitration agent for the cement industry.

The dataset presented in this article is the supplementary data for the research article Fang et al., 2019 [1] and provided detailed data profile to support that sludge is an effective NO reducing agent, as reductive gas components produce during sludge combustion. The instantaneous concentrations of the main gaseous products during sludge combustion were detected by using Fourier transform infrared spectroscopy (FTIR, DX-4000, Gasmet Technologies).

Tuning the magneto-optical Kerr effect by the nanograting cross section.

The magneto-optical Kerr effect, especially the Kerr slope, is of great significance to magneto-optical devices. Herein, we developed a method to tune the magneto-optical effect by the nanograting cross section. Both the simulation and experiment confirm that the resonance strength of the plasmon can be modulated by the nanograting cross section, resulting in the large Kerr slope and Kerr rotation.

Ultrafast Orbital-Oriented Control of Magnetization in Half-Metallic La Sr MnO Films.

Manipulating spins by ultrafast pulse laser provides a new avenue to switch the magnetization for spintronic applications. While the spin-orbit coupling is known to play a pivotal role in the ultrafast laser-induced demagnetization, the effect of the anisotropic spin-orbit coupling on the transient magnetization remains an open issue. This study uncovers the role of anisotropic spin-orbit coupling in the spin dynamics in a half-metallic La Sr MnO film by ultrafast pump-probe technique.

Enhancing the figure of merit of refractive index sensors by magnetoplasmons in nanogratings.

The sensing performance of one-dimensional magnetic nanograting based on magnetoplasmons was investigated. The predictable Kerr reversal and enhancement are achieved in our experiment. The further result shows that the shift of the Kerr null point has a linear relationship with the surrounding refractive index in a wide range.

Security and efficiency enhancement of an anonymous three-party password-authenticated key agreement using extended chaotic maps.

Recently, Lu et al. claimed that Xie et al.'s three-party password-authenticated key agreement protocol (3PAKA) using chaotic maps has three security vulnerabilities; in particular, it cannot resist offline password guessing attack, Bergamo et al.

The Long Noncoding RNA LnRPT Is Regulated by PDGF-BB and Modulates the Proliferation of Pulmonary Artery Smooth Muscle Cells.

Pulmonary artery hypertension (PAH) is a rare and fatal disorder that involves extensive remodeling of the pulmonary arteries mediated by hyperproliferation of pulmonary artery smooth muscle cells (PASMCs). Aberrant platelet-derived growth factor (PDGF) activity can lead to hyperproliferation of PASMCs; however, little is known about the role of long noncoding RNA (lncRNA) in this process. Using RNA sequencing, we identified 725 lncRNAs in rat PASMCs, 95 of which were expressed differentially in response to PDGF-BB treatment.

miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.

Myogenesis involves myoblast proliferation and differentiation to myocytes, followed by fusion and hypertrophy to form myotubes during muscle development. Increasing evidence showed that microRNAs (miRNAs) play important roles in the regulation of myogenesis. We have previously revealed that miR-34b is steadily increased during this process.

MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.

Myogenic differentiation, which occurs during muscle development, is a highly ordered process that can be regulated by E2F transcription factors. Available data show that E2F3b, but not E2F3a, is upregulated and required for myogenic differentiation. However, the regulation of E2F3b expression in myogenic differentiation is not well understood.

Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.

Myocytes withdraw from the cell cycle to differentiate during muscle development. Given the capacity of microRNAs (miRNAs) to regulate gene expression during development, we screened for miRNAs that were associated with muscle development. S-Poly(T) Plus analysis of 273 miRNAs in porcine longissimus dorsi muscles revealed 14 miRNAs that were strongly upregulated with age of postnatal muscle development , including miR-195 and miR-497.

Biometrics based authentication scheme for session initiation protocol.

Many two-factor challenge-response based session initiation protocol (SIP) has been proposed, but most of them are vulnerable to smart card stolen attacks and password guessing attacks. In this paper, we propose a novel three-factor SIP authentication scheme using biometrics, password and smart card, and utilize the pi calculus-based formal verification tool ProVerif to prove that the proposed protocol achieves security and authentication. Furthermore, our protocol is highly efficient when compared to other related protocols.

Enhancement of magneto-optical Faraday effects and extraordinary optical transmission in a tri-layer structure with rectangular annular arrays.

The properties of optics and magneto-optical Faraday effects in a metal-dielectric tri-layer structure with subwavelength rectangular annular arrays are investigated. It is noteworthy that we obtained the strongly enhanced Faraday rotation of the desired sign along with high transmittance by optimizing the parameters of the nanostructure in the visible spectral ranges. In this system, we obtained two extraordinary optical transmission (EOT) resonant peaks with enhanced Faraday rotations, whose signs are opposite, which may provide the possibility of designing multi-channel magneto-optical devices.

Magneto-optical properties of one-dimensional orderly nanocorrugation made from magnetic quadrilayer films.

Magneto-optical (MO) Kerr effect and optical reflectance are investigated in the visible light region for one-dimensional orderly nanocorrugation of magnetic quadrilayer films. We find that the MO enhancement originates from the combined action between cavity effect and surface plasmon resonance. The coupling between surface plasmon polaritions and localized surface plasmons cannot only enhance the magnitude of Kerr angle, but also alter the sign of Kerr rotation.

[Numerical study on the performance effect of the ratio of long axis to short axis of upright polypropylene infusion bag].

The study aims to investigate the effect of the ratio of long axis to short axis (RLS) of upright polypropylene infusion bag on discharging process and to search the best RLS. Aiming at five different RLS (1. 5 : 1, 2 : 1, 3 : 1, 4 : 1 and 5 : 1, respectively) with the volume of 100 mL, 250 mL and 500 mL, respectively, based on finite element method, analyzing the variation of stress distribution, emptying rate, drugging space and steadiness coefficient, etc.