Dyson sphere-like evaporators enhanced interfacial solar evaporation via self-generated internal convection.

Enhancing solar evaporation performance while minimizing material consumption is essential for advancing the practical application of interfacial solar evaporation technologies. Although introducing external airflow can significantly boost evaporation rates, it requires additional components and electricity input, compromising the simplicity, passivity and sustainability of interfacial solar evaporation. To address this challenge, Dyson sphere-like evaporators (DSEs) capable of self-generating convective flow inside the evaporator are designed.

CHAC1 in urological tumors: contextual dualism and therapeutic implications.

CHAC1, a glutathione-degrading enzyme, governs context-dependent pathophysiological processes in urological malignancies through modulation of endoplasmic reticulum stress and ferroptotic pathways. In clear cell renal cell carcinoma (ccRCC), CHAC1 exhibits stage-specific functional duality: downregulation in early-stage tumors correlates with adverse prognosis (suggesting tumor-suppressive activity), whereas elevated expression in advanced ccRCC (G3-G4/Stage III-IV) associates with increased mortality (indicating adaptive pro-survival adaptation). For prostate cancer, CHAC1 potentiates docetaxel cytotoxicity via coordinated induction of endoplasmic reticulum stress and ferroptosis, yet its suppression by cancer-associated fibroblast-derived exosomal miR-432-5p establishes therapy-reinforced chemoresistance.

Innovative design and comprehensive ergonomic assessment of an auxiliary colonoscopy handle device.

Colonoscopy is a critical tool for diagnosing and treating bowel diseases, yet it demands high physician skill and can lead to suboptimal patient experiences. Recent technological advancements have aimed to enhance colonoscopy procedures by improving ease of use and patient comfort. This study introduces a novel colonoscopy handle auxiliary device designed to reduce operator fatigue and improve work efficiency.

Cortical changes induced by increased cognitive task difficulty during dual task balancing correlate with postural instability in elders and patients with Parkinson's disease.

. The flexibility of cognitive resource allocation is deteriorated due to aging and neurological degenerative diseases, such as Parkinson's disease (PD). Dual task performance reflects a subject's ability to allocate cognitive resources, and the investigation of cortical activation changes during dual tasking can provide a deep insight into the reallocation of neural resources.

Tissue-specific transcriptome analysis in Propsilocerus akamusi provides novel insights into the regulatory mechanisms under deltamethrin exposure.

Deltamethrin is extensively utilized in agricultural pest control and its toxicological impacts on aquatic insects have drawn significant attention. However, the mechanisms of deltamethrin modulates gene expression framework in different tissues remain largely unknown. Herein, we selected non-biting midge, Propsilocerus akamusi (Diptera: Chironomidae), to investigate the gene repertoires in hemolymph, fat body, midgut and Malpighian tubules under the different concentrations of deltamethrin.

Tissue-specific decellularized extracellular matrix rich in collagen, glycoproteins, and proteoglycans and its applications in advanced organoid engineering: A review.

Decellularized extracellular matrix derived from specific organs represents a promising platform for organoid development, offering distinct advantages in tissue engineering. This matrix maintains the complex three-dimensional network of biological macromolecules secreted by tissue-specific cells, including collagen, glycoproteins, and proteoglycans. This extracellular matrix orchestrates cellular behaviors, such as proliferation, migration, and differentiation, while maintaining optimal tissue homeostasis.

Unraveling Parkinson's disease motor subtypes: A deep learning approach based on spatiotemporal dynamics of EEG microstates.

Background: Despite prior studies on early-stage Parkinson's disease (PD) brain connectivity and temporal patterns, differences between tremor-dominant (TD) and postural instability/gait difficulty (PIGD) motor subtypes remain poorly understood. Our study aims to understand the contribution of altered brain network dynamics to heterogeneous motor phenotypes in PD for improving personalized treatment.

Methods: Electroencephalography (EEG) microstate dynamics were firstly used to capture spatiotemporal brain network changes.

Synchronously Restraining the Phase Transition and Structural Defect through a Unique Dopant Strategy for Manganese-Based Layered Cathodes for Sodium-Ion Batteries.

The P2-type sodium manganese-based layered oxide cathodes suffer from an unsatisfactory phase transition and structural defects due to the instability of the bulk and interfacial structure. In this work, we proposed a manganese-based layered oxide cathode, P2-NaNiMnO@FeO@TaO (Na2575-Fe-Ta), to increase the bulk and interfacial stability synchronously during cycling. Partially substituting Fe ions into the TMO layer in the bulk lattice structure mitigates the unfavorable phase transition and suppresses the variation of the lattice parameters during charge and discharge, retarding structural degradation.

Distribution and migration characteristics of Cs, Pu, and natural radioactive nuclides in the soil of Leye Tiankeng, China.

To investigate the distribution characteristics of radioactive nuclides in the soil of typical karst Tiankeng areas, two soil core samples and thirty surface soil samples were collected from the Leye Tiankeng Group, northwest Guangxi province in China. The soil's vertical distribution of U, Th, Ra, and K is uniform. Furthermore, the distribution trends of U, Th, and Ra in the surface soil are similar.

Environmental correlates of the distribution characteristics of artificial radionuclides (Cs, Pu, Np) in the northeast China.

This work focuses on the correlation between the distribution of artificial radionuclides cesium(Cs), plutonium(Pu), and neptunium(Np) and regional environmental factors in northeast China (NEC). For soil/sediment in this work, HPGe was used for Cs measurements and ICP-MS for Pu isotope and Np measurements. The Cs, Pu, and Np activities of the surface samples were 0.

Comparison of perioperative outcomes of DaVinci robot and Hugo robot radical prostatectomy: A systematic review and meta-analysis.

Objective: To compare the safety and efficacy of radical prostatectomy with DaVinci robot and Hugo robot.

Methods: The system searches Embase, PubMed, Cochrane library, and Web of Science 4 database. The search time ranges from database creation to June 2024.

Improving the Performance of LiNiCoMnO via Ti& Nb Co-Modifications.

Ni-rich layer-structured materials are some of the most promising cathodes owing to their attractive reversible capacity and cost-effectiveness. When the Ni content is increased to 90% and higher, mechanical deterioration becomes serious and leads to accelerated cyclic degradation, since removable Li is ∼0.85, accompanied by large lattice variation during operation.

BET degrader exhibits lower antiproliferative activity than its inhibitor via EGR1 recruiting septins to promote E2F1-3 transcription in triple-negative breast cancer.

The bromodomain and extraterminal domain (BET) family proteins serve as primary readers of acetylated lysine residues and play crucial roles in cell proliferation and differentiation. Dysregulation of BET proteins has been implicated in tumorigenesis, making them important therapeutic targets. BET-bromodomain (BD) inhibitors and BET-targeting degraders have been developed to inhibit BET proteins.

Bridged triphenylamine-based fluorescent probe for selective and direct detection of HSA in urine.

Human serum albumin (HSA) serves as a crucial indicator for therapeutic monitoring and biomedical diagnosis. In this study, a near infrared (NIR) fluorescent probe, termed BTPA, characterized a donor-π-acceptor (D-π-A) structure based on bridged triphenylamine (TPA) was developed. BTPA exhibited outstanding sensitivity and selectivity towards HSA among various analysts, with a remarkable 50-fold fluorescence enhancement with a significant Stokes shift (∼190 nm) and a wide linear detection range of 0-20 μM of HSA.

Scalable Multi-FPGA HPC Architecture for Associative Memory System.

Associative memory is a cornerstone of cognitive intelligence within the human brain. The Bayesian confidence propagation neural network (BCPNN), a cortex-inspired model with high biological plausibility, has proven effective in emulating high-level cognitive functions like associative memory. However, the current approach using GPUs to simulate BCPNN-based associative memory tasks encounters challenges in latency and power efficiency as the model size scales.

Is Ablation Suitable For Small Renal Masses? A Meta-Analysis.

Rationale And Objectives: To compare perioperative and oncology outcomes of ablation and partial nephrectomy in small renal masses (SRMs).

Methods: We conduct this meta-analysis strictly according to the PRISMA standard, and the quality evaluation follows the AMSTAR standard. Four databases, Embase, PubMed, Cochrane Library, and Web of Science, were systematically searched.

Comparing the safety and effectiveness of minimally invasive surgery and open inguinal lymph node dissection in penile cancer: A systematic review and meta-analysis.

Objective: To compare the safety and effectiveness of minimally invasive surgery (MIS) with open inguinal lymph node dissection (O-ILND) in penile cancer.

Methods: We performed a systematic reviews and cumulative meta-analyses of primary results of interest according to PRISMA criteria, and quality assessment followed AMSTAR. The system searched five databases, including Zhiwang, Embase, PubMed, Cochrane Library and Web of Science.

YEATS domain-containing protein GAS41 regulates nuclear shape by working in concert with BRD2 and the mediator complex in colorectal cancer.

The maintenance of nuclear shape is essential for cellular homeostasis and disruptions in this process have been linked to various pathological conditions, including cancer, laminopathies, and aging. Despite the significance of nuclear shape, the precise molecular mechanisms controlling it are not fully understood. In this study, we have identified the YEATS domain-containing protein 4 (GAS41) as a previously unidentified factor involved in regulating nuclear morphology.

MgNiO as a Ceramic Additive To Improve the Durability of Lithium Metal Anode.

Ceramic materials are the most popular additives to regulate the reinless interfacial reaction between lithium and the electrolyte by strengthening the SEI layer or tuning lithium deposition. Here, we propose an exceptional material, MgNiO, abbreviated as MN, which can improve the durability of lithium metal anode. Since it is undecomposed up to 0 V vs Li/Li, the MN's particles give some semiconductive characteristics to the SEI layer to tune the interfacial reactions.

A study of the mediating effect of social support on self-disclosure and demoralization in Chinese older adult homebound breast cancer patients.

Purpose: Demoralization is common in older adult homebound breast cancer patients, seriously affecting their quality of life. This study aimed to investigate the demoralization of older adult homebound breast cancer patients and to analyse the mediating effects of social support between self-disclosure and demoralization.

Methods: The study enrolled 368 older adult homebound breast cancer patients reviewed in outpatient clinics of three hospitals from January 2022 to August 2023.

Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.

Polyamines are a class of small polycationic alkylamines that play essential roles in both normal and cancer cell growth. Polyamine metabolism is frequently dysregulated and considered a therapeutic target in cancer. However, targeting polyamine metabolism as monotherapy often exhibits limited efficacy, and the underlying mechanisms are incompletely understood.

Large Organic Polar Molecules Tailored Electrode Interfaces for Stable Lithium Metal Battery.

Lithium (Li) metal batteries (LMBs) are deemed as ones of the most promising energy storage devices for next electrification applications. However, the uneven Li electroplating process caused by the diffusion-limited Li transportation at the Li metal surface inherently promotes the formation of dendritic morphology and instable Li interphase, while the sluggish Li transfer kinetic can also cause lithiation-induced stress on the cathode materials suffering from serious structural stability. Herein, a novel electrolyte designing strategy is proposed to accelerate the Li transfer by introducing a trace of large organic polar molecules of lithium phytate (LP) without significantly altering the electrolyte structure.

Binding FSI to Construct a Self-Healing SEI Film for Li-Metal Batteries by In situ Crosslinking Vinyl Ionic Liquid.

The solid electrolyte interphase (SEI) membrane on the Li metal anode tends to breakdown and undergo reconstruction during operation, causing Li metal batteries to experience accelerated decay. Notably, an SEI membrane with self-healing characteristics can help considerably in stabilizing the Li-electrolyte interface; however, uniformly fixing the repairing agent onto the anode remains a challenging task. By leveraging the noteworthy film-forming attributes of bis(fluorosulfonyl)imide (FSI) anions and the photopolymerization property of the vinyl group, the ionic liquid 1-vinyl-3-methylimidazolium bis(fluorosulfonyl)imide (VMI-FSI) was crosslinked with polyethylene oxide (PEO) in this study to form a self-healing film fixing FSI groups as the repairing agent.