Sensitivity analysis of PM and O co-pollution in Beijing based on GRAPES-CUACE adjoint model.

In recent years, incidents of simultaneous exceedance of PM and O concentrations, termed PM and O co-pollution events, have frequently occurred in China. This study conducted atmospheric circulation analysis on two typical co-pollution events in Beijing, occurring from July 22 to July 28, 2019, and from April 25 to May 2, 2020. These events were categorized into pre-trough southerly airflow type (Type 1) and post-trough northwest flow type (Type 2).

Assessing the impacts of climate anomalies on plague risk in China during 1754-1949.

Plague, a disease influenced by climatic and social factors, has historically caused devastating disasters in China. However, limited data availability has hindered our understanding of the relationship between climate, social conditions, and plague. Here we address a critical data gap by collecting and digitizing county-level plague grade data from China during 1754-1949 together with socio-climatic factors.

Heat exposure assessment based on high-resolution spatio-temporal data of population dynamics and temperature variations.

Urban heat waves pose a significant risk to the health and safety of city dwellers, with urbanization potentially amplifying the health impact of extreme heat. Accurate assessments of population heat exposure hinge on the interplay between temperature, population spatial dynamics, and the epidemiological effects of temperature on health. Yet, many past studies have over-simplified the matter by assuming static populations, leading to substantial inaccuracies in heat exposure assessments.

Effects of pollen concentration on allergic rhinitis in children: A retrospective study from Beijing, a Chinese megacity.

With global climate change and rapid urbanization, the prevalence of allergic diseases caused by pollen is rising dramatically worldwide with unprecedented complexity and severity, especially for children in mega-cities. However, because of the lack of long time-series pollen concentrations data, the accurate evaluation of the impact of pollen on allergic rhinitis (AR) was scarce in the Chinese metropolis. A generalized additive model was used to assess the effect of pollen concentration on pediatric AR outpatient visits in Beijing from 2014 to 2019.

Influence of Urbanization on the Spatial Distribution of Associations Between Air Pollution and Mortality in Beijing, China.

This study investigated the influence of urbanization on the intra-city spatial distribution of associations between air pollution and mortality in Beijing, China. First, we utilized the generalized additive model to establish the exposure-response associations of PM, O, with nonaccidental and cardiorespiratory mortality between urban and suburban areas. Second, we assessed district-specific air pollution-related mortality and analyzed how these associations were affected by the degree of urbanization.

Upper respiratory tract microbiota is associated with small airway function and asthma severity.

Background: Characteristics of airway microbiota might influence asthma status or asthma phenotype. Identifying the airway microbiome can help to investigate its role in the development of asthma phenotypes or small airway function.

Methods: Bacterial microbiota profiles were analyzed in induced sputum from 31 asthma patients and 12 healthy individuals from Beijing, China.

Identification of Health Effects of Complex Air Pollution in China.

After the Chinese government introduced a series of policies to strengthen the control of air pollution, the concentration of particulate matter has decreased, but the concentration of ozone has increased, and the problem of complex air pollution still exists, posing a serious threat to public health. Therefore, disentangling the health effect of multi-pollutants has been a long-discussed challenge in China. To evaluate the adverse effects of complex air pollution, a generalized additive model was used to assess the health risks of different pollution types in eight metropolises in different climates in China from 2013 to 2016.

Acute effects of black carbon on mortality in nine megacities of China, 2008-2016: a time-stratified case-crossover study.

Black carbon (BC) may have more adverse effects on human health than other constituents of PM. The daily mean concentrations of BC in China are much higher than those in developed countries and are estimated to account for more than a quarter of global anthropogenic BC emissions. However, reports on the health effects of BC in China have been limited.

Assessment of black carbon exposure level and health economic loss in China.

Based on the geographic information system (GIS) software and the application of the black carbon (BC) and fine particulate matter ([Formula: see text]) ratio method, this paper analyzed and calculated the national BC distribution from 2015 to 2017 and evaluated the national human exposure to BC. The results showed that from 2015 to 2017, 2/3 of the national land area and nearly half of the population were exposed to 1-3 [Formula: see text], and the area and population exposed to a concentration less than 2 [Formula: see text] increased yearly, while the area and population exposed to a concentration higher than 9 [Formula: see text] decreased yearly. The estimated economic loss showed that 77.

Development of GRAPES-CUACE adjoint model version 2.0 and its application in sensitivity analysis of ozone pollution in north China.

We presented the development of the gaseous chemistry adjoint module of the meteorological-chemical model system GRAPES-CUACE (Global/Regional Assimilation and PrEdiction System coupled with CMA Unified Atmospheric Chemistry Environmental Forecasting System) on the basis of the previously constructed aerosol adjoint module. The latest version of the GRAPES-CUACE adjoint model mainly includes the adjoint of the physical and chemical processes, the adjoint of the transport processes, and the adjoint of interface programs, of both gas and aerosol. The adjoint implementation was validated for the full model, and adjoint results showed good agreement with brute force sensitivities.

Ultrafine black carbon caused mitochondrial oxidative stress, mitochondrial dysfunction and mitophagy in SH-SY5Y cells.

Exposure to ambient ultrafine black carbon (uBC, with aerodynamic diameter less than 100 nm) is associated with many neurodegenerative diseases. Oxidative stress is the predominantly reported neurotoxic effects caused by uBC exposure. Mitochondrion is responsible for production of majority of ROS in cells and mitochondrial dysfunction is closely related to adverse nervous outcomes.

Evolution of boundary layer ozone in Shijiazhuang, a suburban site on the North China Plain.

The structure of the boundary layer affects the evolution of ozone (O), and research into this structure will provide important insights for understanding photochemical pollution. In this study, we conducted a one-month observation (from June 15 to July 14, 2016) of the boundary layer meteorological factors as well as O and its precursors in Luancheng County, Shijiazhuang (37°53'N, 114°38'E). Our research showed that photochemical pollution in Shijiazhuang is serious, and the mean hourly maximum and mean 8-hr maximum O concentrations are 97.

Assessment of resident's exposure level and health economic costs of PM10 in Beijing from 2008 to 2012.

Epidemiological studies have asserted a negative association between atmospheric particulates and human health, especially particulate matter (PM10), which can cause a noticeable damage to human health. In recent years, PM10 has become the primary pollutant in major cities in China. It is crucial to evaluate the health impacts of PM10 to make pollution control policies and protect public health.

Association between PM10 and respiratory hospital admissions in different seasons in heavily polluted Lanzhou City.

Exposure-response relationship between particulate matter less than 10 μm in diameter (PM10) and human health in different seasons from 2001 to 2005 was examined based on hospital admissions data of respiratory system diseases from four major hospitals in Lanzhou, China. To quantify associations of respiratory system diseases with multiple air pollutants and meteorological conditions, a semiparametric generalized additive model was used in the authors' study by implementing daily ambient sulfur dioxide, nitrogen dioxide, and PM10 data collected from the Lanzhou Environmental Monitoring Station and daily meteorological data from Lanzhou Meteorological Bureau. Results showed that daily averaged PM10 increased per interquartile range the hospital admissions number of respiratory diseases by 3.

Assessment of population exposure to PM10 for respiratory disease in Lanzhou (China) and its health-related economic costs based on GIS.

Background: Evaluation of the adverse health effects of PM10 pollution (particulate matter less than 10 microns in diameter) is very important for protecting human health and establishing pollution control policy. Population exposure estimation is the first step in formulating exposure data for quantitative assessment of harmful PM10 pollution.

Methods: In this paper, we estimate PM10 concentration using a spatial interpolation method on a grid with a spatial resolution 0.

Emission inventory evaluation using observations of regional atmospheric background stations of China.

Any accurate simulation of regional air quality by numerical models entails accurate and up-to-date emissions data for that region. The INTEX-B2006 (I06), one of the newest emission inventories recently popularly used in China and East Asia, has been assessed using the Community Multiscale Air Quality model and observations from regional atmospheric background stations of China. Comparisons of the model results with the observations for the species SO2, NO2, O3 and CO from the three regional atmospheric background stations of Shangdianzi, Longfengshan and Linan show that the model can basically capture the temporal characteristics of observations such as the monthly, seasonal and diurnal variance trends.

An assessment of China's PM10-related health economic losses in 2009.

Using GIS software and based on exposure-response functions, this paper estimated the health-related economic losses that China suffered in 2009 due to the presence of particulate matter (PM(10)). The results show that China suffered a health-related economic loss due to PM(10) of US$ 106.5 billion, or 2.

Association between dust weather and number of admissions for patients with respiratory diseases in spring in Lanzhou.

Controlling the confounding factors on respiratory hospitalizations such as long-term trend, meteorological factor, atmospheric pollution, and calendar effect, the research is designed to study the effect of sand-dust weather on respiratory diseases from 2001 to 2005 in Lanzhou City on the basis of the semi-parametric generalized additive model (GAM). The results indicate that there is an association between sand-dust weather and the increase in respiratory hospitalizations, and with lagging effect. There are gender and age differences in the effect of sand-dust weather on health, on male severer than on female (RR value being 1.