Publications by authors named "Thu Thi Hoai Nguyen"

Background: Preventing frailty is crucial for improving outcomes in aging populations at heightened cardiovascular risk, yet implementation in real-world practice remains challenging. The authors previously reported low use of frailty strategies among cardiologists in Asia.

Objectives: The aim of this study was to explore the barriers to frailty implementation among cardiologists, other physicians, and nurses.

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Objectives: The aims of the study were to investigate the proportion of frailty among inpatients having Acute Coronary Syndrome (ACS) and to compare the prognostic value of three frailty screening methods in predicting in-hospital adverse events among the study population.

Methods: This prospective, observational study design was conducted on older patients with ACS. Data was collected using a structured questionnaire on general characteristics (age, gender, comorbidities, body mass index) and medical records (admission diagnosis, ACS type, angiography results, treatment therapy, left ventrical ejection fraction, and length of hospital stay).

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In our search for bioactive natural products from the lichen species in Vietnam, Usnea aciculifera Vain (Parmeliaceae) in particular, two new depsides (1 and 2), one new monocyclic phenolic (3), and seven known (4-10) were isolated. The α-glucosidase inhibitory ability of 1-10 was assessed in vitro and further analyzed by molecular docking. Besides, the two new depsides were also assayed for their cytotoxicity against three human cancer cell lines (KB, MCF-7, and HepG2) and a normal human lung fibroblast (WI-38).

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Aim: To determine the prevalence and factors associated with sarcopenia in rheumatoid arthritis (RA) patients at a central university hospital in Hanoi, Vietnam.

Methods: Patients with RA aged ≥ 18 were enrolled in this cross-sectional study. Dual-energy X-ray absorptiometry was performed to measure appendicular skeletal muscle (ASM).

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Background: Information technology can be used to improve the management of non-communicable diseases, such as diabetes. This study aims to evaluate the willingness of older outpatients with type 2 diabetes to use mobile phones to support medication adherence and receive text message appointment reminders and investigated the factors associated with this willingness.

Methods: This study was a cross-sectional study conducted at the outpatient department of Dong Da General Hospital.

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Article Synopsis
  • Vietnam is experiencing a significant rise in dementia cases, prompting the need for effective interventions for family caregivers.
  • A study tested a culturally adapted program (REACH VN) against a basic education session for caregivers, measuring psychological distress and burden over 3 and 6 months.
  • Results showed that while REACH VN helped reduce caregiver distress and burden at 3 months, most improvements did not persist after 6 months.
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  • Nurses' competencies are vital for effective dementia care, making it important to assess their knowledge, attitudes, and confidence about the subject for better education and patient care outcomes.
  • A survey was conducted with 269 nurses in Hanoi, using three self-administered questionnaires to evaluate their dementia care knowledge, attitudes, and confidence levels.
  • Results showed that while there is a positive correlation among knowledge, attitudes, and confidence, there are notable deficits, indicating a need for improved training and exposure to dementia care scenarios.
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Article Synopsis
  • * Researchers found that all participants experienced multiple geriatric syndromes, with an average of five per person, highlighting issues like loss of independence and reduced lower body strength.
  • * The study emphasizes the need for improved healthcare strategies to assess and address these syndromes in older adults with dementia in Vietnam.
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This research aimed to explore factors associated with the fear of falling (FOF) among community-dwelling older adults in Vietnam. A cross-sectional study was conducted in five communes in Soc Son, Hanoi, Vietnam, from March to June 2017. We recruited a total of 487 participants, which provided sufficient data for analysis.

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Objective: To identify the efficacy and tolerability of Proteoglycan F in patients with primary knee OA.: A 24-week randomized, placebo-controlled, double-blind clinical trial with two arms: (1) Proteoglycan F (received 10 ​mg proteoglycan daily, for 24 weeks) and (2) control group (received placebo). Knee symptoms and joint cartilage status (evaluated by ultrasound and MRI of knee joints), quality of life, serum cytokine levels IL-1β and TNF-α), and safety evaluation were measured before, during, and after the treatment.

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Better understanding of the quality of life among nursing home residents with dementia is important for developing interventions. The objectives of this cross-sectional study were to examine factors associated with poor health-related quality of life in older people with dementia living in nursing homes in Hanoi, Vietnam. In-person interviews were conducted with 140 adults who were 60 years and older with dementia, and information about their quality of life was obtained using the Quality of Life in Alzheimer's Disease (QOL-AD) scale.

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Background: As Vietnam and other low- and middle-income countries (LMIC) experience a rapid increase in the number of people living with dementia, an acute need exists to strengthen research capacity to inform policy, improve care and support, and develop national dementia plans. We describe the development and early outcomes of an National Institutes of Health (NIH)/National Institute on Aging (NIA)-funded national dementia research capacity building program in Vietnam.

Methods: The research capacity building program commenced in 2019 and has three components: (1) Vietnam Alzheimer's and other dementias research Network (VAN), (2) a mentored pilot grant program, and (3) research training, networking, and dissemination activities.

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Objectives: This study aimed to investigate the relationship between sarcopenia and frailty and examine factors associated with frailty among older patients with and without sarcopenia.

Methods: This cross-sectional study was conducted on older inpatients and outpatients in Vietnam. Participants aged 60 years or older were consecutively enrolled in the study.

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Purpose: The aim of this study was to explore the impact of frailty on in-hospital adverse outcomes and net adverse clinical events (NACE) in older patients with acute coronary syndrome.

Patients And Methods: This observational study included elderly patients (≥60 years old), diagnosed with acute coronary syndrome (ACS) at admission from February 2021 to August 2021. The primary outcome was net adverse clinical events (NACE) defined as a composite of all-cause mortality, stroke, and major bleeding.

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Introduction: Thyroid nodules are common diseases of the endocrine system, with a 5% prevalence rate in the general population. This study aimed to identify prevalence, clinical, cytological and ultrasonographic features of incidental thyroid cancer and its associated factors in Vietnam.

Methods: This cross-sectional descriptive study consisted of 208 patients with incidental thyroid nodules detected by ultrasound at the Endocrinology Department, Bach Mai Hospital, Hanoi, Vietnam between November 2019 and August 2020.

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Purpose: This study aimed to determine the prevalence of post-stroke depression (PSD) during the first year and its associated factors, especially focusing on sleep quality and fatigue severity.

Methods: A cross-sectional study was conducted among stroke patients in Vietnam's National Geriatric Hospital. Data were collected by using standardized questionnaires for interviewing and evaluating patients at the research site.

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This study aimed to assess the symptom burden among older patients hospitalised for heart failure. This hospital-based, cross-sectional study was conducted at the National Geriatric Hospital, Hanoi, Vietnam, from June 2019 to August 2020. Face-to-face interviews were performed to gather the following information: socio-demographic characteristics, heart failure classification, and clinical characteristics (comorbidities, polypharmacy, pro-B-type natriuretic peptide, left ventricular ejection fraction (LVEF), symptom burden, and depression).

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This study aims to provide data on usual walking speed in individuals aged 80 years or older and determine the association between walking speed and related factors in community-dwelling older adults. A cross-sectional study design was conducted to measure walking speed on community-dwelling elders aged 80 years or older in Soc Son district, Vietnam. Walking speed was assessed by a 4-Meter Walk Test with a usual-pace walking mode.

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Background: Vietnam has encountered difficulties in ensuring an adequate and equitable distribution of health workforce. The traditional staffing norms stated in the Circular 08/TT-BYT issued in 2007 based solely on population or institutional size and do not adequately take into consideration the variations of need such as population density, mortality and morbidity patterns. To address this problem, more rigorous approaches are needed to determine the number of personnel in health facilities.

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Introduction: Comprehensive geriatric assessment (CGA) of older diabetic patients is thought to be of value, but there have been limited studies on the prevalence of impairments in the components of a CGA as well as the relationship between CGA and diabetic control in this group.

Objective: This study aimed to evaluate the prevalence of components of CGA in older patients with diabetes in National Geriatric Hospital, Hanoi, Vietnam, and determine the association among domains of CGA with measures of diabetic control.

Methods: A cross-sectional study of diabetic outpatients aged ≥60 years at National Geriatric Hospital in Hanoi, Vietnam, recruited over 3 months.

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The interaction of chronic pain and depression among older people has been studied for many years. This study aimed to investigate the frequency of chronic pain and depression among older patients and correlated factors. A cross-sectional study was conducted in 921 older patients at the National Geriatric Hospital from November 2019 to March 2020.

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Objectives: This study investigated associations between frailty and functional disability in elder suburban Vietnamese.

Method: Cross-sectional analysis was carried out on 251 participants aged 80 and over in Soc Son district. We used the Instrumental Activities of Daily Living (IADL) scale including 8 items, and functional disability was defined as ≥3 IADL impairment.

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Objective: To describe handgrip strength (HGS) and identify associated factors in community-dwelling older adults in rural Vietnam.

Methods: A cross-sectional study was conducted in community-dwelling older adults 80 years and over in five rural communities in Hanoi, Vietnam. Age-gender-BMI stratified HGS values were reported as means and standard deviations.

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Nitrous oxide (NO) commonly referred to as laughing gas, has significant medical uses. This study aims to describe the neurological disorders associated with NO. We conducted across-sectional study that enrolled patients with nitrous oxide toxicity admitted to Vietnam Poison Control Center, Bach Mai Hospital, Hanoi, Vietnam from June 2018 to July 2019.

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