Exploring the complexity of methylphosphonic acid sorption on marine sediments: The influence of organic matter and environmental factors.

This study investigated the sorption characteristics of methylphosphonic acid (MPn) on marine sediments, focusing on the effects of sediment composition and environmental factors. The results indicated that MPn showed good stability on sediment samples and physical process was the main fraction for MPn sorption. Light fraction organic matter (LFOM) significantly enhanced the sorption ability of the sediments.

Bioartificial liver: Where lies the path ahead-A review.

Despite its proven effectiveness in treating liver failure, liver transplantation is often impractical due to its high surgical risks involved and the limited availability of donor organs. Blood purification technologies used in non-bioartificial liver (NBAL) systems have improved clinical cure rates, but they do not substitute for the complex biosynthesis, detoxification, metabolism, and biological transformation roles of the liver. To overcome these challenges brought by NBAL systems, bioartificial liver (BAL) systems have been developed with repeated optimization of both hepatocyte sources and bioreactors to emulate a "fully functional liver".

Structures and Relative Stabilities of An(IV)-DOTA Complexes from First-Principles and Ab Initio Calculations.

The structures and relative stabilities of complexes of the DOTA ligand with tetravalent actinide ions An (An = Th, Pa, U, Np, Pu) in the gas phase and aqueous solution have been studied by relativistic An pseudopotentials combined with gradient-corrected density functional theory BP86 as well as Møller-Plesset second-order perturbation theory MP2 and the approximate coupled cluster singles and doubles model CC2. The complexes are found to become more stable along the actinide series, and the squared antiprismatic conformation is found to be lower in energy than the twisted squared antiprismatic one. Covalent actinide-ligand bonding contributions are analyzed and found to arise mainly for the actinide-oxygen bonds, and to a lesser extent for the actinide-nitrogen bonds.

Spectral characteristics of organic matter from algae and its complexation with copper: a case study of Ulva prolifera.

The changes in dissolved organic matter (DOM) during algal decay play a crucial role in the biochemical processes in nearshore ecosystems. The decay processes of Ulva prolifera under dark and light conditions were simulated in laboratory to investigate the characteristics of the DOM released during its settlement. The spectral characteristics of Ulva prolifera-DOM were analyzed using ultraviolet-visible spectra (UV-Vis) and fluorescence excitation-emission matrix spectroscopy combined with parallel factor analysis (EEMs-PARAFAC), and the copper complexation characteristics were evaluated by anodic stripping voltammetry (ASV).

Transcriptome and detoxification enzyme-related gene analysis of the Cydia pomonella response to walnut husks.

Walnut husks, as an agricultural by-product, have various applications in industries such as food, agriculture, and medicine. However, few studies have examined the effects of walnut husks on the growth, development, and RNA levels of Cydia pomonella larvae. This study preliminarily elucidated the detoxification mechanism of C.

Unveiling Nonadiabatic Pathways in Small Molecule Activation: Dinuclear Uranium-Mediated H and N Bond Cleavage.

Nonadiabatic effects have been extensively studied in photoexcited processes, but their role in thermal process so far has neither been thoroughly studied nor appreciated, despite their significance. In this work, H and N activation mediated by a diuranium complex was studied from a nonadiabatic perspective using multi-configurational ab initio calculations combined with density functional theory. Stepwise electron transfer during the reaction enhances degeneracy between electronic states, enabling state-to-state transitions, i.

Experimental degradation of Ulva prolifera in sand sediments: Implications for dissolved carbon and alkalinity export from green-tide macroalgae buried in sandy intertidal zones.

The degradation of massive Ulva prolifera (U. prolifera), generated during blooms of the macroalgae (i.e.

Safety and efficacy of intravesical instillation of botulinum toxin-A in the treatment of interstitial cystitis/bladder pain syndrome and overactive bladder: a systematic review and meta-analysis.

Background: The effectiveness and safety of the instillation of botulinum toxin A (BTX-A) remain subjects of controversy. The meta-analysis was performed to assess the efficacy and safety of a novel intravesical instillation of BTX-A for managing overactive bladder (OAB) or interstitial cystitis/bladder pain syndrome (IC/BPS).

Method: The randomized controlled trials were retrieved from PubMed, EMBASE, and the Cochrane Library databases up to 29 January 2024.

Developing an aurone-based colorimetric fluorescent probe for fast cysteine sensing in foods, test strips and biological imaging.

Cysteine (Cys) is integral to both industrial applications and biological processes. In this study, a novel colorimetric fluorescent sensor APA, defined by its intramolecular charge transfer (ICT) properties, was optimized to effectively discriminate Cys from other structurally similar compounds such as homocysteine (Hcy) and glutathione (GSH). We present the aurone-incorporated fluorescent sensor APA, which features a 4-dimethylaminocinnamaldehyde group conjugated to the aurone scaffold and facilitates selective detection of Cys with a limit of detection (LOD) of 25.

Effect of Crosslinking Temperature on the Insulation Performance of XLPE Secondary Crosslinking Insulation Interface Layer.

To investigate the impact of temperature variations during the secondary crosslinking of cross-linked polyethylene (XLPE) on the insulation performance of the interface layer, commercial XLPE cable pellets were subjected to flat hot pressing at 140 °C, 160 °C, 180 °C, and 200 °C. XLPE insulation interface layers were prepared at different secondary crosslinking temperatures. The samples were characterized by gel content, differential scanning calorimetry (DSC), thermal elongation test, power frequency breakdown voltage, and scanning electron microscope (SEM).

Discovery of Novel Inhibitors Targeting Fungal Chitin Deacetylase via Virtual Screening for Plant Disease Control.

Fungal chitin deacetylase (CDA) plays a crucial role in pathogen-plant interactions, which is regarded as an innovative and promising target for fungicides. In this study, a pharmacophore-based virtual screening strategy was employed to identify compounds and as potent inhibitors against f. sp.

Effectiveness and clinical impact of using deep learning for first-trimester fetal ultrasound image quality auditing.

Background: Regular auditing of ultrasound images is required to maintain quality; however, manual auditing is time-consuming and can be inconsistent. We therefore aimed to develop and validate an artificial intelligence-based image quality audit (AI-IQA) system to audit images from the four key planes used in first-trimester scanning.

Methods: The AI-IQA system was developed based on the YOLOv7 structure detection network and a multi-branch image quality regression network using a large multicenter internal dataset.

TOPIC: A Parallel Association Paradigm for Multi-Object Tracking under Complex Motions and Diverse Scenes.

Video data and algorithms have been driving advances in multi-object tracking (MOT). While existing MOT datasets focus on occlusion and appearance similarity, complex motion patterns are widespread yet overlooked. To address this issue, we introduce a new dataset called BEE24 to highlight complex motions.

Walnut husk transcriptome dataset of codling moth () infestation at different times.

Walnuts, along with almonds, cashews, and hazelnuts, are renowned as the world's "four famous nuts," with walnuts being the foremost among them. Walnut fruit is rich in nutrients, including proteins, fats, polyphenols, sugars, phospholipids, melatonin, sterols, flavonoids, iron, zinc, manganese, and other trace elements, as well as dietary fiber. However, the codling moth poses a significant threat to walnut fruits as a major pest.

Characterization of 4-coumarate CoA ligase (4CL) gene family and functional study of Sm4CL2/3/7/9 in Salvia miltiorrhiza.

The 4-coumarate CoA ligase (4CL, EC6.2.1.

A Novel Platform Featuring Nanomagnetic Ligand Fishing Based on Fixed-Orientation Immobilized Magnetic Beads for Screening Potential Cyclooxygenase-2 Inhibitors from Leaves.

A novel screening platform based on an FeO@C@PDA-Ni@COX-2 ligand fishing combination with high-performance liquid chromatography-mass spectrometry was first designed, synthesized, and employed to screen and identify COX-2 inhibitors from leaves. The obtained magnetic nanoparticles exhibit outstanding preconcentration ability that allows for controlling the enzyme orientation to avoid enzyme active site blocking, conformational changes, or denaturing during immobilization. The as-prepared FeO@C@PDA-Ni@COX-2 composite was carefully characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectrometry (FT-IR), Xray powder diffraction (XRD), thermal gravimetric analyzer (TGA), vibrating sample magnetometer (VSM), and Zeta potential analysis.

Fatty Acid Metabolism Disruptions: A Subtle yet Critical Factor in Adverse Pregnancy Outcomes.

The establishment and maintenance of pregnancy encompass a series of complex and high-energy-consuming physiological processes, resulting in a significant energy demand. Fatty acids, one of the most essential nutrients, play a crucial role in energy supply via oxidation and perform critical biological functions such as anti-inflammatory and anti-oxidant effects, which substantially impact human health. Disordered fatty acid metabolism can cause anomalies in fetal growth and development, as well as a range of pregnancy problems, which can influence the health of both the mother and the fetus.

Transcription factors CpSPL5 and CpSPL8 negatively regulate salt tolerance in Codonopsis pilosula by inhibiting SOS pathway.

Environmental stresses such as salt and drought severely affect plant growth and development. SQUAMOSA-promoter binding protein-like (SPL) transcription factors (TFs) play critical roles in the regulation of diverse processes; however, reports describing the SPL regulation of plant responses to abiotic stress are relatively few. In this study, two stress-responsive TFs from Codonopsis pilosula (CpSPL5 and CpSPL8) are reported, which confer salt stress sensitivity.

Risk assessment of careHPV testing for the detection of cervical precancerous lesions: 5-year follow-up of a screening program in China.

Background: CareHPV is a highly promising screening HPV assay that functions as a simplified and rapid point-of-care test, making it particularly well-suited for low-resource areas. It exhibits high sensitivity for detecting cervical precancerous lesions in cross-sectional study design. However, there is still limited evidence on the long-term protection of careHPV testing in the practical setting.

Effects of drought stress on the secondary metabolism of Scutellaria baicalensis Georgi and the function of SbWRKY34 in drought resistance.

The pharmacological properties of the dried root of Scutellaria baicalensis Georgi, a Chinese medicinal herb, include antioxidant, antibacterial, and antiviral effects. In S. baicalensis quality assessment, concentrations of baicalin, wogonoside, baicalein, and wogonin in the root are crucial.

SmJAZ1/8 inhibits the stimulation of SmbHLH59, which limits the accumulation of salvianolic acids and tanshinones in Salvia miltiorrhiza.

Salvia miltiorrhiza is a model medicinal plant that is typically used to treat cardiovascular and cerebrovascular diseases. The primary active medicinal ingredients of S. miltiorrhiza are salvianolic acids and tanshinones.

microRNA858 represses the transcription factor gene SbMYB47 and regulates flavonoid biosynthesis in Scutellaria baicalensis.

MicroRNAs (miRNAs) are noncoding endogenous single-stranded RNAs that regulate target gene expression by reducing their transcription and translation. Several miRNAs in plants function in secondary metabolism. The dried root of Scutellaria baicalensis Georgi is a traditional Chinese medicine that contains flavonoids (baicalin, wogonoside, and baicalein) as its main active ingredients.

Analysis of rosmarinic acid synthase (RAS) gene family and functional study of SmRAS1/2/4 in Salvia miltiorrhiza.

Rosmarinic acid synthase is an essential enzyme involved in the biosynthesis of rosmarinic acid (RA), which facilitates the coupling of phenylpropanoid and tyrosine-derived pathway products. Our study identified six SmRAS genes in Salvia miltiorrhiza, with SmRAS1 being the only one functionally characterized to date. Real-time quantitative PCR was employed to analyze the expression profiles of the SmRAS gene family, revealing that SmRAS1/2/4 are predominantly expressed in the roots, which are the medicinal components of S.

Assessment of suitable region of (Lour.) Merr. under different climatic conditions in China by the MaxEnt model and HPLC analysis.

is a member of the Asparagaceae family whose medicinal part is the dried root tuber. The distribution of and its secondary metabolites are closely associated with environmental factors, such as climate and soil properties. By establishing and optimizing a maximum entropy model, we analyzed and predicted the distribution pattern and migration direction of suitable habitats for and determined the main environmental factors affecting the accumulation of secondary metabolites.