The triglyceride-glucose index associated with reduced risk of liver metastasis in pancreatic cancer.

Background: The triglyceride-glucose (TyG) index has emerged as a reliable surrogate marker for insulin resistance and is associated with multiple malignancies. However, its role in pancreatic cancer liver metastasis (PCLM) remains unclear. This study aimed to investigate the relationship between TyG index and PCLM and evaluate its predictive value for PCLM.

Radiotherapy-induced TACC3 confers resistance of HCC to radiotherapy and enhances IL4-dependent immunosuppression to exacerbate hepatocarcinogenesis.

Radiotherapy plays an increasingly crucial role in the treatment of hepatocellular carcinoma (HCC). However, resistance to radiotherapy remains a significant obstacle to achieving optimal treatment outcomes. Our objective is to elucidate the mechanisms underlying radiotherapy resistance.

Risk factors, prognostic factors, and nomograms for liver metastasis in stage T-T colorectal cancer patients from a population-based study.

Liver metastasis(LM) is the primary cause of mortality in patients with colorectal cancer. The incidence of liver metastasis in patients with stage T-T colorectal cancer is uncommon, and there is limited research available. While nomograms have been increasingly utilized in oncology, there is a lack of studies focusing on the diagnosis and prognostic assessment of liver metastasis in patients with stage T-T colorectal cancer.

LncRNA HOXB-AS3 promotes proliferation, migration, and invasion of gallbladder cancer cells by activating the MEK/ERK pathway.

Background: LncRNA HOXB-AS3 are associated with tumor progression in several types of carcinomas, yet, its possibly biological role in gallbladder carcinoma(GBC) remains unclear. Therefore, this study aimed to investigate the biological function of HOXB-AS3 in GBC.

Methods: To know the potential function of HOXB-AS3 in gallbladder carcinoma, real-time polymerase chain reaction was used to detected the expression of HOXB-AS3 in gallbladder carcinoma cells.

Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors.

Mid-pancreatectomy combined with end-to-end anastomosis is a surgical procedure used to treat benign pancreatic tumors. It involves removing the tumor from the middle section of the pancreas and connecting the proximal and distal ends through an anastomosis. The traditional surgical approach for resecting the middle segment of the pancreas involves closing the proximal pancreas and creating a Roux-en-Y anastomosis with the jejunum.

Survival benefit of primary tumor resection for gastric cancer with liver metastasis: A propensity score-matched, population-based study.

Objectives: Gastric cancer with liver metastasis (GCLM) is highly aggressive and has a poor prognosis. This study aims to evaluate the survival benefit of primary tumor resection (PTR) for gastric cancer with liver metastasis.

Methods: Data on patients with GCLM was extracted from the Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2015.

suppresses the proliferation, migration, and invasion of gallbladder cancer cells by targeting and regulating the pathway.

Background: MicroRNA-messenger RNA (miRNA-mRNA) regulatory networks are essential factors that regulate tumor development and metastasis in various cancers including gallbladder carcinoma (GBC). Here, we identified the () axis in GBC by bioinformatics analysis and aimed to investigate its role and regulatory mechanism in the development and progression of GBC.

Methods: Bioinformatics analysis was used to construct a miRNA-mRNA regulatory network.