Publications by authors named "Anh Thi Phuong Nguyen"

Objectives: Alzheimer's disease and related dementias (ADRD) pose a growing public health challenge in Vietnam. This study describes a community-based screening protocol to identify older adults and their primary family caregivers in Hai Duong province to support recruitment for a caregiver intervention clinical trial.

Methods: Village health workers were trained to identify older adults at risk for dementia using a simplified tool adapted from the California Alzheimer's Disease Centers' Assessment of Cognitive Complaints Toolkit.

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Background: This study evaluated the effectiveness of intrathecal autologous bone marrow mononuclear cell (BMMNC) therapy combined with education compared with education alone for the treatment of autism spectrum disorder (ASD).

Methods: Fifty-four children with ASD, aged three to seven years, were randomly assigned to two groups. Fifty patients completed the study (25 patients per group).

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Article Synopsis
  • Vietnam is experiencing a significant rise in dementia cases, prompting the need for effective interventions for family caregivers.
  • A study tested a culturally adapted program (REACH VN) against a basic education session for caregivers, measuring psychological distress and burden over 3 and 6 months.
  • Results showed that while REACH VN helped reduce caregiver distress and burden at 3 months, most improvements did not persist after 6 months.
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Background: The increasing needs of people living with dementia (PLWD) in Vietnam present an enormous public health challenge. Vietnam is an understudied country, and little is known regarding the overall unmet needs of caregivers or the demographic risk factors associated with unmet caregiving needs. This study aimed to determine the burden of unmet care needs of community-dwelling PLWD and identify sociodemographic risks associated with unmet care needs.

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Background: Premature ventricular contraction (PVC) is a common arrhythmia that causes a large number of clinical symptoms, adversely impacts the quality of life, and can even initiate serious arrhythmias, such as ventricular tachycardia or ventricular fibrillation. The incidence of premature ventricular contraction is higher in hypertensive patients, particularly if concomitant left ventricular hypertrophy (LVH) is present.

Objectives: This study was conducted on the characteristics of PVC in hypertensive patients with left ventricular hypertrophy and aimed to evaluate the effect of bisoprolol on PVC in Vietnamese patients with hypertension and LVH.

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Background: Tobacco kills more than 8 million people each year, mostly in low- and middle-income countries. In Vietnam, 1 in every 2 male adults smokes tobacco. Vietnam has set up telephone Quitline counseling that is available to all smokers, but it is underused.

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Article Synopsis
  • * Sixty family caregivers participated in a randomized trial comparing a culturally adapted intervention to a control group, with a majority completing the study.
  • * Results showed that caregivers in the intervention group experienced significantly lower levels of burden and psychological distress compared to the control group, indicating the intervention's effectiveness.
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  • A bacterium named Janibacter sp. TYM3221 was isolated and studied for its ability to degrade the pesticide 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (DDE), with a focus on understanding the enzyme systems necessary for this process.
  • Analysis revealed that TYM3221 converts DDE into five metabolites, including a key product linked to its degradation pathway—4-chlorobenzoic acid, which indicates a specific chemical transformation process.
  • A specific gene cluster (bphAaAbAcAd) responsible for a biphenyl-degrading enzyme was identified, and when this gene was inactivated, the mutant strain lost its ability to degrade both
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