A skin-interfaced three-dimensional closed-loop sensing and therapeutic electronic wound bandage.

Chronic wound healing is a complex and long-standing problem, that has been a major and critical clinical concern around the world for years. Recent advances in digital wound dressings open new possibilities for solving the problem. Here, we report a battery-free, fully permeable, skin-adhesive, stretchable electronic wound bandage (iSAFE) for intelligent wound management.

Risk Prediction Model for Elderly Differentiated Thyroid Cancer Based on Combined Sleep Quality Assessment and Multimodal Ultrasound.

Objective: To explore the differential diagnosis for benign and malignant thyroid nodules and the diagnostic value of sleep quality, to construct and validate a risk prediction model, providing the basis for clinical treatment decision for elderly thyroid cancer.

Methods: Clinical data, Pittsburgh Sleep Quality Index (PSQI), and multimodal ultrasound were collected from elderly patients undergoing fine needle aspiration biopsy or thyroid surgery in our department of endocrinology and general surgery. Postoperative pathological results served as the gold standard, binary logistic regression identified significant risk factors, and the receiver-operating characteristic (ROC) curves were plotted to construct and validate the prediction model.

Green, Safe, Durable, Printed Fabric Hygroelectric Generators for Wearable Systems.

Hygroelectric generators, converting energy from moisture into electricity, have attracted great interest due to sustainable and ubiquitous moisture in the environment. However, it is absolutely necessary to replace the fragile and noxious materials reported previously in the hygroelectric generators before real applications for wearables. Herein, a green hygroelectric generator with a high current density is designed for the first time by printing functional materials that are abundant, safe to humans and environments.

Wearable Fluidic Fabric with Excellent Heat Transfer Performance for Sports Recovery.

Rapid temperature contrast hydrotherapy by water immersion has been utilized by athletes for effective sports recovery. However, its application at some training or competition venues is limited by high water consumption, bucky size, personal hygiene, and inconvenience. Here, a novel portable system equipped with highly effective, lightweight, and hygienic wearable fluidic fabric device is reported, that replaces direct water immersion.

Performance Enhancement by Integrating the Ionic Thermoelectric Generator with a Photovoltaic Cell.

The global solar market is booming with a rapid growth in installed integrated devices, while photovoltaic (PV) systems are suffering from waste heat, which causes the decline of the photovoltaic conversion efficiency (PCE). This study presents the seamless integration of the ionic thermoelectric generator (iTEG) layer with traditional PV modules, facilitating the exploitation of waste heat and augmenting the overall power output. Experimental results validate the effectiveness of the iTEG, demonstrating substantial power generation and a consistent energy output.

MIMO-Uformer: A Transformer-Based Image Deblurring Network for Vehicle Surveillance Scenarios.

Motion blur is a common problem in the field of surveillance scenarios, and it obstructs the acquisition of valuable information. Thanks to the success of deep learning, a sequence of CNN-based architecture has been designed for image deblurring and has made great progress. As another type of neural network, transformers have exhibited powerful deep representation learning and impressive performance based on high-level vision tasks.

Mid-term effect of customized graduated elastic compression stockings for managing occupational edema: A randomized controlled trial.

Introduction: This study compared the effectiveness of customized graduated elastic compression stockings (c-GECS) based on individual lower-leg parameter models with standard graduated elastic compression stockings (s-GECS) in patients with occupational edema (OE).

Methods: A single-blind, randomized controlled trial was conducted with 70 patients with OE, randomly assigned to the c-GECS or s-GECS group. Follow-up assessments were performed at 1 and 3 months.

Integrated Wearable System for Monitoring Skeletal Muscle Force of Lower Extremities.

Continuous monitoring of lower extremity muscles is necessary, as the muscles support many human daily activities, such as maintaining balance, standing, walking, running, and jumping. However, conventional electromyography and physiological cross-sectional area methods inherently encounter obstacles when acquiring precise and real-time data pertaining to human bodies, with a notable lack of consideration for user comfort. Benefitting from the fast development of various fabric-based sensors, this paper addresses these current issues by designing an integrated smart compression stocking system, which includes compression garments, fabric-embedded capacitive pressure sensors, an edge control unit, a user mobile application, and cloud backend.

Brain-Inspired Image Perceptual Quality Assessment Based on EEG: A QoE Perspective.

Human-oriented image communication should take the quality of experience (QoE) as an optimization goal, which requires effective image perceptual quality metrics. However, traditional user-based assessment metrics are limited by the deviation caused by human high-level cognitive activities. To tackle this issue, in this paper, we construct a brain response-based image perceptual quality metric and develop a brain-inspired network to assess the image perceptual quality based on it.

Green moisture-electric generator based on supramolecular hydrogel with tens of milliamp electricity toward practical applications.

Moisture-electric generators (MEGs) has emerged as promising green technology to achieve carbon neutrality in next-generation energy suppliers, especially combined with ecofriendly materials. Hitherto, challenges remain for MEGs as direct power source in practical applications due to low and intermittent electric output. Here we design a green MEG with high direct-current electricity by introducing polyvinyl alcohol-sodium alginate-based supramolecular hydrogel as active material.

A multimodal physiological dataset for driving behaviour analysis.

Physiological signal monitoring and driver behavior analysis have gained increasing attention in both fundamental research and applied research. This study involved the analysis of driving behavior using multimodal physiological data collected from 35 participants. The data included 59-channel EEG, single-channel ECG, 4-channel EMG, single-channel GSR, and eye movement data obtained via a six-degree-of-freedom driving simulator.

TBEEG: A Two-Branch Manifold Domain Enhanced Transformer Algorithm for Learning EEG Decoding.

The electroencephalogram-based (EEG) brain-computer interface (BCI) has garnered significant attention in recent research. However, the practicality of EEG remains constrained by the lack of efficient EEG decoding technology. The challenge lies in effectively translating intricate EEG into meaningful, generalizable information.

In Vitro Detection of Lactate and Uric Acid Based on Adaptive Graphene Oxide Membranes.

In vitro detection of small molecules in the human circulatory system contributes a lot to prompt personalized healthcare and early disease diagnose. The precise detection requires to select target molecules for real-time noninvasive identifications, which remains a challenge derived from the lack of both molecule-sieving techniques and rapid detection tools. Herein, positively charged polymer chains into graphene oxide membranes are seeded to tune their interlayer spacing precisely and persistently within a range of 8.

The value of ultrasensitive C-reactive protein and homocysteine levels in predicting the diagnosis and functional prognostic assessment of cerebral infarction in the elderly.

Objective: To evaluate the diagnostic value of ultrasensitive C-reactive protein (hs-CRP) and homocysteine (Hcy) for cerebral infarction.

Methods: 260 elderly patients with cerebral infarction were recruited and assigned to the stroke group, and 60 healthy elderly were identified as controls and included in the normal group. Serum samples of all subjects were collected at the time of admission for the determination of hs-CRP and Hcy levels.

A randomized controlled trial of standard vs customized graduated elastic compression stockings in patients with chronic venous disease.

Objective: This study aimed to compare the efficacy of customized graduated elastic compression stockings (c-GECSs) based on lower leg parameter models with standard GECSs (s-GECSs) in patients with chronic venous disease (CVD).

Methods: In this randomized, single-blind, controlled trial, 79 patients with stage C2 or C3 CVD were assigned to one of two groups: c-GECSs or s-GECSs. The primary outcome was change to Venous Insufficiency Epidemiological and Economic Study Quality of Life (VEINES-QOL) scores at months 1, 3, and 6 as compared with baseline.

Technology Roadmap for Flexible Sensors.

Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited.

Asymmetric strategy for enhanced performance of flexible electroadhesive clutch.

Flexible electroadhesive clutches with high shear stress and fast response working at low voltage are much desired in wearable electronics and robotic systems. Dielectric materials with opposite charge characteristics could maximize the clutch performance by taking advantages of the boosted electroadhesion between the two contact pads in an asymmetrically structured clutch. In this paper, asymmetrically structured electroadhesive clutches are proposed and reported for the first time.

Evaluating and Modeling the Degradation of PLA/PHB Fabrics in Marine Water.

Developing degradable bio-plastics has been considered feasible to lessen marine plastic pollution. However, unanimity is still elusive regarding the actual degradability of bio-plastics such as polylactide (PLA) and poly(hydroxybutyrate) (PHB). Thus, herein, we studied the degradability of fabrics made from PLA/PHB blends in marine seawater.

Fast NURBS-based parametric modeling of human calves with high-accuracy for personalized design of graduated compression stockings.

Background And Objectives: Accurate human body models are increasingly demanded by high-quality human-centered ergonomic applications, especially the design and manufacturing of compressive functional apparels. However, existing parametric models in related works are not capable to accurately describe detailed local shape features of human.

Methods: In this work, a high-accuracy parametric modeling approach for human limb was proposed.

Gut microbiota is correlated with gastrointestinal adverse events of metformin in patients with type 2 diabetes.

Aim: Gastrointestinal discomfort is the most common adverse event in metformin treatment for type 2 diabetes. The mechanism of action of metformin is associated with gut microbiota. However, the gut microbial community structure related to metformin-induced gastrointestinal adverse events remains unclear.

Silencing FOXP2 reverses vemurafenib resistance in BRAF mutant papillary thyroid cancer and melanoma cells.

Background: Vemurafenib (VEM) is a commonly used inhibitor of papillary thyroid cancer (PTC) and melanoma with the BRAF mutation; however, acquired resistance is unavoidable. The present study aimed to identify a potential target to reverse resistance.

Materials And Methods: A VEM-resistant PTC cell line (B-CPAP/VR) was established by gradually increasing the drug concentration, and a VEM-resistant BRAF melanoma cell line (A375/VR) was also established.

Synthesis of Polylactic Acid Oligomers for Broad-Spectrum Antimicrobials.

Infectious microbial diseases are a major public health hazard, calling for more innovative antimicrobials. Herein, polylactic acid (PLA) oligomers have been explored and reported as a bio-safe and eco-friendly functional antimicrobial agent against pathogens, such as viruses (H1N1, H3N2, and SARS-CoV-2), bacteria (E. coli, S.

Confirmation of the Absence of Somogyi Effect in Patients with Type 2 Diabetes by Retrospective Continuous Glucose Monitoring Systems.

Background: The Somogyi effect is defined as fasting hyperglycemia secondary to nocturnal hypoglycemia. In past decades, this effect proved to be rare or absent. However, many endocrinologists still believe in this phenomenon in clinical practice.

Novel oxymagnesite/green rust nanohybrids for selective removal and slow release of phosphate in water.

The new paradigm in wastewater treatment demands to change traditional pollutants removal into resource recovery, especially for non-renewable P resources, effectively recovering phosphate from wastewater and reutilizing it as a nutrient is crucial to P sustainable utilization and P-related pollution control. The nanomaterial-based adsorption technology for P recovery from wastewater is becoming a research hotspot due to its high efficiency and selectivity. Herein, to recover aqueous phosphate, we developed novel oxymagnesite/green rust (OMGR) nanohybrids by a one-pot hydrothermal method.