Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Bacterial degradation of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (DDE) has been previously reported, however, its degradation enzyme system has not been characterized. In this study, a DDE-degrading bacterium, Janibacter sp. TYM3221, was isolated and characterized. Transformation of DDE was demonstrated by TYM3211 resting cells grown in LB in the presence and absence of biphenyl. Gas chromatography-mass spectrometry analysis revealed five metabolites of DDE containing a meta-ring cleavage product and 4-chlorobenzoic acid, suggesting that TYM3221 degrades DDE to 4-chlorobenzoic acid via a meta-ring cleavage product. A gene cluster, bphAaAbAcAd, which codes for biphenyl dioxygenase subunits, was cloned from TYM3221. A mutant strain with a bphAa-gene inactivation did not grow on biphenyl, and showed no DDE degradation activity. These results indicate that in strain TYM3221, the bphAa-coded biphenyl dioxygenase is involved not only in the metabolism of biphenyl but also in the degradation of DDE.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.enzmictec.2011.06.017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Intra-population isotopic niche variation in common bottlenose dolphins (Tursiops truncatus) from the northern Adriatic Sea.
Sci Total Environ
September 2025
Sea Mammal Research Unit, University of St Andrews, United Kingdom.
Among-individual variability in animal behaviour and diet leads to a plethora of mini-niches within a population's general niche. Such variability is directly or indirectly linked to inter- and intra-specific competition, behavioural adaptation and variation in foraging tactics, which may lead to evolutionary divergence and speciation but is also relevant to population resilience and conservation. We used boat surveys, photo-identification techniques, biopsy sampling and stable isotope analysis (δC, δN) to study the intra-population isotopic niche variation in an apex predator, the common bottlenose dolphin (Tursiops truncatus), in the northern Adriatic Sea.
View Article and Find Full Text PDFCleft lip and palate are associated with a higher prevalence of molar-incisor hypomineralisation: a cross-sectional study with a comparison group.
Eur Arch Paediatr Dent
September 2025
Department of Stomatology, Federal University of Paraná, Curitiba, Brazil.
Purpose: To assess the association between non-syndromic cleft lip and/or palate (NSCL/P) and developmental defects of enamel (DDE), including the DDE subtypes, such as molar-incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM).
Methods: This cross-sectional study with a comparison group included individuals with and without NSCL/P ("NSCL/P group" and "control group," respectively). The NSCL/P group was recruited from a specialised craniofacial centre, and the control group was randomly selected from a population-based sample of schoolchildren, in a 1:2 ratio.
Comprehensive evaluation of cleavable bioorthogonal probes for site-specific O-GlcNAc proteomics.
Mol Cell Proteomics
August 2025
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC 20007, USA. Electronic address:
O-linked β-N-acetylglucosamine (O-GlcNAc) modification (i.e., O-GlcNAcylation) on proteins is an essential modification in physiology and pathology.
View Article and Find Full Text PDFAcute, prolonged, and chronic exposure to organochlorine insecticides evoke differential effects on in vitro neuronal activity and network development.
Neurotoxicology
August 2025
Neurotoxicology Research Group, Division of Toxicology, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.177, Utrecht NL-3508 TD, the Netherlands. Electronic address:
Organochlorine insecticide exposure has been associated with neurodevelopmental and neurodegenerative disorders. Moreover, both in vitro and in vivo studies have shown that exposure to organochlorine insecticides causes hyperactivity in the nervous system, and negatively affects calcium homeostasis, neurite outgrowth, and neurotransmitter (receptor) levels. Some of the in vivo effects and associations from epidemiological studies were sex-specific, highlighting the importance of investigating the effects of organochlorine exposure in both sexes.
View Article and Find Full Text PDFThe Association Between Female Breast Size, Backache, and Quality of Life in Young Women: A Cross-Sectional Study.
Medicina (Kaunas)
July 2025
Department of Orthopedic Surgery, Wolfson Medical Center, Holon 5822012, Israel.
: The association between female breast size and spinal back pain is widely suggested in clinical practice but remains insufficiently quantified in general, non-surgical populations in the scientific literature. Larger breasts may increase biomechanical strain on the spine, contributing to musculoskeletal pain and reduced quality of life. This study aimed to evaluate the association between breast size and back pain in a general orthopedic population of young women.
View Article and Find Full Text PDF