InSe-Based Sensors and Related Sensing Systems for NO Gas/Temperature Monitoring.

High-sensitivity, multiparameter sensing is increasingly critical for environmental monitoring and electronics. Existing sensing platforms struggle to integrate precise, rapid, and stable monitoring of parts per billion-level hazardous gases and temperature within a single miniaturized device. This study developed a novel sensor based on two-dimensional (2D) indium selenide (InSe), complemented by first-principles density functional theory calculations elucidating the layer-dependent NO adsorption mechanism.

Correction: The relationship between physical activity and Internet addiction among Chinese adolescents: exploring latent profile analysis and multi-level mediating mechanisms.

[This corrects the article DOI: 10.3389/fpsyg.2025.

3D-CT Study of Buccal Fat Pad Volume in Patients with Prominent Zygoma.

Objective: To compare the symmetry of bilateral buccal fat pad(BFP) volumes in patients with prominent zygomatic bones before surgery.

Methods: Fifty cosmetic female patients were selected and scanned using computed tomography. Based on the symmetry of the patients' zygomatic bones prior to surgery, they were divided into the Sym group and the Asym group.

MicroRNAs as Biotechnological Targets for Future Food Security and Agricultural Sustainability.

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression, playing key roles in plant growth, development, and stress responses. Their regulatory functions make miRNAs ideal targets for enhancing crop yield, quality, and stress tolerance using biotechnologies, such as transgenic overexpression and CRISPR/Cas genome editing. By targeting multiple genes, miRNAs address complex agricultural challenges effectively.

Clinical and genetic features of UNC13D deficiency with hypogammaglobulinemia.

Background: UNC13D deficiency is the most common form of familial hemophagocytic lymphohistiocytosis (FHL) in Asia. Hypogammaglobulinemia is a rare phenotype observed in both patients with FHL3 and sporadic hemophagocytic lymphohistiocytosis (HLH). Our observations suggest that UNC13D deficiency with hypogammaglobulinemia presents a distinct clinical phenotype compared to other HLH patients.

Structural basis of CAX1 autoinhibition by its amino-terminal domain in Arabidopsis thaliana.

Calcium homeostasis is tightly regulated due to the essential roles of calcium ions (Ca) in various cellular processes. CAX1 in Arabidopsis thaliana (AtCAX1) serves as a Ca/H exchanger transporting excess cytosolic Ca into the vacuole, which is modulated by kinase phosphorylation in response to diverse signals. However, the regulatory mechanism remains unclear.

Multiple biomarkers risk score for accurately predicting the long-term prognosis of patients with acute coronary syndrome.

Background: Biomarkers-based prediction of long-term risk of acute coronary syndrome (ACS) is scarce. We aim to develop a risk score integrating clinical routine information (C) and plasma biomarkers (B) for predicting long-term risk of ACS patients.

Methods: We included 2729 ACS patients from the OCEA (Observation of cardiovascular events in ACS patients).

A fully automatic knee subregion segmentation network based on tissue segmentation and anatomical geometry.

Aiming at the difficulty of knee MRI bone and cartilage subregion segmentation caused by numerous subregions and unclear subregion boundary, a fully automatic knee subregion segmentation network based on tissue segmentation and anatomical geometry is proposed. Specifically, first, we use a transformer-based multilevel region and edge aggregation network to achieve precise segmentation of bone and cartilage tissue edges in knee MRI. Then, we designed a fibula detection module, which determines the medial and lateral of the knee by detecting the position of the fibula.

Dimensionality and correlation effects in coupled carbon nanotube arrays.

Coupled one-dimensional (1D) conductor array has been proposed as a promising platform to explore the electronic correlation phenomena in higher dimensions and rich electronic phases; however, these architectures have been challenging to configure over the past few decades. Well-aligned semiconducting carbon nanotubes (CNTs) have been demonstrated as a promising channel material to construct ultra-scaled transistors for future integrated circuits, but their transport behaviors, especially the tunable dimensionality and electron-electron () interactions, remain elusive and are needed to explore the correlated electronic phases. Here, we experimentally realize a dimensional transition with controlled electronic correlationsusing coupled quantum wire arrays that contain well-aligned CNTs in a two-dimensional (2D) film.

Three-dimensional cephalometric analysis of morphological characteristics in children with bilateral craniofacial microsomia.

Purpose: Craniofacial microsomia (CFM), the second most common congenital craniofacial anomaly, is poorly characterized in bilateral cases because conventional cephalometry cannot accurately assess facial asymmetry. This study aims to characterize craniofacial morphology in children with bilateral CFM using three-dimensional (3D) cephalometric analysis.

Materials And Methods: A retrospective 3D cephalometric analysis was conducted on 8 bilateral CFM patients and 10 age-/sex-matched normal patients as controls.

Novel compound heterozygous MRTFA gene variants cause multiple dysfunctions of neutrophils and autoinflammation.

Background: Compound heterozygous mutations in the MRTFA gene have not been reported; the complete clinical phenotypic spectrum associated with MRTFA deficiency remains undefined. Whether such mutations can result in autoinflammatory manifestations is also yet to be determined.

Methods: Comprehensive analyses were conducted on a patient with novel compound heterozygous MRTFA variants, encompassing clinical data collection, genetic validation, and functional studies.

Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis.

The purpose of this study was to search for genes related to ros induced oxidative stress in osteoarthritis(OA) cartilage through bioinformatics analysis, and to verify the expression of related genes in articular cartilage of OA patients. OA expression data and ROS-related genes were downloaded from GEO (GSE51588, GSE117999) and Molecular Signatures Databases. The limma package in R language was used to screen differently expressed genes (DEGs) from the GEO databases.

Formation and sustenance mechanism of bacterial diversity in nutrient-deficient environment of indoor stadium.

Bacterial diversity has been found in indoor stadiums which can be considered as a specific nutrient-deficient environment (NDE), it remains a mystery and opens to new ideas why the bacterial diversity can be formed and maintained in NDE of indoor stadiums, since it is obvious to violate the famous competitive exclusion principle (CEP) in ecology. In the article, five most common genera, Pseudomonas, Acinetobacter, Exiguobacterium, Sphingobacterium, Chryseobacterium in indoor stadiums were selected and periodically sampled to supervise the dynamic characteristics of bacterial community. Based on quorum sensing (QS) and non-monotonic interspecific interaction (NMII) in combination with microbial ecology, clustering analysis and experimental observation, a new hypothesis was put forward to elucidate QS and NMII of substrate location information (SLI) mechanism driving bacterial community succession with high diversity in NDE of indoor stadium.

CRISPR meets AlphaFold: guiding SWEET10-enhanced oil production.

Enhancing seed oil content significantly benefits both human welfare and environmental sustainability. Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas) and artificial intelligence (AI) are transformative tools for crop trait improvement. A recent study by Wang and colleagues reported that AlphaFold-guided CRISPR genome editing of SWEET10 boosts oil contents, highlighting a breakthrough in precision crop engineering.

Unraveling historical genetic divergence and gene flow patterns between island (Taiwan) and mainland (China) of .

The disjunctive distribution of between Taiwan and mainland China provides a unique framework for understanding phylogeographic patterns and evolutionary processes in relict tree species. This study investigated the genetic diversity, population structure, and phylogeographic history of using microsatellite and chloroplast DNA markers. Analysis of 249 samples from nine populations revealed that Taiwanese populations possess higher genetic diversity with significant inbreeding, while mainland Chinese populations showed lower diversity and inbreeding levels.

Constructing relative spatial relationships of large-area objects using time-of-flight sensing and achieving multidimensional evaluation.

3D scanning can construct comprehensive information about objects. However, scanning scenes at the meter scale is costly and inefficient. For large-area objects with distinctive physical attributes or tasks emphasizing internal relational mapping, there is value in taking a few sampling points to establish the relative relationships of objects.

Radiomics models for predicting occult nodal metastasis in stage cT1a-bN0M0 lung adenocarcinoma: a multicenter study.

Background: Preoperative detection of occult nodal metastasis (ONM) is essential for treatment planning and prognostic evaluation in lung adenocarcinoma (LUAD). This study aimed to develop and validate radiomics models capable of predicting ONM in patients with stage cT1a-bN0M0 LUAD.

Methods: A total of 1,672 patients from six hospitals were enrolled and stratified into training (n=687), test (n=297) and external validation (n=688) sets.

Multiband Fast Spin Echo on portable low-field systems.

Purpose: To improve the SNR efficiency of Fast Spin Echo (FSE) using RF-encoded multiband imaging and to develop techniques that correct artifacts from non-Carr-Purcell-Meiboom-Gill (CPMG) magnetization arising from system imperfections.

Methods: Optimal refocusing pulse band phase modulations that satisfy the CPMG condition were calculated for different multiband factors. Fast recovery was used to enhance T2 contrast.

Genetic correlation and causation of craniofacial microsomia with 33 diseases in Asian populations: insights from large-scale genome-wide cross-trait analysis.

The primary aim of our study was to investigate the genetic correlations, colocalized genes, and causal relationships between craniofacial microsomia (CFM) and 33 diseases (including tumours and respiratory, heart, and kidney diseases). On the basis of extensive summary-level data from genome-wide association studies (GWASs), we evaluated the genetic linkage between CFM and a spectrum of 33 medical conditions using linkage disequilibrium score regression (LDSC). We employed PLACO to identify pleiotropic loci and genes associated with CFM and other diseases.

The role of adenoid hypertrophy in obstructive sleep apnea outcomes post-mandibular distraction osteogenesis in patients with craniofacial microsomia.

Study Objectives: Mandibular distraction osteogenesis (MDO) is recommended for children with craniofacial microsomia (CFM) and obstructive sleep apnea (OSA). However, its efficacy remains limited, with success rates of 36.4%-60%.

Fine-scale analysis of the cumulative and time-lagged effects of drought on vegetation in the Ili River Basin, Central Asia.

Under intensifying climate change, drought impacts on vegetation have become increasingly complex. Although the Ili River Basin is highly sensitive to drought, the underlying mechanisms of drought-vegetation interactions remain insufficiently understood. This study quantifies the cumulative, time-lagged, and dominant effects of drought on vegetation gross primary productivity (GPP) at the daily scale, and investigates their variations across land use types, wetness gradients, and seasons.

Glymphatic dysfunction in HIV: a resting-state fMRI biomarker linking cognitive impairment and immune suppression.

Objective: To investigate glymphatic dysfunction in people living with HIV (PLWH) and its associations with immunological status and cognitive function, utilizing the coupling strength of global blood-oxygen-level-dependent and cerebrospinal fluid (gBOLD-CSF).

Design: Retrospective study of 75 PLWH and 52 non-HIV controls undergoing neuropsychological tests and resting-state functional magnetic resonance imaging (rs-fMRI).

Methods: GBOLD-CSF coupling, Montreal Cognitive Assessment (MoCA) and seven cognitive domain scores were calculated.

The relationship between physical activity and Internet addiction among Chinese adolescents: exploring latent profile analysis and multi-level mediating mechanisms.

In recent years, adolescent Internet addiction has emerged as a pressing concern, undermining young people's psychological well-being and social functioning. Although regular physical activity is known to bolster adolescents' mental health, its direct and indirect protective effects against Internet addiction-and the psychosocial processes involved-remain insufficiently understood, particularly in terms of how these effects differ across subgroups identified via latent profile analysis. Given this, the present study, employing structural equation modeling (SEM), delineated the factor structures and predictive relationships among physical activity, family cohesion, prosocial behavior, and Internet addiction.

Decoding Hepatocellular Carcinoma Metastasis: Molecular Mechanisms, Targeted Therapies, and Potential Biomarkers.

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with metastasis representing a pivotal factor in poor prognosis and high fatality rates. This review offers a comprehensive examination of the key molecular events and regulatory mechanisms driving HCC metastasis, with a particular focus on genetic mutations, epigenetic alterations, and dysregulated signaling pathways. Special emphasis is placed on the role of three-dimensional genome structural remodeling in HCC initiation and metastatic progression.

Global, regional, and national burden of genitourinary cancers in 204 countries and territories, 1990-2021: a systematic analysis for the global burden of disease study 2021.

Background: Genitourinary cancers constitute a significant portion of the global cancer burden and have emerged as a prominent cause of cancer-related mortality. However, there remains a paucity of up-to-date statistical analyses that meticulously examine the global and national shifts in the epidemiology of genitourinary cancers. Our study aimed to provide a comprehensive understanding of the global distribution and progression of genitourinary cancers through analyses of the recently updated 2021 Global Burden of Disease (GBD) database.