High-Temperature Thermal Camouflage Device Considering Radiative Thermal Transfer from the Target.

Thermal camouflage technologies manipulate heat fluxes to conceal objects from thermographic detection, offering potential solutions for thermal management in high-power-density electronics. Most reported approaches are aimed at scenarios where the target is not a heat source; however, any target with a non-zero temperature emits thermal radiation described by the Stefan-Boltzmann law since the thermal radiation of an object is proportional to the fourth power of its temperature (T). To address this issue, this study proposes a thermal camouflage device that considers the influence of radiative thermal transfer from the target.

A novel immune-metabolic prognostic model stratifies survival and personalizes therapy in hepatocellular carcinoma.

Background: The etiology of HCC is multifactorial, with pathogenesis involving immune and metabolic pathways. This study developed a prognostic model based on immune- and metabolism-related genes (IMRGs) to improve personalized HCC management.

Methods: Transcriptomic data from HCC patients were obtained from TCGA (n = 377) and GEO (n = 115).

Investigation of Al Doping Effect on LVP Cathode: Structure Evolution and Magnetic Transition.

The determination of ion doping sites, doping amounts, and changes in the crystal and magnetic structures are fundamental and crucial issues that remain unclear in cation doped LiV(PO) (LVP) cathode for lithium-ion batteries. This study employed X-ray diffraction (XRD) and Rietveld refinements, Al/Li/V/P nuclear magnetic resonance (NMR) spectroscopy, superconducting quantum interference device (SQUID) measurements, and density functional theory (DFT) calculations to investigate the doping sites and amounts of Al, the long-range and short-range crystal structures, the electronic structure, and the possible changes in magnetism in a series of LiV2(1)Al(PO)/reduced graphene oxide composites (LVAP/C). The results demonstrate that the practical doping sites and amounts of Al, as well as the crystal and electronic structures, and magnetic characteristics, are affected by different ranges of Al doping amounts.

The triglyceride-glucose index associated with reduced risk of liver metastasis in pancreatic cancer.

Background: The triglyceride-glucose (TyG) index has emerged as a reliable surrogate marker for insulin resistance and is associated with multiple malignancies. However, its role in pancreatic cancer liver metastasis (PCLM) remains unclear. This study aimed to investigate the relationship between TyG index and PCLM and evaluate its predictive value for PCLM.

Donor liver natural killer cells ameliorate liver allograft rejection via inducing apoptosis of alloreactive CD8 T cells generating CD4CD25 regulatory T cells.

The roles of donor liver natural killer (NK) cells in allogeneic liver transplantation remains controversial. Herein, we investigated the effects of liver NK cells on liver allograft tolerance by using liver NK cells and allogeneic spleen T cell co-culture in vitro experiments and the rat orthotopic liver transplantation model. CD8 T cells exhibited higher apoptotic rate and up-regulated expression of CD95 molecules when co-cultured with allogeneic liver NK cells in vitro, indicating that liver NK cells might induce the apoptosis of CD8 T cells via CD95 in vitro.

PADI1 aggravates endoplasmic reticulum stress in trophoblast cells by inhibiting the FAK-ERK signaling pathway.

Preeclampsia (PE) is a multisystemic syndrome of pregnancy that seriously affects maternal and infant healthcare. Here, we identified PADI1 as an abnormally highly expressed gene in PE and investigated its effect on trophoblast cells. According to the analysis results from GEO datasets GSE186257 and GSE143953, PADI1 is highly expressed in the placental samples of PE patients.

Association between the gut microbiota and cystitis: A two-sample mendelian randomization study combined with the GEO database.

Background: Disturbances within the intestinal microbiota have emerged as a significant factor contributing to systemic inflammation, thereby rendering distant anatomical sites more vulnerable to various illnesses, including inflammatory conditions in the urinary tract such as cystitis. However, the causal relationship between dysbiosis of the gut microbiota and cystitis remains unclear. We sought to elucidate the causal relationship between the intestinal microbiota and cystitis employing Mendelian randomization (MR), offering insights into novel preventive and therapeutic strategies for managing cystitis.

Risk factors, prognostic factors, and nomograms for liver metastasis in stage T-T colorectal cancer patients from a population-based study.

Liver metastasis(LM) is the primary cause of mortality in patients with colorectal cancer. The incidence of liver metastasis in patients with stage T-T colorectal cancer is uncommon, and there is limited research available. While nomograms have been increasingly utilized in oncology, there is a lack of studies focusing on the diagnosis and prognostic assessment of liver metastasis in patients with stage T-T colorectal cancer.

Hyperthermic intraperitoneal chemotherapy plus SOX chemotherapy versus SOX chemotherapy alone in patients with gastric cancer and peritoneal metastasis: a phase II randomized clinical trial.

Background: The prognosis of patients with gastric cancer with peritoneal metastasis (GCPM) is exceedingly poor. This study evaluated the efficacy and safety of hyperthermic intraperitoneal chemotherapy (HIPEC) with paclitaxel combined with S-1 and oxaliplatin (SOX) in the treatment of GCPM.

Methods: Patients with pathologically confirmed primary gastric adenocarcinoma and laparoscopy-confirmed peritoneal metastasis were enrolled and randomized to receive either HIPEC plus SOX (HIPEC group) or SOX alone (SOX group).

The effect of rice and edible starch compound ratios, starch type, and rice nutrients on Burkholderia gladioli pathovar cocovenenans growth and bongkrekic acid production in wet rice noodles and starch products.

Bongkrekic acid (BA) toxin, produced by Burkholderia gladioli pathovar cocovenenans bacteria, has been implicated in foodborne illness outbreaks. BA poisoning is associated with rice noodle consumption; hence, this study investigated B. cocovenenans growth and BA production in wet rice noodles comprising varying starch ratios, starch types, rice nutrients, and saccharides.

Grid-Like Structured Sb@DNC Anode by Self-Sacrificial Etching for Fast and Durable Sodium Storage.

Alloying-type materials are promising anodes for sodium storage due to high specific capacities and appropriate redox potentials, but their practical application is impeded by rapid capacity decay from volume change during sodium ion insertion/extraction. Hence, a dual-type N-doped carbon-confined antimony (Sb) nanoparticle (Sb@DNC, where DNC contains an outer N-doped carbon armor and an inner N-doped grid-like carbon skeleton) anode material is fabricated via a self-sacrificial etching strategy to address this challenge. Specifically, the dual-type N-doped carbon matrix can prevent the agglomeration and precipitation of Sb particles, increase a large number of reactive active sites, alleviate severe volume expansion/contraction, and construct a highly interconnected electron/ion transport network.

Electrochemiluminescence sensor for organophosphorus pesticides based on the regulation of resonance energy transfer between negative charged gold nanorods and Ru(bpy).

Combined the electrostatic interaction of the negatively charged gold nanorods (AuNRs) (as acceptor) and Ru(bpy) (as donor), an electrochemiluminescence resonance energy transfer (ECL-RET) sensor was constructed and applied for the detection of organophosphorus pesticides (OPs). Negatively charged AuNRs were synthesized by modifying AuNRs with polystyrene sulfonate (PSS) firstly, which can bind to Ru(bpy) through electrostatic interaction so that the luminophore was absorbed by the acceptor, the resonance energy transfer occurred and only low ECL signal had been detected. Thiocholine can be produced by the hydrolysis process of acetylthiocholine (ATCh) with the help of acetylcholinesterase (AChE), which can bond with PSS-modified AuNRs (PSS-AuNRs) through gold-sulfur interaction, this caused the releasing of the adsorbed Ru(bpy) into the solution and resulting in the restoration of the ECL intensity.

Recurrent epithelioid angiomyolipoma of the adrenal gland: a case report and literature review.

Background: Epithelioid angiomyolipoma (EAML), a subtype of angiomyolipoma, is distinct. It has a biologic behavior of borderline tumor, a malignant tendency, and a risk of metastasis and recurrence. Adrenal EAML is very rare.

Molecular characteristics and immune microenvironment of gastrointestinal stromal tumours: targets for therapeutic strategies.

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours, arising mainly from the interstitial cells of Cajal (ICCs) of the gastrointestinal tract. As radiotherapy and chemotherapy are generally ineffective for GISTs, the current primary treatment is surgical resection. However, surgical resection is not choice for most patients.

Preparation, characterization, and liver targeting evaluation of a novel sustained-release brucine self-assembled micelle mediated by glycyrrhetinic acid.

Cancer is a serious threat to human life, health and social development. In recent years, nanomicelles, as an emerging drug carrier material, have gradually entered people's field of vision because of their advantages of improving bioavailability, maintaining drug levels, reducing systemic side effects and increasing drug accumulation at target sites. In this study, B-GPSG nano-micelles were prepared by film dispersion hydration method using brucine as model drug and glycyrrhetinic acid-polyethylene glycol-3-methylene glycol-dithiodipropionic acid-glycerol monostearate polymer as nano-carrier.

Enhancing antitumor efficacy of NIR-I region zinc phthalocyanine@upconversion nanoparticle through lysosomal escape and mitochondria targeting.

Accurately visualizing the intracellular trafficking of upconversion nanoparticles (UCNPs) loaded with phthalocyanines and achieving precise photodynamic therapy (PDT) using near-infrared (NIR) laser irradiation still present challenges. In this study, a novel NIR laser-triggered upconversion luminescence (UCL) imaging-guided nanoparticle called FA@TPA-NH-ZnPc@UCNPs (FTU) was developed for PDT. FTU consisted of UCNPs, folic acid (FA), and triphenylamino-phenylaniline zinc phthalocyanine (TPA-NH-ZnPc).

Unveiling the Synergy of Architecture and Anion Vacancy on BiTe@NPCNFs for Fast and Stable Potassium Ion Storage.

Large volume strain and slow kinetics are the main obstacles to the application of high-specific-capacity alloy-type metal tellurides in potassium-ion storage systems. Herein, BiTe nanocrystals with abundant Te-vacancies embedded in nitrogen-doped porous carbon nanofibers (BiTe@NPCNFs) are proposed to address these challenges. In particular, a hierarchical porous fiber structure can be achieved by the polyvinylpyrrolidone-etching method and is conducive to increasing the Te-vacancy concentration.

Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors.

Mid-pancreatectomy combined with end-to-end anastomosis is a surgical procedure used to treat benign pancreatic tumors. It involves removing the tumor from the middle section of the pancreas and connecting the proximal and distal ends through an anastomosis. The traditional surgical approach for resecting the middle segment of the pancreas involves closing the proximal pancreas and creating a Roux-en-Y anastomosis with the jejunum.

Efficient Polytelluride Anchoring for Ultralong-Life Potassium Storage: Combined Physical Barrier and Chemisorption in Nanogrid-in-Nanofiber.

Metal tellurides (MTes) are highly attractive as promising anodes for high-performance potassium-ion batteries. The capacity attenuation of most reported MTe anodes is attributed to their poor electrical conductivity and large volume variation. The evolution mechanisms, dissolution properties, and corresponding manipulation strategies of intermediates (K-polytellurides, K-pTe) are rarely mentioned.

LRP4-related signalling pathways and their regulatory role in neurological diseases.

The mechanism of action of low-density lipoprotein receptor related protein 4 (LRP4) is mediated largely via the Agrin-LRP4-MuSK signalling pathway in the nervous system. LRP4 contributes to the development of synapses in the peripheral nervous system (PNS). It interacts with signalling molecules such as the amyloid beta-protein precursor (APP) and the wingless type protein (Wnt).

Efficient-Lightweight YOLO: Improving Small Object Detection in YOLO for Aerial Images.

The most significant technical challenges of current aerial image object-detection tasks are the extremely low accuracy for detecting small objects that are densely distributed within a scene and the lack of semantic information. Moreover, existing detectors with large parameter scales are unsuitable for aerial image object-detection scenarios oriented toward low-end GPUs. To address this technical challenge, we propose efficient-lightweight You Only Look Once (EL-YOLO), an innovative model that overcomes the limitations of existing detectors and low-end GPU orientation.

The neutrophil-to-lymphocyte ratio and lactate dehydrogenase combined in predicting liver metastasis and prognosis of colorectal cancer.

Background: The neutrophil-to-lymphocyte ratio (NLR) and lactate dehydrogenase (LDH) level are inflammatory markers related to tumor growth and metabolism. This study investigated the value of preoperative NLR, LDH and the combination of NLR and LDH (NLR-LDH) for predicting colorectal cancer liver metastasis (CRLM) and tumor prognosis in the early stages of colorectal cancer (CRC).

Materials And Methods: Three hundred patients undergoing CRC resection were included.