Nat Commun
August 2025
The high cost and complexity of fabrication limit the large-scale application of flexible inorganic thermoelectric materials. Currently, BiTe-based materials are the only commercially viable option, but the inclusion of Te significantly increases production costs. This study presents a simple and cost-effective method for fabricating flexible AgSe films, employing a combination of solvothermal synthesis, screen printing, and spark plasma sintering.
View Article and Find Full Text PDFIntroduction: Nasal spray films, an innovative formulation in recent years, have garnered significant acclaim from patients with nasal mucosal injury because it integrate the benefits of spray and film formulation, offering ease of application while reducing the risk of droplet formation and further inhalation into the throat. Furthermore, Lithospermum erythrorhizon is a traditional Chinese medicine frequently employed in the management of dermal injuries, and our previous work suggested its major compound, shikonin, possesses the capacity to promote the repair of nasal mucosal injury. Notwithstanding these encouraging results, research on the development of shikonin nasal spray film preparation (SNSF) and its bioactivity mechanism remains limited.
View Article and Find Full Text PDFNat Chem Biol
June 2025
Abnormal aggregation of amyloid-β protein (1-42) (Aβ) is the primary pathology in Alzheimer's disease (AD). Two types of Aβ fibrils have been identified in the insoluble fraction of diseased human brains. Here, we report that the fraction previously deemed 'soluble' during sarkosyl extraction of AD brains actually harbors numerous amyloid fibrils, with a looser bundling than those in the insoluble fraction.
View Article and Find Full Text PDFJ Colloid Interface Sci
November 2025
Single-walled carbon nanotubes (SWCNTs) with unique electronic structures, high electrical conductivity and processability have shown great promise for flexible thermoelectric devices. However, the inherently high thermal conductivity of SWCNTs significantly constrains their thermoelectric performance. To overcome this limitation, this study presents a composite of SWCNTs hybridized with the strategically selected cuprous selenide (CuSe) through cold pressing.
View Article and Find Full Text PDFThe widespread use of plastic agricultural films necessitates a thorough evaluation of environmental risks posed by soil microplastics (MPs). While the intestinal tract is a critical site for MP interactions in soil organisms, current research predominantly focuses on overall physiological responses, overlooking organ-specific toxic mechanisms. To address this gap, we exposed earthworms () to polyethylene (PE) and biodegradable polylactic acid (PLA) MPs sourced from agricultural films at an environmentally realistic concentration of 1.
View Article and Find Full Text PDFAgCu(Te, Se, S) alloys, as one of the rare p-type plastic inorganic thermoelectrics, are receiving striking attention for their application foreground in high-performing flexible thermoelectric generators. However, strategies to enhance their thermoelectric performance while maintaining exceptional plasticity remain largely unexplored. Here, we introduce a strategic vacancy-engineering approach to address this challenge.
View Article and Find Full Text PDFAs advancements in Mg-based thermoelectric materials continue, increasing attention is directed toward enhancing the thermoelectric performance of MgSb and its integration into thermoelectric devices. However, research on MgSb thin films and their application in flexible devices remains limited, leaving ample room for improvements in fabrication techniques and thermoelectric properties. To address these gaps, this study employs magnetron sputtering combined with ex-situ annealing to dope Bi into MgSb thin films, partially substituting Sb.
View Article and Find Full Text PDFEnhancing the thermoelectric performance of AgSe thin films via physical vapor deposition remains challenging. In this study, a precursor doping strategy is introduced to fabricate In-doped AgSe thin films. In substitutional doping at the Ag cation sites increases the charge density distribution of AgSe, improving electrical conductivity, while maintaining a high Seebeck coefficient and relatively low thermal conductivity.
View Article and Find Full Text PDFBiomed Mater Eng
January 2025
Background: Nanomaterials have applications in traditional Chinese medicine in the fields of medical equipment manufacturing, targeted transportation, and drug synergistic therapy.
Objective: The research aims to discuss the performance and performance of zinc-iron-based nanomaterials in medical drug delivery and synergistic drug therapy.
Methods: Using Prussian materials as precursors, magnetic zinc-iron nanomaterials were prepared by ZnCl and K[Fe (CN)].
Nat Commun
February 2025
The debate over the optimal orientation of AgSe thin films and its influence on thermoelectric performance remains ongoing. Here, we report a wet-chemical selenization-based anisotropy optimization technique to control the in-plane orientation of the AgSe thin film, steering it away from (002) nearly parallel planes that hinder charge carrier mobility. This approach enables us to achieve an impressive power factor of 30.
View Article and Find Full Text PDFHere, we design exotic interfaces within a flexible thermoelectric device, incorporating a polyimide substrate, Ti contact layer, Cu electrode, Ti barrier layer, and thermoelectric thin film. The device features 162 pairs of thin-film legs with high room-temperature performance, using p-BiSbTe and n-BiTeSe, with figure-of-merit values of 1.39 and 1.
View Article and Find Full Text PDFOsteoarthritis (OA) is the primary cause of disability worldwide. Chondrocyte apoptosis has important implications for OA onset and progression. This work was designed to explore the mechanisms of chondrocyte apoptosis in OA and identify key chondrocyte apoptosis-related genes (CARGs).
View Article and Find Full Text PDFJ Biol Chem
November 2024
The aggregation of α-synuclein (α-syn) into amyloid fibrils, a key process in the development of Parkinson's disease (PD) and other synucleinopathies, is influenced by a range of factors such as charged biopolymers, chaperones, and metabolites. However, the specific impacts of different biopolymers on α-syn fibril structure are not well understood. In our work, we found that different polyanions and polycations, such as polyphosphate (polyP), polyuridine (polyU), and polyamines (including putrescine, spermidine, and spermine), markedly altered the fibrillation kinetics of α-syn in vitro.
View Article and Find Full Text PDFAgSe shows significant potential for near-room-temperature thermoelectric applications, but its performance and device design are still evolving. In this work, we design a novel flexible AgSe thin-film-based thermoelectric device with optimized electrode materials and structure, achieving a high output power density of over 65 W m and a normalized power density up to 3.68 μW cm K at a temperature difference of 42 K.
View Article and Find Full Text PDFWith the increasing demand for energy and the climate challenges caused by the consumption of traditional fuels, there is an urgent need to accelerate the adoption of green and sustainable energy conversion and storage technologies. The integration of flexible thermoelectrics with other various energy conversion technologies plays a crucial role, enabling the conversion of multiple forms of energy such as temperature differentials, solar energy, mechanical force, and humidity into electricity. The development of these technologies lays the foundation for sustainable power solutions and promotes research progress in energy conversion.
View Article and Find Full Text PDFIntroduction: This study addresses the urgent need for non-destructive identification of commercially valuable species, which are threatened by illegal logging. Effective identification methods are crucial for ecological conservation, biodiversity preservation, and the regulation of the timber trade.
Methods: We integrate Visible/Near-Infrared (Vis/NIR) Hyperspectral Imaging (HSI) with advanced machine learning techniques to enhance the precision and efficiency of wood species identification.
Single-walled carbon nanotubes (SWCNTs)-based thermoelectric materials, valued for their flexibility, lightweight, and cost-effectiveness, show promise for wearable thermoelectric devices. However, their thermoelectric performance requires significant enhancement for practical applications. To achieve this goal, in this work, we introduce rational "triple treatments" to improve the overall performance of flexible SWCNT-based films, achieving a high power factor of 20.
View Article and Find Full Text PDFDue to the direct conversion between thermal and electrical energy, thermoelectric materials and their devices exhibit great potential for power generation and refrigeration. With the rapid development of personal wearable electronics, the design of flexible inorganic thermoelectric materials and devices receives increasing attention. As one of the most mature thin-film fabrication techniques, magnetron sputtering plays a key role in the fabrication of inorganic thermoelectric thin films and devices, but its progress is still not timely and comprehensively reviewed.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
June 2023
In order to explore practical ways to test the eco-efficiency of low-carbon tourism and its drivers in Jiangsu Province, this paper empirically tests the effects of selected driving variables on the eco-efficiency of low-carbon tourism using a spatial lag model. It measures the eco-efficiency of low-carbon tourism in 13 prefecture-level cities in Jiangsu Province based on a modified two-stage network SBM model. According to the direct effect test results, per capita tourism income (PTI) had the most significant effect on the eco-efficiency of low-carbon tourism, with an impact coefficient of 0.
View Article and Find Full Text PDFMitochondrial DNA B Resour
January 2023
The rhizome of is one of the most commonly used herbs in China. In this paper, we presented the complete chloroplast genome of . The chloroplast genome of is 153,256 bp in length as the circular, which harbors a large single-copy (LSC) region 84,291 bp, a small single-copy (SSC) region of 18,675 bp and separated by a pair of inverted-repeat (IR) regions of 25,145 bp for each one.
View Article and Find Full Text PDFAs green, safe, and cheap solvents, deep eutectic solvents (DESs) provide tremendous opportunities to open up attractive perspectives for electrocatalysis. In this review, the achievement of DESs in the preparation of catalysts for electrolytic water splitting is described in detail according to their roles combined with our own work. DESs are generally employed as green media, templates, and electrolytes.
View Article and Find Full Text PDF. Automatic segmentation of MRI brain tumor area is a key step in the diagnosis and treatment of brain tumor. In recent years, the improved network based on UNet encoding and decoding structure has been widely used in brain tumor segmentation.
View Article and Find Full Text PDFComput Math Methods Med
March 2022
Background: Tendon-to-bone healing is a difficult process in treatment of rotator cuff tear (RCT). In addition, diabetes is an important risk factor for poor tendon-to-bone healing. Therefore, we investigated the specific mechanisms through which diabetes affects tendon-to-bone healing by regulating the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
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