Analysis of regional characteristics in mortality trends of three chronic infectious diseases among the elderly in China, 2004-2021.

Background: HIV/AIDS, hepatitis B, and tuberculosis (TB) are chronic infectious diseases prioritized by the United Nations Sustainable Development Goals (SDGs) and China's "Healthy China Initiative (2019-2030)," posing persistent challenges to global and Chinese public health systems. This study analyzed mortality trends and regional/urban-rural disparities of these three diseases among Chinese elderly individuals aged 60 years and older from 2004 to 2021 to identify priority areas for targeted prevention strategies.

Methods: Data were sourced from the "China Cause-of-Death Surveillance Dataset (2004-2021)" published by the Chinese Center for Disease Control and Prevention.

Pulmonary Embolism in Children With Mycoplasma Pneumoniae Pneumonia: Assessment of Risk Factors and Current Prediction Criteria.

Purpose: Pulmonary embolism (PE) is recognized as a life-threatening complication of Mycoplasma pneumoniae pneumonia (MPP). We aimed to evaluate the risk factors of MPP with PE and examine the diagnostic accuracy of three adult-validated PE prediction criteria in children.

Methods: We retrospectively analyzed MPP patients who underwent computerized tomography pulmonary angiography (CTPA) due to suspicion of PE at the Children's Hospital of Nanjing Medical University from January 2019 to December 2023.

Overexpression of pectate lyase gene FvPLB leads to pollen abortion in Fragaria vesca.

The pectate lyase gene FvPLB has been implicated in the regulation of fruit softening in previous studies. We have now also found that abortions occurred in FvPLB overexpression lines. After overexpression of FvPLB, the cellulose content in the pollen grain and pollen tube wall was not affected, but the esterified and de-esterified pectin content in the pollen grain and pollen tube wall was significantly reduced, resulting in looser cell walls and deeper pollen grain deformation.

Individual cardiorespiratory fitness exercise prescription for older adults based on a back-propagation neural network.

Introduction: To explore and develop a backpropagation neural network-based model for predicting and generating exercise prescriptions for improving cardiorespiratory fitness in older adults.

Methods: The model is based on data from 68 screened studies. In addition, the model was validated with 64 older adults aged 60-79 years.

Trends in tuberculosis mortality among older adults in China, 2004-2021: a Joinpoint regression and age-period-cohort analysis.

Background: Tuberculosis (TB) remains a major public health problem in China and globally, particularly among older adults. This study aimed to examine secular trends in TB mortality among older adults in China and the net effects of age, period, and cohort.

Methods: Data from the National Disease Surveillance Points (DSPs) system were analyzed using Joinpoint regression to determine annual changes in TB mortality among individuals aged 60 years and older from 2004 to 2021.

Probiotics suppress LL37 generated rosacea-like skin inflammation by modulating the TLR2/MyD88/NF-κB signaling pathway.

Rosacea, a chronic inflammatory dermatological condition, is characterized by facial erythema and pustules. Recent investigations have delved into the interplay between the gut microbiota and rosacea pathogenesis, unveiling promising avenues for therapeutic intervention. In this study, we screened and isolated strains 23-006 and 23-008 from the feces of healthy volunteers and evaluated the intervention effects of probiotics on rosacea by constructing an LL37 induced rosacea-like mouse model.

Source-independent quantum secret sharing with entangled photon pair networks.

The large-scale deployment of quantum secret sharing (QSS) in quantum networks is currently challenging due to the requirements for the generation and distribution of multipartite entanglement states. Here we present an efficient source-independent QSS protocol utilizing entangled photon pairs in quantum networks. Through the post-matching method, which means the measurement events in the same basis are matched, the key rate is almost independent of the number of participants.

The Inhibitory Effect of Early Pregnancy Factor on Red Meat Neu5Gc-Mediated Antibody Production in CMAH Mice.

The meat derived from mammals such as cows, sheep, and pigs is commonly referred to as red meat. Recent studies have shown that consuming red meat can activate the immune system, produce antibodies, and subsequently develop into tumors and cancer. This is due to the presence of a potential carcinogenic compound in red meat called -ethanol neuraminic acid (Neu5Gc).

Nanoplasmonic biosensors for precision medicine.

Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry's need for low-cost, rapid and portable aspects, while offering multiplexing, high sensitivity and real-time detection. In this review, we describe the common detection schemes used based on localized plasmon resonance (LSPR) and highlight three sensing classes based on LSPR.

Nanodiamond-Enhanced Nanofiber Separators for High-Energy Lithium-Ion Batteries.

Current lithium-ion battery separators made from polyolefins such as polypropylene and polyethylene generally suffer from low porosity, low wettability, and slow ionic conductivity and tend to perform poorly against heat-triggering reactions that may cause potentially catastrophic issues, such as fire. To overcome these limitations, here we report that a porous composite membrane consisting of poly(vinylidene fluoride--hexafluoropropylene) nanofibers functionalized with nanodiamonds (NDs) can realize a thermally resistant, mechanically robust, and ionically conductive separator. We critically reveal the role of NDs in the polymer matrix of the membrane to improve the thermal, mechanical, crystalline, and electrochemical properties of the composites.

A rapid and inexpensive nucleic acid detection platform for Listeria monocytogenes based on the CRISPR/Cas12a system.

Listeria monocytogenes (LM) is an important foodborne pathogen that is associated with a high mortality rate. Currently, there is an urgent need for an inexpensive and rapid assay for the large-scale diagnosis and monitoring of LM. To meet these requirements, we designed a one-step, low-cost platform for the simultaneous amplification and detection of LM based on the CRISPR/Cas12a system with a micro-amplification (named Cas12a-MA).

Regular Tennis Exercise May Improve the Vascular Endothelial Function in Postmenopausal Women: The Influence of Hemodynamics.

Physical inactivity plays a role in the incidence of cardiovascular disease (CVD). Although the current guidelines for physical activity, such as the prescription of exercise, seek to combat CVD, attaining the recommended targets remains challenging. Tennis exercise has been proven to have a unique advantage in reducing the mortality of CVD, but little is known about the influence of playing tennis on impaired vascular endothelial function (VEF), which initiates CVD.

Effects of selenate and selenite on selenium accumulation and speciation in lettuce.

Lettuce is a common vegetable in hydroponic production. In this paper, a selenium (Se)-biofortification method was provided. The Se content, speciation, and the effects of different concentrations of selenate and selenite on lettuce growth and amino acids were investigated.

Ultra-Sensitive and Rapid Detection of Pathogenic Based on the CRISPR/Cas12a Nucleic Acid Identification Platform.

is a dangerous foodborne human pathogen that mainly causes gastroenteritis. Ideal methods for the detection of pathogens in food should be rapid, sensitive, specific, and cost effective. To this end, novel in vitro nucleic acid identification methods based on clustered, regularly interspaced short palindromic repeats (CRISPR)-associated protein (Cas) endonuclease have received increasing attention.

Electrolyte melt infiltration for scalable manufacturing of inorganic all-solid-state lithium-ion batteries.

All-solid-state lithium (Li) metal and lithium-ion batteries (ASSLBs) with inorganic solid-state electrolytes offer improved safety for electric vehicles and other applications. However, current inorganic ASSLB manufacturing technology suffers from high cost, excessive amounts of solid-state electrolyte and conductive additives, and low attainable volumetric energy density. Such a fabrication method involves separate fabrications of sintered ceramic solid-state electrolyte membranes and ASSLB electrodes, which are then carefully stacked and sintered together in a precisely controlled environment.

Hyperbranched molecules having multiple functional groups as effective corrosion inhibitors for Al alloys in aqueous NaCl.

Hyperbranched molecules are a kind of promising materials due to their unique structures. In this work, two hyperbranched molecules (GON and GOH) are used as effective inhibitors for Al alloys in NaCl solution. Their inhibitive performances are evaluated by electrochemical measurements and surface characterization.

Cycle stability of conversion-type iron fluoride lithium battery cathode at elevated temperatures in polymer electrolyte composites.

Metal fluoride conversion cathodes offer a pathway towards developing lower-cost Li-ion batteries. Unfortunately, such cathodes suffer from extremely poor performance at elevated temperatures, which may prevent their use in large-scale energy storage applications. Here we report that replacing commonly used organic electrolytes with solid polymer electrolytes may overcome this hurdle.

Finite momentum Cooper pairing in three-dimensional topological insulator Josephson junctions.

Unconventional superconductivity arising from the interplay between strong spin-orbit coupling and magnetism is an intensive area of research. One form of unconventional superconductivity arises when Cooper pairs subjected to a magnetic exchange coupling acquire a finite momentum. Here, we report on a signature of finite momentum Cooper pairing in the three-dimensional topological insulator BiSe.

Infiltrated Porous Polymer Sheets as Free-Standing Flexible Lithium-Sulfur Battery Electrodes.

Free-standing, high-capacity Li2 S electrodes with capacity loadings in the range from 1.5 to 3.8 mA h cm(-2) are produced by using infiltration of active materials into porous carbonized biomass sheets.