Computed tomography manifestations of drug-induced liver injury according to type and severity of injury.

Background: Drug-induced liver injury (DILI) has become a major cause of acute liver failure, and its incidence has been increasing steadily in recent years. This study aimed to compare the clinical and computed tomography (CT) imaging features of the variable biochemical damage and severity of DILI to establish a radiological model for predicting high-risk DILI based on CT image features.

Methods: The eligible patients with DILI (January 2016 to March 2024) who underwent serum laboratory examination and contrast abdominal CT within 3 months of onset were retrospectively analyzed at Affiliated Xihu Hospital of Hangzhou Medical College (Institution I) and The Second Affiliated Hospital of Zhejiang Chinese Medical University (Institution II).

A scoring model based on MRI features for predicting early recurrence after surgical resection of hepatocellular carcinoma.

Objectives: Based on MRI features, a scoring model was constructed to predict early recurrence after surgical resection of hepatocellular carcinoma (HCC).

Methods: A total of 310 patients from two centers with HCC (212 in the training cohort, 98 in the validation cohort) were collected from January 2017 to October 2023, all patients underwent preoperative MRI-enhanced examinations and were pathologically diagnosed after resection and were divided into early recurrence group and non-early recurrence group based on follow-up results. Clinical, laboratory, and MRI features of patients were collected and subjected to statistical analysis.

Cold-season macrophyte-driven microbial modulation reduces nutrient release in eutrophic lake sediments.

Submerged macrophyte restoration can effectively regulate internal nutrient cycling in eutrophic lake sediments, yet how cold-season macrophytes influence sediment microbial processes remain poorly understood. In this study, we conducted a field enclosure experiment combined with metagenomic sequencing using Potamogeton crispus, a cold-season submerged macrophyte, to investigate its effects on nitrogen (N) and phosphorus (P) dynamics across the sediment-water interface. The restoration of P.

Uterine arteriovenous fistula: A case report and literature review.

Rationale: Uterine arteriovenous fistula (UAVF) is not very common and can occur after traumatic activities, such as surgery, delivery, miscarriage, and curettage. Previous studies have reported on the ultrasound and digital subtraction angiography (DSA) findings of UAVF; however, there are few reports on computed tomography (CT), CT angiography (CTA), and magnetic resonance imaging (MRI) findings. We report a case in which residual products of conception were diagnosed during an MRI, with an oversight of the presence of UAVF.

Role of vertebral fat fraction and R2* based on fat analysis and calculation technique in the quantitative assessment of osteoporosis.

Purpose: To investigate the diagnostic efficacy of vertebral fat fraction (FF) and R2* derived from the Fat Analysis and Calculation Technique (FACT) for Osteoporosis (OP) and explore their associations with clinical parameters.

Methods: A total of 123 patients with low back pain (59.1 ± 15.

Quantitative Multi-Parameter MRI Evaluation of Hashimoto's Thyroiditis Changes After Dietary Interventions.

BACKGROUND Hashimoto's thyroiditis is a common autoimmune disease. There are currently few studies utilizing multi-parametric magnetic resonance imaging (MRI) to investigate diffuse thyroid lesions such as Hashimoto's thyroiditis. This study aims to explore the value of multi-parametric MRI in assessing the progression of Hashimoto's thyroiditis.

The value of Gd-EOB-DTPA-enhanced MRI in the differential diagnosis of HCC with hyperintensity on HBP and FNH.

The aim was to investigate the differential diagnostic potential of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) features and establish a nomogram model for distinguishing hepatocellular carcinoma (HCC) from focal nodular hyperplasia (FNH) presenting with hyperintensity on the hepatobiliary phase (HBP). This retrospective study enrolled 80 patients with pathologically confirmed HCC or FNH who underwent Gd-EOB-DTPA-enhanced MRI between January 2017 and December 2020. All lesions exhibited hyperintensity on HBP.

AI-based large-scale screening of gastric cancer from noncontrast CT imaging.

Early detection through screening is critical for reducing gastric cancer (GC) mortality. However, in most high-prevalence regions, large-scale screening remains challenging due to limited resources, low compliance and suboptimal detection rate of upper endoscopic screening. Therefore, there is an urgent need for more efficient screening protocols.

Restoration of submerged vegetation modulates microbial communities to decrease nitrogen and phosphorus loads in sediment-water systems.

The release of nitrogen and phosphorus from sediments, known as internal nutrient loading, plays a crucial role in determining the eutrophic state of lakes and the timeframe for their ecological recovery. The restoration of submerged macrophytes is considered an effective measure to improve lake eutrophication. However, the impact of submerged macrophytes restoration on the storage and transformation mechanisms of nitrogen and phosphorus in lake sediment-water systems has not yet been systematically studied.

Thyroid antibodies in Hashimoto's thyroiditis patients are positively associated with inflammation and multiple symptoms.

Hashimoto's thyroiditis (HT) is an autoimmune disease, characterized by abnormal elevation in thyroid peroxidase antibody (TPO-Ab) and/or thyroglobulin antibody (TG-Ab). Patients have multiple symptoms despite adequate hormone substitution. In the present study, we aimed to quantify the relationship between thyroid antibodies and multiple symptoms, inflammation and health-related life quality.

Case report: Clinical, imaging, and genetic characteristics of type B niemann pick disease combined with segawa syndrome diagnosed via dual gene sequencing.

Niemann Pick disease B (NPB) often presents with hepatosplenomegaly and lung pathological changes, but it usually does not present with central nervous system symptoms. This report presents the unique case of a 21-year-old woman with a 10-year history of hard skin and hepatosplenomegaly. Genetic sequencing revealed NPB and also suggested Segawa syndrome.

MRI quantitative assessment of the effects of low-carbohydrate therapy on Hashimoto's thyroiditis.

Objective: Hashimoto's thyroiditis is an inflammatory disease, and research suggests that a low-carbohydrate diet may have potential anti-inflammatory effects. This study aims to utilize Dixon-T2-weighted imaging (WI) sequence for a semi-quantitative assessment of the impact of a low-carbohydrate diet on the degree of thyroid inflammation in patients with Hashimoto's thyroiditis.

Methods: Forty patients with Hashimoto's thyroiditis were recruited for this study and randomly divided into two groups: one with a normal diet and the other with a low-carbohydrate diet.

Cervical clear cell carcinoma: Case report and literature review.

Rationale: Clear cell carcinoma (CCC) is a highly invasive malignant tumor. CCCs of the female reproductive system occur mostly in the endometrium and ovaries and rarely in the cervix. So, it is difficult to diagnose cervical clear cell carcinoma (CCAC) on imaging.

Optimizing lung biopsy procedures:Comparative analysis of diagnostic efficacy and safety in experimental low-dose, conventional low-dose, and standard-dose CT-guided approaches.

Purpose: Lung cancer is a major cause of cancer-related deaths, emphasizing the importance of early diagnosis. CT-guided percutaneous lung biopsy(CT-PLB) is a valuable method for diagnosing lung lesions, but multiple scans can elevate radiation exposure. This study aims to compare diagnostic efficacy and safety across different CT-PLB protocols.

Magnetic resonance imaging for the diagnosis of malignant mixed Mullerian tumor of ovary: Two case reports.

Rationale: Malignant mixed Mullerian tumor (MMMT) is also known as carcinosarcoma, mostly occurring in the uterus, and occurred in ovary is very rare. The disease is highly aggressive. Two cases of MMMT of ovary and their imaging characteristics were collected in our study.

Diagnostic Value of MRI Features in Dual-phenotype Hepatocellular Carcinoma: A Preliminary Study.

This study aimed to explore the magnetic resonance imaging (MRI) features of dual-phenotype hepatocellular carcinoma (DPHCC) and their diagnostic value.The data of 208 patients with primary liver cancer were retrospectively analysed between January 2016 and June 2021. Based on the pathological diagnostic criteria, 27 patients were classified into the DPHCC group, 113 patients into the noncholangiocyte-phenotype hepatocellular carcinoma (NCPHCC) group, and 68 patients with intrahepatic cholangiocarcinoma (ICC) were classified into the ICC group.

Primary vaginal signet ring cell carcinoma.

Primary vaginal cancer is rare, accounting for only 2% of all gynecological malignant tumors. Primary vaginal cell carcinoma is mainly squamous cell carcinoma, accounting for about 90%, and adenocarcinoma only accounts for 8-10%. Primary signet ring cell carcinoma of vagina is rare and has not been reported in the literature.

Wandering small intestinal stromal tumor: A case report.

Background: The occurrence of gastrointestinal stromal tumors (GISTs) in the small intestine is rare, and a case of wandering small intestinal stromal tumor has been rarely reported to date. Dissemination of this case can help inform future diagnosis and effective treatment.

Case Summary: A 68-year-old patient presented to us with tarry stools.

Snail communities increase submerged macrophyte growth by grazing epiphytic algae and phytoplankton in a mesocosm experiment.

The relationships between producers (e.g., macrophytes, phytoplankton and epiphytic algae) and snails play an important role in maintaining the function and stability of shallow ecosystems.

A radiologic diagnostic scoring model based on CT features for differentiating gastric schwannoma from gastric gastrointestinal stromal tumors.

We aimed to further explore the CT features of gastric schwannoma (GS), propose and validate a convenient diagnostic scoring system to distinguish GS from gastric gastrointestinal stromal tumors (GISTs) preoperatively. 170 patients with submucosal tumors pathologically confirmed (GS n=35; gastric GISTs n=135) from Hospital 1 were analyzed retrospectively as the training cohort, and 72 patients (GS=11; gastric GISTs=61) from Hospital 2 were enrolled as the validation cohort. We searched for significant CT imaging characteristics and constructed the scoring system via binary logistic regression and converted regression coefficients to weighted scores.

High-resolution computed tomography findings independently predict epidermal growth factor receptor mutation status in ground-glass nodular lung adenocarcinoma.

Background: For lung adenocarcinoma with epidermal growth factor receptor (EGFR) gene mutation, small molecule tyrosine kinase inhibitors are more effective. Some patients could not obtain enough histological specimens for EGFR gene mutation detection. Specific imaging features can predict EGFR mutation status to a certain extent.

A scoring model for radiologic diagnosis of gastric leiomyomas (GLMs) with contrast-enhanced computed tomography (CE-CT): Differential diagnosis from gastrointestinal stromal tumors (GISTs).

Objectives: To investigate CT findings and develop a diagnostic score model to differentiate GLMs from GISTs.

Methods: This retrospective study included 109 patients with pathologically confirmed GLMs (n = 46) and GISTs (n = 63) from January 2013 to August 2018 who received CE-CT before surgery. Demographic and radiological features was collected, including lesion location, contour, presence or absence of intralesional necrosis and ulceration, growth pattern, whether the tumor involved EGJ, the long diameter (LD) /the short diameter (SD) ratio, pattern and degree of lesion enhancement.

A multi-class scoring system based on CT features for preoperative prediction in gastric gastrointestinal stromal tumors.

Our study aimed to establish and validate a multi-class scoring system for preoperative gastric gastrointestinal stromal tumors (GISTs) risk stratifications based on CT features. 150 gastric GIST patients who underwent contrast-enhanced CT examination and surgical resection from hospital 1 were retrospectively analyzed as the training cohort, and 61 patients from hospitals 2 and 3 were included as the validation cohort. A model was established by logistic regression analysis and weighted to be a scoring model.

Multimodality magnetic resonance imaging for the diagnosis of high-flow priapism following a straddle injury: A case report.

Rationale: Priapism is a common urologic emergency, but high-flow penile priapism (HFP) caused by trauma is very rare. Therefore, HFP diagnosis and treatment are still not standardized.

Patient Concerns: A 29-year-old man was admitted to the urology department of our hospital on August 01, 2019, due to "persistent penile erection caused by a straddle injury.

Submerged Vegetation and Water Quality Degeneration From Serious Flooding in Liangzi Lake, China.

In shallow lake ecosystems, flooding is a key disturbance factor of aquatic vegetation. Aquatic plants, especially submerged plants, play key roles in water ecosystems. Liangzi Lake experienced severe flooding in July 2010, and the elevated water levels lasted for 3 months.