An intelligent stochastic optimization approach for air cargo order allocation under carbon emission constraints.

In air cargo transportation, effective order allocation is crucial for improving the efficiency of business operations and reducing environmental impact. In this paper, we study a high-dimensional stochastic order allocation problem that assigns uncertain orders to different types of aircraft for transportation. Considering the carbon emission and the uncertainty of customer order arrivals in the actual transportation environment, a stochastic optimization model considering the cost of carbon emission is established with the objective of maximizing the expected profit from order transportation.

An improved adaptive variable neighborhood search algorithm for stochastic order allocation problem.

In practical supply chain operations, efficient order allocation significantly enhances the overall efficiency of the supply chain. Real production environments are plagued by numerous uncertainties, such as unpredictable customer orders, which greatly amplify the complexity of solving practical allocation problems. This study focuses on the problem of allocating orders to parallel machines with varying efficiencies under uncertain and high-dimensional conditions.

Notes on the genus (Lepidoptera, Zygaenidae) with description of a new species from China.

The genus Efetov & Tarmann, 1995 includes six species occurring in southwest China and Indian Sikkim. In the present paper, Li & He, , the seventh species of the genus encountered at the foot of Galongla Snow Mountain, southeast Xizang of China is described. Habitus of the adult and genitalia of the new species are illustrated, and a checklist and a key of all species are provided.

Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer.

Background: Reactivate the T cell immunity by PD-1/PD-L1 checkpoint blockade is widely used in non-small cell lung cancer (NSCLC) patients, while the post-translational modification of Programmed death ligand-1 (PD-L1) is commonly existed in various cancer cells, thus increases the complexity and difficulty in therapy development. Ginsenoside Rg3 is an active component of traditional Chinese herb Ginseng with multiple pharmacological effects including immune regulation. However, the effect on the glycosylation of PD-L1 is unknown.

Sensorimotor Processing in Elite and Sub-Elite Adolescent Sprinters during Sprint Starts: An Electrophysiological Study.

Most studies on sprint performance have focused on kinematics and kinetics of the musculoskeletal system for adults, with little research on the central sensorimotor transmission and processes, especially for adolescent sprinters. This study aimed to determine whether differences in the integrity of the central auditory system and audiomotor transmissions between the elite and sub-elite adolescent sprinters may affect their performance in the 100 m time. Twenty-nine adolescent junior high school students, including elite national-class and sub-elite regional-class athletes, were assessed.

Stereochemical Control of Redox Co/Co-Cages with Switchable Cotton Effects Based on Labile-Static States.

The structural dynamics of artificial assemblies, in aspects such as molecular recognition and structural transformation, provide us with a blueprint to achieve bioinspired applications. Here, we describe the assembly of redox-switchable chiral metal-organic cages Λ/Δ-[Pd(CoL)] and Λ/Δ-[Pd(CoL)]. These isomeric cages demonstrate an on-off chirality logic gate controlled by their chemical and stereostructural dynamics tunable through redox transitions between the labile Co-state and static Co-state with a distinct Cotton effect.

Taxonomic study on the genus Verhoeff, 1930 (Isopoda, Agnaridae) from China: morphological and phylogenetic analyses.

A combination of morphological traits and DNA data (COI and 28S rRNA partial sequences) was used to study the genus Verhoeff, 1930 from China. Four new species are described: Jiang, Li & Huang, , Jiang, Li & Huang, , Jiang, Li & Huang, , and Jiang, Li & Huang, Following an in-depth examination of the species, (Arcangeli, 1927), (from ) is proposed, and Yang & An, 2021, . is synonymized with (Arcangeli, 1927).

First record of the subgenus Hemilepistus (Desertellio) (Isopoda, Agnaridae) from China.

The subgenus Hemilepistus (Desertellio) Verhoeff, 1930 is reported from China for the first time. A new species of the subgenus, H. (D.

A Two-Step Fluorescence-Resonance Energy Transfer System Constructed by Platinum(II) Metallacycle Based Molecular Recognition.

Considerable progress in the construction of efficient fluorescence-resonance energy transfer (FRET) systems has promoted the development of artificial energy transfer materials. However, despite recent advances, the exploration of efficient and easy strategies to fabricate novel supramolecular systems with FRET activities is still a challenge. Here, we report that a two-step FRET system was successfully achieved, driven by platinum metallacycle based host-guest interactions.

Integrative taxonomy on the rare sky-island Ligidium species from southwest China (Isopoda, Oniscidea, Ligiidae).

Background: The sky-island Ligidium species fauna in southwest China is poorly known. Before this study, six of the seven sky-island species of the genus were known to be endemic to southwest China. In morphology, Ligidium species are often difficult to identify, and an appraisal of integrative taxonomy is needed.

First record of the genus Hemilepistus (Isopoda: Agnaridae) from China, with description of two new species.

The genus Hemilepistus Budde-Lund, 1879 is reported from China for the first time. Two new species of the subgenus H. (Hemilepistus) are described from Xinjiang Uygur Autonomous Region, northwest China: H.

Fluorinated leaning pillar[6]arene: synthesis, structure and selective iodide anion binding by anion-π interactions.

Anion recognition has continuously attracted significant attention due to its important role in environmental and biological sciences. Here, we have designed and synthesized an electron-deficient fluorinated leaning pillar[6]arene 1 that contains two tetrafluoro-benzene units. The electron-deficient fluorinated leaning pillar[6]arene 1 is capable of selectively recognizing iodide anions to form a host-guest complex with 1 : 1 stoichiometry driven by anion-π interactions.

A third species of Parakermania Vandel, 1973 (Isopoda: Oniscidea: Armadillidae) from China.

Parakermania longa sp. nov., the third species of the woodlouse genus Parakermania Vandel, 1973 is described and illustrated from China.

Detection of Aliphatic Aldehydes by a Pillar[5]arene-based Fluorescent Supramolecular Polymer with Vaporchromic Behavior.

The detection of volatile aliphatic aldehydes is of significance because of their chemical toxicity, physical volatility and widespread applications in chemical industrial processes. In this work, the direct detection of aliphatic aldehydes is tackled using a pillar[5]arene-based fluorescent supramolecular polymer with vaporchromic behavior. Thin films with strong orange-yellow fluorescence are prepared by coating the linear supramolecular polymer on glass sheets.

Effect and mechanism of BDNF/TrkB signaling on vestibular compensation.

Brain-derived neurotrophic factor (BDNF) regulates neuronal plasticity by targeting the tyrosine kinase B receptor (TrkB) receptor, but limited researches concentrate on the role of BDNF/TrkB signaling in vestibular compensation. In this study, rats with unilateral vestibular dysfunction were established by unilateral labyrinthectomy (UL) and infusion with siBDNF or 7, 8-Dihydroxyflavone (7,8-DHF, a TrkB receptor agonist). The behavioral scores of rats with vestibular deficits were determined and the rotarod test was performed after UL.

Efficacy of High-Flow Nasal Cannula Oxygen Therapy in Patients with Mild Hypercapnia.

Objectives: To investigate the indications of high-flow nasal cannula (HFNC) oxygen therapy among patients with mild hypercapnia and to explore the predictors of intubation when HFNC fails.

Methods: This retrospective study was conducted based on the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Adult patients with mild hypercapnia (45 < PaCO ≤ 60 mmHg) received either HFNC or non-invasive ventilation (NIV) oxygen therapy.

Integrative taxonomy reveals a new species of the genus (Isopoda, Philosciidae) from the Xuefeng Mountains, China.

Three species of the genus are identified from the Xuefeng Mountains, central China, by integrating morphological and molecular approaches. Li, is described. Morphological photographs of the new species are provided.

SLCO4A1-AS1 regulates laryngeal squamous cell carcinoma cell phenotypes via the Wnt pathway.

Aim: Long non-coding RNAs were widely reported to regulate laryngeal squamous cell carcinoma (LSCC), a prevalent tumor in the head and neck. We aimed to investigate the role of solute carrier organic anion transporter family member 4A1 antisense RNA 1 (SLCO4A1-AS1) in LSCC.

Materials & Methods: CCK-8 and colony formation assays were conducted to examine the viability and proliferation of LSCC cells.

Immunotherapy-Associated Pancreatic Adverse Events: Current Understanding of Their Mechanism, Diagnosis, and Management.

Immune checkpoint inhibitors (ICIs) such as anti-programmed death-1 (PD-1) and its ligand PD-L1 and anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) monoclonal antibodies, are involved in T cell-mediated immune response augmentation and promote anti-tumor immunity. Cancer patients treated with combination of immunotherapy, chemotherapy, radiotherapy, and targeted therapy exhibit superior clinical outcomes and tolerance compared with patients treated with monotherapies. However, immutherapy is associated with several concomitant immune-related adverse events (irAEs).

First record of the genus Meyrick (Lepidoptera, Crambidae) from China, with description of a new species.

The genus has two species with an Australian distribution. The present study aims to record the genus from China for the first time and to add a third species, Jie & Li, to the genus. The new species can be distinguished from the congeners by the antemedial line connecting the postmedial line near the dorsum in the hindwing, and the phallus with a cluster of spine-like cornuti in the male genitalia.

[Impact of post-thoracotomy analgesia with dexmedetomidine and morphine on immunocytes: a randomized clinical trial].

Objective: This study aimed to investigate the impact of post-thoracotomy analgesia with dexmedetomidine and morphine on immunocytes.

Methods: A total of 118 patients with post-thoracotomy Patient-Controlled Intravenous Analgesia (PCIA) in our hospital from March 2016 to July 2018 were randomly selected and divided into the Composite (COM) Group (57 patients administered with dexmedetomidine [1.0 μg.

A Clinical Study of the Intra-Neuroendoscopic Technique for the Treatment of Subacute-Chronic and Chronic Septal Subdural Hematoma.

The surgical technique, safety, efficacy, and clinical application value of the intra-neuroendoscopic technique (INET) for the treatment of subacute-chronic and chronic septal subdural hematoma was investigated based on the structure and pathological features of the hematoma wall, and the critical factors of hematoma growth and recurrence were determined, in order to provide reference for clinical drug treatment. This was non-randomized concurrent control study. A total of 94 patients who met the inclusion criteria were recruited between May 2015 and February 2019 and were divided into the INET treatment group (INET group, 45 cases) and the burr hole drainage (BHD) treatment group (control group, 49 cases).

The geographical distribution patterns of Hübner in China and description of a new species (Lepidoptera, Crambidae).

The geographical distribution patterns of Hübner in China are analysed with MaxEnt and ArcGIS based on known localities and nineteen environmental variables. The results suggest that southeastern China is a highly suitable area, and Bio11 (mean temperature of the coldest quarter), Bio12 (annual precipitation) and Bio18 (precipitation of the warmest quarter) are revealed to be the main variables affecting the present distribution patterns. Among them, Bio18 is the strongest predictor with a 24.

Notes on (Lepidoptera, Crambidae) from China, with descriptions of two new species.

Two new species belonging to the genus Meyrick, 1938 are described from southwest China: and The female of Song & Chen, 2002 is described for the first time. The geographical distribution of the genus in China is analysed. The precipitation of the warmest quarter is revealed to be the strongest predictor affecting the present distribution pattern of the genus.

A new species of Kwon (Isopoda: Oniscidea: Agnaridae) from China.

Lucasioides nudus sp. n. is described from Jiangxi Province, China.