Addressing Frailty in Cardiology: Identifying Barriers Faced by Cardiologists and Health Care Professionals in Asia.

Background: Preventing frailty is crucial for improving outcomes in aging populations at heightened cardiovascular risk, yet implementation in real-world practice remains challenging. The authors previously reported low use of frailty strategies among cardiologists in Asia.

Objectives: The aim of this study was to explore the barriers to frailty implementation among cardiologists, other physicians, and nurses.

Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults.

Background: Among older adults, sex hormones may exert differential effects on body fat and cardiac health.

Objectives: The authors aimed to study the effects of sex on body fat composition and aging-related diastolic function, as well as their longitudinal changes.

Methods: Community-dwelling older adults without cardiovascular disease underwent prospective baseline same-day anthropometry for body fat mass (BFM), percentage body fat (PBF), and waist hip ratio (WHR) quantification by bioimpedance and transthoracic Doppler echocardiography, with measurements repeated at 5 years.

Superior aortic strain and ventriculoarterial coupling in older women are moderately correlated with Framingham 10-year risk.

Aims: Traditional risk factors do not fully characterize cardiovascular aging and are less helpful in assessing sex differences in cardiovascular risk. Using a novel cardiovascular magnetic resonance (CMR) method, we determined sex differences in aortic global longitudinal strain (AOGLS) and ventriculoarterial coupling (VAC) with correlations to Framingham risk scores.

Methods And Results: Community older adults without cardiovascular disease underwent CMR.

Effect of Frailty on Cardiovascular Clinical Trials: A Systematic Review and Meta-Analysis.

Background: Patients with cardiovascular (CV) diseases are increasingly frail but rarely represented in trials. Understanding effect modification by frailty on CV trials is critical as it could help define treatment strategies in frail patients.

Objectives: This meta-analysis aims to assess the implications of frailty on CV outcomes in clinical trials.

Periprocedural care for frail older patients with aortic stenosis undergoing transcatheter aortic valve replacement.

Degenerative aortic stenosis (AS) is an aging-associated disease with alarmingly high mortality that has risen in prevalence in tandem with the global population aging. Treatment options for AS are currently limited to surgical or percutaneous valve intervention, which are associated with significant morbidity. It is increasingly recognized that the care of AS patients is frequently constrained by concomitant frailty, an under-recognized syndrome among older individuals.

The GLOB-cAGE consortium: a global cardiovascular collaborative network of older adults with cardiovascular disease.

The Global Cardiovascular Collaborative Network of Older Adults with Cardiovascular Disease (GLOB-cAGE) is a newly established, unprecedented consortium that brings together cohorts of older individuals with cardiovascular disease (CVD) worldwide. The GLOB-cAGE aims to harmonize nonidentifiable data from longitudinal cohorts examining cardiovascular health and CVD diagnosis and management in older individuals to perform meta-regression analyses using combined repositories of standardized subject-level data points. Studies registered into GLOB-cAGE are population-based longitudinal cohort studies or clinical trials, either ongoing or completed, that involve assessing cardiovascular health as a central objective.

Effects of short-term moderate intensity exercise on the serum metabolome in older adults: a pilot randomized controlled trial.

Background: We previously reported changes in the serum metabolome associated with impaired myocardial relaxation in an asymptomatic older community cohort. In this prospective parallel-group randomized control pilot trial, we subjected community adults without cardiovascular disease to exercise intervention and evaluated the effects on serum metabolomics.

Methods: Between February 2019 to November 2019, thirty (83% females) middle-aged adults (53 ± 4 years) were randomized with sex stratification to either twelve weeks of moderate-intensity exercise training (Intervention) (n = 15) or Control (n = 15).

Current frailty knowledge, awareness, and practices among physicians following the 2022 European consensus document on Frailty in Cardiology.

Aims: Aging-related cardiovascular disease and frailty burdens are anticipated to rise with global aging. In response to directions from major cardiovascular societies, we investigated frailty knowledge, awareness, and practices among cardiologists as key stakeholders in this emerging paradigm a year after the European Frailty in Cardiology consensus document was published.

Methods And Results: We launched a prospective multinational web-based survey via social networks to broad cardiology communities representing multiple World Health Organization regions, including Western Pacific and Southeast Asia regions.

Coronary Intravascular Lithotripsy Versus Rotational Atherectomy in an Asian Population: Clinical Outcomes in Real-World Patients.

Background And Objectives: We compared real-world clinical outcomes of patients receiving intravascular lithotripsy (IVL) versus rotational atherectomy (RA) for heavily calcified coronary lesions.

Methods: Fifty-three patients who received IVL from January 2017 to July 2020 were retrospectively compared to 271 patients who received RA from January 2017 to December 2018. Primary endpoints were in-hospital and 30-day major adverse cardiovascular events (MACE).

Observation of handover process in an intensive care unit (ICU): barriers and quality improvement strategy.

Objective: To describe the characteristics and barriers in the handover process in a medical intensive care unit.

Design: A cross-sectional descriptive study using a checklist to observe nurses and doctors during handover of patients in and out of the intensive care unit.

Setting: The study was conducted at a 1000-bed tertiary hospital in Singapore.

Differences in the handover process and perception between nurses and residents in a critical care setting.

Aims And Objectives: To identify the differences in practices and perceptions of handovers between nurses and residents in the critical care setting, so as to improve the quality of the process.

Background: Critically ill patients with complex problems are ideal for the study of handovers. However, few handover studies have been conducted in intensive care units.